European Journal of Cardiovascular Prevention & Rehabilitation最新文献

{"title":"Oral Session V. Cardiovascular disease prevention: a success story?","authors":"","doi":"10.1177/17418267090160s115","DOIUrl":"https://doi.org/10.1177/17418267090160s115","url":null,"abstract":"","PeriodicalId":50492,"journal":{"name":"European Journal of Cardiovascular Prevention & Rehabilitation","volume":"38 1","pages":"S117 - S118"},"PeriodicalIF":0.0,"publicationDate":"2009-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/17418267090160s115","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"65490935","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Oral Session IV. Translational cardiovascular science","authors":"F. Sofi, G. Pratesi, R. Pulli, C. Pratesi, T. Suvorava, M. Weber, S. Valcaccia, Thao-Vi Dao, G. Kojda, M. Oppermann","doi":"10.1177/17418267090160s111","DOIUrl":"https://doi.org/10.1177/17418267090160s111","url":null,"abstract":"O397 Balance between circulating endothelial progenitor cells (EPCs) and mature circulating endothelial cells (CECs) in relation to the severity of peripheral arterial disease FCesari, F Sofi, RCaporale, G Pratesi, R Pulli, C Pratesi, RAbbate, GFGensini University of Florence, Florence, Italy, Azienda Ospedaliero-Universitaria Careggi, Florence, Italy Topic: Peripheral vascular disease Introduction: the maintenance of endothelial health depends, not only on the local milieu, but also on circulating endothelial progenitor cells (EPCs) derived from the bone marrow. Indeed, EPCs support the integrity of vascular endothelium and promote revascularisation of ischemic areas. On the other hand, circulating mature endothelial cells (CECs) are considered a marker of endothelial injury. Previous studies demonstrated reduced number of EPCs in peripheral arterial disease (PAD) patients, but few data are available on CECs. Aim of our study was to contemporary assess EPCs and CECs in PAD patients in relation to the severity of the disease. Methods: in 30 PAD patients [22 M/ 8 F; median age: 69 (45-86) years] we measured circulating EPCs and CECs by using flow cytometry. EPCs were defined as CD34+KDR+, CD133+KDR+ and CD34+CD133+KDR+, while CECs were defined as CD146+/CD31+/CD45-/CD61-. Results: a significant trend of decrease (p<0.05) in relation to the clinical severity of the disease, as seen by Fontaine’s stages, was observed for CD133+/KDR+ EPCs [stage IIa: 0.093 (0.060.25); stage IIb: 0.049 (0.02-0.16); stage III: 0.03 (0.02-0.05); stage IV: 0.035 (0.02-0.08) cells/ ÿ ÙL]. On the contrary, a significant (p<0.05) increase was showed by CECs [stage IIa: 0.077 (0.02-0.13); stage IIb: 0.084 (0.02-0.19); stage III: 0.15 (0.05-0.19); stage IV: 0.22 (0.08-0.33) cells/ ÿ ÙL]. In order to evaluate the balance existing between EPCs and CECs in relation to the clinical progression of the disease, we calculated the CECs/EPCs ratio. By increasing Fontaine’s stage, a progressive and significant (p<0.05) increase in ratio value was observed, indicating a prominent role of CECs with respect to EPCs number [stage IIa: 0.62 (0.2-2.30); stage IIb: 1.22 (0.23-7.67); stage III: 6.39 (1.43-7.71); stage IV: 6.14 (1-16)] Conclusions: our results demonstrate an inbalance between EPCs and CECs in PAD patients in relation to the progression of the disease, possibly indicating that the endothelial damage observed in these patients is not sufficiently repaired by a concomitant increase of the regenerative capacity of EPCs.","PeriodicalId":50492,"journal":{"name":"European Journal of Cardiovascular Prevention & Rehabilitation","volume":"16 1","pages":"S86 - S87"},"PeriodicalIF":0.0,"publicationDate":"2009-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/17418267090160s111","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"65490805","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Moderated Poster Session II: Prevention and health policy","authors":"J. Skoumas, K. Aznaouridis, VMetaxa, F. Platsouka, L. Papadimitriou, C. Pitsavos, C. Stefanadis, M. Lorgeril, P. Salen, F. Laporte, A. Castelnuovo, V. Krogh, M. Donati, A. Tverdal, F. Visseren, A. Algra","doi":"10.1177/17418267090160s103","DOIUrl":"https://doi.org/10.1177/17418267090160s103","url":null,"abstract":"M135 Metabolic syndrome is