International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases最新文献

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Epidemiological and spatiotemporal analyses of HIV/AIDS prevalence among older adults in Sichuan, China between 2008 and 2019: A population-based study. 2008 - 2019年中国四川省老年人艾滋病毒/艾滋病流行病学和时空分析:一项基于人群的研究
IF 8.4
Feng-Shun Yuan, Li Liu, Lun-Hao Liu, Ya-Li Zeng, Ling-Lin Zhang, Fang He, Xiao-Jin Liu, Ju-Mei Li, Qian Liu, Meng-Jiao Xu, Lacuo Zhuoma, Ying Hu, Xiao-di Pei, Rong-Sheng Luan
{"title":"Epidemiological and spatiotemporal analyses of HIV/AIDS prevalence among older adults in Sichuan, China between 2008 and 2019: A population-based study.","authors":"Feng-Shun Yuan,&nbsp;Li Liu,&nbsp;Lun-Hao Liu,&nbsp;Ya-Li Zeng,&nbsp;Ling-Lin Zhang,&nbsp;Fang He,&nbsp;Xiao-Jin Liu,&nbsp;Ju-Mei Li,&nbsp;Qian Liu,&nbsp;Meng-Jiao Xu,&nbsp;Lacuo Zhuoma,&nbsp;Ying Hu,&nbsp;Xiao-di Pei,&nbsp;Rong-Sheng Luan","doi":"10.1016/j.ijid.2021.02.077","DOIUrl":"https://doi.org/10.1016/j.ijid.2021.02.077","url":null,"abstract":"<p><strong>Objectives: </strong>To describe epidemiological trends and spatial distributions of HIV/AIDS among older adults (aged ≥50) in Sichuan Province, China during 2008-19, and provide scientific reference for HIV/AIDS prevention, intervention and treatment.</p><p><strong>Methods: </strong>Data on HIV/AIDS cases reported in 2008-19 was extracted from the Case Report System. The Cochran-Armitage trend test was used to determine epidemic trends. Spatial autocorrelation and space-time analysis were conducted with ArcGIS10.6 and ArcGIS Pro2.4, respectively.</p><p><strong>Results: </strong>A total of 77854 HIV/AIDS cases among older adults were included in the study. Newly reported cases increased from 320 in 2008 to 22189 in 2019, and the reported incidence rate (number of new reported cases/older adult population) rose from 0.001% to 0.077%. Infections through heterosexual transmission increased from 65.3% to 98.2% of total cases in older adults in this period. Spatial analysis at the county-level showed significant clustering throughout Sichuan, with the main hot spots concentrated in the southeast. Spatiotemporal analysis indicated that most of the southeastern counties/districts were Consecutive Hot Spots.</p><p><strong>Conclusions: </strong>Older adults have become a key population in the HIV/AIDS epidemic in Sichuan; comprehensive prevention and intervention measures targeted to older adults are urgently needed to control the spread of HIV/AIDS.</p>","PeriodicalId":505767,"journal":{"name":"International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases","volume":" ","pages":"769-775"},"PeriodicalIF":8.4,"publicationDate":"2021-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.ijid.2021.02.077","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25399541","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 13
Risk of chronic arthralgia and impact of pain on daily activities in a cohort of patients with chikungunya virus infection from Brazil. 巴西基孔肯雅病毒感染患者队列慢性关节痛风险及疼痛对日常活动的影响
IF 8.4
Monaíse M O Silva, Mariana Kikuti, Rosângela O Anjos, Moyra M Portilho, Viviane C Santos, Thaiza S F Gonçalves, Laura B Tauro, Patrícia S S Moreira, Leile C Jacob-Nascimento, Perla M Santana, Gúbio S Campos, André M Siqueira, Uriel Kitron, Mitermayer G Reis, Guilherme S Ribeiro
