Cognitive Affective & Behavioral Neuroscience最新文献_第4页

Effects of one session of theta or high alpha neurofeedback on EEG activity and working memory. 一个疗程的θ或高α神经反馈对脑电图活动和工作记忆的影响。

IF 2.5 3区医学

Cognitive Affective & Behavioral Neuroscience Pub Date : 2024-12-01 Epub Date: 2024-09-25 DOI: 10.3758/s13415-024-01218-4

Samy Chikhi, Nadine Matton, Marie Sanna, Sophie Blanchet

{"title":"Effects of one session of theta or high alpha neurofeedback on EEG activity and working memory.","authors":"Samy Chikhi, Nadine Matton, Marie Sanna, Sophie Blanchet","doi":"10.3758/s13415-024-01218-4","DOIUrl":"10.3758/s13415-024-01218-4","url":null,"abstract":"Neurofeedback techniques provide participants immediate feedback on neuronal signals, enabling them to modulate their brain activity. This technique holds promise to unveil brain-behavior relationship and offers opportunities for neuroenhancement. Establishing causal relationships between modulated brain activity and behavioral improvements requires rigorous experimental designs, including appropriate control groups and large samples. Our primary objective was to examine whether a single neurofeedback session, designed to enhance working memory through the modulation of theta or high-alpha frequencies, elicits specific changes in electrophysiological and cognitive outcomes. Additionally, we explored predictors of successful neuromodulation. A total of 101 healthy adults were assigned to groups trained to increase frontal theta, parietal high alpha, or random frequencies (active control group). We measured resting-state EEG, working memory performance, and self-reported psychological states before and after one neurofeedback session. Although our analyses revealed improvements in electrophysiological and behavioral outcomes, these gains were not specific to the experimental groups. An increase in the frequency targeted by the training has been observed for the theta and high alpha groups, but training designed to increase randomly selected frequencies appears to induce more generalized neuromodulation compared with targeting a specific frequency. Among all the predictors of neuromodulation examined, resting theta and high alpha amplitudes predicted specifically the increase of those frequencies during the training. These results highlight the challenge of integrating a control group based on enhancing randomly selected frequency bands and suggest potential avenues for optimizing interventions (e.g., by including a control group trained in both up- and down-regulation).","PeriodicalId":50672,"journal":{"name":"Cognitive Affective & Behavioral Neuroscience","volume":" ","pages":"1065-1083"},"PeriodicalIF":2.5,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142331742","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Electrodermal lability and sensorimotor preparation: effects on reaction time, contingent negative variation, and heart rate. 皮电不稳定性和感觉运动准备：对反应时间、或然性负变异和心率的影响。

IF 2.5 3区医学

Cognitive Affective & Behavioral Neuroscience Pub Date : 2024-12-01 Epub Date: 2024-08-14 DOI: 10.3758/s13415-024-01206-8

Heinz Zimmer, Fabian Richter

{"title":"Electrodermal lability and sensorimotor preparation: effects on reaction time, contingent negative variation, and heart rate.","authors":"Heinz Zimmer, Fabian Richter","doi":"10.3758/s13415-024-01206-8","DOIUrl":"10.3758/s13415-024-01206-8","url":null,"abstract":"Electrodermal lability is a trait-like measure of spontaneous sympathetic resting activity. In the present study, we addressed whether interindividual differences in this lability have an impact on the reaction time (RT) and on two physiological indicators of a goal-oriented sensorimotor preparation in a long-running, forewarned RT task (S1-S2 paradigm). The two indicators were the brain's contingent negative variation (CNV) and a heart rate deceleration (HRD). The interindividual differences were determined by counting spontaneous skin conductance fluctuations during a 5-min resting phase and dividing the subjects into two groups: individuals below (stable) and above (labile) the median of these fluctuations. In the task, labile individuals had a shorter RT compared with stable individuals and showed in the final phase of preparation in both physiological indicators the stronger response. Thus, lability-dependent effects in forewarned RT tasks cannot be explained by differences in stimulus-driven or passively controlled processes alone. Rather, goal-oriented, deliberately controlled processes that serve to adequately prepare for an imperative stimulus-the S2 in our paradigm-also must be considered to explain them. Labile individuals not only react faster than stable ones but also intentionally prepare themselves more appropriately for the imperative stimulus. A norepinephrine hypothesis focusing on the tonic activity of the locus coeruleus (LC) is proposed as an explanation for these and other lability-dependent effects. The frequency of spontaneous electrodermal fluctuations at rest may represent a peripheral, noninvasive, and easily measurable indicator of the baseline LC activity during wakefulness.","PeriodicalId":50672,"journal":{"name":"Cognitive Affective & Behavioral Neuroscience","volume":" ","pages":"1155-1166"},"PeriodicalIF":2.5,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11525398/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141983811","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The subcortical role in executive functions: Neural mechanisms of executive inhibition in the flanker task. 皮层下在执行功能中的作用：侧翼任务中执行抑制的神经机制

