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Relationship Between Apoptosis Induction in Cancer Cells and the Amount of Electrical Stimulation on Frequency Analysis of Nanosecond Pulsed Electric Field
IF 0.4 4区 工程技术
Electrical Engineering in Japan Pub Date : 2025-01-06 DOI: 10.1002/eej.23493
Yuto Ninagawa, Ren Sugiura, Eiko Kato, Ippei Yagi, Kohki Nagata, Hidehiko Yamaoka, Kosuke Tachibana, Akinori Oda, Satoshi Uchida
{"title":"Relationship Between Apoptosis Induction in Cancer Cells and the Amount of Electrical Stimulation on Frequency Analysis of Nanosecond Pulsed Electric Field","authors":"Yuto Ninagawa,&nbsp;Ren Sugiura,&nbsp;Eiko Kato,&nbsp;Ippei Yagi,&nbsp;Kohki Nagata,&nbsp;Hidehiko Yamaoka,&nbsp;Kosuke Tachibana,&nbsp;Akinori Oda,&nbsp;Satoshi Uchida","doi":"10.1002/eej.23493","DOIUrl":"https://doi.org/10.1002/eej.23493","url":null,"abstract":"<div>\u0000 \u0000 <p>Nanosecond pulse electric field (nsPEF) therapy has attracted attention in recent years as a noninvasive cancer treatment with minimal side effects. However, the relationship between the electrical stress induced in cells by the external electric field and the biological response has not been fully investigated quantitatively. We investigated the effects of nsPEF therapy on cancer cells using microgap electrodes under low-voltage conditions. We developed an equivalent circuit model using intracellular components to determine the amount of stimulation of cellular components and performed frequency analysis of nsPEF. nsPEF applied to Jurkat cells activated caspase-3 and induced apoptosis at shorter pulse widths. nsPEF induced biological responses and apoptosis in cancer cells. The relationship between the biological response induced by nsPEF and the amount of electrical stimulation was investigated by comparing the experimental results with frequency analysis. Using quantitative values for each cellular element, the relationship between the biological response and the amount of electrical stimulation can be integrated.</p>\u0000 </div>","PeriodicalId":50550,"journal":{"name":"Electrical Engineering in Japan","volume":"218 1","pages":""},"PeriodicalIF":0.4,"publicationDate":"2025-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143564795","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Development and Validation of Estimation of Breakdown Voltage of Stator Windings of Generator From Partial Discharge Magnitude
IF 0.4 4区 工程技术
Electrical Engineering in Japan Pub Date : 2025-01-06 DOI: 10.1002/eej.23489
Shin Nakamura, Masaki Kanegami, Takashi Kuraishi, Satoru Miyazaki
{"title":"Development and Validation of Estimation of Breakdown Voltage of Stator Windings of Generator From Partial Discharge Magnitude","authors":"Shin Nakamura,&nbsp;Masaki Kanegami,&nbsp;Takashi Kuraishi,&nbsp;Satoru Miyazaki","doi":"10.1002/eej.23489","DOIUrl":"https://doi.org/10.1002/eej.23489","url":null,"abstract":"<div>\u0000 \u0000 <p>For the insulation diagnosis of stator windings of generators, sampling surveys are conducted on the coils to estimate the dielectric strength of the stator winding. Previous research has relied on inferring the breakdown voltage of the stator winding from the value 3σ away from the mean value of the breakdown voltage of the coil. However, this conventional method exhibits a significant estimation error when the sample size is small. Therefore, we propose a method for estimating the breakdown voltage of the stator winding based on the maximum value of the partial discharge magnitude and the minimum value of the breakdown voltage of the sample coil. We verify this method by Monte Carlo simulation assuming a sampling survey of coils.</p>\u0000 </div>","PeriodicalId":50550,"journal":{"name":"Electrical Engineering in Japan","volume":"218 1","pages":""},"PeriodicalIF":0.4,"publicationDate":"2025-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143564798","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Oxidation of Iodine Using Ozone by Plasma Emitted in Aqueous Solution
IF 0.4 4区 工程技术
Electrical Engineering in Japan Pub Date : 2025-01-04 DOI: 10.1002/eej.23498
Kouta Iwai, Tomohiko Tsuruoka, Satoshi Asakura, Hiroyuki Kawamoto, Katsumasa Yoshida, Nobuo Satoh