{"title":"Risk of chronic arthralgia and impact of pain on daily activities in a cohort of patients with chikungunya virus infection from Brazil.","authors":"Monaíse M O Silva,&nbsp;Mariana Kikuti,&nbsp;Rosângela O Anjos,&nbsp;Moyra M Portilho,&nbsp;Viviane C Santos,&nbsp;Thaiza S F Gonçalves,&nbsp;Laura B Tauro,&nbsp;Patrícia S S Moreira,&nbsp;Leile C Jacob-Nascimento,&nbsp;Perla M Santana,&nbsp;Gúbio S Campos,&nbsp;André M Siqueira,&nbsp;Uriel Kitron,&nbsp;Mitermayer G Reis,&nbsp;Guilherme S Ribeiro","doi":"10.1016/j.ijid.2021.03.003","DOIUrl":"https://doi.org/10.1016/j.ijid.2021.03.003","url":null,"abstract":"<p><strong>Objectives: </strong>To investigate risk factors for persistent arthralgia in patients with chikungunya, and describe its impact on daily activities.</p><p><strong>Methods: </strong>From September 2014 to July 2016, a surveillance study enrolled patients with acute febrile illness in Salvador, Brazil, and detected those with chikungunya virus infection using IgM enzyme-linked immunosorbent assay or reverse transcriptase polymerase chain reaction. Telephone follow-ups were performed to ascertain the progression of disease.</p><p><strong>Results: </strong>Of 153 followed cases, 65 (42.5%) reported chronic arthralgia that lasted >3 months, and 47 (30.7%) were still symptomatic at the time of the interview (approximately 1.5 years after symptom onset). Limitations in daily activities and mental distress were reported by 93.8% and 61.5% of those with chronic arthralgia, respectively. Female sex [risk ratio (RR) 1.79, 95% confidence interval (CI) 1.95-2.69] and age (RR 1.02 for each 1-year increase, 95% CI 1.01-1.03) were independent risk factors for chronic arthralgia. Chronic arthralgia was not associated with co-infection with dengue virus (RR 0.97, 95% CI 0.48-1.94) or chikungunya viral load at diagnosis (median chikungunya virus RNA of 5.60 and 5.52 log<sub>10</sub> copies/μL for those with and without chronic arthralgia, respectively; P = 0.75).</p><p><strong>Conclusions: </strong>These findings reinforce the high frequency of chronic chikungunya arthralgia, and highlight the substantial disability associated with the persistence of pain. Development of novel strategies to mitigate the transmission of chikungunya virus and to provide long-term medical assistance for patients with chikungunya are needed urgently.</p>","PeriodicalId":505767,"journal":{"name":"International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases","volume":" ","pages":"608-616"},"PeriodicalIF":8.4,"publicationDate":"2021-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.ijid.2021.03.003","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25448802","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 6
Effect of in-house crowding on childhood hospital admissions for acute respiratory infection: A matched case-control study in Bangladesh. 室内拥挤对急性呼吸道感染儿童入院的影响:孟加拉国的一项匹配病例对照研究。
IF 8.4
Moktarul Islam, Zeeba Zahra Sultana, Adiba Iqbal, Mohammad Ali, Ahmed Hossain
{"title":"Effect of in-house crowding on childhood hospital admissions for acute respiratory infection: A matched case-control study in Bangladesh.","authors":"Moktarul Islam,&nbsp;Zeeba Zahra Sultana,&nbsp;Adiba Iqbal,&nbsp;Mohammad Ali,&nbsp;Ahmed Hossain","doi":"10.1016/j.ijid.2021.03.002","DOIUrl":"https://doi.org/10.1016/j.ijid.2021.03.002","url":null,"abstract":"<p><strong>Objective: </strong>Despite previous studies conducted to identify potential household factors, no conclusive evidence exists regarding the effect of in-house crowding on hospitalization for acute respiratory infection (ARI) in Bangladesh. Hence, the aim of this study was to detect such an association in children aged 6-59 months.</p><p><strong>Methods: </strong>An age and sex-matched case-control study was conducted involving 348 children in Bangladesh. In-house crowding was measured by people-per-bedroom. Conditional logistic regression was performed to identify the association between in-house crowding and hospitalization for ARI.</p><p><strong>Results: </strong>In-house overcrowding was associated with a 2.9-fold (95% confidence interval 1.80-4.73) greater adjusted odds of hospitalization for ARI compared to children from less crowded houses. In-house overcrowding was common in rural areas and in households with a poor economic status. Suboptimal breastfeeding and household tobacco smoke exposure were found to prevail in overcrowded households.