IF 2.5 3区医学

Cognitive Affective & Behavioral Neuroscience Pub Date : 2024-12-01 Epub Date: 2024-09-05 DOI: 10.3758/s13415-024-01215-7

Nofar Strommer, Hadas Okon-Singer, Shai Gabay

{"title":"The subcortical role in executive functions: Neural mechanisms of executive inhibition in the flanker task.","authors":"Nofar Strommer, Hadas Okon-Singer, Shai Gabay","doi":"10.3758/s13415-024-01215-7","DOIUrl":"10.3758/s13415-024-01215-7","url":null,"abstract":"While executive functions (EFs) have traditionally been linked to the cerebral cortex, our understanding of EFs has evolved with increasing evidence pointing to the involvement of cortico-subcortical networks. Despite the importance of investigating EFs within this broader context, the functional contributions of subcortical regions to these processes remain largely unexplored. This study addresses this gap by specifically examining the involvement of subcortical regions in executive inhibition, as measured by the classic Eriksen flanker task. In this study, we used a stereoscope to differentiate between subcortical (monocular) and cortical (mostly binocular) visual pathways in EF processes. Our findings indicate that monocular visual pathways play a crucial role in representing executive conflict, which necessitates cortical involvement. The persistence of a monoptic advantage in conflict representation highlights the substantial contribution of subcortical regions to these executive processes. This exploration of subcortical involvement in executive inhibition provides valuable insights into the intricate relationships between cortical and subcortical regions in EFs.","PeriodicalId":50672,"journal":{"name":"Cognitive Affective & Behavioral Neuroscience","volume":" ","pages":"1023-1030"},"PeriodicalIF":2.5,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11525269/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142141611","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The virtual disengagement hypothesis: A neurophysiological framework for reduced empathy on social media. 虚拟脱离假说：社交媒体上共鸣减少的神经生理学框架。

IF 2.5 3区医学

Cognitive Affective & Behavioral Neuroscience Pub Date : 2024-12-01 Epub Date: 2024-08-26 DOI: 10.3758/s13415-024-01212-w

Maria Tavares, Ben Rein

{"title":"The virtual disengagement hypothesis: A neurophysiological framework for reduced empathy on social media.","authors":"Maria Tavares, Ben Rein","doi":"10.3758/s13415-024-01212-w","DOIUrl":"10.3758/s13415-024-01212-w","url":null,"abstract":"Social media is a hotbed of interpersonal conflict and aggression. Platforms such as Twitter and Instagram are used by more than 62% of the global population, facilitating billions of user interactions every day. However, many of these exchanges involve hostile, insensitive, and antisocial behaviors. This raises the question: is empathy blunted on social media? Substantial evidence demonstrates that humans tend to behave more rudely in virtual settings, but considering the scarcity of physiological data collected under these circumstances, it remains unclear how the neural systems guiding social cognition and empathy may function differently in online interactions. We propose the \"Virtual Disengagement Hypothesis,\" a conceptual framework to explain the prevalence of hostility online. It posits that interactions occurring on social media omit social cues that facilitate the assessment of a social partner's affective state, such as facial expressions and vocal tone, and thus fail to sufficiently recruit brain circuitry involved in empathy, such as the anterior cingulate cortex, insula, and prefrontal cortex. Additionally, interactions on social media occur asynchronously and in a \"replayed\" context, which may further limit recruitment of empathy systems. As a result of this diminished sensitivity to others' states, users may be predisposed to inconsiderate or outright antisocial behaviors. Given the massive and growing base of users on these platforms, we urge researchers to expand efforts that focus on neuroimaging in virtual settings with a particular emphasis on developing social media-relevant behavioral designs.","PeriodicalId":50672,"journal":{"name":"Cognitive Affective & Behavioral Neuroscience","volume":" ","pages":"965-971"},"PeriodicalIF":2.5,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142074481","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Abstract task sequence initiation deficit dissociates anxiety disorders from obsessive-compulsive disorder and healthy controls. 摘要任务序列启动缺陷将焦虑症与强迫症和健康对照组区分开来。