a predictor of outcome in patients with familial combined hyperlipidemia CMasoura, J Skoumas, K Aznaouridis, VMetaxa, F Platsouka, L Papadimitriou, C Pitsavos, C Stefanadis Athens, Greece Topic: Lipids and atherosclerosis Purpose: Familial combined hyperlipidemia (FCH) is a polygenic lipid disorder associated with premature cardiovascular disease. It is unknown whether metabolic syndrome (MetS) modulates cardiovascular risk in FCH patients. Methods: We studied prospectively 644 FCH patients (421 men) for 9.2 3.6 years. Demographic characteristics and biochemical parameters were evaluated at enrolment, before the initiation of treatment. The diagnosis of MetS was based on the modified ATP III criteria (glucose >100 mg/dl). Hard cardiovascular end-points, like acute myocardial infarction (AMI) and cardiovascular death, were recorded during the follow-up. Results: The 323 patients with MetS were older (50.8 10.2 vs. 46.7 11.0 years, öÀ<0.001) and had higher triglyceride and glucose levels, but they had lower HDL-C levels compared with patients without MetS (all öÀ<0.001). There was no difference in total cholesterol. The combined endpoint (AMI/death) occurred in 29 patients with MetS and in 9 patients without MetS (9.0% vs. 2.8%, P=0.001). Kaplan-Meier analysis showed a significant difference in the event-free survival between the 2 groups (P=0.005, figure). Multivariate analysis (Cox regression) showed that MetS at enrolment predicts AMI/death independent of age, sex or previous cardiovascular disease (adjusted odds ratio 2.25, 95% CI 1.06-4.75, P=0.034). Conclusions: MetS represents an independent predictor of major cardiovascular events in FCH patients.","PeriodicalId":50492,"journal":{"name":"European Journal of Cardiovascular Prevention & Rehabilitation","volume":"11 1","pages":"S26 - S28"},"PeriodicalIF":0.0,"publicationDate":"2009-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/17418267090160s103","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"65491031","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Oral Session II. Exercise training in coronary artery disease: what is good for whom","authors":"S. Dimopoulos, V. Anagnostakou, E. Chatzimichail, L. Karatzanos, K. Malliaras, N. Diakos, A. Tasoulis, S. Nanas, M. Bilińska, M. Kosydar-Piechna, A. Gąsiorowska, T. Mikulski, K. Nazar, R. Piotrowicz, G. Caminiti, M. Volterrani, A. Cerrito, R. Massaro, S. Bovone, M. Beato, A. Mancuso, M. Rosano, E. Roelleke, B. Zoller, M. Schneider, U. Wirtz, A. Radzewitz","doi":"10.1177/17418267090160s109","DOIUrl":"https://doi.org/10.1177/17418267090160s109","url":null,"abstract":"O385 Randomised comparison of the effects of interval aerobic plus strength training versus interval aerobic training alone on endothelium function in chronic heart failure ST Dimopoulos, V Anagnostakou, E Chatzimichail, L Karatzanos, K Malliaras, N Diakos, A Tasoulis, S Nanas Cardiopulmonary Rehabilitation Centre, ‘Evgenidio’ Hospital, University of Athens, Greece, 3rd Clinic of Cardiology, ‘Alexandra’ Hospital, University of Athens, Greece Topic: Cardiovascular rehabilitation Purpose: Exercise training confers beneficial effects on endothelial function in patients with chronic heart failure (CHF). However the optimal form of training remains debated. This randomised study compared the effects of interval aerobic combined with strength training versus aerobic training alone on endothelial function in CHF patients. Methods: We studied 28 consecutive patients in optimally treated, stable CHF who were randomly assigned to 3 times weekly training sessions for 3 months, consisting of a) 40 min of aerobic interval training (30 sec effort 60 sec rest at intensity 100% VO2peak) (n=14), versus b) 20 min of similar aerobic, interval training plus 20 min of strength training of various muscle groups (quadriceps, hamstrings, muscles of the shoulder zone, biceps) (n=14). All patients underwent maximal, symptom-limited cardiopulmonary exercise testing and ultrasound evaluation of endothelial function by flow-mediated vasodilation (FMD) before and after the programme. Results: Peak oxygen uptake increased significantly and similarly in both groups, from 15.7 4.0 to 17.2 3.7 ml/kg/min in the aerobic training alone group (p=0.03), and