European Journal of Contraception and Reproductive Health Care最新文献

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The impact of the Roe v. Wade overturn on birth control prescriptions and sterilisation procedures in rural NC. 推翻 "罗伊诉韦德案 "对北卡罗来纳州农村地区节育处方和绝育手术的影响。
IF 1.9 4区 医学
European Journal of Contraception and Reproductive Health Care Pub Date : 2024-12-01 Epub Date: 2024-10-10 DOI: 10.1080/13625187.2024.2409231
Eloise Joubert, Todd Anderson, Valeria Barreto-Nadal, David Schutzer
{"title":"The impact of the <i>Roe v. Wade</i> overturn on birth control prescriptions and sterilisation procedures in rural NC.","authors":"Eloise Joubert, Todd Anderson, Valeria Barreto-Nadal, David Schutzer","doi":"10.1080/13625187.2024.2409231","DOIUrl":"10.1080/13625187.2024.2409231","url":null,"abstract":"<p><strong>Background/introduction: </strong>On June 24, 2022, the Supreme Court overturned the 1973 verdict in the <i>Roe v. Wade</i> legal suit that had established the constitutional right to medical abortion [1]. With the right to abortion now being left to the states, many restrictions regarding abortion procedures are being established [2]. We aim to evaluate whether this has led to an increase in the number of birth control prescriptions and sterilisation procedures at Cape Fear Valley Medical Centre in rural North Carolina.</p><p><strong>Methods: </strong>SlicerDicer program within EPIC medical records database was used to retrieve the records of all women that had an obstetrics and gynaecology appointment with Cape Fear Valley Health System between 11/01/21-12/31/2022 for contraception. The data was sorted into race/ethnicity, age, and types of birth control. Principal outcomes measured the trends in birth control prescription or sterilisation procedure appointments before and after the overturn of <i>Roe v. Wade</i>.</p><p><strong>Results: </strong>Contraceptive pill prescriptions decreased from 51.70% to 32.40%. IUD insertions decreased from 39.40% to 11.30%. Injectable birth control remained consistent, at approximately 16%. Nexplanon implantations dropped from 20.60% to 9.70%. Lastly, sterilisation procedures increased from 6.7% to 10.7%.</p><p><strong>Conclusion: </strong>Majority of birth control prescriptions decreased following the overturn of <i>Roe v. Wade</i>, except for sterilisation, which increased by 4.0%. This may indicate that women are now looking for more permanent birth control options after the overturn of <i>Roe v. Wade</i>. Future research should investigate whether similar trends of increasing prevalence of sterilisation procedures is seen throughout the United States.</p>","PeriodicalId":50491,"journal":{"name":"European Journal of Contraception and Reproductive Health Care","volume":" ","pages":"294-297"},"PeriodicalIF":1.9,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142479716","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Neighbourhood environment and early menarche among adolescent girls of five countries. 五个国家少女的邻里环境与月经初潮过早。
IF 1.9 4区 医学
European Journal of Contraception and Reproductive Health Care Pub Date : 2024-12-01 Epub Date: 2024-08-21 DOI: 10.1080/13625187.2024.2387648
Erdenetuya Bolormaa, Taemi Kim, Eunson Gwak, Seung-Ah Choe, Adriane Martin Hilber
{"title":"Neighbourhood environment and early menarche among adolescent girls of five countries.","authors":"Erdenetuya Bolormaa, Taemi Kim, Eunson Gwak, Seung-Ah Choe, Adriane Martin Hilber","doi":"10.1080/13625187.2024.2387648","DOIUrl":"10.1080/13625187.2024.2387648","url":null,"abstract":"<p><strong>Introduction: </strong>We aim to investigate the relationship between individuals' perceptions of their neighbourhood environment and early menarche.</p><p><strong>Methods: </strong>This was a retrospective cohort study of 7,486 girls of Ethiopia, India, South Korea, the United Kingdom (UK), and the United States (US), born in 1997-2011 was analysed. Early menarche was defined as being below the 10th to 20th percentiles in each cohort, considering the varying distributions across countries. Perceived neighbourhood environments were assessed based on the responses for neighbourhood pollution, safety, and recreational facilities. We calculated the relative risk (RR) of early menarche for unfavourable environment.</p><p><strong>Results: </strong>The mean age at menarche was lowest in South Korea (10.6 years) and highest in Ethiopia (13.7 years). Unfavourable environment was associated with higher risk of early menarche overall (RR = 1.34, 95% confidence interval [CI]:1.09-1.65) and each country (3.03, 95% CI: 1.15-7.96 in Ethiopia; 1.99, 95% CI: 0.97-4.10 in India, 1.23, 95% CI: 0.67-2.27 in Korea; 1.26, 95% CI: 0.96-1.64 in the UK). Specifically, pollution (1.29, 95% CI: 1.03-1.62) and low safety (1.19, 95% CI: 1.60-1.88) were associated with early menarche.