Epidemiologic Reviews最新文献

DIGITAL SOLUTIONS FOR TUBERCULOSIS SURVEILLANCE AND CONTROL IN PRIMARY HEALTH CARE: A SCOPING REVIEW. 初级卫生保健中结核病监测和控制的数字解决方案：范围审查。

IF 3.8 2区医学

Epidemiologic Reviews Pub Date : 2026-03-31 DOI: 10.1093/epirev/mxag008

Daniel Souza Sacramento, Samantha Adiely Alecrim Mendonça, Altair Seabra de Farias, Vanderson Sampaio

{"title":"DIGITAL SOLUTIONS FOR TUBERCULOSIS SURVEILLANCE AND CONTROL IN PRIMARY HEALTH CARE: A SCOPING REVIEW.","authors":"Daniel Souza Sacramento, Samantha Adiely Alecrim Mendonça, Altair Seabra de Farias, Vanderson Sampaio","doi":"10.1093/epirev/mxag008","DOIUrl":"https://doi.org/10.1093/epirev/mxag008","url":null,"abstract":"Digital solutions are essential for eliminating tuberculosis as a public health problem. They can be applied across all stages of patient care, health surveillance, program management, workforce development, and community engagement. This study aimed to identify and map digital solutions for tuberculosis developed and/or validated within the context of primary health care. We retrieved studies focusing on digital solutions for tuberculosis targeting managers, health professionals, or patients from Medline, Scopus, Embase, Web of Science, and Google Scholar. We followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses for Scoping Reviews (PRISMA-ScR) guidelines to review, synthesize, and report the findings of articles that met our inclusion criteria. We identified 3133 publications, of which 96 were included after full-text screening. Most solutions focused on treatment monitoring and adherence (46 studies). There was particular emphasis on electronic directly observed therapy, smart pillboxes, and mobile applications. Artificial intelligence-based solutions also emerged, applied to diagnosis, prediction of treatment nonadherence, and prognosis. The findings show that digital solutions have evolved from simple tools to advanced artificial intelligence models. We conclude that the systematic incorporation of these technologies into national protocols is crucial to accelerate progress toward the targets established by the End TB Strategy.","PeriodicalId":50510,"journal":{"name":"Epidemiologic Reviews","volume":" ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2026-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147583107","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Monitoring and evaluation of health disparities for people with disability in low- and middle-income countries: A scoping review. 监测和评价低收入和中等收入国家残疾人的健康差距：范围审查。

IF 3.8 2区医学

Epidemiologic Reviews Pub Date : 2026-03-24 DOI: 10.1093/epirev/mxag009

Sarah Walmsley, Marie Huska, Zoe Aitken, Manjula Marella, Anne Kavanagh, Kaloyan Kamenov, Darryl Barrett, Alexandra Devine

{"title":"Monitoring and evaluation of health disparities for people with disability in low- and middle-income countries: A scoping review.","authors":"Sarah Walmsley, Marie Huska, Zoe Aitken, Manjula Marella, Anne Kavanagh, Kaloyan Kamenov, Darryl Barrett, Alexandra Devine","doi":"10.1093/epirev/mxag009","DOIUrl":"https://doi.org/10.1093/epirev/mxag009","url":null,"abstract":"People with disability experience health inequities and mostly live in low- and middle-income countries (LMIC), as this is where most of the world's population resides. Despite this, existing evidence on health equity for people with disability mostly comes from high-income settings. Monitoring and evaluation of health equity is crucial for countries to address and track progress towards goals, such as the highest attainable standard of health for people with disability. This scoping review aimed to summarise the available literature on approaches and indicators used in LMIC to compare health-related outcomes between people with and without disability. We included peer-reviewed articles published between 2008 and 2024 that compared health-related outcomes between people with and without disability. We identified 59 eligible studies, from a broad range of LMIC. Disability indicators varied, with most studies using one of multiple Washington Group (WG) sets to enable disaggregation of data by disability status. Survey data was most frequently used, with only two studies using administrative data. A wide range of health-related outcomes were explored, with themes of maternal and child health, and human immunodeficiency virus (HIV)-related outcomes emerging as key areas of focus. Disparities were consistently found, with almost all included studies finding poorer outcomes for people with compared to people without disability. There was a noticeable lack of action taken to improve future policy or monitoring and evaluation or to enact real and meaningful change in health equity for people with disability.","PeriodicalId":50510,"journal":{"name":"Epidemiologic Reviews","volume":" ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2026-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147505526","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Genetically predicted high-density lipoprotein traits and pan-disease risk: a systematic review. 遗传预测HDL特征和泛疾病风险：系统综述。

