Epidemiologic Reviews最新文献

Risk factors for bloodstream infection caused by carbapenem-resistant Enterobacterales in patients with haematological malignancies: a systematic review and meta-analysis. 血液恶性肿瘤患者中碳青霉烯耐药肠杆菌引起血流感染的危险因素：一项系统综述和荟萃分析。

IF 9.6 2区医学

Epidemiologic Reviews Pub Date : 2026-10-16 DOI: 10.1093/epirev/mxag015

Antonio Russo, Nicola Coppola, Carlo Torti, Enrico Maria Trecarichi

{"title":"Risk factors for bloodstream infection caused by carbapenem-resistant Enterobacterales in patients with haematological malignancies: a systematic review and meta-analysis.","authors":"Antonio Russo, Nicola Coppola, Carlo Torti, Enrico Maria Trecarichi","doi":"10.1093/epirev/mxag015","DOIUrl":"https://doi.org/10.1093/epirev/mxag015","url":null,"abstract":"With the aim to identify risk factors associated with bloodstream infections (BSI) caused by carbapenem-resistant Enterobacterales (CRE) in patients with hematological malignancies (HM), a systematic review and meta-analysis were conducted in accordance with PRISMA guidelines and registered in PROSPERO (CRD420251176369). MEDLINE, PubMed, and Embase were searched for studies published up to 31 October 2025. Observational studies evaluating risk factors for laboratory-confirmed CRE BSI in adult or paediatric patients with HMs were included. Adjusted and unadjusted effect estimates were analysed separately. Pooled odds ratios (ORs) with 95% confidence intervals (CIs) were calculated using random- or fixed-effects models based on heterogeneity. Six studies were included. In meta-analyses based on adjusted estimates, prior exposure to carbapenems (OR 8.01, 95% CI 2.98-21.54), cephalosporins (OR 4.11, 95% CI 1.53-11.05) and fluoroquinolones (OR 3.94, 95% CI 1.83-8.44) resulted to be associated with CRE BSI. Meta-analyses of crude data showed additional associations with CRE colonization, previous infections, newly diagnosed disease or first relapse, chronic liver disease, diabetes mellitus, and prior exposure to multiple antibiotic classes. Prior exposure to carbapenems, cephalosporins, and fluoroquinolones was consistently associated with CRE BSI in adjusted analyses. However, the small number of included studies and the wide confidence intervals limit the precision and generalizability of these estimates. Previous antibiotic exposure should therefore be considered as part of an integrated risk assessment together with colonization status, previous microbiological findings, clinical severity, and local epidemiology, rather than as a stand-alone criterion for empirical therapy.","PeriodicalId":50510,"journal":{"name":"Epidemiologic Reviews","volume":" ","pages":""},"PeriodicalIF":9.6,"publicationDate":"2026-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149197506","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Reporting quality and risk of bias in systematic reviews of clinical prediction models: a cross-sectional overview of 1004 studies. 临床预测模型系统评价的报告质量和偏倚风险：1004项研究的横断面综述

IF 9.6 2区医学

Epidemiologic Reviews Pub Date : 2026-09-15 DOI: 10.1093/epirev/mxag013

Mei Zhang, Yunhui Xia, Hangfeng Mo, Yujia Zhu, Leyi Fang, Qianyu Xiang, Jiantong Shen, Li Wang, Jianlin Lou

{"title":"Reporting quality and risk of bias in systematic reviews of clinical prediction models: a cross-sectional overview of 1004 studies.","authors":"Mei Zhang, Yunhui Xia, Hangfeng Mo, Yujia Zhu, Leyi Fang, Qianyu Xiang, Jiantong Shen, Li Wang, Jianlin Lou","doi":"10.1093/epirev/mxag013","DOIUrl":"https://doi.org/10.1093/epirev/mxag013","url":null,"abstract":"This review aims to assess the condition and primary factors influencing reporting quality and bias in systematic reviews of clinical prediction models. We conducted a critical review through three databases (PubMed, Embase, Cochrane Library) from inception to January 7, 2023. Screening, data extraction, and assessment were conducted independently by pairs. Employing TRIPOD-SRMA and ROBIS to evaluate the reporting and methodological quality. Data were summarized through descriptive statistics, visual analysis, and multiple linear regression analysis. 1004 reviews were included. Reporting quality was poor. The average main text quality score was 16.4 ± 4.1 out of 33 points, and the average abstract quality score was 5.2 ± 1.7 out of 12 points. Year, economic level, purpose of the model, impact factors, and types of systematic reviews were associated with the quality of abstracts or the main text. Merely 0.2% (2/1004) of the reviews assessed were classified as having low risk of bias. Systematic reviews of clinical prediction models demonstrate inadequate reporting and significant risk of bias. Optimizing research design, enforcing stricter reporting guidelines, promoting protocol pre-registration, and enhancing journal review processes to boost reliability and transparency are warranted.","PeriodicalId":50510,"journal":{"name":"Epidemiologic Reviews","volume":" ","pages":""},"PeriodicalIF":9.6,"publicationDate":"2026-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148972135","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Genetically predicted high-density lipoprotein traits and pan-disease risk: a systematic review. 遗传预测HDL特征和泛疾病风险：系统综述。

