European Journal of Internal Medicine最新文献_第3页

Non cardiovascular comorbidities in Heart Failure. An updated position paper from the Heart Failure Working Group of the Italian Society of Cardiology (SIC) 心力衰竭的非心血管合并症。意大利心脏病学会（SIC）心力衰竭工作组的最新立场文件。

IF 6.1 2区医学

European Journal of Internal Medicine Pub Date : 2025-10-01 DOI: 10.1016/j.ejim.2025.106457

Michele Correale , Andrea Salzano , Lucia Tricarico , Antonio Cittadini , Giulia Crisci , Giuseppe Dattilo , Riccardo Maria Inciardi , Emiliano Fiori , Stefania Paolillo , Gaetano Ruocco , Angela Sciacqua , Paolo Severino , Valentina Mercurio , Piergiuseppe Agostoni , Francesco Barillà , Frank Lloyd Dini , Pasquale Perrone Filardi , Savina Nodari , Alberto Palazzuoli , Italian Society of Cardiology (ISC) Working Group on Heart Failure

{"title":"Non cardiovascular comorbidities in Heart Failure. An updated position paper from the Heart Failure Working Group of the Italian Society of Cardiology (SIC)","authors":"Michele Correale , Andrea Salzano , Lucia Tricarico , Antonio Cittadini , Giulia Crisci , Giuseppe Dattilo , Riccardo Maria Inciardi , Emiliano Fiori , Stefania Paolillo , Gaetano Ruocco , Angela Sciacqua , Paolo Severino , Valentina Mercurio , Piergiuseppe Agostoni , Francesco Barillà , Frank Lloyd Dini , Pasquale Perrone Filardi , Savina Nodari , Alberto Palazzuoli , Italian Society of Cardiology (ISC) Working Group on Heart Failure","doi":"10.1016/j.ejim.2025.106457","DOIUrl":"10.1016/j.ejim.2025.106457","url":null,"abstract":"<div><div>Heart Failure (HF) is frequently associated with various non cardiovascular (CV) comorbidities significantly impacting HF prognosis. Indeed, the simultaneous presence of multiple diseases leads to an increased vulnerability, with frailty occurrence. This status implies poor quality of life and increased adverse events rate in terms of hospitalization and mortality. Therefore, the most recent trials and observational studies indicate non-CV comorbidities as new targets for novel management strategies and drugs; however, there is still the need to better understand the pathophysiology of non-CV comorbidities and the possible interplay between non-CV comorbidities and HF. Additionally, metabolic, and multiple organ diseases reduce the use and the achievement of targeted doses of HF Guideline-directed medical therapy (GDMT), due to potential adverse effects, exposing patients to further clinical events. Finally, non-CV comorbidities burden demonstrated different prevalence and prognostic impact according to HF phenotypes, impacting on the disease progression. Therefore, in order to provide physicians and researchers engaged in the “fight against heart failure” an updated practice guide, the Working Group on Heart Failure of the Italian Society of Cardiology (ISC) offers a revised manifesto on the relationship between non-CV comorbidities and HF.</div></div>","PeriodicalId":50485,"journal":{"name":"European Journal of Internal Medicine","volume":"140 ","pages":"Article 106457"},"PeriodicalIF":6.1,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144977173","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The role of the hospitalist in Europe: results by EFIM multimorbidity working group survey 欧洲医院医生的作用：EFIM多病工作组调查的结果。

IF 6.1 2区医学

European Journal of Internal Medicine Pub Date : 2025-10-01 DOI: 10.1016/j.ejim.2025.05.006

Ombretta Para , Flora Kisuule , Arántzazu Álvarez-de Arcaya , Antonio Gonzalez Fernandez , Maximo Bernabeu-Wittel

引用次数: 0

Gastroenteritis caused by Shiga-toxigenic Escherichia coli. Are antibiotics always prohibited in this disease? 由产志贺毒素大肠杆菌引起的肠胃炎。这种疾病是否总是禁止使用抗生素？