</p><p><strong>Conclusions: </strong>Our finding highlights the potential role of perceived neighbourhood environment in the timing of puberty.</p>","PeriodicalId":50491,"journal":{"name":"European Journal of Contraception and Reproductive Health Care","volume":" ","pages":"263-268"},"PeriodicalIF":1.9,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142019421","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Virtual reality for the management of pain and anxiety during outpatient manual vacuum aspiration for miscarriage or incomplete abortion: a mixed methods trial. 在门诊人工真空吸引术治疗流产或不全流产过程中利用虚拟现实技术控制疼痛和焦虑:一项混合方法试验。
IF 1.9 4区 医学
European Journal of Contraception and Reproductive Health Care Pub Date : 2024-12-01 Epub Date: 2024-10-15 DOI: 10.1080/13625187.2024.2410838
Anna Alexandra McDougall, Eleanor Bard, Ora Jesner, Shereen Ibrahim, Schahrazed Rouabhi, Nandita Deo
{"title":"Virtual reality for the management of pain and anxiety during outpatient manual vacuum aspiration for miscarriage or incomplete abortion: a mixed methods trial.","authors":"Anna Alexandra McDougall, Eleanor Bard, Ora Jesner, Shereen Ibrahim, Schahrazed Rouabhi, Nandita Deo","doi":"10.1080/13625187.2024.2410838","DOIUrl":"10.1080/13625187.2024.2410838","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the efficacy and acceptability of virtual reality (VR) as a distraction technique in the management of acute pain and anxiety during outpatient uterine aspiration using a manual vacuum aspirator (MVA).</p><p><strong>Materials and methods: </strong>This mixed methods study included a prospective multi-centre randomised controlled trial and structured individual interviews. Of the 72 patients approached, 50 consenting, eligible participants were randomised to VR intervention (immersive video content 'The Forest of Serenity') or standard care during MVA for the management of miscarriage or incomplete abortion from July 2021-July 2022 across two university hospitals in London, UK. Expected and actual pain scores, and anxiety before and after the procedure were measured as numeric rating scores (0-10). Structured interviews were undertaken after the procedure in women randomised to VR. Statistical analysis of pain and anxiety scores were by intention-to-treat including all randomised participants, using Stata-12 software. Qualitative analysis was achieved by thematic analysis of transcribed interviews.</p><p><strong>Results: </strong>There was no significant difference in pain or anxiety scores reported by participants randomised to VR compared with standard care. Mean worst pain scores were 5.98 and 6.88 in the standard care and VR groups respectively (p-value 0.13), with corresponding anxiety scores at the end of the procedure 3.94 and 3.3 (p-value 0.57). Qualitative analysis from interviews was highly favourable from women randomised to VR with all participants reporting a positive experience. 90% (18/20) of participants reported that VR reduced their anxiety and 71% (15/21) stated that it helped to reduce or distract from their pain.</p><p><strong>Conclusion: </strong>While virtual reality did not decrease pain or anxiety scores during MVA, it is a feasible and acceptable option that may improve patient experience.</p>","PeriodicalId":50491,"journal":{"name":"European Journal of Contraception and Reproductive Health Care","volume":" ","pages":"298-304"},"PeriodicalIF":1.9,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142479717","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Medical termination of pregnancy: people's expectations and experiences in the Netherlands. 医疗终止妊娠:荷兰人的期望和经历。
IF 1.9 4区 医学
European Journal of Contraception and Reproductive Health Care Pub Date : 2024-12-01 Epub Date: 2024-08-21 DOI: 10.1080/13625187.2024.2385533
Daphne C Latour-Oldenhof, Sandra M A Dijkstra-Kersten, Eline W Dalmijn, Jildau Tuinhof, Sophie H Bolt