IF 3.8 2区医学

Epidemiologic Reviews Pub Date : 2026-01-29 DOI: 10.1093/epirev/mxag001

Jiexi Wu, Bohan Su, Zhiyao Fan, Hanxiang Zhan

{"title":"Genetically predicted high-density lipoprotein traits and pan-disease risk: a systematic review.","authors":"Jiexi Wu, Bohan Su, Zhiyao Fan, Hanxiang Zhan","doi":"10.1093/epirev/mxag001","DOIUrl":"10.1093/epirev/mxag001","url":null,"abstract":"High-density lipoprotein (HDL) is a highly heterogeneous lipoprotein with multiple physiological functions. However, observational studies present conflicting evidence regarding its association with various diseases. This review systematically summarizes evidence from Mendelian randomization (MR) studies to investigate the causal relationships between HDL-related biomarkers and a wide spectrum of disease outcomes. We systematically searched multiple databases up to November 2024. The causal relationship between HDL and 158 diseases was studied. Findings reveal that the role of HDL is highly disease-specific. Genetically predicted higher HDL levels are protective against most circulatory and digestive system diseases. Conversely, however, they are associated with an increased risk of certain conditions, including breast cancer, intracerebral hemorrhage, and age-related macular degeneration. The MR analyses revealed inconsistent and sometimes conflicting findings for several disease outcomes, notably Alzheimer's disease. This review underscores the context-dependent nature of HDL's effects, which may be driven by factors like HDL particle heterogeneity and functional transformation into a pro-inflammatory state. Future research should move beyond concentration-based metrics to focus on HDL functionality and precise subtyping to fully understand its role in disease etiology.","PeriodicalId":50510,"journal":{"name":"Epidemiologic Reviews","volume":" ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2026-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145971546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Addressing health inequities in treating neuropathic pain: a scoping review of cognitive behavioral therapies, mindfulness, and meditation-based interventions. 解决治疗神经性疼痛的健康不公平：认知行为疗法，正念和冥想干预的范围审查。

