European Journal of Cardiovascular Prevention & Rehabilitation最新文献

{"title":"Intrauterine growth restriction: no unifying risk factor for the metabolic syndrome in young adults.","authors":"Anne M Euser,&nbsp;Friedo W Dekker,&nbsp;Stein I Hallan","doi":"10.1097/HJR.0b013e328331d2c3","DOIUrl":"https://doi.org/10.1097/HJR.0b013e328331d2c3","url":null,"abstract":"<p><strong>Background: </strong>The validity and appropriateness of the metabolic syndrome as a cardiovascular risk factor are increasingly debated, partly because of the lack of a unifying underlying pathophysiological mechanism. Intrauterine growth retardation (low birth weight by sex and gestational length) has been associated with several cardiovascular problems and could be an important underlying risk factor for the metabolic syndrome.</p><p><strong>Methods: </strong>The association between intrauterine growth retardation (from the Norwegian Medical Birth Registry) and the metabolic syndrome in 7435 men and women aged 20-30 years from the population-based HUNT 2 study was studied with logistic regression using fractional polynomial models.</p><p><strong>Results: </strong>In men, there were significant associations with several of the separate components of the metabolic syndrome: central obesity (exponential, P<0.001), raised triglycerides (negative linear, P = 0.018), reduced HDL-cholesterol (U-shaped, P = 0.086), raised blood pressure (negative linear, P = 0.036), and impaired glucose tolerance (negative linear, P = 0.036). In women, there were significant associations with central obesity (positive linear, P<0.001) and raised blood pressure (negative linear, P = 0.003) but not with the other components. When combining these components into the metabolic syndrome, an exponential association was found in men (P = 0.017), that is, increased risk in patients with high birth weight only. In women, there was no association at all (P = 0.959).</p><p><strong>Conclusion: </strong>Low birth weight was not associated with the metabolic syndrome at young adult age. Several associations between birth weight and the separate components of the syndrome were found, however, but these associations were partly in different directions.</p>","PeriodicalId":50492,"journal":{"name":"European Journal of Cardiovascular Prevention & Rehabilitation","volume":" ","pages":"314-20"},"PeriodicalIF":0.0,"publicationDate":"2010-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1097/HJR.0b013e328331d2c3","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40029767","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Poster Session IV. Cardiac rehabilitation","authors":"","doi":"10.1177/17418267100170s231","DOIUrl":"https://doi.org/10.1177/17418267100170s231","url":null,"abstract":"","PeriodicalId":50492,"journal":{"name":"European Journal of Cardiovascular Prevention & Rehabilitation","volume":"70 1","pages":"S106 - S110"},"PeriodicalIF":0.0,"publicationDate":"2010-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/17418267100170s231","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"65491413","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Poster Session II: Cardiac rehabilitation","authors":"PS Munk, UM Breland, P. Aukrust, T. Ueland, JT Kvaloy, AI Larsen, P. Blanc, C. Verkindt, S. Maunier, S. Chopra, F. Prieur, S. Kostic, D. Djordjevic, M. Rihter, V. Mitic, M. Lovic, D. Vulic, Tasic","doi":"10.1177/17418267100170s213","DOIUrl":"https://doi.org/10.1177/17418267100170s213","url":null,"abstract":"P223 Clinical benefits of additional resistance-type exercises during endurance-based exercise intervention in coronary artery disease patients DRMJ Hansen, P Dendale, T Broekmans, M Roelants, A Daniels, K Hensen, JL Rummens, BO Eijnde Virga Jesse Hospital, Rehabilitation and Health Centre, Hasselt, Belgium, Rehabilitation & Health Care Research Centre, Dept. Health Care, PHL-University College, Hasselt, Belgium, Laboratory of Experimental Hematology, Virga Jesse Hospital, Hasselt, Belgium Topic: Cardiovascular rehabilitation Purpose: In the early rehabilitation of coronary artery disease (CAD) patients, resistance-type exercises are advocated in addition to endurance-type exercises. However, the clinical effects of these additional exercises remain to be explored. Methods: 55 CAD patients were included and randomly assigned to 6 weeks of endurance exercise training or combined endurance and resistance exercise training (mean 