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Effects of nanosecond pulsed electric fields application on cancer cell and combination of anticancer drug 纳秒脉冲电场对肿瘤细胞及抗癌药物联合的影响
IF 0.4 4区 工程技术
Electrical Engineering in Japan Pub Date : 2022-03-02 DOI: 10.1002/eej.23376
Soichiro Enomoto, Daisuke Konishi, Yoshihiro Uto, Naoyuki Shimomura
{"title":"Effects of nanosecond pulsed electric fields application on cancer cell and combination of anticancer drug","authors":"Soichiro Enomoto,&nbsp;Daisuke Konishi,&nbsp;Yoshihiro Uto,&nbsp;Naoyuki Shimomura","doi":"10.1002/eej.23376","DOIUrl":"10.1002/eej.23376","url":null,"abstract":"<p>With the goal of establishing a new cancer treatment method using nanosecond pulsed electric fields (nsPEFs), we investigated the effect of applying nsPEFs and anticancer drugs (adriamycin, ADM) to cancer cells. The surviving fraction of cancer cells was significantly reduced by nsPEFs application compared to the control. Compared to nsPEFs alone and ADM administration alone, a significant decrease of the surviving fraction was observed in combination of nsPEFs application and ADM administration. In addition, multiplying value of surviving fractions of nsPEFs application and ADM administration was calculated as a pseudo-combination effect. The surviving fractions of the experimental combinational results of nsPEFs and ADM were lower than the pseudo-combination results. Therefore, the synergistic effect of combination of nsPEFs and ADM was confirmed. Furthermore, the surviving fraction of ADM administration after nsPEFs application was significantly lower than that of ADM administration on 24 h before nsPEFs application. ADM action on cells would be effective owing to nanopores were formed by applying nsPEFs. It was confirmed that ADM and nsPEF induced apoptosis of cells from apoptosis and necrosis test using FACS.</p>","PeriodicalId":50550,"journal":{"name":"Electrical Engineering in Japan","volume":"215 2","pages":""},"PeriodicalIF":0.4,"publicationDate":"2022-03-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77933853","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Development of dynamic wireless power transfer system for vehicle logistics robot 车载物流机器人动态无线电力传输系统的研制
IF 0.4 4区 工程技术
Electrical Engineering in Japan Pub Date : 2022-03-02 DOI: 10.1002/eej.23381
Osamu Shimizu, Kazuyoshi Hanabusa, Kota Arasaki, Daisuke Gunji, Yuto Sakai, Hiromori Ikeda, Fuminori Matsuoka
{"title":"Development of dynamic wireless power transfer system for vehicle logistics robot","authors":"Osamu Shimizu,&nbsp;Kazuyoshi Hanabusa,&nbsp;Kota Arasaki,&nbsp;Daisuke Gunji,&nbsp;Yuto Sakai,&nbsp;Hiromori Ikeda,&nbsp;Fuminori Matsuoka","doi":"10.1002/eej.23381","DOIUrl":"10.1002/eej.23381","url":null,"abstract":"<p>Laborsaving is a major issue in production. In an automotive production line, a yard that is used as a temporary storage for vehicles before shipping. The vehicle-loading robot that operates autonomously has been proposed to automate the alignment of vehicles in the yard instead of human driving. In this study, the dynamic wireless power transfer (DWPT) system that includes the structure of the roadside for the vehicle-loaded robot is proposed. It is proven that the transmitter coil has enough durability for the load of the robot weight using simulation and actual measurement. It is also shown that the reinforcement bars of the road structure cause considerable eddy current loss even with stainless steel. This is similar to loss by coil resistance. This system achieves a 1.8 kW DWPT with an automated coil detection system and a frequency control system, under factory conditions.</p>","PeriodicalId":50550,"journal":{"name":"Electrical Engineering in Japan","volume":"215 2","pages":""},"PeriodicalIF":0.4,"publicationDate":"2022-03-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81920569","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Parameter determination for reducing ESS capacity in PV power smoothing control using spline function 利用样条函数降低光伏功率平滑控制中ESS容量的参数确定
IF 0.4 4区 工程技术
Electrical Engineering in Japan Pub Date : 2022-03-01 DOI: 10.1002/eej.23367
Akiko Takahashi, Tatsuya Kajitani, Shigeyuki Funabiki