{"title":"Medical termination of pregnancy: people's expectations and experiences in the Netherlands.","authors":"Daphne C Latour-Oldenhof, Sandra M A Dijkstra-Kersten, Eline W Dalmijn, Jildau Tuinhof, Sophie H Bolt","doi":"10.1080/13625187.2024.2385533","DOIUrl":"10.1080/13625187.2024.2385533","url":null,"abstract":"<p><strong>Purpose: </strong>Annually, approximately 31,000 people experience a termination of pregnancy (TOP) in the Netherlands. In 2021, about one-third of them chose medical termination of pregnancy (MTOP). We explored experiences with MTOP and to what extent expectations, pain, and counselling in the clinic are associated with satisfaction with MTOP.</p><p><strong>Materials and methods: </strong>A retrospective cross-sectional study was conducted using an online questionnaire. We included 138 respondents, ≥16 years, who chose MTOP (September 2020-March 2022).</p><p><strong>Results: </strong>The majority of respondents experienced MTOP more positively than expected or as expected (67%). For 24%, the experience was more negative than expected. In the event of another TOP, half of these respondents would hesitate to choose or would not choose MTOP, mainly due to physical side effects. The majority of respondents (73%) would choose MTOP again. Their main motivation was self-determination during treatment. Respondents cited four key elements: pain, intensity of experience during and after treatment, blood loss, and duration. Correspondence between MTOP expectations and experiences was associated with satisfaction with MTOP, while pain and satisfaction with counselling were not.</p><p><strong>Conclusions: </strong>The majority of respondents were satisfied with MTOP and would choose the treatment again. Non-correspondence between expectations and experiences negatively affected satisfaction with MTOP. This highlights the importance of managing expectations by providing accessible information about the variety in expectations and experiences to patients with a focus on key elements of the experience.</p>","PeriodicalId":50491,"journal":{"name":"European Journal of Contraception and Reproductive Health Care","volume":" ","pages":"287-293"},"PeriodicalIF":1.9,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142019420","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A pioneer of hormonal contraception: Joseph W. Goldzieher. 激素避孕的先驱约瑟夫-W-戈尔齐埃
IF 1.9 4区 医学
European Journal of Contraception and Reproductive Health Care Pub Date : 2024-12-01 Epub Date: 2024-10-01 DOI: 10.1080/13625187.2024.2407084
Giuseppe Benagiano, Michele Shedlin
{"title":"A pioneer of hormonal contraception: Joseph W. Goldzieher.","authors":"Giuseppe Benagiano, Michele Shedlin","doi":"10.1080/13625187.2024.2407084","DOIUrl":"10.1080/13625187.2024.2407084","url":null,"abstract":"<p><p>On 19 July, 2024, at the age of almost 105 years, Joseph W. Goldzieher, the last survivor of the group of pioneers who created oral contraception, peacefully passed away. Here we briefly reconstruct the salient points in his long, productive life, and highlight his achievements in the development of hormonal contraception. His work is indissolubly enshrined in the complex history of hormonal contraception, from the first, fundamental observations, to the first clinical trials, both in the form of combined oestrogen-progestin oral pills and long-acting injectable contraceptives. After Pincus and his Group created an oral contraceptive containing an oestrogen and a progestin, Goldzieher was the second international scientist to conduct clinical trials of the new modality. He teamed-up with investigators in Mexico creating a fruitful, long-lasting collaboration. They produced evidence that ovulation inhibition could be achieved with all the progestins used at the time. Of importance, he was among the first to explore the possibility of using oestrogens to block ovulation, and developed the concept of sequential contraception. For all this lifetime of work, we believe he deserves to be named a 'giant in reproductive endocrinology'.</p>","PeriodicalId":50491,"journal":{"name":"European Journal of Contraception and Reproductive Health Care","volume":" ","pages":"259-262"},"PeriodicalIF":1.9,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142331650","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The use of a pill containing ethinylestradiol-norgestimate improves female sexuality despite the decrease in circulating androgen: Correspondence. 使用含有炔雌醇-炔诺酮的避孕药可提高女性的性能力,尽管循环中的雄激素有所减少:通讯。
IF 1.9 4区 医学
European Journal of Contraception and Reproductive Health Care Pub Date : 2024-10-01 Epub Date: 2024-08-07 DOI: 10.1080/13625187.2024.2380910
Hinpetch Daungsupawong, Viroj Wiwanitkit
{"title":"The use of a pill containing ethinylestradiol-norgestimate improves female sexuality despite the decrease in circulating androgen: Correspondence.","authors":"Hinpetch Daungsupawong, Viroj Wiwanitkit","doi":"10.1080/13625187.2024.2380910","DOIUrl":"10.1080/13625187.2024.2380910","url":null,"abstract":"","PeriodicalId":50491,"journal":{"name":"European Journal of Contraception and Reproductive Health Care","volume":" ","pages":"256"},"PeriodicalIF":1.9,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141898816","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Response to Daungsupawong and Wiwanitkit's Letter to the Editor. 对 Daungsupawong 和 Wiwanitkit 致编辑的信的回应。