IF 3.8 2区医学

Epidemiologic Reviews Pub Date : 2026-01-29 DOI: 10.1093/epirev/mxag002

Robert Buren, Matteo Ponzano, Nathan T Adams, Jane Jun, Kathleen A Martin Ginis

{"title":"Addressing health inequities in treating neuropathic pain: a scoping review of cognitive behavioral therapies, mindfulness, and meditation-based interventions.","authors":"Robert Buren, Matteo Ponzano, Nathan T Adams, Jane Jun, Kathleen A Martin Ginis","doi":"10.1093/epirev/mxag002","DOIUrl":"10.1093/epirev/mxag002","url":null,"abstract":"Chronic pain is the leading cause of disability worldwide and chronic neuropathic pain (NP) disproportionately affects individuals with unmet health care needs, especially those facing health inequities. This scoping review addresses 3 research questions: (1) What are the characteristics and outcomes of cognitive behavioral therapy (CBT), mindfulness, and meditation-based intervention studies designed to manage NP? (2) Do these intervention studies include participants from populations experiencing health inequities? (3) Are the interventions customized to meet the needs of people experiencing health inequities? Ten databases were searched for studies focused on the search terms \"cognitive behavioral therapy,\" \"CBT,\" \"mindfulness meditation,\" \"and neuropathic pain.\" In total, 1732 abstracts were screened and a total of 24 articles from 22 original studies were included. The primary characteristics of the studies showed that 99% of participants had NP attributable to diabetes, cancer, or spinal cord injury. Outcomes were consistent with previous reviews, demonstrating promise for CBT, mindfulness, and meditation-based therapies in relieving NP. However, demographics were poorly reported, and there was little diversity among participants. Individuals from groups experiencing health inequities were largely unrepresented. Although 55% of studies tailored intervention materials and provided content to support long-term practice, few included long-term follow-up to evaluate sustained impact. In general, research on this topic has fallen short in including and addressing the needs of people experiencing health inequities. Future research should prioritize broader participant inclusion criteria, involve individuals with lived experience in intervention design and delivery, and conduct long-term follow-up to enhance the accessibility, relevance, and sustainability of NP interventions.","PeriodicalId":50510,"journal":{"name":"Epidemiologic Reviews","volume":" ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2026-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13089449/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146151284","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Current trends and future prospects of epidemiology of HPV-induced oropharyngeal cancer: a bibliometric analysis. hpv诱导口咽癌流行病学的当前趋势和未来展望：文献计量学分析。

IF 3.8 2区医学

Epidemiologic Reviews Pub Date : 2026-01-29 DOI: 10.1093/epirev/mxag006

Wenjing Guo, Xiujuan Wang, Yangzhi Ren

{"title":"Current trends and future prospects of epidemiology of HPV-induced oropharyngeal cancer: a bibliometric analysis.","authors":"Wenjing Guo, Xiujuan Wang, Yangzhi Ren","doi":"10.1093/epirev/mxag006","DOIUrl":"10.1093/epirev/mxag006","url":null,"abstract":"HPV-induced oropharyngeal cancer (HPV-OPC), caused by persistent infection with high-risk subtypes such as HPV16 and HPV18, poses a significant global health challenge. Epidemiological research on HPV-OPC focuses on prevention, detection, distribution, and disease incidence, revealing an increasing OPC burden related to HPV exposure. The objective of this study was to identify research hotspots and trends in HPV-OPC epidemiology, highlighting the role of epidemiology in guiding prevention and control strategies. A bibliometric analysis of 960 articles (published between 1987 and 2025) from the Web of Science Core Collection, SCOPUS, and PubMed Central was performed, using Python to assess collaborations across countries, institutions, and individuals, as well as literature citation, research timelines, and clustering. Results show a substantial increase in publications, especially from 2013 to 2025, with researchers in United States and China as leading contributors and identifies several prolific authors. Research has primarily focused on HPV vaccination, screening, attributable fraction, and incidence prediction, though challenges such as data quality, vaccination efficacy, limited resource, and modeling limitations also are foci. Future directions include improving data reliability, promoting early and direct vaccination, strengthening international funding, and integrating multiple models. This bibliometric study provides valuable insights into research hotspots and future directions in HPV-OPC, offering researchers and clinicians an overview of current situations and future developments in HPV-OPC epidemiology, potentially improving HPV vaccination and screening strategies and promoting preventive and diagnostic approaches to reduce OPC incidence.","PeriodicalId":50510,"journal":{"name":"Epidemiologic Reviews","volume":" ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2026-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147469782","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Exposure to air pollution and risk of gastrointestinal diseases: a systematic review and meta-analysis of epidemiological evidence. 暴露于空气污染与胃肠道疾病风险：流行病学证据的系统回顾和荟萃分析。

IF 3.8 2区医学

Epidemiologic Reviews Pub Date : 2026-01-29 DOI: 10.1093/epirev/mxag005

Meiqi Hao, Jiayue Zhang, Zuyao Yang, Jinqiu Yuan, Xiangqian Lao, Chengwei Chai, Yin Yang, Hualiang Lin, Yuming Guo, Zilong Zhang