</p><p><strong>Conclusion: </strong>In-house overcrowding is associated with an increased risk of hospitalization for ARI in young children. Eliminating the fraction of the ARI burden due to in-house overcrowding will rely on increasing awareness regarding indoor air pollution and ventilation in the house and making efforts to avoid smoking in dwellings. Along with the management of crowding, child nutrition and exclusive breast-feeding requirements should be continued for a wide range of child health benefits.</p>","PeriodicalId":505767,"journal":{"name":"International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases","volume":" ","pages":"639-645"},"PeriodicalIF":8.4,"publicationDate":"2021-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.ijid.2021.03.002","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25462559","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 12
Human infection with an unknown species of Dracunculus in Vietnam. 越南人类感染一种未知的龙线虫。
IF 8.4
Pham Ngoc Thach, H Rogier van Doorn, Henry S Bishop, Mark S Fox, Sarah G H Sapp, Vitaliano A Cama, Le Van Duyet
{"title":"Human infection with an unknown species of Dracunculus in Vietnam.","authors":"Pham Ngoc Thach,&nbsp;H Rogier van Doorn,&nbsp;Henry S Bishop,&nbsp;Mark S Fox,&nbsp;Sarah G H Sapp,&nbsp;Vitaliano A Cama,&nbsp;Le Van Duyet","doi":"10.1016/j.ijid.2021.02.018","DOIUrl":"https://doi.org/10.1016/j.ijid.2021.02.018","url":null,"abstract":"<p><p>Guinea worm (GW) disease, caused by Dracunculus medinensis, is an almost eradicated waterborne zoonotic disease. The World Health Organization (WHO) currently lists GW as endemic in only five African countries. In July 2020, the Vietnamese public health surveillance system detected a hanging worm in a 23-year-old male patient, who did not report any travel to Africa or any country previously endemic for GW. The patient was hospitalized with symptoms of fatigue, anorexia, muscle aches, and abscesses, with worms hanging out of the skin in the lower limbs. The worms were retrieved from the lesions and microscopically examined in Vietnam, identifying structures compatible with Dracunculus spp. and L1-type larvae. A section of this parasite was sent to the Centers for Disease Control and Prevention (CDC) in Atlanta, United States, for confirmatory diagnosis of GW. The adult worm had cuticle structures compatible with Dracunculus parasites, although the length of L1 larvae was about 339 μm, substantially shorter than D. medinensis. DNA sequence analysis of the 18S small subunit rRNA gene confirmed that this parasite was not GW, and determined that the sample belonged to a Dracunculus sp. not previously reported in GenBank that clustered with the animal-infective Dracunculus insignis and Dracunculus lutrae, located in a different clade than D. medinensis. This study highlights the importance of effective public health surveillance systems and the collaborative work of local public health authorities from Vietnam with the WHO and CDC in efforts to achieve the eradication of GW.</p>","PeriodicalId":505767,"journal":{"name":"International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases","volume":" ","pages":"739-742"},"PeriodicalIF":8.4,"publicationDate":"2021-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.ijid.2021.02.018","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25492865","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 8
Chikungunya virus ECSA lineage reintroduction in the northeasternmost region of Brazil. 基孔肯雅病毒ECSA谱系在巴西最东北地区的重新引入。
IF 8.4
