European Journal of Internal Medicine最新文献

{"title":"Promoting women's careers in life science and medicine: A position paper from the “International Women in Intensive Medicine” network","authors":"Olfa Hamzaoui ,&nbsp;Florence Boissier ,&nbsp;Carla Teixera ,&nbsp;Luciana Mascia ,&nbsp;Irene Aragao ,&nbsp;Sahar Bahrami ,&nbsp;Maria Cruz Martin Delgado ,&nbsp;Jannicke Mellin-Oslen ,&nbsp;Jordi Rello ,&nbsp;Francesca Rubulotta ,&nbsp;iWIN network members in annex 1","doi":"10.1016/j.ejim.2025.02.006","DOIUrl":"10.1016/j.ejim.2025.02.006","url":null,"abstract":"<div><h3>Background</h3><div>Women remain underrepresented and undervalued in leadership roles within scientific and healthcare disciplines, facing persistent gender discrimination and various professional barriers.</div></div><div><h3>Methods</h3><div>This paper presents the main findings and recommendations from the 2023 International Women in Intensive and Critical Care Network (iWIN) Roundtable, which convened a diverse group of experts to discuss equity and inclusiveness for women in their careers.</div></div><div><h3>Results</h3><div>The discussion highlighted three critical themes: social barriers (such as maternal identity and cultural pressures), the need for resilience-building through mentorship/sponsorship and support networks; and practical challenges, including childcare and limited career guidance. To address these issues, the panel proposed developing and empowering women's networks, emphasizing their role in promoting gender equality, fostering diversity, and supporting professional development. A key recommendation is the creation of a digital platform to increase the visibility of women scientists and connect them with opportunities for engagement and leadership. Additionally, the paper underscores the importance of institutional support for flexible work arrangements, mentorship programs, and leadership development initiatives.</div></div><div><h3>Conclusions</h3><div>The proposed strategies aim to not only advance the careers of women in science and healthcare but also to challenge and reshape the stereotypes surrounding who can be a scientist. By providing practical tools and fostering a culture of inclusiveness, these recommendations have the potential to significantly impact the representation of women in these fields and contribute to broader societal change.</div></div>","PeriodicalId":50485,"journal":{"name":"European Journal of Internal Medicine","volume":"134 ","pages":"Pages 89-95"},"PeriodicalIF":5.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143434311","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The emperor's new clothes and the case of vitamin D and cardiovascular risk. A few thoughts after the guidelines of the American Society of Endocrinology","authors":"Claudio Cimminiello","doi":"10.1016/j.ejim.2025.02.010","DOIUrl":"10.1016/j.ejim.2025.02.010","url":null,"abstract":"","PeriodicalId":50485,"journal":{"name":"European Journal of Internal Medicine","volume":"134 ","pages":"Pages 25-27"},"PeriodicalIF":5.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143426441","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of cardiovascular, thromboembolic and cancer risk in patients eligible for treatment with Janus Kinase inhibitors: The JAK-ERA multidisciplinary consensus","authors":"Lorenzo Dagna ,&nbsp;Alessia Alunno ,&nbsp;Nicola Farina ,&nbsp;Giancarlo Agnelli ,&nbsp;Claudio Borghi ,&nbsp;Roberto Caporali ,&nbsp;Antonio Costanzo ,&nbsp;Silvio Danese ,&nbsp;Filippo De Braud ,&nbsp;Gian Domenico Sebastiani ,&nbsp;Carlo Maurizio Montecucco","doi":"10.1016/j.ejim.2025.02.021","DOIUrl":"10.1016/j.ejim.2025.02.021","url":null,"abstract":"<div><h3>Introduction</h3><div>JAK inhibitors (JAKi) have emerged as effective treatments for chronic inflammatory diseases, including gastrointestinal, dermatological, and rheumatological conditions. Despite their efficacy, concerns about their safety profile necessitate a comprehensive framework for their optimal use. This study aimed to establish an expert consensus (the JAK-ERA [Janus Kinase-inhibitors Evidence-based Risk Analysis] Multidisciplinary Expert Consensus) on the principles guiding JAKi therapy to maximize therapeutic benefits while mitigating risks.</div></div><div><h3>Methods</h3><div>A Delphi method was employed, gathering opinions from experts across multiple disciplines. This iterative process involved rounds of surveys and feedbacks to synthesize diverse expert knowledge into a cohesive set of principles and consensus statements. The multidisciplinary panel included specialists in cardiology, oncology, hematology, gastroenterology, dermatology, and rheumatology.</div></div><div><h3>Results</h3><div>A total of 6 overarching principles and 13 expert consensus statements were developed. The percentage of agreement ranged between 78 and 100 %. The principles highlight the importance of rapid intervention to prevent complications and alleviate psychological burdens. Detailed risk assessments for cardiovascular (CV), thromboembolic, and cancer risks were deemed essential. Recommendations included using validated tools for CV risk evaluation, comprehensive thromboembolic risk assessment, and routine cancer screenings based on standard protocols. Multidisciplinary collaboration was stressed to ensure precise risk management and optimal therapeutic outcomes.</div></div><div><h3>Conclusion</h3><div>The consensus provides a structured approach to JAKi therapy, balancing efficacy with safety considerations. The overarching principles and expert consensus statements offer a robust framework for clinical practice, ensuring that JAKi use is tailored to individual patient profiles, thereby enhancing outcomes and minimizing risks. Ongoing validation through prospective studies and real-world data is essential to further refine these recommendations.