{"title":"Exposure to air pollution and risk of gastrointestinal diseases: a systematic review and meta-analysis of epidemiological evidence.","authors":"Meiqi Hao, Jiayue Zhang, Zuyao Yang, Jinqiu Yuan, Xiangqian Lao, Chengwei Chai, Yin Yang, Hualiang Lin, Yuming Guo, Zilong Zhang","doi":"10.1093/epirev/mxag005","DOIUrl":"10.1093/epirev/mxag005","url":null,"abstract":"Gastrointestinal (GI) diseases represent a significant global health burden, and emerging evidence suggests air pollution may be a risk factor. We reviewed relevant literature and performed a meta-analysis. We searched original studies investigated the associations between long- and short-term exposure to particulate matter (diameter ≤ 2.5 µm [PM2.5], ≤ 10 µm [PM10]) and gaseous pollutants (nitrogen dioxide, sulfur dioxide, carbon monoxide, and ozone [O3]) and GI diseases. DerSimonian and Laird random-effects meta-analyses were conducted when at least 2 studies were available for a given pollutant (per 10 μg m-3 increment) and a specific GI disease. A total of 70 studies were included. Long-term exposure to PM2.5 was significantly associated with increased mortality rate from all GI cancers (OR = 1.128; 95% CI, 1.019-1.248), with the strongest association observed for colorectal cancer (OR = 1.214; 95% CI, 1.061-1.389). For non-cancer GI diseases, long-term exposure to PM2.5 was significantly associated with increased risks of duodenal ulcer (OR = 1.073; 95% CI, 1.057-1.089) and irritable bowel syndrome (OR = 1.353; 95% CI, 1.222-1.497); PM10 was also linked to the latter (OR = 1.108; 95% CI, 1.012-1.213). Short-term exposure, particularly to PM2.5, PM10, and O3, was significantly associated with appendicitis hospitalization (OR = 1.003 [95% CI, 1.001-1.004]; OR = 1.017 [95% CI, 1.015-1.019]; and OR = 1.001 [95% CI, 1.000-1.003], respectively). PM2.5 was also associated with peptic ulcer bleeding (OR = 1.006; 95% CI, 1.001-1.011). Long- and short-term exposures to air pollution, especially PM2.5, are associated with increased risks of GI diseases.","PeriodicalId":50510,"journal":{"name":"Epidemiologic Reviews","volume":" ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2026-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147700509","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Community and societal influences on loneliness and social isolation among young adults: a systematic review of observational studies. 社区和社会对年轻人孤独感和社会隔离的影响：观察性研究的系统回顾。

IF 3.8 2区医学

Epidemiologic Reviews Pub Date : 2026-01-29 DOI: 10.1093/epirev/mxag007

Drew Eleanor Meehan, Anne Grunseit, Neta HaGani, Dafna Merom

{"title":"Community and societal influences on loneliness and social isolation among young adults: a systematic review of observational studies.","authors":"Drew Eleanor Meehan, Anne Grunseit, Neta HaGani, Dafna Merom","doi":"10.1093/epirev/mxag007","DOIUrl":"10.1093/epirev/mxag007","url":null,"abstract":"Loneliness and social isolation are emerging public health concerns among young adults, yet the role of community and societal factors remains poorly understood. Existing research has predominantly focused on individual or interpersonal determinants. This systematic review synthesized observational evidence on community- and societal-level factors associated with loneliness and social isolation among young adults aged 18-30 years. Five databases were searched for observational studies examining place-based community or societal exposures and loneliness or social isolation outcomes. Thirteen eligible studies were identified, and a structured narrative synthesis was undertaken. The exposure variables explored were diverse. Neighborhood characteristics (including trust, safety, and atmosphere), community participation, cultural and societal norms, and structural conditions demonstrated consistent associations with loneliness. Greater neighborhood cohesion, safety, and belonging were protective, whereas neighborhood disorder, minority status, perceived discrimination, and individualistic cultural orientations were associated with greater loneliness. Evidence for social isolation was sparse and methodologically heterogeneous, though area-level disadvantage and remoteness showed emerging relevance. Most studies had a cross-sectional design, and the ways loneliness and social isolation were measured across studies were heterogenous. Community and societal determinants meaningfully shape young adults' experiences of loneliness, but evidence for social isolation remains limited. Findings highlight the need for longitudinal research, improved consistency in the use of measurement tools, and further examination of moderators between individual factors and community influences, which will all contribute to the development of multilevel public health strategies addressing structural and neighborhood conditions.","PeriodicalId":50510,"journal":{"name":"Epidemiologic Reviews","volume":" ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2026-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13148868/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147469819","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Housing affordability and health in people with disability: A scoping review. 住房负担能力与残疾人健康：范围审查。