Joilson Xavier, Vagner Fonseca, Joao Felipe Bezerra, Manoella do Monte Alves, Maria Angélica Mares-Guia, Ingra Morales Claro, Ronaldo de Jesus, Talita Adelino, Emerson Araújo, Karina Ribeiro Leite Jardim Cavalcante, Stephane Tosta, Themis Rocha de Souza, Flavia Emanuelle Moreira da Cruz, Allison de Araújo Fabri, Elaine Cristina de Oliveira, Noely Fabiana Oliveira de Moura, Rodrigo Fabiano do Carmo Said, Carlos Frederico Campelo de Albuquerque, Vasco Azevedo, Tulio de Oliveira, Ana Maria Bispo de Filippis, Rivaldo Venâncio da Cunha, Kleber Giovanni Luz, Marta Giovanetti, Luiz Carlos Junior Alcantara
{"title":"Chikungunya virus ECSA lineage reintroduction in the northeasternmost region of Brazil.","authors":"Joilson Xavier,&nbsp;Vagner Fonseca,&nbsp;Joao Felipe Bezerra,&nbsp;Manoella do Monte Alves,&nbsp;Maria Angélica Mares-Guia,&nbsp;Ingra Morales Claro,&nbsp;Ronaldo de Jesus,&nbsp;Talita Adelino,&nbsp;Emerson Araújo,&nbsp;Karina Ribeiro Leite Jardim Cavalcante,&nbsp;Stephane Tosta,&nbsp;Themis Rocha de Souza,&nbsp;Flavia Emanuelle Moreira da Cruz,&nbsp;Allison de Araújo Fabri,&nbsp;Elaine Cristina de Oliveira,&nbsp;Noely Fabiana Oliveira de Moura,&nbsp;Rodrigo Fabiano do Carmo Said,&nbsp;Carlos Frederico Campelo de Albuquerque,&nbsp;Vasco Azevedo,&nbsp;Tulio de Oliveira,&nbsp;Ana Maria Bispo de Filippis,&nbsp;Rivaldo Venâncio da Cunha,&nbsp;Kleber Giovanni Luz,&nbsp;Marta Giovanetti,&nbsp;Luiz Carlos Junior Alcantara","doi":"10.1016/j.ijid.2021.01.026","DOIUrl":"https://doi.org/10.1016/j.ijid.2021.01.026","url":null,"abstract":"<p><p>The Northeast region of Brazil registered the second-highest incidence proportion of Chikungunya fever in 2019. In that year, an outbreak consisting of patients presenting with febrile disease associated with joint pain was reported by the public primary health care service in the city of Natal, in the state of Rio Grande do Norte, in March 2019. At first, the aetiological agent of the disease was undetermined. Since much is still unknown about chikungunya virus' (CHIKV) genomic diversity and evolutionary history in this northeasternmost state, we used a combination of portable whole-genome sequencing, molecular clock, and epidemiological analyses that revealed the reintroduction of the CHIKV East-Central-South-African (ECSA) lineage into Rio Grande do Norte. We estimated that the CHIKV ECSA lineage was first introduced into Rio Grande do Norte in early June 2014, while the 2019 outbreak clade diverged around April 2018, during a period of increased Chikungunya incidence in the Southeast region, which might have acted as a source of virus dispersion towards the Northeast region. Together, these results confirm that the ECSA lineage continues to spread across the country through interregional importation events, likely mediated by human mobility.</p>","PeriodicalId":505767,"journal":{"name":"International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases","volume":" ","pages":"120-123"},"PeriodicalIF":8.4,"publicationDate":"2021-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.ijid.2021.01.026","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38844226","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 11
Emergence and spread of different ctxB alleles of Vibrio cholerae O1 in Odisha, India. O1霍乱弧菌不同ctxB等位基因在印度奥里萨邦的出现和传播
IF 8.4
Bibhuti Bhusan Pal, Ashish Kumar Nayak, Smruti Ranjan Nayak
{"title":"Emergence and spread of different ctxB alleles of Vibrio cholerae O1 in Odisha, India.","authors":"Bibhuti Bhusan Pal,&nbsp;Ashish Kumar Nayak,&nbsp;Smruti Ranjan Nayak","doi":"10.1016/j.ijid.2021.03.042","DOIUrl":"https://doi.org/10.1016/j.ijid.2021.03.042","url":null,"abstract":"<p><p>This study reports variants of the ctxB allele of Vibrio cholerae O1 isolated between 1995 and 2019 in Odisha, India. ctxB1 genotypes dominated from 1995 to 2016. The Haitian variant and El Tor ctxB3 genotypes of V. cholerae O1 emerged in 1999, and were most common in 2018-2019 and 2005-2011, respectively. The ctxB7 genotype of the Haitian variant of V. cholerae O1 was quiescent from 2000 to 2006, but further spread was noted from 2007 to 2019.</p>","PeriodicalId":505767,"journal":{"name":"International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases","volume":" ","pages":"730-732"},"PeriodicalIF":8.4,"publicationDate":"2021-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.ijid.2021.03.042","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25496449","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Atypical hand, foot and mouth disease with eczematiform presentation in an adult patient. 非典型手足口病,成人患者湿疹样表现。