{"title":"Parameter determination for reducing ESS capacity in PV power smoothing control using spline function","authors":"Akiko Takahashi,&nbsp;Tatsuya Kajitani,&nbsp;Shigeyuki Funabiki","doi":"10.1002/eej.23367","DOIUrl":"10.1002/eej.23367","url":null,"abstract":"<p>This paper comprehensively evaluates the PV power smoothing control method using the spline function. As a result of the verification, it is shown that the ESS capacity can be reduced while maintaining the smoothing effect by PV power smoothing control with energy control and limiting fluctuation rate control. Based on the charging/discharging power of the ESS and the operating conditions of the ESS, the section time that achieves both improvement of the smoothing effect and reduction of the ESS capacity is determined to be 1500 s. Then, the rated capacity of the ESS for a rated power of 1.75MW PV system is 1128 kWh. This is 49.6% of the rated capacity of the ESS, which is required in the PV power smoothing control method with fluctuation rate control. As a result of comparing the proposed method and the moving average method, the proposed method improved the smoothing effect by 49.8% compared to the moving average method.</p>","PeriodicalId":50550,"journal":{"name":"Electrical Engineering in Japan","volume":"215 2","pages":""},"PeriodicalIF":0.4,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89154095","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Waveform conversion and validation of transient magnetic field due to ESD using equivalent circuit of magnetic near‐field probe 利用磁性近场探头等效电路进行ESD瞬态磁场波形转换与验证
IF 0.4 4区 工程技术
Electrical Engineering in Japan Pub Date : 2022-02-28 DOI: 10.1002/eej.23371
Jianqing Wang, K. Kawamata, S. Ishigami, Takeshi Ishida, O. Fujiwara
{"title":"Waveform conversion and validation of transient magnetic field due to ESD using equivalent circuit of magnetic near‐field probe","authors":"Jianqing Wang, K. Kawamata, S. Ishigami, Takeshi Ishida, O. Fujiwara","doi":"10.1002/eej.23371","DOIUrl":"https://doi.org/10.1002/eej.23371","url":null,"abstract":"With a 6 GHz band high resolution magnetic near‐field probe (XF‐R 3‐1) produced by Langer, the transient magnetic fields due to collision ESDs (electrostatic discharges) between metal balls at a charging voltage of 600 V were measured near the spark point to investigate a dipole radiation mechanism. In this study, as an object of considering the measured magnetic field waveforms, two different equivalent circuits of the magnetic near‐field probe are derived based on the probe response waveform observed by a TDR (time domain reflectometer) with a 10 ps rise‐time pulse and the probe reflection coefficient measured with a 26 GHz network analyzer. Waveform conversion formulae from the probe output voltage to the magnetic field are given. The validity of the conversion methods is verified by comparing the measured conversion waveforms and their frequency spectra in addition to the converted spectra by the Langer field correction curve with the calculated waveforms of the transient magnetic far‐fields from a dipole model consisting of image charge pairs and the Rompe‐Weizel spark resistance formula. The probe conversion formulae presented here are valid within the frequency range of the 6 GHz probe band, however, beyond the band the resonance peaks at multiple frequencies over 8 GHz appear on the spectra, which causes damping oscillations peculiar to the probe with multiple frequencies to the time domain waveform.","PeriodicalId":50550,"journal":{"name":"Electrical Engineering in Japan","volume":"19 1","pages":""},"PeriodicalIF":0.4,"publicationDate":"2022-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78114614","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Nondistractive extraction of intracellular molecules from yeast using PEF‐assisted autolysis 利用PEF辅助自溶法无干扰提取酵母胞内分子
IF 0.4 4区 工程技术
Electrical Engineering in Japan Pub Date : 2022-02-22 DOI: 10.1002/eej.23372
Shuji Okamoto, Yoji Murakami, Gen Urabe, S. Katsuki
