William Kuo, Christopher M Cirnigliaro, Anmol Doss, Noam Y Harel, Christopher P Cardozo, Steven Kirshblum, William A Bauman, Saikat Pal
{"title":"Mechanical competence of proximal tibia in persons with spinal cord injury: development of a computational framework to quantify torsional and compressive stiffness and strength.","authors":"William Kuo, Christopher M Cirnigliaro, Anmol Doss, Noam Y Harel, Christopher P Cardozo, Steven Kirshblum, William A Bauman, Saikat Pal","doi":"10.1080/10255842.2026.2749494","DOIUrl":"https://doi.org/10.1080/10255842.2026.2749494","url":null,"abstract":"<p><p>This study developed a framework to quantify the mechanical competence of the proximal tibia in spinal cord injury (SCI) and able-bodied (AB) participants. We created subject-specific finite element models of 53 proximal tibias (22 SCI, 5 AB) and quantified two torsional (stiffness, K<sub>t</sub> and ultimate strength, T<sub>ult</sub>) and two compressive (stiffness, K<sub>c</sub> and ultimate strength, C<sub>ult</sub>) metrics. We report the distributions of K<sub>t</sub>, T<sub>ult</sub>, K<sub>c</sub>, and C<sub>ult</sub>, and a minimum number of metrics required to quantify the mechanical competence of the proximal tibia. This work provides a foundation for confidence interval-based thresholds to predict fracture risk in persons with SCI.</p>","PeriodicalId":50640,"journal":{"name":"Computer Methods in Biomechanics and Biomedical Engineering","volume":" ","pages":"1-15"},"PeriodicalIF":1.9,"publicationDate":"2026-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149225223","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ekaterina Marchenko, Alexander Kozulin, Anna Vetrova, Marina Kovaleva, Gulsharat Baigonakova, Yuri Yasenchuk, Evgeniy Topolnitskiy, Tatiana Fomina
{"title":"Simulation-based evaluation of stretching behavior of NiTi wire-knitted implants for reconstructive plastic surgery.","authors":"Ekaterina Marchenko, Alexander Kozulin, Anna Vetrova, Marina Kovaleva, Gulsharat Baigonakova, Yuri Yasenchuk, Evgeniy Topolnitskiy, Tatiana Fomina","doi":"10.1080/10255842.2026.2739432","DOIUrl":"https://doi.org/10.1080/10255842.2026.2739432","url":null,"abstract":"<p><p>A comprehensive study of the mechanical response of a titanium nickelide (TiNi) wire-knitted implant was conducted through tensile testing and finite element simulation using the Bergström-Boyce hyperelastic model calibrated <i>via</i> MCalibration and solved in ANSYS. The elongation-load curves for both the ribbon tissue scaffold (RTS) and the composite samples consisting of a RTS with biological tissues sprouted therein (RTS/bio-tissue) demonstrated nonlinear superelastic behavior. Under longitudinal tension, the biological tissue and the RTS exhibited similar deformation patterns. An evaluation of the biomechanical compatibility between soft tissues and the knitted metallic scaffold revealed the closest correspondence for the 40-µm thick RTS with muscle tissue, and for the 60-µm thick RTS with skin. However, it was noted that the contact areas of the metal knitted loops have the potential to cause damage to biological tissue. A microscopic examination of the connective tissue integrated with the RTS indicated successful incorporation of the implant into the rat abdominal wall under physiological loads, with no observed damage to the host tissue. Both microscopic analysis and low-cycle tensile tests confirmed that the RTS, once implanted, exhibited a relative elongation of less than 16%. This value represents the ultimate longitudinal elongation threshold identified during the pre-operative quantitative assessment of biomechanical compatibility between the RTS and biological tissues.