IF 8.4
Antonios Kritikos
{"title":"Atypical hand, foot and mouth disease with eczematiform presentation in an adult patient.","authors":"Antonios Kritikos","doi":"10.1016/j.ijid.2021.02.075","DOIUrl":"https://doi.org/10.1016/j.ijid.2021.02.075","url":null,"abstract":"","PeriodicalId":505767,"journal":{"name":"International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases","volume":" ","pages":"397-398"},"PeriodicalIF":8.4,"publicationDate":"2021-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.ijid.2021.02.075","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25399542","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Peripheral neuropathy due to neuroborreliosis: Insensitivity for CXCL13 as early diagnostic marker. 神经螺旋体病引起的周围神经病变:CXCL13作为早期诊断标志物不敏感。
IF 8.4
Kristina Gubanova, Julia Lang, Juliane Latzko, Bianka Novotna, Julian Perneczky, Stefan Pingitzer, Petra Purer, Bianca Wuchty, Christoph Waiß, Johann Sellner
{"title":"Peripheral neuropathy due to neuroborreliosis: Insensitivity for CXCL13 as early diagnostic marker.","authors":"Kristina Gubanova,&nbsp;Julia Lang,&nbsp;Juliane Latzko,&nbsp;Bianka Novotna,&nbsp;Julian Perneczky,&nbsp;Stefan Pingitzer,&nbsp;Petra Purer,&nbsp;Bianca Wuchty,&nbsp;Christoph Waiß,&nbsp;Johann Sellner","doi":"10.1016/j.ijid.2021.02.050","DOIUrl":"https://doi.org/10.1016/j.ijid.2021.02.050","url":null,"abstract":"<p><p>The case of a 69-year-old woman with peripheral neuropathy caused by Lyme neuroborreliosis (LNB) in an endemic region in Eastern Austria is reported. The patient had noticed transient numbness of her left leg. On initial examination, she had patchy sensory disturbances of the left lower leg, but ancillary examinations of nerve conduction and cerebrospinal fluid (CSF), including the B-cell chemokine CXCL13, were normal. A re-tap performed 54 days later, following clinical progression with foot drop, widespread lower leg paresthesia, and pain, revealed an increased cell count, autochthonous IgM production, synthesis of Borrelia-specific IgM, and elevated CXCL13. Neurophysiological examinations disclosed an incomplete conduction block, mixed axonal and demyelinating sensorimotor neuropathy, and subacute neurogenic damage of muscles innervated by the peroneal nerve. This case study presents rare evidence of very early diagnostic findings in peripheral neuropathy caused by LNB. These are characterized by insensitivity of CXCL13 in CSF to aid earlier diagnosis and the development of an intrathecal immune response against Borrelia at a later stage. These findings reinforce the need for a re-tap to confirm the diagnosis and facilitate appropriate treatment in this rare manifestation of LNB.</p>","PeriodicalId":505767,"journal":{"name":"International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases","volume":" ","pages":"460-462"},"PeriodicalIF":8.4,"publicationDate":"2021-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.ijid.2021.02.050","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25462561","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Abdominal paragonimiasis after consumption of wild boar meat. 食用野猪肉后得腹部吸虫病。
IF 8.4
Shinya Nakashima, Ichiro Takajo, Haruhiko Maruyama, Eiji Nagayasu