{"title":"Oxidation of Iodine Using Ozone by Plasma Emitted in Aqueous Solution","authors":"Kouta Iwai,&nbsp;Tomohiko Tsuruoka,&nbsp;Satoshi Asakura,&nbsp;Hiroyuki Kawamoto,&nbsp;Katsumasa Yoshida,&nbsp;Nobuo Satoh","doi":"10.1002/eej.23498","DOIUrl":"https://doi.org/10.1002/eej.23498","url":null,"abstract":"<div>\u0000 \u0000 <p>In this study, we explore an innovative method for iodine oxidation utilizing ozone generated through plasma phenomena.  Our investigation centers on understanding the amount of oxidation by ozone in an Aqueous Solution, quantifying it with that of an aqueous potassium iodide solution, thereby assessing the viability of our proposed technique. While certain practical considerations warrant attention as we strive for real-world implementation, we posit that elevating ozone production by expanding the electrode discharge area holds promise for further optimization and subsequent cost minimization.</p>\u0000 </div>","PeriodicalId":50550,"journal":{"name":"Electrical Engineering in Japan","volume":"218 1","pages":""},"PeriodicalIF":0.4,"publicationDate":"2025-01-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143564594","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Silver-Nanowire/Graphene Stacked Transparent Electrodes and Its Application to Flexible Thin Film Photovoltaic Device
IF 0.4 4区 工程技术
Electrical Engineering in Japan Pub Date : 2025-01-04 DOI: 10.1002/eej.23504
Miho Akasaka, Masahiko Noguchi, Taizo Kobayashi
{"title":"Silver-Nanowire/Graphene Stacked Transparent Electrodes and Its Application to Flexible Thin Film Photovoltaic Device","authors":"Miho Akasaka,&nbsp;Masahiko Noguchi,&nbsp;Taizo Kobayashi","doi":"10.1002/eej.23504","DOIUrl":"https://doi.org/10.1002/eej.23504","url":null,"abstract":"<div>\u0000 \u0000 <p>In this study, silver nanowire covered with graphene (AgNW/Graphene) transparent conducting electrodes (TCE) were developed as bendable TCE instead of conventionally used indium tin oxide (ITO) for flexible photovoltaic applications. CVD-grown graphene films were transferred from a Cu foil onto a spin-coated AgNW TCE. AgNW/Graphene TCE exhibited lower electrical resistance than 10 Ω and high optical transmission of approximately 80% at visible wavelengths before and after bending of 20 cycles at a radius of 15 mm. Thermal tolerance of AgNW was drastically improved by protecting silver nanowires with graphene from oxidation at the 300°C air annealing test. ZnMgO/Se thin film photovoltaic devices with AgNW/graphene were successfully demonstrated by insertion of a sol-gel ZnO buffer layer in order to protect AgNW/graphene from sputtering bombardment.</p>\u0000 </div>","PeriodicalId":50550,"journal":{"name":"Electrical Engineering in Japan","volume":"218 1","pages":""},"PeriodicalIF":0.4,"publicationDate":"2025-01-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143565183","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Lyapunov-Based Passive Control Method for DC Input Admittance of IPM Motor Drive System
IF 0.4 4区 工程技术
Electrical Engineering in Japan Pub Date : 2025-01-04 DOI: 10.1002/eej.23486
Takaya Karino, Toshiji Kato, Kaoru Inoue, Koki Yamada
{"title":"Lyapunov-Based Passive Control Method for DC Input Admittance of IPM Motor Drive System","authors":"Takaya Karino,&nbsp;Toshiji Kato,&nbsp;Kaoru Inoue,&nbsp;Koki Yamada","doi":"10.1002/eej.23486","DOIUrl":"https://doi.org/10.1002/eej.23486","url":null,"abstract":"<div>\u0000 \u0000 <p>It is important to drive an IPM motor system stably. However, unstable oscillations at the DC input have been reported. According to the impedance method, stability is assured when the input admittance of the drive system is passive or resistive. In this paper, we propose a passive admittance control method utilizing a Lyapunov-based method. The control principle is first described and then a design example is detailed. It is shown that the proposed method achieves passive frequency characteristics for the input admittance. Its stable operation behaviors were investigated both by simulation and experimentally.</p>\u0000 </div>","PeriodicalId":50550,"journal":{"name":"Electrical Engineering in Japan","volume":"218 1","pages":""},"PeriodicalIF":0.4,"publicationDate":"2025-01-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143564592","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Short-Term Ensemble Insolation Forecasting Method Using Parallelized NE