IF 6.1 2区医学

European Journal of Internal Medicine Pub Date : 2025-10-01 DOI: 10.1016/j.ejim.2025.05.035

Juan Gabriel Sánchez-Cano , Ana Belén Mecina-Gutiérrez , Carolina Campelo-Gutiérrez , María Velasco-Arribas , Leonor Moreno-Núñez

引用次数: 0

Neurologic and psychiatric disorders following correction of profound hyponatremia - A cohort study 深度低钠血症纠正后的神经和精神疾病-一项队列研究。

IF 6.1 2区医学

European Journal of Internal Medicine Pub Date : 2025-10-01 DOI: 10.1016/j.ejim.2025.06.023

Henrik Falhammar , Mikael Andersson Franko , Jonatan D. Lindh , Jakob Skov , Buster Mannheimer

{"title":"Neurologic and psychiatric disorders following correction of profound hyponatremia - A cohort study","authors":"Henrik Falhammar , Mikael Andersson Franko , Jonatan D. Lindh , Jakob Skov , Buster Mannheimer","doi":"10.1016/j.ejim.2025.06.023","DOIUrl":"10.1016/j.ejim.2025.06.023","url":null,"abstract":"<div><h3>Background</h3><div>Rapid correction of profound hyponatremia (serum sodium <125 mmol/L) has been associated with osmotic demyelination syndrome (ODS) but this has been challenged. Potential associations with other neurological and psychiatric diseases have not been studied.</div></div><div><h3>Methods</h3><div>The basis of this study was the Stockholm Sodium Cohort, a laboratory data repository covering inhabitants of the Stockholm Region who had a sodium concentration analyzed (2005–2018, <em>n</em> = 1632,249). Patients admitted with profound hyponatremia for the first time during the study period where sodium correction rates during the first 24 h could be calculated were included. Sodium correction ≤8 and >8 mmol/L/24 h was compared.</div></div><div><h3>Results</h3><div>Hospitalization with profound hyponatremia occurred in 7623 individuals, 3199 (42.0 %) were males, and the median age was 70 years (IQR 59–80 years). Alcohol misuse was present in 18.3 %, a neurological and/or psychiatric disease in 52.4 % and hypokalemia in 27.9 %. The recommended correction rate ≤8 mmol/L/24 h was adhered to in 3985 (52.3 %) patients. Seven patients (0.09 %) were diagnosed with ODS, six had a correction rate >8 mmol/L/24 h (compared to 1 patient with a correction rate ≤8 mmol/L, <em>P</em> = 0.0441). The risk of new neurological or psychiatric diseases did not differ significantly between those with a correction rate ≤8 mmol/L/24 h and those above in the fully adjusted model (adjusted hazard ratio 1.02 95 %CI 0.89–1.17)) nor in the subgroups.</div></div><div><h3>Conclusions</h3><div>ODS was rare, however, mainly associated with rapid correction. Consequently, slow correction may be preferable.</div></div>","PeriodicalId":50485,"journal":{"name":"European Journal of Internal Medicine","volume":"140 ","pages":"Article 106394"},"PeriodicalIF":6.1,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144509256","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Unaddressed limitations in triglyceride management among CHD patients: A call for methodological rigor 冠心病患者甘油三酯管理未解决的局限性：对方法严谨性的呼吁。

IF 6.1 2区医学

European Journal of Internal Medicine Pub Date : 2025-10-01 DOI: 10.1016/j.ejim.2025.106490

Kunal Mahajan, Jai Bharat Sharma, Surender Himral, Shivali Sandal

引用次数: 0

Diagnostic contribution of minor salivary glands biopsy in clinical practice 小唾液腺活检在临床中的诊断价值。

IF 6.1 2区医学

European Journal of Internal Medicine Pub Date : 2025-10-01 DOI: 10.1016/j.ejim.2025.05.005