IF 2.5 3区医学

Cognitive Affective & Behavioral Neuroscience Pub Date : 2024-12-01 Epub Date: 2024-07-31 DOI: 10.3758/s13415-024-01207-7

Hannah Doyle, Christina L Boisseau, Sarah L Garnaat, Steven A Rasmussen, Theresa M Desrochers

{"title":"Abstract task sequence initiation deficit dissociates anxiety disorders from obsessive-compulsive disorder and healthy controls.","authors":"Hannah Doyle, Christina L Boisseau, Sarah L Garnaat, Steven A Rasmussen, Theresa M Desrochers","doi":"10.3758/s13415-024-01207-7","DOIUrl":"10.3758/s13415-024-01207-7","url":null,"abstract":"In everyday life, humans perform sequences of tasks. These tasks may be disrupted in people with obsessive-compulsive disorder (OCD). Symptoms, such as compulsions, can be considered sequential and often cause repetitions of tasks that disrupt daily living (e.g., checking the stove while cooking). Motor sequences have been used to study behavioral deficits in OCD. However, not all sequences are motor sequences. Some are more \"abstract\" in that they are composed of a series of tasks (e.g., chopping and stirring) rather than being dependent on individual actions or stimuli. These abstract task sequences require cognitive control mechanisms for their execution. Although theory has proposed deficits in these sequences in OCD as well, they have not been directly investigated. We tested the hypotheses that OCD participants exhibit deficits in the control mechanisms specific to abstract task sequences and more general flexible behavior (measured with task switching within the sequences), relative to health controls (HCs) and clinical controls (participants with anxiety disorders [ANX]). A total of 112 participants completed abstract task sequences consisting of simple categorization tasks. Surprisingly, participants with OCD did not perform worse than HCs or ANX. However, ANX participants showed impairments specific to sequential control that did not extend to more general flexible control. Thus, we showed a novel behavioral dissociation between OCD and ANX specific to abstract task sequential control. These results also implicate deficits in specific frontal sequential control neural circuitry in ANX and not in OCD, where implicit sequential deficits may more closely align with striatal circuits.","PeriodicalId":50672,"journal":{"name":"Cognitive Affective & Behavioral Neuroscience","volume":" ","pages":"1186-1201"},"PeriodicalIF":2.5,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11527554/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141861458","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Distributed associations among white matter hyperintensities and structural brain networks with fluid cognition in healthy aging. 白质高密度和大脑结构网络与健康老龄化的流体认知之间的分布式关联。

IF 2.5 3区医学

Cognitive Affective & Behavioral Neuroscience Pub Date : 2024-12-01 Epub Date: 2024-09-20 DOI: 10.3758/s13415-024-01219-3

Marc D Rudolph, Jessica R Cohen, David J Madden

{"title":"Distributed associations among white matter hyperintensities and structural brain networks with fluid cognition in healthy aging.","authors":"Marc D Rudolph, Jessica R Cohen, David J Madden","doi":"10.3758/s13415-024-01219-3","DOIUrl":"10.3758/s13415-024-01219-3","url":null,"abstract":"White matter hyperintensities (WMHs) are associated with age-related cognitive impairment and increased risk of Alzheimer's disease. However, the manner by which WMHs contribute to cognitive impairment is unclear. Using a combination of predictive modeling and network neuroscience, we investigated the relationship between structural white matter connectivity and age, fluid cognition, and WMHs in 68 healthy adults (18-78 years). Consistent with previous work, WMHs were increased in older adults and exhibited a strong negative association with fluid cognition. Extending previous work, using predictive modeling, we demonstrated that age, WMHs, and fluid cognition were jointly associated with widespread alterations in structural connectivity. Subcortical-cortical connections between the thalamus/basal ganglia and frontal and parietal regions of the default mode and frontoparietal networks were most prominent. At the network level, both age and WMHs were negatively associated with network density and communicability, and positively associated with modularity. Spatially, WMHs were most prominent in arterial zones served by the middle cerebral artery and associated lenticulostriate branches that supply subcortical regions. Finally, WMHs overlapped with all major white matter tracts, most prominently in tracts that facilitate subcortical-cortical communication and are implicated in fluid cognition, including the anterior thalamic-radiations and forceps minor. Finally, results of mediation analyses suggest that whole-brain WMH load influences age-related decline in fluid cognition. Thus, across multiple levels of analysis, we showed that WMHs were increased in older adults and associated with altered structural white matter connectivity and network topology involving subcortical-cortical pathways critical for fluid cognition.","PeriodicalId":50672,"journal":{"name":"Cognitive Affective & Behavioral Neuroscience","volume":" ","pages":"1121-1140"},"PeriodicalIF":2.5,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11525275/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142300060","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Neural mechanisms of altruistic decision-making: EEG functional connectivity network analysis. 利他决策的神经机制：脑电图功能连接网络分析