from 15.7 6.0 to 18.3 6.3 ml/kg/min in the combined training group (p=0.006). A significant improvement in FMD (p=0.002) was observed in the combined training group, in contrast to the aerobic training alone group (p=ns); the improvement was significantly greater in the combined training than in the aerobic training alone group (p <0.05). Conclusions: A 3-month exercise-training programme improved endothelial function and physical performance in CHF patients. Combining high-intensity, interval aerobic exercise with strength training had a greater beneficial effect on endothelial function than interval, aerobic exercise alone.","PeriodicalId":50492,"journal":{"name":"European Journal of Cardiovascular Prevention & Rehabilitation","volume":"16 1","pages":"S82 - S83"},"PeriodicalIF":0.0,"publicationDate":"2009-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/17418267090160s109","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"65491215","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Oral Session III. Is now the time for universal preparticipation screening?","authors":"","doi":"10.1177/17418267090160s110","DOIUrl":"https://doi.org/10.1177/17418267090160s110","url":null,"abstract":"","PeriodicalId":50492,"journal":{"name":"European Journal of Cardiovascular Prevention & Rehabilitation","volume":"16 1","pages":"S84 - S85"},"PeriodicalIF":0.0,"publicationDate":"2009-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/17418267090160s110","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"65491228","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Moderated Poster Session IV: Sport cardiology","authors":"D. Niederseer, A. Egger, J. Niebauer, Z. Pagava, G. Saatashvili, D. Trapaidze, B. Tsinamdzgvrishvili, R. Agladze, C. Beller, K. Deyerling, G. Tenderich, D. Horstkotte, R. Koerfer, K. Mellwig, F. Trujillo, J. Fernández-Armenta, C. Fernández‐Vivancos, V. Pedrosa, B. Prado, M. Borbolla, A. Castro, J. Cruz","doi":"10.1177/17418267090160s106","DOIUrl":"https://doi.org/10.1177/17418267090160s106","url":null,"abstract":"M280 Cardiovascular events during FIFA Soccer World Cup 2006 D Niederseer, A Egger, J Niebauer Paracelsus Medical University, Salzburg, Austria Topic: Sports cardiology Objectives: Recently, an increase in the incidence of cardiovascular events in Bavaria during FIFA Soccer World Cup 2006 (WC) has been reported. A significant pooling of cardiovascular events on days the German team played as well as on the day of the final game was shown. However, in this excellent report only a limited number of cardiac diagnoses were analysed. Methods: In order to assess further acute cardiac disorders we requested data for the period of the WC (June 9-July 9, 2006) but also for control periods (May 1-July 31, 2003 and 2005; May 1June 8, 2006 i.e. before WC and July 10-31, 2006 i.e. after WC) from the Bavarian Council for Statistics and Data Management on diagnoses. The following diagnoses were assessed: myocardial infarction (ICD-10; I 21); cardiac arrest (I 46); paroxysmal tachycardia (I 47); atrial fibrillation, atrial flutter (I 48); all remaining tachyarrhythmias (I 49). Results: Despite an increase in cardiac events among Bavarians on the days the German team played, there was no overall increase during the WC or respective control periods (Table 1). Conclusion: Whereas the original analysis by Wilbert-Lampen et al. urges organisers of largescale events to be especially prepared on days on which local teams play, our data somewhat assure us that watching such enjoyable events does not lead to an overall increase in cardiac events beyond that seen during control periods. We rather hypothesise that emotional stress induced by watching soccer pools cardiovascular events to one specific moment i.e. a soccer game, but would have likely occurred anyway within the control period and thus within the very near future.","PeriodicalId":50492,"journal":{"name":"European Journal of Cardiovascular Prevention & Rehabilitation","volume":"16 1","pages":"S54 - S56"},"PeriodicalIF":0.0,"publicationDate":"2009-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/17418267090160s106","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"65491110","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Moderated