18 sessions). All subjects performed 3 exercises sessions/week at 65% of baseline VO2max, for 40 min/session. In the combined group, leg extension and leg squat exercise were additionally executed: 2 series, 12 up to 25 repetitions. Following parameters were evaluated: maximal exercise capacity and ventilatory threshold (ergospirometry test), body composition (dual x-ray absorptiometry scan), hematology, blood lipid profile and glycemic control, blood endothelial progenitor cell content, muscle strength (dynamometry test on Biodex), home-based habitual activity. Results: 42 CAD patients completed this intervention. In the combined-trained group upper leg lean tissue mass increased significantly (from 20.7 3.2 to 21.1 3.4kg, p<0.05), but not in the endurance-trained group (from 20.4 3.2 to 20.4 3.3kg, p>0.05). The significant improvement in blood haemoglobin content, hematocrit, VO2max, ventilatory threshold, and muscle isokinetic and endurance strength was similar between groups. The significant reduction in adipose tissue was equal between groups. In the combined-trained group, blood HDL cholesterol content increased significantly (from 40 10 to 45 10mg/dl, p<0.05), and white blood cell count decreased significantly (from 6.6 1.5 to 6.0 1.4 10(9), p<0.05), but not in the endurancetrained group (from 40 6 to 41 7mg/dl, and from 6.6 1.1 to 6.4 0.9 10(9), p>0.05). Conclusion: The addition of resistance-type exercises during an endurance exercise intervention in CAD results into a greater increase in blood HDL cholesterol content and decrease in white blood cell count. Therefore, cardiovascular disease risk could be reduced by greater magnitude in CAD patients when adding resistance-type exercises towards endurance-exercise intervention by a novel physiological mechanism.","PeriodicalId":50492,"journal":{"name":"European Journal of Cardiovascular Prevention & Rehabilitation","volume":"17 1","pages":"S47 - S50"},"PeriodicalIF":0.0,"publicationDate":"2010-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/17418267100170s213","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"65490954","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Moderated Poster Session V: Sports cardiology","authors":"S. Basavarajaiah, J. Rawlins, NChandra, LCarby, E. Sawyer, S. Sharma, E. Tataradze, Z. Sopromadze, N. Chabashvili, E. Chumburidze, Buleishvili","doi":"10.1177/17418267100170s221","DOIUrl":"https://doi.org/10.1177/17418267100170s221","url":null,"abstract":"P307 Relationship between exercise related blood pressure response and differences in magnitude of left venticular hypertrophy between african/afro-carribean (black) athletes and caucasian athletes SGati,MPapadakis, S Basavarajaiah, J Rawlins, NChandra, LCarby, E Sawyer, S Sharma Univeristy Hospital Lewisham, London, United Kingdom, King’s College Hospital, London, United Kingdom Topic: Sports cardiology Purpose: Participation in regular physical exercise is associated with a greater magnitude of left ventricular hypertrophy in male athletes of African/Afro-Caribbean origin (black athletes) compared with athletes of Caucasian origin of similar age and size, participating in similar exercise disciplines. The precise genetic, biochemical and physiological mechanisms for these differences is unknown. However, the role of exercise related blood pressure response as a determinant of exercise induced left ventricular hypertrophy has not been tested. Aim: The study sought to investigate whether there were differences in exercise related blood pressure response in black athletes and Caucasian athletes. Method: Between 2004 and 2007, 300 black athletes and 300 white athletes (mean age 20 5 years) participating at regional or national level underwent echocardiographic evaluation. Of these 54 black athletes (18%) and 12 white athletes (4%) exhibited a LV wall thickness>12mm indicating LVH. Black and Caucasian athletes with left ventricular hypertrophy of >12mm were subject to exercise stress testing with simultaneous blood pressure recording using the Bruce protocol. All athletes were exercised to the point of volitional exhaustion. Results: Black athletes exhibited a greater mean left ventricular wall thickness compared with white athletes (11.3 1mm; range 13-16mm v. 10 1.5mm; range 13-14mm: p<0.0001). The blood pressure responses to exercise are tabulated below (Table 1). There were no significant differences in blood pressure response