IF 9.6 2区医学

Epidemiologic Reviews Pub Date : 2026-01-29 DOI: 10.1093/epirev/mxag001

Jiexi Wu, Bohan Su, Zhiyao Fan, Hanxiang Zhan

{"title":"Genetically predicted high-density lipoprotein traits and pan-disease risk: a systematic review.","authors":"Jiexi Wu, Bohan Su, Zhiyao Fan, Hanxiang Zhan","doi":"10.1093/epirev/mxag001","DOIUrl":"10.1093/epirev/mxag001","url":null,"abstract":"High-density lipoprotein (HDL) is a highly heterogeneous lipoprotein with multiple physiological functions. However, observational studies present conflicting evidence regarding its association with various diseases. This review systematically summarizes evidence from Mendelian randomization (MR) studies to investigate the causal relationships between HDL-related biomarkers and a wide spectrum of disease outcomes. We systematically searched multiple databases up to November 2024. The causal relationship between HDL and 158 diseases was studied. Findings reveal that the role of HDL is highly disease-specific. Genetically predicted higher HDL levels are protective against most circulatory and digestive system diseases. Conversely, however, they are associated with an increased risk of certain conditions, including breast cancer, intracerebral hemorrhage, and age-related macular degeneration. The MR analyses revealed inconsistent and sometimes conflicting findings for several disease outcomes, notably Alzheimer's disease. This review underscores the context-dependent nature of HDL's effects, which may be driven by factors like HDL particle heterogeneity and functional transformation into a pro-inflammatory state. Future research should move beyond concentration-based metrics to focus on HDL functionality and precise subtyping to fully understand its role in disease etiology.","PeriodicalId":50510,"journal":{"name":"Epidemiologic Reviews","volume":" ","pages":""},"PeriodicalIF":9.6,"publicationDate":"2026-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145971546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Exposure to air pollution and risk of gastrointestinal diseases: a systematic review and meta-analysis of epidemiological evidence. 暴露于空气污染与胃肠道疾病风险：流行病学证据的系统回顾和荟萃分析。

IF 9.6 2区医学

Epidemiologic Reviews Pub Date : 2026-01-29 DOI: 10.1093/epirev/mxag005

Meiqi Hao, Jiayue Zhang, Zuyao Yang, Jinqiu Yuan, Xiangqian Lao, Chengwei Chai, Yin Yang, Hualiang Lin, Yuming Guo, Zilong Zhang