Poster Session V. Basic science","authors":"M. Sandri, S. Gielen, V. Adams, N. Mangner, R. Hoellriegel, S. Erbs, A. Linke, G. Schuler, L. Bruyndonckx, C. V. Berckelaer, G. Frederix, P. Beckers, C. Vrints, V. Conraads, V. Vargová, M. Pytliak, V. Mechírová, T. Thomaes","doi":"10.1177/17418267090160s112","DOIUrl":"https://doi.org/10.1177/17418267090160s112","url":null,"abstract":"M418 Age related alterations of endothelial function in patients with chronic heart failure and healthy subjects Effects of exercise training M Sandri, S Gielen, V Adams, N Mangner, R Hoellriegel, S Erbs, A Linke, G Schuler University of Leipzig Heart Centre, Leipzig, Germany Topic: Exercise physiology, testing and training Background: Impairment of endothelial function may occur in both physiologic aging and chronic heart failure (CHF). It has, however, never been assessed, whether the degree of endothelial dysfunction in CHF patients is influenced by age and if the well established beneficial effects of endurance exercise training on endothelial function are diminished in old age. Methods: In this study we randomised 50 pts. with stable CHF (age 61.4 2.7 years, EF 26.3 1.5%, VO2max 13.8 2.3ml/kg*min) and 50 healthy subjects (HS) (age 59.8 3.1 years, EF 60 1%, VO2max 21.1 3.1 ml/kg*min) to a training (T) or a control group (C). To detect possible aging effects we included subjects below 55 (young) and above 65 years (old). Subjects in the T-group exercised 4 times daily at 60 to 70% of VO2max for 4 weeks under supervision. At baseline and after the intervention, flow-mediated dilatation (FMD) was assessed by a highresolution radial ultrasound (NIUS2). Results: As compared to young HS, old HS showed at baseline a reduced FMD (young: 16.7 1.1%; old: 12.1 1.6%; p<0.05). In CHF patients, endothelial function was impaired (young 9.3 0.9%; old: 9.1 1.2%). No difference of these baseline parameters between the age groups was observed (p=0.72) in this subgroup. As a result of ET, FMD improved from 12.2 0.9% to 15.9 1.2% in old HS (p<0.05), while it remained unchanged in young training HS and C respectively. In young and old patients with CHF four weeks of ET resulted in a significant change in FMD (young: from 9.2 0.8 to 13.1 1.2; p<0.05; old: from 9.0 1.1 to 12.4 1.0 p<0.05). In C no effect was detectable. Conclusions: The present trial provides new insight into the age-dependency of cardiovascular training effects: Among HS aging is associated with the development of endothelial dysfunction. In CHF both young and old patients exhibit a similar degree of endothelial dysfunction. Four weeks of ET are effective in improving endothelial dysfunction in old HS and in all age groups of CHF patients. The training effect was not significantly diminished among older patients with underlining the potentials of rehabilitation interventions in this patient group, where CHF is most prevalent.","PeriodicalId":50492,"journal":{"name":"European Journal of Cardiovascular Prevention & Rehabilitation","volume":"16 1","pages":"S88 - S90"},"PeriodicalIF":0.0,"publicationDate":"2009-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/17418267090160s112","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"65490814","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Moderated Poster Session III: Cardiac rehabilitation","authors":"G. Silva, O. Sousa, N. Ferreira, N. Bettencourt, F. Miranda, M. Teixeira, V. Ribeiro, F. Cacciatore, F. Mazzella, D. Acanfora, G. Longobardi, A. Nicolino, L. Odierna, G. Furgi, F. Rengo, D. Bacquer, F. Kittel, M. Kornitzer, G. Backer, S. Dimopoulos, G. Tzanis, V. Agapitou, H. Pozios, A. Bouchla, E. Zerva","doi":"10.1177/17418267090160s105","DOIUrl":"https://doi.org/10.1177/17418267090160s105","url":null,"abstract":"M270 Can a short cardiac rehabilitation programme influence novel markers of cardiovascular risk evaluated by computed tomography imaging? Preliminary results of a randomised clinical study R P Lima, G Silva, O Sousa, N Dias Ferreira, N Bettencourt, F Miranda, M Teixeira, V Gama Ribeiro Gaia, Portugal Topic: Cardiovascular rehabilitation Purpose: To evaluate the impact of a short course (8 weeks), moderate intensity cardiac rehabilitation programme (CRP) on markers of systemic