to exercise when comparing black athletes and white athletes. Conclusion:The greater magnitude of left ventricular hypertrophy in blacks is not explained by a difference in exercise related blood pressure response","PeriodicalId":50492,"journal":{"name":"European Journal of Cardiovascular Prevention & Rehabilitation","volume":"328 1","pages":"S65 - S66"},"PeriodicalIF":0.0,"publicationDate":"2010-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/17418267100170s221","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"65491394","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Poster Session IV. Exercise physiology","authors":"","doi":"10.1177/17418267100170s233","DOIUrl":"https://doi.org/10.1177/17418267100170s233","url":null,"abstract":"","PeriodicalId":50492,"journal":{"name":"European Journal of Cardiovascular Prevention & Rehabilitation","volume":"17 1","pages":"S112 - S113"},"PeriodicalIF":0.0,"publicationDate":"2010-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/17418267100170s233","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"65491467","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Poster Session III: Epidemiology and public health","authors":"C. Guijarro, E. Alegrı́a, J. Lozano, B. González-Timón, Gomez-Salinas, G. Vitale, J. Millán, E. Gomez-Salinas, BGonzalez-Timon, J. González-Juanatey, M. Lejsková, P. Stavek, S. Zecova, J. Kunišek, L. Zaputović, Z. Čubranić, L. Kunišek, V. Peršić, A. Ružić, M. Žuvić, Butorac, S. V. Rapaić","doi":"10.1177/17418267100170s224","DOIUrl":"https://doi.org/10.1177/17418267100170s224","url":null,"abstract":"P346 Adherence with statins in a real-life setting is better when cardiovascular risk factors increase T Couffinhal, P Latry, M Molimar, B Begaud, M Lafitte, K Martin-Latry University Hospital of Bordeaux Hospital Haut Leveque, Departement of Cardiology, Pessac, France, Direction Regionale du Service Medical de l’Assurance Maladie d’Aquitaine, CNAMTS, Bordeaux, France, Inserm U 657, Universite Victor Segalen Bordeaux 2, Bordeaux, France Topic: Pharmacoepidemiology Background: Several studies have shown poor adherence to statin treatments and several associated factors have been highlighted: younger age, insufficient revenue, absence of cardiovascular morbidity, women, number of coprescribed drugs. While the factors for poor adherence have been highlighted, the impact of their combination on adherence is not clear. Purpose: To estimate adherence for statins and whether it differs according to the number of cardiovascular risk factors. Methods: A cohort study was conducted using data from the French social security insurance database. Patients were included if they submitted a reimbursement form for a prescription for statins between September 1 and December 31, 2004, and did not receive any statin treatment for 6 months previous to this. Patients were followed up 15 months. Statin use was considered a proxy for hypercholesterolemia. The cohort was split into three groups according to their number of additional cardiovascular risk factors that included age and gender, diabetes mellitus and cardiovascular disease (using co-medications as a proxy). Adherence was assessed for each group by using four parameters: (i) proportion of days covered by statins, (ii) regularity of the treatment over time, (iii) persistence, and (iv) the patient s understanding of the treatment. Results: 16,397 newly treated patients were identified. Of these statin users, 21.7 % did not have additional cardiovascular risk factors. Thirty-one percent had two cardiovascular risk factor and 47% had at least three risk factors. All the parameters showed a sub-optimal adherence whatever the group: days covered ranged from 56 % to 72 %, regularity ranged from 23 % to 33 % and persistence ranged from 44 % to 59 %, but adherence was better for those with a higher number of cardiovascular risk factors. Conclusions: The results confirm that long-term drug treatments are a difficult challenge, particularly in patients at lower risk.","PeriodicalId":50492,"journal":{"name":"European Journal of Cardiovascular Prevention & Rehabilitation","volume":"17 1","pages":"S75 - S82"},"PeriodicalIF":0.0,"publicationDate":"2010-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/17418267100170s224","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"65491489","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Poster Session III: Cardiac