{"title":"Exposure to air pollution and risk of gastrointestinal diseases: a systematic review and meta-analysis of epidemiological evidence.","authors":"Meiqi Hao, Jiayue Zhang, Zuyao Yang, Jinqiu Yuan, Xiangqian Lao, Chengwei Chai, Yin Yang, Hualiang Lin, Yuming Guo, Zilong Zhang","doi":"10.1093/epirev/mxag005","DOIUrl":"10.1093/epirev/mxag005","url":null,"abstract":"Gastrointestinal (GI) diseases represent a significant global health burden, and emerging evidence suggests air pollution may be a risk factor. We reviewed relevant literature and performed a meta-analysis. We searched original studies investigated the associations between long- and short-term exposure to particulate matter (diameter ≤ 2.5 µm [PM2.5], ≤ 10 µm [PM10]) and gaseous pollutants (nitrogen dioxide, sulfur dioxide, carbon monoxide, and ozone [O3]) and GI diseases. DerSimonian and Laird random-effects meta-analyses were conducted when at least 2 studies were available for a given pollutant (per 10 μg m-3 increment) and a specific GI disease. A total of 70 studies were included. Long-term exposure to PM2.5 was significantly associated with increased mortality rate from all GI cancers (OR = 1.128; 95% CI, 1.019-1.248), with the strongest association observed for colorectal cancer (OR = 1.214; 95% CI, 1.061-1.389). For non-cancer GI diseases, long-term exposure to PM2.5 was significantly associated with increased risks of duodenal ulcer (OR = 1.073; 95% CI, 1.057-1.089) and irritable bowel syndrome (OR = 1.353; 95% CI, 1.222-1.497); PM10 was also linked to the latter (OR = 1.108; 95% CI, 1.012-1.213). Short-term exposure, particularly to PM2.5, PM10, and O3, was significantly associated with appendicitis hospitalization (OR = 1.003 [95% CI, 1.001-1.004]; OR = 1.017 [95% CI, 1.015-1.019]; and OR = 1.001 [95% CI, 1.000-1.003], respectively). PM2.5 was also associated with peptic ulcer bleeding (OR = 1.006; 95% CI, 1.001-1.011). Long- and short-term exposures to air pollution, especially PM2.5, are associated with increased risks of GI diseases.","PeriodicalId":50510,"journal":{"name":"Epidemiologic Reviews","volume":" ","pages":""},"PeriodicalIF":9.6,"publicationDate":"2026-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147700509","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Current trends and future prospects of epidemiology of HPV-induced oropharyngeal cancer: a bibliometric analysis. hpv诱导口咽癌流行病学的当前趋势和未来展望：文献计量学分析。

IF 9.6 2区医学

Epidemiologic Reviews Pub Date : 2026-01-29 DOI: 10.1093/epirev/mxag006

Wenjing Guo, Xiujuan Wang, Yangzhi Ren

{"title":"Current trends and future prospects of epidemiology of HPV-induced oropharyngeal cancer: a bibliometric analysis.","authors":"Wenjing Guo, Xiujuan Wang, Yangzhi Ren","doi":"10.1093/epirev/mxag006","DOIUrl":"10.1093/epirev/mxag006","url":null,"abstract":"HPV-induced oropharyngeal cancer (HPV-OPC), caused by persistent infection with high-risk subtypes such as HPV16 and HPV18, poses a significant global health challenge. Epidemiological research on HPV-OPC focuses on prevention, detection, distribution, and disease incidence, revealing an increasing OPC burden related to HPV exposure. The objective of this study was to identify research hotspots and trends in HPV-OPC epidemiology, highlighting the role of epidemiology in guiding prevention and control strategies. A bibliometric analysis of 960 articles (published between 1987 and 2025) from the Web of Science Core Collection, SCOPUS, and PubMed Central was performed, using Python to assess collaborations across countries, institutions, and individuals, as well as literature citation, research timelines, and clustering. Results show a substantial increase in publications, especially from 2013 to 2025, with researchers in United States and China as leading contributors and identifies several prolific authors. Research has primarily focused on HPV vaccination, screening, attributable fraction, and incidence prediction, though challenges such as data quality, vaccination efficacy, limited resource, and modeling limitations also are foci. Future directions include improving data reliability, promoting early and direct vaccination, strengthening international funding, and integrating multiple models. This bibliometric study provides valuable insights into research hotspots and future directions in HPV-OPC, offering researchers and clinicians an overview of current situations and future developments in HPV-OPC epidemiology, potentially improving HPV vaccination and screening strategies and promoting preventive and diagnostic approaches to reduce OPC incidence.","PeriodicalId":50510,"journal":{"name":"Epidemiologic Reviews","volume":" ","pages":""},"PeriodicalIF":9.6,"publicationDate":"2026-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147469782","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Monitoring and evaluation of health disparities for people with disability in low- and middle-income countries: a scoping review. 监测和评价低收入和中等收入国家残疾人的健康差距：范围审查。

IF 9.6 2区医学

Epidemiologic Reviews Pub Date : 2026-01-29 DOI: 10.1093/epirev/mxag009

Sarah Walmsley, Marie Huska, Zoe Aitken, Manjula Marella, Anne Kavanagh, Kaloyan Kamenov, Darryl Barrett, Alexandra Devine