</p>","PeriodicalId":50640,"journal":{"name":"Computer Methods in Biomechanics and Biomedical Engineering","volume":" ","pages":"1-15"},"PeriodicalIF":1.9,"publicationDate":"2026-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149185862","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comparing Maximally Collapsing Metric Learning and Optimized Tunable Q-Wavelet Transform for Schizophrenia Identification Using EEG Signals.","authors":"Rafik Djemili","doi":"10.1080/10255842.2026.2743643","DOIUrl":"https://doi.org/10.1080/10255842.2026.2743643","url":null,"abstract":"<p><p>Electroencephalography (EEG) is a noninvasive technique for recording brain electrical activity and supporting the assessment of psychiatric disorders. This study proposes a framework for distinguishing individuals with Schizophrenia (SZ) from healthy subjects using EEG data. The approach employs a transformer based on Maximally Collapsing Metric Learning (MCML) applied to feature-vector matrices and compares it with optimized Tunable Q-Wavelet Transform (TQWT) decomposition. Eight nonlinear features are extracted from both approaches and evaluated using *k*-Nearest Neighbor (*k*-NN), Optimized Decision Tree (ODT), and Deep Neural Network (DNN) classifiers. Results achieve accuracies of 100%, 99.94%, and 99.91%, respectively, using one electrode channel.</p>","PeriodicalId":50640,"journal":{"name":"Computer Methods in Biomechanics and Biomedical Engineering","volume":" ","pages":"1-17"},"PeriodicalIF":1.9,"publicationDate":"2026-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149148850","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Gait-based neurodegenerative disease classification using multimodal temporal-spectral representations and a dual-branch CNN.","authors":"İsmihan Gül Ozeloglu, Eda Akman Aydin","doi":"10.1080/10255842.2026.2736243","DOIUrl":"https://doi.org/10.1080/10255842.2026.2736243","url":null,"abstract":"<p><p>Neurodegenerative diseases (NDDs) often cause gait impairments with overlapping motor symptoms, complicating multi-class discrimination. This study proposes a lightweight dual-branch convolutional neural network integrating recurrence plots and spectrogram representations of vertical ground reaction force signals to classify Parkinson's disease, amyotrophic lateral sclerosis, Huntington's disease, and healthy controls. Evaluated on the Gait in NDDs Dataset comprising 64 subjects, the proposed framework achieved 96.15% accuracy, outperforming recurrence-based (94.19%) and spectrogram-based (95.75%) single-branch models. The findings demonstrate that combining complementary temporal recurrence and spectral information improves discrimination of neurodegenerative gait patterns while maintaining low computational complexity.</p>","PeriodicalId":50640,"journal":{"name":"Computer Methods in Biomechanics and Biomedical Engineering","volume":" ","pages":"1-14"},"PeriodicalIF":1.9,"publicationDate":"2026-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149139111","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A dual-channel deep learning framework integrating preoperative and intraoperative multi-phase data for predicting post-ablation recurrence in atrial fibrillation.","authors":"Mengfei Wu, Shouyang Zhu, Xingye Chen, Yuan Wang, Yu Wang, Hao Su","doi":"10.1080/10255842.2026.2736287","DOIUrl":"https://doi.org/10.1080/10255842.2026.2736287","url":null,"abstract":"<p><p>Predicting atrial fibrillation (AF) recurrence after catheter ablation is essential for optimizing postoperative management. This study developed the Ablation-Clinical Fusion Transformer (ACFT), a dual-channel framework integrating structured intraoperative ablation sequences with clinical indicators using Transformer and Multilayer Perceptron (MLP) architectures. Validated on real-world data, the model achieved an Area Under the Receiver Operating Characteristic curve of 0.844 (95% CI: 0.819, 0.869), representing a 7% improvement over standard benchmarks. This work provides an innovative approach for predicting AF recurrence after ablation and demonstrates significant potential for clinical application.</p>","PeriodicalId":50640,"journal":{"name":"Computer Methods in Biomechanics and Biomedical Engineering","volume":" ","pages":"1-12"},"PeriodicalIF":1.9,"publicationDate":"2026-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149128439","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yuchen Liang, Xuelin Gu, Jun Wang, Xiaoou Li, Lihong Pan