IF 0.4 4区 工程技术
Electrical Engineering in Japan Pub Date : 2025-01-04 DOI: 10.1002/eej.23487
Shoji Kawasaki, Koshi Ishibe
{"title":"Short-Term Ensemble Insolation Forecasting Method Using Parallelized NE","authors":"Shoji Kawasaki,&nbsp;Koshi Ishibe","doi":"10.1002/eej.23487","DOIUrl":"https://doi.org/10.1002/eej.23487","url":null,"abstract":"<div>\u0000 \u0000 <p>In this paper, the authors propose an ensemble forecasting method using multiple individuals for short-time-ahead (1 h ahead) insolation forecasting by using neuroevolution (NE), in which a genetic algorithm is applied to the learning algorithm of a neural network for insolation. Although the method improves the accuracy compared to a single forecast, NE has a problem that the training time is long. In order to solve this problem, the authors propose a parallelization method of GPU processing for short-time-ahead forecasting and try to solve the problem by parallelizing the GPU.</p>\u0000 </div>","PeriodicalId":50550,"journal":{"name":"Electrical Engineering in Japan","volume":"218 1","pages":""},"PeriodicalIF":0.4,"publicationDate":"2025-01-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143564591","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Charging and Discharging Schedule Optimization Method Considering Renewable Energy and Distribution System for Electric Buses
IF 0.4 4区 工程技术
Electrical Engineering in Japan Pub Date : 2025-01-04 DOI: 10.1002/eej.23497
Natsuno Kato, Tsunayoshi Ishii, Yutaka Iino, Yasuhiro Hayashi, Shingo Uchiyama, Kohei Oishi, Kenjiro Mori
{"title":"Charging and Discharging Schedule Optimization Method Considering Renewable Energy and Distribution System for Electric Buses","authors":"Natsuno Kato,&nbsp;Tsunayoshi Ishii,&nbsp;Yutaka Iino,&nbsp;Yasuhiro Hayashi,&nbsp;Shingo Uchiyama,&nbsp;Kohei Oishi,&nbsp;Kenjiro Mori","doi":"10.1002/eej.23497","DOIUrl":"https://doi.org/10.1002/eej.23497","url":null,"abstract":"<div>\u0000 \u0000 <p>Electric buses are introduced toward achieving carbon neutrality by 2050, and there is a movement to utilize their storage batteries. On the other hand, the electric power system, where distributed energy resources are rapidly spreading, is becoming increasingly complex, and the impact of charging by electric buses on power system is an issue. In this study, we propose an optimization method for electric bus charge/discharge schedule that considers sector coupling between transportation system and power system. Then, we evaluate the effectiveness of the proposed method from the viewpoints of both the distribution system operator and the electric bus operator by performing power flow calculations using a distribution system model. The results show that the proposed method can contribute to power demand shifting and smoothing power flow in distribution network by charging and discharging, and that multiple evaluation indices, for example, peak-cutting of power flow, line occupation rate, distribution loss, reverse power flow utilization rate, renewable energy rate and CO<sub>2</sub> emissions, are improved compared to the conventional charging scheduling method.</p>\u0000 </div>","PeriodicalId":50550,"journal":{"name":"Electrical Engineering in Japan","volume":"218 1","pages":""},"PeriodicalIF":0.4,"publicationDate":"2025-01-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143564593","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Bridgeless Power Factor Correction Flyback Rectifier Using a Novel Integrated Transformer
IF 0.4 4区 工程技术
Electrical Engineering in Japan Pub Date : 2025-01-03 DOI: 10.1002/eej.23485
Haruki Hirasawa, Sihoon Choi, Yu Yonezawa, Jun Imaoka, Masayoshi Yamamoto