inflammation and cardiovascular risk (total adipose tissue (TAP), subcutaneous adipose tissue (SAT), visceral adipose tissue (VAT) at abdominal level) by computed tomography imaging (CT-scan) in postinfarction patients. Methods: Fifty-four postinfarction patients were randomised into two groups: group R composed of 31 patients (27 males; mean age 53.9 years 11.4; mean LV ejection fraction (EF) 54.2% 8.9%) entered a 8 weeks CRP, whereas group NR, composed of 23 patients (18 males; mean age 57.7 years; mean EF 49.8% 10.8%) did not enter any CRP being only followed in an outpatient basis. CT-scan was performed before and after the programme and the evolution of the different parameters of CT-scan in the two groups was analysed. Results: After the CRP, group R patients did not show any significant improvement in total adipose tissue when compared with group NR patients (4 TAT -12.8 43.7 vs -11.34 47.57 respectively; p = 0.9). Equally, there were no significant differences between the groups on subcutaneous adipose tissue (4 SAT -3.85 in group R vs -10.5 in group NR; p = 0.79). Visceral adipose tissue has decreased in group R (-8.94) while has increased in group NR (+2.31), but this difference was not statistically significant (p=0.64). Conclusions: In our population an 8 week CRP did not significantly affect the adipose tissue. However, at 3-month, we can observe a slight trend toward reduction in visceral adipose tissue. The limited duration of the programme and the \"low\" exercise loads applied may have accounted for these results. More intense and prolonged comprehensive CR programmes are probably needed to obtain an impact, mainly in the visceral adipose tissue.","PeriodicalId":50492,"journal":{"name":"European Journal of Cardiovascular Prevention & Rehabilitation","volume":"16 1","pages":"S51 - S53"},"PeriodicalIF":0.0,"publicationDate":"2009-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/17418267090160s105","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"65491101","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Poster Session IV","authors":"A. Jurko, I. Tonhajzerova, Z. Havlicekova, P. Wandell, M. Hellénius, M. Markus, J. Stritzke, W. Lieb, A. Luchner, A. Doering, U. Keil, H. Hense, H. Schunkert, H. Neuhauser, U. Ellert, M. Thamm, A. S. Rosario","doi":"10.1177/17418267090160s114","DOIUrl":"https://doi.org/10.1177/17418267090160s114","url":null,"abstract":"P438 Systolic blood pressure amplification. The Czech post-MONICA study P Wohlfahrt, D Palous, M Ingrischova, R Cifkova IKEM, Prague, Czech Republic, VFN, Prague, Czech Republic Topic: Hypertension Background: Central (cSBP) and brachial (bSBP) systolic blood pressures usually differ substantially. Recent studies have shown cSBP to be a better cardiovascular risk predictor than bSBP. On the other hand, brachial blood pressure measurement is more readily accessible in clinical practice. The aim of our study was to identify factors affecting the difference between cSBP and bSBP expressed as systolic blood pressure amplification [(bSBP-cSBP)/bSBP]. Methods: A subgroup of 299 patients aged 47.7 11.2 years (52% of men) from the Czech postMONICA study dealing with a randomly selected representative population sample were examined. After 10 minutes of rest in the recumbent position, peripheral blood pressure measurement and central blood pressure approximation were performed using an Omron HEM 9000 AI. Results: Systolicbloodpressureamplificationcorrelatedwithage(r=-0.47,p<0.001),height(r=0.47, p<0.001), weight (r= 0.22, p<0.001), mean arterial blood pressure (r= -0.23, p<0.001), heart rate (r= 0.127, p<0.05), triglyceride logarithm (r= -0.13, p<0.05), total (r= -0.165, p<0.01) and LDLcholesterol (r= -0.15, p<0.01), arterial hypertension (r= -0.22, p<0.001), and smoking status expressed as cigarette-years (r= -0.28, p<0.05). In multiple stepwise regression analysis, only age, height, heart rate, mean arterial blood pressure, waist-to-hip ratio, triglyceride logarithm, and arterial hypertension remained to be associated significantly with systolic blood pressure amplification. Conclusion: Our results suggest that the difference between central and brachial systolic blood pressure is affected by age and cardiovascular risk