IF 3.8 2区医学

Epidemiologic Reviews Pub Date : 2026-01-29 DOI: 10.1093/epirev/mxag004

Kate Mason, Tanya Durrand, Glenda M Bishop, Alex Sully, Zoe Aitken

{"title":"Housing affordability and health in people with disability: A scoping review.","authors":"Kate Mason, Tanya Durrand, Glenda M Bishop, Alex Sully, Zoe Aitken","doi":"10.1093/epirev/mxag004","DOIUrl":"10.1093/epirev/mxag004","url":null,"abstract":"Persistent inequities in the social determinants of health contribute to poor health outcomes among people with disability. People with disability are more likely to live in unaffordable housing, which is associated with increased risk of chronic conditions and poor mental health. However, there is limited research on how housing affordability affects health in this priority population. We undertook a scoping review to evaluate existing evidence on the health impacts of living in unaffordable housing for people with disability. Peer-reviewed literature published in English between 2004 and 2024 was considered. The MEDLINE, SocIndex, and Web of Science databases were searched to identify studies examining possible links between housing affordability and any health outcome in a population of people with disability. Two independent reviewers performed study screening and data extraction. Of the 1386 studies identified initially, 3 met the eligibility criteria. The included studies focused on individuals with acquired, psychiatric, or military-related disability. Each study provided evidence suggesting unaffordable housing negatively affected mental health in people with disability. Substantial methodological and conceptual heterogeneity limited direct comparison or synthesis. This review highlights a critical knowledge gap in the relationship between housing affordability and health for people with disability, limiting the development of evidence-informed policy and intervention. People with disability have a fundamental right to access affordable, appropriate housing, as well as the right to the highest attainable standard of health. High-quality, targeted research using consistent definitions of disability and housing affordability, as well as validated health outcome measures, is needed to inform future policy.","PeriodicalId":50510,"journal":{"name":"Epidemiologic Reviews","volume":" ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2026-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13082871/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147379548","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Global seroprevalence of hepatitis E among people living with HIV: a systematic review and meta-analysis. 艾滋病毒感染者戊型肝炎全球血清患病率：系统回顾和荟萃分析

IF 3.8 2区医学

Epidemiologic Reviews Pub Date : 2026-01-29 DOI: 10.1093/epirev/mxag003

Mariana Cavalheiro Magri, Caroline Manchiero, Bianca Peixoto Dantas, Wanderley Marques Bernardo, Edson Abdala, Fátima Mitiko Tengan