{"title":"Bridgeless Power Factor Correction Flyback Rectifier Using a Novel Integrated Transformer","authors":"Haruki Hirasawa,&nbsp;Sihoon Choi,&nbsp;Yu Yonezawa,&nbsp;Jun Imaoka,&nbsp;Masayoshi Yamamoto","doi":"10.1002/eej.23485","DOIUrl":"https://doi.org/10.1002/eej.23485","url":null,"abstract":"<div>\u0000 \u0000 <p>This study proposes a novel integrated transformer structure with simple circuit configuration and miniaturized magnetic components. In a bridgeless flyback rectifier, two flyback converters operate corresponding to the polarity of the AC input, requiring two transformers. This paper proposes a novel winding structure that realizes zero coupling co-efficient between two sets of windings. This enables the integration of two transformers into a single transformer, preventing their flyback operations from interfering with each other. The integrated transformer has approximately 16% lower volume compared to that of conventional transformers. The proposed integrated transformer was built, evaluated, and verified by designing a 75 W-bridgeless flyback rectifier with 100 kHz switching frequency.</p>\u0000 </div>","PeriodicalId":50550,"journal":{"name":"Electrical Engineering in Japan","volume":"218 1","pages":""},"PeriodicalIF":0.4,"publicationDate":"2025-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143564781","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Compartmentalization Device of Microenvironment for Analyzing iPSCs Differentiation
IF 0.4 4区 工程技术
Electrical Engineering in Japan Pub Date : 2025-01-03 DOI: 10.1002/eej.23503
Daiki Fukai, Taro Toyoda, Hidekuni Takao, Fusao Shimokawa, Kyohei Terao
{"title":"Compartmentalization Device of Microenvironment for Analyzing iPSCs Differentiation","authors":"Daiki Fukai,&nbsp;Taro Toyoda,&nbsp;Hidekuni Takao,&nbsp;Fusao Shimokawa,&nbsp;Kyohei Terao","doi":"10.1002/eej.23503","DOIUrl":"https://doi.org/10.1002/eej.23503","url":null,"abstract":"<div>\u0000 \u0000 <p>This paper reports on a microdevice for compartmentalizing the solution microenvironment that can fractionate the space surrounding spheroids during the culture and differentiation processes, with the aim of verifying the effects of cell–cell interactions in the solution microenvironment on iPS cell differentiation. In this paper, we demonstrated that spheroids of iPS cells were successfully formed on the device and fractionated their microenvironment by a detachable compartmentalization frame (DCF) formed by 3D printing technology.</p>\u0000 </div>","PeriodicalId":50550,"journal":{"name":"Electrical Engineering in Japan","volume":"218 1","pages":""},"PeriodicalIF":0.4,"publicationDate":"2025-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143564780","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Noninvasive Biofluorometric Sensing and Imaging Analysis of Blood VOCs for Novel Wearable Sensor
IF 0.4 4区 工程技术
Electrical Engineering in Japan Pub Date : 2025-01-02 DOI: 10.1002/eej.23490
Kohji Mitsubayashi
{"title":"Noninvasive Biofluorometric Sensing and Imaging Analysis of Blood VOCs for Novel Wearable Sensor","authors":"Kohji Mitsubayashi","doi":"10.1002/eej.23490","DOIUrl":"https://doi.org/10.1002/eej.23490","url":null,"abstract":"<div>\u0000 \u0000 <p>Blood contains volatile biomarkers related to diseases and metabolism. We developed a biofluorometric gas sensor that measures acetone with high sensitivity and confirmed its significance in lipid metabolism and diabetes when applied to breath measurement. Furthermore, regarding transcutaneous gases that permeate through the skin from blood, a biofluorometric gas-imaging system for ethanol vapor as the target chemical was developed and analyzed the secretion dynamics of transcutaneous gases at each skin site, thus showing the stable release of blood-derived volatile markers from the ear canal. Based on the results, we have developed a headphone-type gas sensor and succeeded in continuous and stable transcutaneous gas measurement, thus indicating the future potential of a novel wearable biosensor for blood VOCs.</p>\u0000 </div>","PeriodicalId":50550,"journal":{"name":"Electrical Engineering in Japan","volume":"218 1","pages":""},"PeriodicalIF":0.4,"publicationDate":"2025-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143565176","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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