{"title":"Deep fusion for multimodal subtype classification of major depressive disorders based on TSCANet.","authors":"Yuchen Liang, Xuelin Gu, Jun Wang, Xiaoou Li, Lihong Pan","doi":"10.1080/10255842.2026.2731404","DOIUrl":"https://doi.org/10.1080/10255842.2026.2731404","url":null,"abstract":"<p><p>Major Depressive Disorder (MDD) represents a major global health burden, characterized by high recurrence rates and an increased risk of suicide. Traditional clinical diagnoses rely primarily on subjective scales, which limits their objectivity in accurately distinguishing MDD subtypes.To address these challenges, this study introduces a multimodal assessment framework that integrates EEG functional connectivity with clinical scale data.We developed TSCANet (Transformer Local-Global Graph Neural Network Scales Cross-Attention Network), a deep learning multimodal model designed to address the complexity of psychiatric data. TSCANet achieved classification accuracies of 82.62% and 81.36% in visual and auditory paradigms, respectively, outperforming single-modality models.</p>","PeriodicalId":50640,"journal":{"name":"Computer Methods in Biomechanics and Biomedical Engineering","volume":" ","pages":"1-23"},"PeriodicalIF":1.9,"publicationDate":"2026-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149128463","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jie Gao, Pengliang Ju, Lixiu Chen, Yuzan Li, Jingjuan Huang, Jie Wu
{"title":"A dual-stream multi-scale cross-attention network for pericardial effusion detection.","authors":"Jie Gao, Pengliang Ju, Lixiu Chen, Yuzan Li, Jingjuan Huang, Jie Wu","doi":"10.1080/10255842.2026.2736736","DOIUrl":"https://doi.org/10.1080/10255842.2026.2736736","url":null,"abstract":"<p><p>Early detection of pericardial effusion (PE) is clinically important because delayed diagnosis may cause severe cardiac complications. We propose a Dual-Stream Multi-Scale Cross-Attention Network (DS-MSCA) for automatic PE detection using simultaneously acquired electrocardiogram (ECG) and phonocardiogram (PCG) signals. Multi-scale Inception-ResNet encoders capture waveform and rhythm variations, while bidirectional cross-attention models cardiac electromechanical coupling. On a clinical dataset of 149 patients, DS-MSCA achieved 93.26% accuracy, 95.28% sensitivity, and a 95.01% F1-score. Attention maps and Grad-CAM++ showed that the model focused on clinically relevant heart-sound abnormalities while integrating complementary ECG information, supporting non-invasive PE screening.</p>","PeriodicalId":50640,"journal":{"name":"Computer Methods in Biomechanics and Biomedical Engineering","volume":" ","pages":"1-12"},"PeriodicalIF":1.9,"publicationDate":"2026-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149117985","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Xiangqian Zuo, Min Li, Xinjie Feng, Xinchen Yu, Jing Jiang
{"title":"Improving SpO<sub>2</sub> estimation accuracy under varying respiratory intensities using whale optimization and Gaussian process regression.","authors":"Xiangqian Zuo, Min Li, Xinjie Feng, Xinchen Yu, Jing Jiang","doi":"10.1080/10255842.2025.2504160","DOIUrl":"10.1080/10255842.2025.2504160","url":null,"abstract":"<p><p>Accurate and continuous monitoring of oxygen saturation (SpO<sub>2</sub>) is critical for managing respiratory disorders. This study investigates the influence of varying respiratory intensities on SpO<sub>2</sub> estimation and proposes an optimized predictive model to enhance accuracy. Photoplethysmography (PPG) signals were collected using a controlled laboratory simulator across SpO<sub>2</sub> levels ranging from 80% to 100% under six distinct respiratory intensity levels, generating a dataset of 12,250 signal segments. To improve estimation performance, a Gaussian Process Regression (GPR) model was developed, with its hyperparameters optimized using five distinct algorithms: Bayesian Optimization (BO), Genetic Algorithm (GA), Whale Optimization Algorithm (WOA), Grey Wolf Optimizer (GWO), and Particle Swarm Optimization (PSO). These optimization techniques were selected to encompass diverse computational paradigms, including probabilistic modeling, evolutionary strategies, and swarm intelligence, ensuring a robust comparative evaluation. Experimental results demonstrated that the WOA-optimized GPR (WOA-GPR) model exhibited superior performance across varying respiratory conditions, achieving a Mean Absolute Error (MAE) between 0.89 and 1.41 and a Root Mean Square Error (RMSE) between 0.63 and 0.86. Comparative analysis against other regression models, including Support Vector Regression (SVR) and Random Forest Regression (RFR), further confirmed the effectiveness of the WOA-GPR model. Finally, validation using real-world physiological data reinforced its reliability for practical applications. These findings underscore the potential of WOA-GPR as a promising approach for enhancing real-time SpO<sub>2</sub> estimation in health monitoring applications.