{"title":"Nondistractive extraction of intracellular molecules from yeast using PEF‐assisted autolysis","authors":"Shuji Okamoto, Yoji Murakami, Gen Urabe, S. Katsuki","doi":"10.1002/eej.23372","DOIUrl":"https://doi.org/10.1002/eej.23372","url":null,"abstract":"This paper discusses the possibility of nondestructive extraction of intracellular proteins of yeast (Saccharomyces cerevisiae) by means of pulsed electric fields (PEFs) combined with autolysis. First, the effects of PEFs (20 kV/cm, 600 ns) on yeast and the subsequent cell wall collapse phenomenon were studied by morphological observation of fluorescence staining. Morphological observation shows that the PEFs increase the permeability of the cell membrane and also disrupt the intracellular vacuoles, whereas the cell wall morphology remains unchanged. However, the cell wall was collapse during the postPEF incubation. Next, the amount of extracted protein was evaluated by using the BCA assay. The amount of extracted protein in the PEF treated suspension was only a little, whereas the additional incubation promotes the extraction. Lastly, the size of the extracted proteins was investigated by using both Native‐PAGE and SDS‐PAGE. The PEF‐treated and incubated suspension contains the large protein over 250 kDa.","PeriodicalId":50550,"journal":{"name":"Electrical Engineering in Japan","volume":"13 1","pages":""},"PeriodicalIF":0.4,"publicationDate":"2022-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74156052","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Improvement of low‐speed sensorless control with multi‐layer neural network 多层神经网络对低速无传感器控制的改进
IF 0.4 4区 工程技术
Electrical Engineering in Japan Pub Date : 2022-02-22 DOI: 10.1002/eej.23369
Sari Maekawa, A. Tanaka
{"title":"Improvement of low‐speed sensorless control with multi‐layer neural network","authors":"Sari Maekawa, A. Tanaka","doi":"10.1002/eej.23369","DOIUrl":"https://doi.org/10.1002/eej.23369","url":null,"abstract":"In recent years, there has been an increasing demand for position sensorless control in Permanent Magnet Synchronous Motor (PMSM) drives, and various methods have been studied. Switching noise is a problem in the low‐speed sensorless control method that uses the current slope during PWM. Furthermore, another problem is that the inductance does not appear in a sinusoidal distribution owing to magnetic saturation. In this paper, we improve the sensorless control method that estimates the position from the current slope during PWM, which is greatly affected by switching. Additionally, we build a multi‐layer neural network (NN) that directly estimates the position signals by learning a large amount of current data, and verify the driving results in the low‐speed range when the learned NN is incorporated into real‐time control.","PeriodicalId":50550,"journal":{"name":"Electrical Engineering in Japan","volume":"60 1","pages":""},"PeriodicalIF":0.4,"publicationDate":"2022-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76205466","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Fabrication of heater‐integrated MEMS tactile sensor for evaluation of warm and cold sensation by touching glass 加热集成MEMS触觉传感器的制造，用于评估触摸玻璃的冷热感觉
IF 0.4 4区 工程技术
Electrical Engineering in Japan Pub Date : 2022-02-21 DOI: 10.1002/eej.23370
Naotaka Onda, Takaaki Kozuka, Takashi Abe, M. Isshiki, Satoru Tomeno, Masayuki Sohgawa
{"title":"Fabrication of heater‐integrated MEMS tactile sensor for evaluation of warm and cold sensation by touching glass","authors":"Naotaka Onda, Takaaki Kozuka, Takashi Abe, M. Isshiki, Satoru Tomeno, Masayuki Sohgawa","doi":"10.1002/eej.23370","DOIUrl":"https://doi.org/10.1002/eej.23370","url":null,"abstract":"The paper addresses fabrication and characterization of a MEMS tactile sensor sensitive to force and temperature with an on‐chip heater and a contact part of thermally conductive elastomer. The temperature response of this sensor due to heat transfer when it was in contact with the glass plate was measured. As a result, it is demonstrated that fabricated sensor can detect thermally difference due to differences in the surface treatment of the glass.","PeriodicalId":50550,"journal":{"name":"Electrical Engineering in Japan","volume":"100 1","pages":""},"PeriodicalIF":0.4,"publicationDate":"2022-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73654871","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Development of a numerical model for metal vapor dynamics in low pressure arcs based on moving particle semi‐implicit method and influence of shield wall radius on vapor behavior 基于移动粒子半隐式方法的低压电弧中金属蒸气动力学数值模型的建立及屏蔽壁半径对蒸气行为的影响
IF 0.4 4区 工程技术
Electrical Engineering in Japan Pub Date : 2022-02-21 DOI: 10.1002/eej.23374
T. Miyazaki, Yuto Hatanaka, Yasunori Tanaka, Y. Nakano, T. Ishijima, Gaku Asanuma, T. Onchi