rehabilitation: psychosocial factors, stress and quality of life","authors":"","doi":"10.1177/17418267100170s225","DOIUrl":"https://doi.org/10.1177/17418267100170s225","url":null,"abstract":"","PeriodicalId":50492,"journal":{"name":"European Journal of Cardiovascular Prevention & Rehabilitation","volume":"17 1","pages":"S83 - S87"},"PeriodicalIF":0.0,"publicationDate":"2010-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/17418267100170s225","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"65491501","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Poster Session II: Basic science: cardiovascular physiology","authors":"I. Osipova, O. Antropova, A. Zalzman, N. Lobanova, K. Golovina, C. Langer, S. Regenzuck, F. Buuren, K.-P. Mellwig, C. Beller, M. Vlachojannis, Fruend, D. Horstkotte, T. Suvorava","doi":"10.1177/17418267100170s216","DOIUrl":"https://doi.org/10.1177/17418267100170s216","url":null,"abstract":"P252 Peculiarities of left ventricular remodeling in subjects with masking arterial hypertension I Osipova, O Antropova, A Zalzman, N Lobanova, K Golovina Altay State Medical University, Barnaul, Russian Federation, Departmental Clinical Hospital, Barnaul, Russian Federation Topic: Early detection of asymptomatic disease The purpose of the study was to estimate target-organs condition in patients with masking (isolated ambulatory) hypertension having operator professions. 329 males were included in the study. According to blood pressure monitoring during working and rest hours the subjects were distributed into 2 groups. 197 patients with masking arterial hypertension at working place formed the 1st group, 132 males with low-stress work and essential hypertension formed the second group. All subjects were performed echocardiography, duplex scanning of brachiocephal arteries. In comparison with 2nd group subjects, 1st group subjects had lower early diastolic filling rate (peak E) over 9.5% (pU0,001) and higher late diastolic filling rate (peak A) over 19.1% (pU0,001), less ratio E/A over 33.3% (pU0,001).Type I diastolic dysfunction was revealed in 147 (74.6%) and 79 (59.8%) subjects of the 1st and 2nd groups correspondingly, that is over 14.8% (XU8.0, pU0,005) more frequent in males with masking arterial hypertension. Left ventricular (LV) hypertrophy was revealed in 75 (38.1%) and 37 (28.1%) subjects of 1 and 2 group correspondingly, thus its frequency was comparable. In 1st group subjects normal LV geometry was detected in 72 (36.5%) subjects, concentric remodeling in 50 (25.4%) subjects, concentric LV hypertrophy 48 (24.4%) subjects, eccentric LV hypertrophy was detected in 27 (13.7%) subjects. In 2nd group subjects normal LV geometry was detected in 59 (44.7%) subjects, concentric remodeling in 36 (27.3%) subjects, concentric LV hypertrophy 16 (12.1%) subjects, eccentric LV hypertrophy was detected in 12.3% subjects (XU7.9; pU0.05). Consequently, in comparison with patients with essential hypertension the patients with masking arterial hypertension have more frequent LV diastolic dysfunction, comparable frequency of LV hypertrophy but its more adverse concentric type.","PeriodicalId":50492,"journal":{"name":"European Journal of Cardiovascular Prevention & Rehabilitation","volume":"17 1","pages":"S55 - S56"},"PeriodicalIF":0.0,"publicationDate":"2010-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/17418267100170s216","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"65491686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Moderated Poster Session IV: Exercise physiology","authors":"G. Fazio, S. Milia, I. Brusca, S. Paterna, G. Novo, S. Novo, P. Di, Pasquale, G. G. VeigaGuimaraes, Jfc Belli, LN Pascoalino, V. Carvalho, VS Issa, Lgb Cruz, E. Bocchi, J. Neder","doi":"10.1177/17418267100170s210","DOIUrl":"https://doi.org/10.1177/17418267100170s210","url":null,"abstract":"P160 Determinants and prognostic value of the VE/VCO2 slope as compared to neurohormonal activation in elderly patients with CAD and preserved LV function J H A J De Sutter, N Van De Veire, J Philippe, M De Buyzere Ghent University, Ghent, Belgium Topic: Biomarkers Background and study aims:The VE/CO2 slope is considered as a powerful predictor of cardiac events in patients with heart failure. In this study we evaluated the determinants and prognostic value of the VE/VCO2 slope in the ever increasing population of elderly patients with CAD and preserved LV function. We also compared