Marion Mauclin , Anh-Tuan Nguyen , Hubert Nielly , Hélène Vanquaethem , Weniko Caré

引用次数: 0

Artificial intelligence and the electrocardiogram: A modern renaissance 人工智能和心电图：现代复兴。

IF 6.1 2区医学

European Journal of Internal Medicine Pub Date : 2025-10-01 DOI: 10.1016/j.ejim.2025.04.036

Stefano Palermi , Marco Vecchiato , Fu Siong Ng , Zachi Attia , Youngjin Cho , Matteo Anselmino , Gaetano Maria De Ferrari , Andrea Saglietto

{"title":"Artificial intelligence and the electrocardiogram: A modern renaissance","authors":"Stefano Palermi , Marco Vecchiato , Fu Siong Ng , Zachi Attia , Youngjin Cho , Matteo Anselmino , Gaetano Maria De Ferrari , Andrea Saglietto","doi":"10.1016/j.ejim.2025.04.036","DOIUrl":"10.1016/j.ejim.2025.04.036","url":null,"abstract":"<div><div><span>Integrating Artificial Intelligence (AI) with electrocardiograms (ECG) represents a transformative shift in cardiovascular medicine, marking a modern renaissance of this traditional diagnostic technique. This article explores recent advancements in AI-enhanced ECG technologies, highlighting their potential to improve diagnostic accuracy, predict cardiovascular events, and enable personalized patient care. AI-driven ECG interpretation has demonstrated groundbreaking capabilities in the field of both structural and electrical heart diseases. Furthermore, deep learning techniques have expanded diagnostic capabilities by identifying subtle ECG patterns invisible to the human eye, improving the detection of several cardiac disorders. The increasing integration of AI-ECG into wearable technologies extends </span>cardiac monitoring beyond conventional clinical settings, providing continuous, real-time health assessment. Despite these advancements, the widespread adoption of AI-ECG faces several challenges, such as the need for high-quality training data, ensuring algorithm generalizability across diverse populations, addressing bias in model training, and meeting critical regulatory and ethical standards. Moreover, concerns regarding explainability, physician deskilling, legal accountability, and the lack of high-quality studies proving improved patient outcomes remain key obstacles. By enhancing precision in detecting cardiovascular conditions and expanding access to proactive heart health monitoring, AI-enhanced ECG technology holds immense potential for reshaping cardiovascular diagnostics and management, always aiming at maintaining physician trust and patient safety.</div></div>","PeriodicalId":50485,"journal":{"name":"European Journal of Internal Medicine","volume":"140 ","pages":"Article 106329"},"PeriodicalIF":6.1,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144210108","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Classification of coronary syndromes: Need for refinement? 冠状动脉综合征的分类：需要改进吗？

IF 6.1 2区医学

European Journal of Internal Medicine Pub Date : 2025-10-01 DOI: 10.1016/j.ejim.2025.106444

Andrea Rubboli

引用次数: 0

Trends in cardiovascular disease-related mortality among adults with sleep apnea in the United States from 1999-2020 1999-2020年美国成人睡眠呼吸暂停患者心血管疾病相关死亡率趋势

IF 6.1 2区医学

European Journal of Internal Medicine Pub Date : 2025-10-01 DOI: 10.1016/j.ejim.2025.04.013

Usama Qamar , Siddharth Agarwal , Maaz Asif , Waleed Qamar , Zain Ul Abideen Asad

引用次数: 0

Real-world glucose-lowering strategies for managing glucocorticoid-induced diabetes in non-intensive hospital settings 在非重症医院环境中管理糖皮质激素诱导的糖尿病的实际降糖策略

IF 6.1 2区医学

European Journal of Internal Medicine Pub Date : 2025-10-01 DOI: 10.1016/j.ejim.2025.05.033

Michela Vergani , Matteo Conti , Alessia Lari , Federico Bertuzzi , Basilio Pintaudi

引用次数: 0