{"title":"Monitoring and evaluation of health disparities for people with disability in low- and middle-income countries: a scoping review.","authors":"Sarah Walmsley, Marie Huska, Zoe Aitken, Manjula Marella, Anne Kavanagh, Kaloyan Kamenov, Darryl Barrett, Alexandra Devine","doi":"10.1093/epirev/mxag009","DOIUrl":"10.1093/epirev/mxag009","url":null,"abstract":"People with disability experience health inequities and mostly live in low- and middle-income countries (LMICs), because that is where most of the world's population resides. Despite this, existing evidence on health equity for people with disability mostly comes from high-income settings. Monitoring and evaluation of health equity are crucial for countries to address and track progress toward goals, such as the highest attainable standard of health for people with disability. This scoping review summarizes the available literature on approaches and indicators used in LMICs to evaluate health-related outcomes between people with and without disability. Peer-reviewed articles were included that were published between 2008 and 2024 that compared health-related outcomes between these 2 populations. We identified 59 eligible studies from a broad range of LMICs. Disability indicators varied, with most studies using 1 of multiple Washington Group question sets to enable disaggregation of data by disability status. Survey data were the type most frequently used; only 2 studies used administrative data. A wide range of health-related outcomes were explored; themes of maternal and child health and HIV-related outcomes emerged as key areas of focus. Disparities were consistently found, with almost all included studies reporting poorer outcomes for people with compared with people without disability. There was a noticeable lack of action taken to improve future policy or monitoring and evaluation or to enact real and meaningful change in health equity for people with disability.","PeriodicalId":50510,"journal":{"name":"Epidemiologic Reviews","volume":" ","pages":""},"PeriodicalIF":9.6,"publicationDate":"2026-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13175618/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147505526","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Addressing health inequities in treating neuropathic pain: a scoping review of cognitive behavioral therapies, mindfulness, and meditation-based interventions. 解决治疗神经性疼痛的健康不公平：认知行为疗法，正念和冥想干预的范围审查。

IF 9.6 2区医学

Epidemiologic Reviews Pub Date : 2026-01-29 DOI: 10.1093/epirev/mxag002

Robert Buren, Matteo Ponzano, Nathan T Adams, Jane Jun, Kathleen A Martin Ginis

{"title":"Addressing health inequities in treating neuropathic pain: a scoping review of cognitive behavioral therapies, mindfulness, and meditation-based interventions.","authors":"Robert Buren, Matteo Ponzano, Nathan T Adams, Jane Jun, Kathleen A Martin Ginis","doi":"10.1093/epirev/mxag002","DOIUrl":"10.1093/epirev/mxag002","url":null,"abstract":"Chronic pain is the leading cause of disability worldwide and chronic neuropathic pain (NP) disproportionately affects individuals with unmet health care needs, especially those facing health inequities. This scoping review addresses 3 research questions: (1) What are the characteristics and outcomes of cognitive behavioral therapy (CBT), mindfulness, and meditation-based intervention studies designed to manage NP? (2) Do these intervention studies include participants from populations experiencing health inequities? (3) Are the interventions customized to meet the needs of people experiencing health inequities? Ten databases were searched for studies focused on the search terms \"cognitive behavioral therapy,\" \"CBT,\" \"mindfulness meditation,\" \"and neuropathic pain.\" In total, 1732 abstracts were screened and a total of 24 articles from 22 original studies were included. The primary characteristics of the studies showed that 99% of participants had NP attributable to diabetes, cancer, or spinal cord injury. Outcomes were consistent with previous reviews, demonstrating promise for CBT, mindfulness, and meditation-based therapies in relieving NP. However, demographics were poorly reported, and there was little diversity among participants. Individuals from groups experiencing health inequities were largely unrepresented. Although 55% of studies tailored intervention materials and provided content to support long-term practice, few included long-term follow-up to evaluate sustained impact. In general, research on this topic has fallen short in including and addressing the needs of people experiencing health inequities. Future research should prioritize broader participant inclusion criteria, involve individuals with lived experience in intervention design and delivery, and conduct long-term follow-up to enhance the accessibility, relevance, and sustainability of NP interventions.","PeriodicalId":50510,"journal":{"name":"Epidemiologic Reviews","volume":" ","pages":""},"PeriodicalIF":9.6,"publicationDate":"2026-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13089449/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146151284","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

How population-level drug supply data are integrated into health outcomes research: a scoping review. 如何将人口水平的药物供应数据纳入健康结果研究：范围审查。