</p>","PeriodicalId":50640,"journal":{"name":"Computer Methods in Biomechanics and Biomedical Engineering","volume":" ","pages":"3117-3129"},"PeriodicalIF":1.9,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144086408","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Numerical analysis of oscillating microbubbles coated with a lipid monolayer near a flexible tissue.","authors":"Ramyar Doustikhah, Saeed Dinarvand, Pedram Tehrani, Mohammad Eftekhari Yazdi, Gholamreza Salehi","doi":"10.1080/10255842.2025.2505651","DOIUrl":"10.1080/10255842.2025.2505651","url":null,"abstract":"<p><p>Over the past two decades, ultrasound has advanced as a non-invasive drug delivery method. However, cavitation may cause cytoskeletal damage and cell death. This study numerically analyzes a compressible lipid-coated bubble near flexible tissue using Lattice Boltzmann and finite element methods. At 200 and 400 KPa ultrasound pressures, results show increased shear stress, boundary deformation, and bubble dynamics. The elastic boundary raises the bubble's resonance frequency. Shear stress rises from 0.09 to 0.61 KPa and 0.11 to 1.1 KPa during compression and expansion. A multi-pseudo-potential LBM improves cavitation modeling, revealing how proximity to cells intensifies pressure effects.</p>","PeriodicalId":50640,"journal":{"name":"Computer Methods in Biomechanics and Biomedical Engineering","volume":" ","pages":"3141-3152"},"PeriodicalIF":1.9,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144112527","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mouaz Al Kouzbary, Joslyn Ker Xin Yeoh, Hamza Al Kouzbary, Jingjing Liu, Hanie Nadia Shasmin, Lai Kuan Tham, Nooranida Arifin, Noor Azuan Abu Osman
{"title":"Type two fuzzy logic control system for powered ankle-foot prosthesis: robust performance against terrain and speed variations.","authors":"Mouaz Al Kouzbary, Joslyn Ker Xin Yeoh, Hamza Al Kouzbary, Jingjing Liu, Hanie Nadia Shasmin, Lai Kuan Tham, Nooranida Arifin, Noor Azuan Abu Osman","doi":"10.1080/10255842.2025.2506791","DOIUrl":"10.1080/10255842.2025.2506791","url":null,"abstract":"<p><p>The development of powered prostheses' control systems is drifting away from discontinuous control systems based on the finite state machine (FSM), due to the issues of misclassification. Recent research focused on model-based control systems, most widely used is the hybrid zero dynamic (HZD). However, the HZD system depends on the model accuracy and number of feedback signals. Navigating different terrains is vital for independent mobility for people with lower-limb amputation. In this paper, we propose a control system based on Takagi-Sugeno-Kang (TSK) inference. The fuzzy system is based on Type 2 membership functions to accommodate the gait cycle uncertainties. To fulfil the design procedure, experiments were conducted to capture the ambulation data in different terrains. Twelve individuals participated in four experiments, a set of seven inertial measurement units (IMUs) were placed on the lower body. The data was used to assess the control system behaviour terrains and subjects' data. A model was built to represent the powered ankle-foot prosthesis, where the ground reaction force (GRF) and the target angular position were experimentally extracted and fed to the model. The control system was evaluated using three evaluation parameters (root mean square error (RMSE), mean absolute error (MAE) and normalized cross-correlation). The average RMSE is 3.22 ± 2.7 degree, and a high correlation of 96.73% can be observed. The performance matrix is uniform based on Kruskal-Wallis test (<i>p</i> = 0.9954), and effect size (Cramér's <i>V</i> = 0.02) indicated negligible practical significance of the change of speed and terrain on the control performance.</p>","PeriodicalId":50640,"journal":{"name":"Computer Methods in Biomechanics and Biomedical Engineering","volume":" ","pages":"3153-3166"},"PeriodicalIF":1.9,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144217456","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}