IF 1.9 4区 医学
European Journal of Contraception and Reproductive Health Care Pub Date : 2024-10-01 Epub Date: 2024-08-07 DOI: 10.1080/13625187.2024.2381392
Maurizio Guida, Luciano Quercitelli, Pasquale De Franciscis, Mariano Fiorenza, Alice Sgandurra, Antonio La Marca, Giovanni Grandi
{"title":"Response to Daungsupawong and Wiwanitkit's Letter to the Editor.","authors":"Maurizio Guida, Luciano Quercitelli, Pasquale De Franciscis, Mariano Fiorenza, Alice Sgandurra, Antonio La Marca, Giovanni Grandi","doi":"10.1080/13625187.2024.2381392","DOIUrl":"10.1080/13625187.2024.2381392","url":null,"abstract":"","PeriodicalId":50491,"journal":{"name":"European Journal of Contraception and Reproductive Health Care","volume":" ","pages":"257"},"PeriodicalIF":1.9,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141898814","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The impact of using the levonorgestrel-releasing intrauterine device on the incidence of acne in adolescents and young women. 使用左炔诺孕酮释放宫内节育器对青少年和年轻女性痤疮发病率的影响。
IF 1.9 4区 医学
European Journal of Contraception and Reproductive Health Care Pub Date : 2024-10-01 Epub Date: 2024-08-07 DOI: 10.1080/13625187.2024.2379363
Elaine Cristina Fontes de Oliveira, Janaína Campos Senra, Ana Luiza Lunardi Rocha
{"title":"The impact of using the levonorgestrel-releasing intrauterine device on the incidence of acne in adolescents and young women.","authors":"Elaine Cristina Fontes de Oliveira, Janaína Campos Senra, Ana Luiza Lunardi Rocha","doi":"10.1080/13625187.2024.2379363","DOIUrl":"10.1080/13625187.2024.2379363","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the impact of levonorgestrel-releasing intrauterine device (LNG-IUD) use on the incidence of acne in adolescents and young women.</p><p><strong>Methods: </strong>A narrative review was conducted in PubMed, Embase, Cochrane, and SciELO assessing the incidence of acne in adolescents and young women using LNG-IUD (13.5, or 19.5 mg, or 52 mg). Cohort, cross-sectional studies, clinical trials, and meta-analyses were included, without a date limit. Studies that didn't evaluate women in the age of interest were excluded. Only articles in English were selected.</p><p><strong>Results: </strong>Nine articles were included in this narrative review. Only clinical trials, cohort studies, and cross-sectional studies were evaluated. Two cross-sectional studies evaluated the incidence of acne in women using any contraceptive methods, with the incidence of acne being 36% in women aged 17 to 47 using LNG-IUD in one study. In another study, acne incidence ranged from 2 to 8% in women using any contraceptive methods, with higher rates in younger women and LNG-IUD users. The incidence of acne varies and participants between 16 to 35 years were more likely to report new acne or worsening of pre-existing acne. In a prospective cohort study of women between 16 and 24 years, acne was a common adverse effect, with 44% in the first year.</p><p><strong>Conclusion: </strong>The data indicate variability in the incidence of acne among LNG-IUD users, with a higher prevalence observed in younger women. Further research should focus on the effects of LNG-IUD on acne in young populations, with rigorous study designs and consideration of previous contraceptive use.</p>","PeriodicalId":50491,"journal":{"name":"European Journal of Contraception and Reproductive Health Care","volume":" ","pages":"233-238"},"PeriodicalIF":1.9,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141898815","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Inhibition ratio (I.R.) and transformation index (T.I.): new indexes to compare the effectiveness and clinical behaviour of modern progestin-only pills (POP). 抑制比(I.R.)和转化指数(T.I.):比较现代纯孕激素药片(POP)有效性和临床表现的新指标。
IF 1.9 4区 医学
European Journal of Contraception and Reproductive Health Care Pub Date : 2024-10-01 Epub Date: 2024-07-11 DOI: 10.1080/13625187.2024.2375285
Giovanni Grandi, Marta Barretta, Lia Feliciello, Michele Vignali, Antonio La Marca