{"title":"Global seroprevalence of hepatitis E among people living with HIV: a systematic review and meta-analysis.","authors":"Mariana Cavalheiro Magri, Caroline Manchiero, Bianca Peixoto Dantas, Wanderley Marques Bernardo, Edson Abdala, Fátima Mitiko Tengan","doi":"10.1093/epirev/mxag003","DOIUrl":"10.1093/epirev/mxag003","url":null,"abstract":"Hepatitis E virus (HEV) infection can progress to chronic hepatitis in immunosuppressed individuals. The seroprevalence of hepatitis E among people living with HIV remains controversial. In this systematic review and meta-analysis, the pooled global seroprevalence of hepatitis E among people living with HIV is estimated. This study followed the Preferred Reporting Items for Systematic Review and Meta-Analysis guidelines and was registered in PROSPERO. Searches were conducted in the PubMed, Embase, and Web of Science databases. The seroprevalence of hepatitis E (anti-HEV IgG) among people living with HIV was estimated by meta-analysis using the random-effects model. Subgroup meta-analyses were performed for each continent. A total of 88 studies from 5 continents were included; most were conducted in European countries (48.9%). The pooled seroprevalence of HEV infection was 16.0% (95% CI, 13.0-18.0; I2 = 97.7%). Subgroup analyses revealed seroprevalence rates of 12.0% in Europe, 24.0% in Asia, 19.0% in Africa, and 11.0% in the Americas, and a notably high prevalence was observed in low-income countries (37.0%). Sensitivity analyses restricted to studies with sample sizes of more than 200 participants and risk of bias score ≥ 7 indicated seroprevalence estimates of 18.0% and 15.0%, respectively. In conclusion, this meta-analysis demonstrates a pooled global seroprevalence of HEV infection of 16.0% among people living with HIV, ranging from 11.0% to 24.0% across the continents.","PeriodicalId":50510,"journal":{"name":"Epidemiologic Reviews","volume":" ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2026-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147357566","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Risk of new diagnoses and exacerbations of chronic conditions after SARS-CoV-2 infection: a systematic review update. SARS-CoV-2感染后新诊断和慢性病加重的风险：最新系统综述

IF 3.8 2区医学

Epidemiologic Reviews Pub Date : 2026-01-29 DOI: 10.1093/epirev/mxaf018

Lindsay A Gaudet, Jennifer Pillay, Dianne Zakaria, Sabrina Saba, Ben Vandermeer, Maria Tan, Lisa Hartling

{"title":"Risk of new diagnoses and exacerbations of chronic conditions after SARS-CoV-2 infection: a systematic review update.","authors":"Lindsay A Gaudet, Jennifer Pillay, Dianne Zakaria, Sabrina Saba, Ben Vandermeer, Maria Tan, Lisa Hartling","doi":"10.1093/epirev/mxaf018","DOIUrl":"10.1093/epirev/mxaf018","url":null,"abstract":"The large number of people infected by SARS-CoV-2 necessitates estimation of the future health care burdens. We updated a systematic review examining associations between SARS-CoV-2 infection and incidence of new diagnoses and exacerbations of chronic conditions. Updated searches were run September 4, 2024, in the MEDLINE and Embase databases for observational studies with a control group, adjustment by sex and comorbid conditions, and reporting age-stratified data for 1 or more chronic condition category (n = 12) or condition type (n = 46) of interest. Two human reviewers screened 50% of titles and abstracts, then DistillerAI acted as second reviewer. Two human reviewers assessed full texts of relevant studies for eligibility based on a priori criteria. One reviewer extracted data and assessed risk of bias using the JBI cohort studies checklist; a second reviewer verified results data and risk-of-bias assessments. Pooled hazard ratios (HRs) were estimated with inverse-variance weighting. Using the Grading of Recommendations, Assessment, Development, and Evaluation approach, 2 reviewers assessed certainty in conclusions of little to no association (ie, HR = 0.75-1.25), small to moderate association (ie, HR = 0.51-0.74 or 1.26-1.99), or large association (ie, HR ≤ 0.50 or ≥ 2.00). We identified 46 new studies and brought forward 23 studies from the original review. After SARS-CoV-2 infection, there is probably increased risk of new diagnoses for several chronic conditions, especially in adults. Most findings are based on data from earlier pandemic periods; their relevance to contemporary populations is uncertain due to differences in vaccination rates and circulating variants of concern. PROSPERO registration identifier CRD42024585278.","PeriodicalId":50510,"journal":{"name":"Epidemiologic Reviews","volume":" ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2026-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12858253/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145566092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0