</div></div>","PeriodicalId":50485,"journal":{"name":"European Journal of Internal Medicine","volume":"134 ","pages":"Pages 114-118"},"PeriodicalIF":5.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143469906","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Refining metabolic health assessment in inflammatory bowel disease risk prediction","authors":"Yinfang Wu,&nbsp;Weixing Xu","doi":"10.1016/j.ejim.2024.10.020","DOIUrl":"10.1016/j.ejim.2024.10.020","url":null,"abstract":"","PeriodicalId":50485,"journal":{"name":"European Journal of Internal Medicine","volume":"134 ","pages":"Pages 148-149"},"PeriodicalIF":5.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142548728","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"What is the impact of thiamine deficiency on cognitive function in patients with alcohol use disorder? – A systematic review","authors":"Joana Teixeira ,&nbsp;Inês Pereira ,&nbsp;Miguel Castanho ,&nbsp;Frederico Simões do Couto","doi":"10.1016/j.ejim.2025.01.008","DOIUrl":"10.1016/j.ejim.2025.01.008","url":null,"abstract":"<div><div>Cognitive impairments are frequently observed in patients with Alcohol Use Disorder (AUD). Thiamine deficiency is often found in AUD patients and has been suggested as a possible cause of cognitive impairments. While thiamine deficiency is not consistently present in all AUD patients with cognitive deficits, thiamine is traditionally prescribed to patients with AUD to treat or prevent cognitive impairment.</div><div>To better understand the relationship between thiamine levels and cognitive impairments in AUD patients, we conducted a systematic literature review following the Cochrane guidelines and adhering to the PRISMA-P framework. Additionally, this review is registered in PROSPERO under the reference CRD42024522058. Our research question was: “what is the impact of thiamine deficiency on cognitive function in patients with AUD?”.</div><div>The studies included in this review assessed thiamine levels in AUD patients and found values at or above the threshold for many measures of thiamine deficiency. Despite baseline thiamine levels being above the cutoff for deficiency in these studies, many still identified a correlation between thiamine levels and cognitive function with lower thiamine levels associated with cognitive impairments in AUD patients.</div><div>This review indicates that there is a relationship between thiamine levels and cognitive function in AUD patients, even in the absence of thiamine deficit. The cognitive domains particularly affected are visuospatial/executive ability, abstraction, attention, verbal fluency, and memory scores, notably delayed memory. Additionally, studies have demonstrated that thiamine supplementation in AUD patients, even in the absence of thiamine deficit, leads to improvements in cognitive function.</div></div>","PeriodicalId":50485,"journal":{"name":"European Journal of Internal Medicine","volume":"134 ","pages":"Pages 59-65"},"PeriodicalIF":5.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143015581","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The misalignment between chronotype and sleep time: Friend or foe?","authors":"Eleonora Tobaldini ,&nbsp;Angelica Carandina ,&nbsp;Nicola Montano","doi":"10.1016/j.ejim.2025.02.035","DOIUrl":"10.1016/j.ejim.2025.02.035","url":null,"abstract":"","PeriodicalId":50485,"journal":{"name":"European Journal of Internal Medicine","volume":"134 ","pages":"Pages 35-37"},"PeriodicalIF":5.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143558706","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Frailty, disability and patient-reported outcomes in apixaban users","authors":"Stefano Fumagalli ,&nbsp;Giuseppe Di Pasquale ,&nbsp;Giulio Molon ,&nbsp;Giancarlo Agnelli ,&nbsp;Niccolò Marchionni ,&nbsp;APULEIO Study Investigators","doi":"10.1016/j.ejim.2025.01.022","DOIUrl":"10.1016/j.ejim.2025.01.022","url":null,"abstract":"","PeriodicalId":50485,"journal":{"name":"European Journal of Internal Medicine","volume":"134 ","pages":"Pages 163-165"},"PeriodicalIF":5.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143076283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reevaluating hypoxia and cancer as determinants of prognosis in COPD and Takotsubo syndrome. Author's reply","authors":"Luca Arcari ,&nbsp;Giacomo Tini ,&nbsp;Beatrice Musumeci ,&nbsp;Emanuele Barbato ,&nbsp;Luca Cacciotti","doi":"10.1016/j.ejim.2025.02.012","DOIUrl":"10.1016/j.ejim.2025.02.012","url":null,"abstract":"","PeriodicalId":50485,"journal":{"name":"European Journal of Internal Medicine","volume":"134 ","pages":"Pages 143-144"},"PeriodicalIF":5.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143384067","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Catheter ablation of atrial fibrillation in older patients: The need for a comprehensive evaluation and management","authors":"Mario Bo ,&nbsp;Marco Proietti ,&nbsp;Roberto Presta","doi":"10.1016/j.ejim.2025.02.030","DOIUrl":"10.1016/j.ejim.2025.02.030","url":null,"abstract":"","PeriodicalId":50485,"journal":{"name":"European Journal of Internal Medicine","volume":"134 ","pages":"Pages 38-40"},"PeriodicalIF":5.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143537984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Enhancing the understanding of hyperhomocysteinemia and MASLD: Addressing methodological limitations and future directions","authors":"Yefang Liu ,&nbsp;Tingting Tan ,&nbsp;Helei Yu ,&nbsp;Zeping Chen","doi":"10.1016/j.ejim.2024.12.008","DOIUrl":"10.1016/j.ejim.2024.12.008","url":null,"abstract":"","PeriodicalId":50485,"journal":{"name":"European Journal of Internal Medicine","volume":"134 ","pages":"Pages 160-161"},"PeriodicalIF":5.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142808372","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}