IF 2.5 3区医学

Cognitive Affective & Behavioral Neuroscience Pub Date : 2024-12-01 Epub Date: 2024-08-29 DOI: 10.3758/s13415-024-01214-8

Dina G Mitiureva, Evgenia O Terlichenko, Veronika M Zubko, Polina I Kabanova, Vasilisa D Abrosimova, Sofya M Skripkina, Elizaveta V Krivchenkova, Daria M Verkholaz, Anna S Borodkina, Alisa V Komarova, Andrey A Kiselnikov

{"title":"Neural mechanisms of altruistic decision-making: EEG functional connectivity network analysis.","authors":"Dina G Mitiureva, Evgenia O Terlichenko, Veronika M Zubko, Polina I Kabanova, Vasilisa D Abrosimova, Sofya M Skripkina, Elizaveta V Krivchenkova, Daria M Verkholaz, Anna S Borodkina, Alisa V Komarova, Andrey A Kiselnikov","doi":"10.3758/s13415-024-01214-8","DOIUrl":"10.3758/s13415-024-01214-8","url":null,"abstract":"Altruism is an enigmatic form of prosocial behavior, characterized by diverse motivations and significant interindividual differences. Studying neural mechanisms of altruism is crucial to identify objective markers of pro- and antisocial tendencies in behavior. This study was designed to delve into the mechanisms of altruism by analyzing EEG-based functional connectivity patterns within the framework of the network approach. To experimentally induce a situation of altruistic decision-making, we employed the Pain versus Gain (PvsG) task, which implies making choices concerning financial self-benefit and pain of the other. Our results reveal that the behavioral measure of altruism in the experiment correlated with emotional empathy, which is in line with the \"empathy-altruism\" hypothesis. Applying the network approach to EEG functional connectivity analysis, we discovered that the very process of decision-making in the PvsG is characterized by the synchronous activity of structures in the right hemisphere, which are involved in empathy for pain. The prosociality of decisions was reflected in functional connectivity between the rostral ACC and orbital IFG in the left hemisphere and the overall network centrality of the caudal ACC. This finding additionally points to the distinct functional roles of the ACC subregions in altruistic decision-making. The proposed neural mechanisms of altruism can further be used to identify neurophysiological markers of prosociality in behavior.","PeriodicalId":50672,"journal":{"name":"Cognitive Affective & Behavioral Neuroscience","volume":" ","pages":"1109-1120"},"PeriodicalIF":2.5,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142094132","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Enhancing cognitive control of our decisions: Making the most of humor during the IGT in females and males. 加强对决策的认知控制：在女性和男性的 IGT 中充分利用幽默。

IF 2.5 3区医学

Cognitive Affective & Behavioral Neuroscience Pub Date : 2024-12-01 Epub Date: 2024-09-05 DOI: 10.3758/s13415-024-01210-y