factors. This is probably due to large vessel stiffening by atherosclerosis.","PeriodicalId":50492,"journal":{"name":"European Journal of Cardiovascular Prevention & Rehabilitation","volume":"16 1","pages":"S116 - S94"},"PeriodicalIF":0.0,"publicationDate":"2009-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/17418267090160s114","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"65490924","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Moderated Poster Session I Epidemiology","authors":"K. Bennett, I. Perry, H. Mcgee, K. Morgan, E. Shelley, S. Jennings, S. Capewell, P. Whincup, S. Wannamethee, O. Papacosta, A. Thomson, L. Lennon, R. Morris, V. Regecová, E. Kellerová, EC Cizmarova, A. Jurko, EO Ondriskova, U. Keil, D. Bacquer, G. Ambrosio, Ž. Reiner, D. Gaita","doi":"10.1177/17418267090160s101","DOIUrl":"https://doi.org/10.1177/17418267090160s101","url":null,"abstract":"M12 Explaining the continuing decrease in CHD mortality in Ireland: comparing population health behaviour and health service contributions from 1985-2000 with 2000-2006 K Bennett, I Perry, H Mcgee, K Morgan, E Shelley, S Jennings, S Capewell St James Hospital, Dublin, Ireland, University College Cork, Cork, Ireland, Royal College Surgeons of Ireland, Dublin, Ireland, HSE, Dublin, Ireland, University of Liverpool, Liverpool, United Kingdom Topic: Cardiovascular epidemiology Mortality from cardiovascular disease has been falling in several countries with previously high rates. Irish CHD mortality rates fell dramatically from 1985 to 2000. Between 2000 and 2006 there was a further 45% decrease in CHD mortality rates amongst both men and women aged 2584 years (44% men; 46% women) in Ireland, i.e. 2315 fewer deaths than expected or ‘deaths prevented or postponed (DPPs)’ between 2000 and 2006. Objective: the aim of this study was to use the validated IMPACT CHD mortality model to examine the CHD mortality fall in Ireland between 2000 and 2006; to determine the contribution of risk factor changes and \"evidence based\" treatments to this decline; and to compare with similar analyses for 1985-2000. Methods: the cell-based IMPACT CHD mortality model in Microsoft Excel has been described in detail elsewhere. Data on risk factors was obtained from the SLû N 1998, 2002 and 2007 health and lifestyle surveys. Medical treatment data was available from the national prescribing databases, the Heartwatch programme for secondary prevention therapy in primary care, as well as the EUROASPIRE II and III (2001) and EUROHeart Failure I and II surveys. Results: approximately half of the decrease in CHD deaths between 2000 and 2006 were attributed to improvements in uptake of treatments (48%), particularly secondary prevention (15%), and treatments for chronic angina (11%) and for heart failure in the community and hospital (12%). For risk factors, the largest contribution came from reductions in population cholesterol (25%). Reduction in smoking contributed a disappointing 6% (compared with 26% in 1985-2000 comparisons); reflecting little progress in smoking cessation since 2000. There was little evidence of an improvement in population blood pressure reduction, or physical activity levels. There was further deterioration in the rates of diabetes and obesity since 2000, which is contributing to increased deaths from CHD. Conclusion: the substantial decrease in CHD mortality in Ireland continues in both men and women. Important contributors include reductions in total cholesterol levels in the population, a slight reduction in smoking prevalence, and increased medical and surgical interventions. Despite these positive changes, the continued increase in levels of obesity and diabetes could result in the adverse trends recently observed in other countries such as the UK, US and Australia, with a reversal of the mortality decline, particularly among the youngest groups.","PeriodicalId":50492,"journal":{"name":"European Journal of Cardiovascular Prevention & Rehabilitation","volume":"16 1","pages":"S1 - S3"},"PeriodicalIF":0.0,"publicationDate":"2009-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/17418267090160s101","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"65490976","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}