IF 9.6 2区医学

Epidemiologic Reviews Pub Date : 2026-01-29 DOI: 10.1093/epirev/mxag010

Samuel Tobias, Joshua Bird, Michael R Law, Jane A Buxton, Lianping Ti

{"title":"How population-level drug supply data are integrated into health outcomes research: a scoping review.","authors":"Samuel Tobias, Joshua Bird, Michael R Law, Jane A Buxton, Lianping Ti","doi":"10.1093/epirev/mxag010","DOIUrl":"10.1093/epirev/mxag010","url":null,"abstract":"Despite growing recognition that changes in the unregulated drug supply are central drivers of drug-related morbidity and mortality, there is little consensus on how population-level drug supply data are, or should be, incorporated into health outcomes research. Here, we describe the role unregulated drug supply data play in health outcomes research in the substance use field. We searched the MEDLINE, Embase, Scopus, and Europe PubMed Central databases and relevant published conference abstracts on May 28, 2025. Studies must have incorporated population-level or ecological measures of the unregulated drug supply (i.e., nonpharmaceutical) as an independent variable and reported either individual-level or population-level health outcomes, including but not limited to drug poisonings (i.e., overdose), deaths (drug-related or all-cause), hospitalizations, and emergency department visits. Of the 31 included studies, 26 were conducted in the United States and 5 in Canada. Drug supply data were used in multiple analytic roles, including as primary variables and as covariates (or predictors) of health outcomes. These data were derived from 4 distinct sources: law enforcement seizures (n = 25), drug-checking services (n = 2), hospital or clinic urinalysis results (n = 3), or postmortem toxicology results (n = 3). Most studies assessed the impact of drug supply metrics on drug toxicity (overdose) counts or rates within a given region (n = 27). We found that population-level drug supply data demonstrate predictive capacity for health outcomes and may represent an underutilized confounding factor in policy evaluation. However, their incorporation into health research remains inconsistent and conceptually fragmented.","PeriodicalId":50510,"journal":{"name":"Epidemiologic Reviews","volume":" ","pages":""},"PeriodicalIF":9.6,"publicationDate":"2026-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13218782/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147870245","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Community and societal influences on loneliness and social isolation among young adults: a systematic review of observational studies. 社区和社会对年轻人孤独感和社会隔离的影响：观察性研究的系统回顾。

IF 9.6 2区医学

Epidemiologic Reviews Pub Date : 2026-01-29 DOI: 10.1093/epirev/mxag007

Drew Eleanor Meehan, Anne Grunseit, Neta HaGani, Dafna Merom

{"title":"Community and societal influences on loneliness and social isolation among young adults: a systematic review of observational studies.","authors":"Drew Eleanor Meehan, Anne Grunseit, Neta HaGani, Dafna Merom","doi":"10.1093/epirev/mxag007","DOIUrl":"10.1093/epirev/mxag007","url":null,"abstract":"Loneliness and social isolation are emerging public health concerns among young adults, yet the role of community and societal factors remains poorly understood. Existing research has predominantly focused on individual or interpersonal determinants. This systematic review synthesized observational evidence on community- and societal-level factors associated with loneliness and social isolation among young adults aged 18-30 years. Five databases were searched for observational studies examining place-based community or societal exposures and loneliness or social isolation outcomes. Thirteen eligible studies were identified, and a structured narrative synthesis was undertaken. The exposure variables explored were diverse. Neighborhood characteristics (including trust, safety, and atmosphere), community participation, cultural and societal norms, and structural conditions demonstrated consistent associations with loneliness. Greater neighborhood cohesion, safety, and belonging were protective, whereas neighborhood disorder, minority status, perceived discrimination, and individualistic cultural orientations were associated with greater loneliness. Evidence for social isolation was sparse and methodologically heterogeneous, though area-level disadvantage and remoteness showed emerging relevance. Most studies had a cross-sectional design, and the ways loneliness and social isolation were measured across studies were heterogenous. Community and societal determinants meaningfully shape young adults' experiences of loneliness, but evidence for social isolation remains limited. Findings highlight the need for longitudinal research, improved consistency in the use of measurement tools, and further examination of moderators between individual factors and community influences, which will all contribute to the development of multilevel public health strategies addressing structural and neighborhood conditions.","PeriodicalId":50510,"journal":{"name":"Epidemiologic Reviews","volume":" ","pages":""},"PeriodicalIF":9.6,"publicationDate":"2026-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13148868/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147469819","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Correction to: Global incidence and risk factors for injury-related bloodstream infections: a scoping review. 修正为：损伤相关血流感染的全球发生率和危险因素：范围审查。

IF 9.6 2区医学

Epidemiologic Reviews Pub Date : 2026-01-29 DOI: 10.1093/epirev/mxag014

引用次数: 0