{"title":"Development of a numerical model for metal vapor dynamics in low pressure arcs based on moving particle semi‐implicit method and influence of shield wall radius on vapor behavior","authors":"T. Miyazaki, Yuto Hatanaka, Yasunori Tanaka, Y. Nakano, T. Ishijima, Gaku Asanuma, T. Onchi","doi":"10.1002/eej.23374","DOIUrl":"https://doi.org/10.1002/eej.23374","url":null,"abstract":"Numerical simulation was conducted for dynamic behavior of copper vapor in arcs under reduced pressure condition using the developed model. The developed model uses MPS method for atoms and ions, while it uses finite volume method for electron energy and electro‐magnetic fields. In this paper, the influence of shield wall inner radius for vapor dynamics was studied on the heavy particle temperature, electron temperature and ionization degree. The particle in MPS method was assumed to be neutralized and mirror‐reflected on the shield wall. As a result, the shield wall with a larger radius causes lower density of metal vapor, lower ionization degree between the electrodes.","PeriodicalId":50550,"journal":{"name":"Electrical Engineering in Japan","volume":"1934 1","pages":""},"PeriodicalIF":0.4,"publicationDate":"2022-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91116590","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cross‐regional power supply‐demand analysis model based on clustered unit commitment 基于集群机组承诺的跨区域电力供需分析模型
IF 0.4 4区 工程技术
Electrical Engineering in Japan Pub Date : 2022-02-21 DOI: 10.1002/eej.23368
Shintaro Negishi, Keisuke Kimura, Ikumi Suzuki, T. Ikegami
{"title":"Cross‐regional power supply‐demand analysis model based on clustered unit commitment","authors":"Shintaro Negishi, Keisuke Kimura, Ikumi Suzuki, T. Ikegami","doi":"10.1002/eej.23368","DOIUrl":"https://doi.org/10.1002/eej.23368","url":null,"abstract":"In this paper, a new model of electric power supply‐demand analysis based on a clustered unit commitment (CUC) model is proposed. This method enables to derive daily generation plans in multi‐area by minimizing daily generation cost. In the CUC model, the generation units are clustered for the purpose of saving calculation time of the optimization. The proposed model is formulated by Mixed Integer Linear Programming (MILP). The numerical experiment of annual supply‐demand analysis was done to evaluate the availability of the proposed model. As a result, the availability of proposed model was clarified in the view of calculation time and operational results, which are derived by the numerical experiment.","PeriodicalId":50550,"journal":{"name":"Electrical Engineering in Japan","volume":"12 1","pages":""},"PeriodicalIF":0.4,"publicationDate":"2022-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81913068","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Power decoupling control of single‐phase or three‐phase input high‐frequency single‐phase output matrix converters 单相或三相输入高频单相输出矩阵变换器的功率解耦控制
IF 0.4 4区 工程技术
Electrical Engineering in Japan Pub Date : 2022-02-15 DOI: 10.1002/eej.23366
Wataru Kodaka, S. Ogasawara, K. Orikawa
{"title":"Power decoupling control of single‐phase or three‐phase input high‐frequency single‐phase output matrix converters","authors":"Wataru Kodaka, S. Ogasawara, K. Orikawa","doi":"10.1002/eej.23366","DOIUrl":"https://doi.org/10.1002/eej.23366","url":null,"abstract":"This study proposes a matrix converter (MC) control method capable of power decoupling (PD) for a single‐phase input isolated AC‐DC converter. The proposed converter can also be fed by a three‐phase source without any additional components. The PD circuit shares its capacitors with the input filters and its switches with the MC, and absorbs the source power ripple to supply a constant DC voltage for the load. Moreover, the MC control method achieves a sinusoidal source current, a high output frequency, and soft switching. Additionally, the feedback control to compensate for the DC output voltage error is applied. The proposed method is evaluated experimentally.","PeriodicalId":50550,"journal":{"name":"Electrical Engineering in Japan","volume":"6 1","pages":""},"PeriodicalIF":0.4,"publicationDate":"2022-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76427961","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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