{"title":"Abdominal paragonimiasis after consumption of wild boar meat.","authors":"Shinya Nakashima,&nbsp;Ichiro Takajo,&nbsp;Haruhiko Maruyama,&nbsp;Eiji Nagayasu","doi":"10.1016/j.ijid.2021.02.012","DOIUrl":"https://doi.org/10.1016/j.ijid.2021.02.012","url":null,"abstract":"","PeriodicalId":505767,"journal":{"name":"International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases","volume":" ","pages":"40-41"},"PeriodicalIF":8.4,"publicationDate":"2021-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.ijid.2021.02.012","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25362801","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Congenital Zika syndrome: Growth, clinical, and motor development outcomes up to 36 months of age and differences according to microcephaly at birth. 先天性寨卡综合征:36个月前的生长、临床和运动发育结果以及出生时小头畸形的差异
IF 8.4
Tamires Barradas Cavalcante, Marizélia Rodrigues Costa Ribeiro, Patrícia da Silva Sousa, Elaine de Paula Fiod Costa, Maria Teresa Seabra Soares de Brito E Alves, Vanda Maria Ferreira Simões, Rosângela Fernandes Lucena Batista, Eliana Harumi Morioka Takahasi, Gláucio Andrade Amaral, Ricardo Khouri, Maria Dos Remédios Freitas Carvalho Branco, Ana Karolina Torres Mendes, Luciana Cavalcante Costa, Marcos Adriano Garcia Campos, Antônio Augusto Moura da Silva
{"title":"Congenital Zika syndrome: Growth, clinical, and motor development outcomes up to 36 months of age and differences according to microcephaly at birth.","authors":"Tamires Barradas Cavalcante,&nbsp;Marizélia Rodrigues Costa Ribeiro,&nbsp;Patrícia da Silva Sousa,&nbsp;Elaine de Paula Fiod Costa,&nbsp;Maria Teresa Seabra Soares de Brito E Alves,&nbsp;Vanda Maria Ferreira Simões,&nbsp;Rosângela Fernandes Lucena Batista,&nbsp;Eliana Harumi Morioka Takahasi,&nbsp;Gláucio Andrade Amaral,&nbsp;Ricardo Khouri,&nbsp;Maria Dos Remédios Freitas Carvalho Branco,&nbsp;Ana Karolina Torres Mendes,&nbsp;Luciana Cavalcante Costa,&nbsp;Marcos Adriano Garcia Campos,&nbsp;Antônio Augusto Moura da Silva","doi":"10.1016/j.ijid.2021.02.072","DOIUrl":"https://doi.org/10.1016/j.ijid.2021.02.072","url":null,"abstract":"<p><strong>Background: </strong>Little is known regarding the developmental consequences of congenital Zika syndrome (CZS) without microcephaly at birth. Most previously published clinical series were descriptive and they had small sample sizes.</p><p><strong>Study design: </strong>We conducted a cohort study to compare the growth, clinical, and motor development outcomes for 110 children with CZS born with and without microcephaly up to their third birthday. Ninety-three had their head circumference (HC) at birth abstracted and they did not have hypertensive hydrocephalus at birth, where 61 were born with microcephaly and 32 without.</p><p><strong>Results: </strong>The HC z-scores decreased steeply from birth to six months of age, i.e., from -3.77 to -6.39 among those with microcephaly at birth and from -1.03 to -3.84 among those without. Thus, at 6 months of age, the mean HC z-scores for children born without microcephaly were nearly the same as those for children born with microcephaly. Children born without microcephaly were less likely to have brain damage, ophthalmic abnormalities, and drug-resistant epilepsy, but the differences in many conditions were not statistically significant.</p><p><strong>Conclusions: </strong>Children born without microcephaly were only slightly less likely to present severe neurologic impairment and to develop postnatal-onset microcephaly, and some of the original differences between the groups tended to dissipate with age.</p>","PeriodicalId":505767,"journal":{"name":"International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases","volume":" ","pages":"399-408"},"PeriodicalIF":8.4,"publicationDate":"2021-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.ijid.2021.02.072","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25387608","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 12
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