the predictive value of the VE/CO2 slope with NTproBNP as marker of neurohormonal activation. Methods:We studied 89 patients 70 years or older (mean age 75 4 years, 85% men) with CAD and LVEF = 50% (mean LVEF 64 9 %). All patients underwent a maximal bicycle spiroergometry for the evaluation of VO2max and the VE/CO2 slope. Serum NT-proBNP, creatinine and high sensitivity CRP were determined. Echocardiography was performed to evaluate E/E as marker of LV filling pressures. Patients were followed for a median follow-up of 32months for the combined end-point of mortality, AMI, PCI, CABG or hospitalisation for heart failure. Results:Mean VO2max was 15,5 4,1 ml/kg/min andmean VE/CO2 slope was 32 6. Tertiles of VE/CO2 slope were associated with higher levels of NT-proBNP, hsCRP and E/E (all p-values < 0.05) but not with age, VO2max or creatinine levels. Patients with events during follow-up (n1⁄416) had higher values of VE/CO2 slope, NT-proBNP and creatinine but no differences were noted for age, VO2max, hsCRP and E/E . ROC analysis showed AUC values of 0,74 (95%CI 0,59-0,89, p<0.01) for NT-proBNP and 0,67 (95% CI 0,53-0,81, p<0.05) for VE/CO2 slope. In multivariate Cox regression analysis, VE/CO2 slope appeared as an independent predictor (p<0.05) for cardiac events. However, after introduction of NT-proBNP in the model, VE/CO2 did not remain as predictor, in contrast to NT-proBNP (p<0.01). Conclusions: In elderly patients with CAD and preserved LV function, increased levels of VE/ VCO2 slope are related to higher LV filling pressures as well as higher levels of parameters of neurohormonal and inflammatory activation. Although the VE/CO2 slope is a predictor of cardiac events, its predictive power is weaker as compared to NT-proBNP.","PeriodicalId":50492,"journal":{"name":"European Journal of Cardiovascular Prevention & Rehabilitation","volume":"17 1","pages":"S31 - S32"},"PeriodicalIF":0.0,"publicationDate":"2010-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/17418267100170s210","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"65490829","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Poster Session II: Prevention and health policy: tobacco, economics, clinical trials and quality of care","authors":"J. Cerveira, F. Paccaud, V. Mooser, G. Waeber, P. Vollenweider, Cornuz, P. Jankowski, S. Surowiec, M. Loster, A. Pajak, K. Kawecka-Jaszcz, P. Papasavvas, C. Karkadaris, D. Panagiotakos","doi":"10.1177/17418267100170s211","DOIUrl":"https://doi.org/10.1177/17418267100170s211","url":null,"abstract":"P169 Escitalopram prevents depression in patients with acute coronary syndrome (DECARD): a randomized controlled trial BH Hansen, JA Hanash, A Rasmussen, JF Hansen, NLT Andersen, M Birket-Smith Bispebjerg Hospital of the Copenhagen University Hospital, Copenhagen, Denmark Topic: Controlled clinical trials Background and aims: Prevalence of depression in patients recovering from acute coronary syndrome (ACS) i.e., myocardial infarction and unstable angina is higher than in general population and depression is associated with poor cardiac outcomes and higher mortality. Despite these findings no trials of prevention of depression in post-ACS patients has been undertaken. The aim of the DEpression in Coronary ARtery Disease (DECARD) study was to evaluate the efficacy of one year preventive treatment with selective serotonin reuptake inhibitor escitalopram. Methods: In a double blind randomized study 240 non-depressed patients were enrolled within 8 weeks after ACS to treatment with escitalopram or matching placebo (5-20 mg). Primary outcome measure was development of clinical depression and score >13 on Hamilton Depression Scale (HDS). Results: During the one year study period, 12 patients developed depression, two in the escitalopram and ten in the placebo group (p1⁄4.017). Twenty-four patients had significant depressive symptoms (HDS>13), 7 in the escitalopram and 17 in the placebo group (p1⁄4.030). Conclusion: Escitalopram prevented depression and depressive symptoms during the first year after ACS.","PeriodicalId":50492,"journal":{"name":"European Journal of Cardiovascular Prevention & Rehabilitation","volume":"17 1","pages":"S33 - S34"},"PeriodicalIF":0.0,"publicationDate":"2010-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/17418267100170s211","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"65490875","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}