{"title":"Inhibition ratio (I.R.) and transformation index (T.I.): new indexes to compare the effectiveness and clinical behaviour of modern progestin-only pills (POP).","authors":"Giovanni Grandi, Marta Barretta, Lia Feliciello, Michele Vignali, Antonio La Marca","doi":"10.1080/13625187.2024.2375285","DOIUrl":"10.1080/13625187.2024.2375285","url":null,"abstract":"<p><p>Progestin-only pills (POPs) have emerged as a crucial contraceptive option for women, particularly those contraindicated to oestrogens. This opinion paper introduces two new indices, the Inhibition Ratio (I.R.) (cyclical and daily) and the Transformation Index (T.I.), to evaluate and compare the efficacy and clinical behaviour of modern POPs. The I.R. quantifies the ratio between the progestin dosage in a POP and the minimum dose required to inhibit ovarian function, providing insights into contraceptive efficacy. The T.I., on the other hand, assesses its clinical impact by considering the ratio between the total progestin dose and the dose required to induce endometrial luteinising changes. Both indices thus offer valuable tools for comparing progestins even at significantly different dosages and regimens, providing information on clinical characteristics and drug effects. The newest formulations of POPs (Desogestrel 28 and Drospirenone 24 + 4) have demonstrated higher I.R. and T.I. in comparison to older versions, indicating significant improvements in contraceptive efficacy and clinical impact with better menstrual cycle control. We believe that using these indices will ensure a more informed and personalised choice of progestin not only for contraceptive purposes but also for therapeutic use in gynaecology. The future goal is to develop other progestins with even more advantageous I.R. and T.I., ensuring the best contraceptive efficacy with fewer side effects, even in women at risk (obese, etc.).</p>","PeriodicalId":50491,"journal":{"name":"European Journal of Contraception and Reproductive Health Care","volume":" ","pages":"189-192"},"PeriodicalIF":1.9,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141581402","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cost-effectiveness analysis of levonorgestrel-releasing intrauterine system (LNG-IUS) 52 mg versus other long-acting reversible contraceptives for contraception in Spain. 西班牙用于避孕的 52 毫克左炔诺孕酮释放宫内节育器 (LNG-IUS) 与其他长效可逆避孕药的成本效益分析。
IF 1.9 4区 医学
European Journal of Contraception and Reproductive Health Care Pub Date : 2024-10-01 Epub Date: 2024-07-11 DOI: 10.1080/13625187.2024.2369843
José C Quílez Conde, Inmaculada Parra Ribes, Josep Perelló-Capo, Paloma Lobo Abascal, Ignacio Cristóbal García, Mercedes Andeyro García, José Gutiérrez Alés, Mercedes Herrero Conde, Joan Rius Tarruella, Belén Espinós Lafuente
{"title":"Cost-effectiveness analysis of levonorgestrel-releasing intrauterine system (LNG-IUS) 52 mg versus other long-acting reversible contraceptives for contraception in Spain.","authors":"José C Quílez Conde, Inmaculada Parra Ribes, Josep Perelló-Capo, Paloma Lobo Abascal, Ignacio Cristóbal García, Mercedes Andeyro García, José Gutiérrez Alés, Mercedes Herrero Conde, Joan Rius Tarruella, Belén Espinós Lafuente","doi":"10.1080/13625187.2024.2369843","DOIUrl":"10.1080/13625187.2024.2369843","url":null,"abstract":"<p><strong>Introduction: </strong>Condoms and combined oral contraceptive pills are widely used in Spain with high failure rates. Long-Acting Reversible Contraceptive (LARC) methods offer better efficacy and adherence and reduce unintended pregnancies (UP) compared with short-acting reversible contraceptive (SARC) methods.</p><p><strong>Objective: </strong>To assess the cost-effectiveness of LNG-IUS 52 mg (Mirena<sup>®</sup>) versus other LARC for contraception in Spain.</p><p><strong>Materials and methods: </strong>A Markov model with annual cycles and an eight-year time horizon was developed from the Spanish national healthcare system (NHS) perspective, considering costs for contraceptive method acquisition, health care resources (HCR) and UP. Effectiveness was based on failure and discontinuation rates. Sensitivity analyses were performed to test the model's robustness.</p><p><strong>Results: </strong>LNG-IUS 52 mg (Mirena<sup>®</sup>) resulted in lower costs and fewer UP versus LNG-IUS 13.5 mg (Jaydess<sup>®</sup>), Implant (Implanon<sup>®</sup>) and Copper IUD. LNG-IUS 52 mg (Levosert<sup>®</sup>) prevented the same UP events at a higher cost. LNG-IUS 19.5 mg (Kyleena<sup>®</sup>) was the most effective option, due to a lower discontinuation rate.</p><p><strong>Conclusions: </strong>LNG-IUS 52 mg (Mirena<sup>®</sup>) is the least costly LARC, driven by lower acquisition costs and reduced HCR utilisation. Increasing LNG-IUS 52 mg (Mirena<sup>®</sup>) uptake in contraception could generate further cost savings for the Spanish NHS and reduce economic burden of UP.</p>","PeriodicalId":50491,"journal":{"name":"European Journal of Contraception and Reproductive Health Care","volume":" ","pages":"224-232"},"PeriodicalIF":1.9,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141581401","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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