Jorge Flores-Torres, Kateri McRae, German Campos-Arteaga, Lydia Gómez-Pérez

{"title":"Enhancing cognitive control of our decisions: Making the most of humor during the IGT in females and males.","authors":"Jorge Flores-Torres, Kateri McRae, German Campos-Arteaga, Lydia Gómez-Pérez","doi":"10.3758/s13415-024-01210-y","DOIUrl":"10.3758/s13415-024-01210-y","url":null,"abstract":"We studied the impact of humor on the Iowa Gambling Task (IGT) decision-making performance and the cognitive control exerted during this task, considering sex as a moderator, and examined whether cognitive control mediated the influence of humor on decision-making. Sixty participants (30 females) performed an extended version of the IGT (500 trials divided into 20 blocks). We randomly assigned them to either an experimental group (Humor Group; Hg; n = 30), where humorous videos were interspersed in the decision-making trials or a control group (Non-Humor Group; NHg; n = 30), where nonhumorous videos were interspersed in the decision-making trials. We recorded participant performance and feedback-related negativity (FRN) and P3b event-related potentials (ERP) during IGT feedback as task monitoring and attention allocation indicators, respectively. We expected that whereas humor would improve IGT decision-making under risk in females during the last blocks (17-20) as well as cognitive control (specifically attention allocation and task monitoring) across the entire IGT, it would impair them in males. Contrary to our expectations, humor improved IGT decision-making under risk for both sexes (specifically at blocks 19 and 20) and attention allocation for most IGT blocks (P3b amplitudes). However, humor impaired IGT decision-making under ambiguity in males during the block six and task monitoring (FRN amplitudes) for most IGT blocks. Attention allocation did not mediate the beneficial effect of humor on decision-making under risk in either sex. Task monitoring decrements fully mediated the humor's detrimental influence on men's decision-making under ambiguity during block six.","PeriodicalId":50672,"journal":{"name":"Cognitive Affective & Behavioral Neuroscience","volume":" ","pages":"1031-1047"},"PeriodicalIF":2.5,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11525253/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142141610","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Correction: Implementations of sign- and goal-tracking behavior in humans: A scoping review. 更正：人类标志和目标追踪行为的实施：范围综述。

IF 2.5 3区医学

Cognitive Affective & Behavioral Neuroscience Pub Date : 2024-11-26 DOI: 10.3758/s13415-024-01249-x

Michelle Heck, Nancy Durieux, Patrick Anselme, Etienne Quertemont

引用次数: 0

Atypical pupil-linked arousal induced by low-risk probabilistic choices, and intolerance of uncertainty in adults with ASD. 低风险概率选择引起的非典型瞳孔联动唤醒，以及患有 ASD 的成年人对不确定性的不容忍。

IF 2.5 3区医学

Cognitive Affective & Behavioral Neuroscience Pub Date : 2024-11-19 DOI: 10.3758/s13415-024-01227-3

Kristina I Pultsina, Tatiana A Stroganova, Galina L Kozunova, Andrey O Prokofyev, Aleksandra S Miasnikova, Anna M Rytikova, Boris V Chernyshev

{"title":"Atypical pupil-linked arousal induced by low-risk probabilistic choices, and intolerance of uncertainty in adults with ASD.","authors":"Kristina I Pultsina, Tatiana A Stroganova, Galina L Kozunova, Andrey O Prokofyev, Aleksandra S Miasnikova, Anna M Rytikova, Boris V Chernyshev","doi":"10.3758/s13415-024-01227-3","DOIUrl":"https://doi.org/10.3758/s13415-024-01227-3","url":null,"abstract":"Adults with autism spectrum disorder (ASD) experience stress when operating in a probabilistic environment, even if it is familiar, but the underlying mechanisms remain unclear. Their decision-making may be affected by the uncertainty aversion implicated in ASD and associated with increased autonomic arousal. Previous studies have shown that in neurotypical (NT) people, decisions with predictably better outcomes are less stressful and elicit smaller pupil-linked arousal than those involving exploration. Here, in a sample of 46 high-functioning ASD and NT participants, using mixed-effects model analysis, we explored pupil-linked arousal and behavioral performance in a probabilistic reward learning task with a stable advantage of one choice option over the other. We found that subjects with ASD learned and preferred advantageous probabilistic choices at the same rate and to the same extent as NT participants, both in terms of choice ratio and response time. Although both groups exhibited similar predictive behaviors, learning to favor advantageous choices led to increased pupillary arousal for these choices in the ASD group, while it caused a decrease in pupillary arousal in the NT group. Moreover, greater pupil-linked arousal during decisions with higher expected value correlated with greater degree of self-reported intolerance of uncertainty in everyday life. Our results suggest that in a nonvolatile probabilistic environment, objectively good predictive abilities in people with ASD are coupled with elevated physiological stress and subjective uncertainty regarding the decisions with the best possible but still uncertain outcome that contributes to their intolerance of uncertainty.","PeriodicalId":50672,"journal":{"name":"Cognitive Affective & Behavioral Neuroscience","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2024-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142677522","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0