Experimental and Clinical Transplantation最新文献

{"title":"Attitude and Knowledge Toward Organ Donation among University Medical Students: A Cross-Sectional Study in Southwest Iran.","authors":"Leila Malekmakan, Nakisa Rasaei, Sahar Sanjarian, Abdalrhman Hammoud, Alireza Malek Makan, Aida Doostkam","doi":"10.6002/ect.2025.0159","DOIUrl":"https://doi.org/10.6002/ect.2025.0159","url":null,"abstract":"<p><strong>Objectives: </strong>We evaluated the knowledge, attitudes, and barriers surrounding organ donation among medical students in southwest Iran.</p><p><strong>Materials and methods: </strong>A questionnaire was prepared for this sociological and cross-sectional study. Our study included 136 student participants (mean age of 24.6 ± 2.3 years). Most students were men (55.1%) in year 7 of studies (23.5%) in Shiraz in southwestern Iran.</p><p><strong>Results: </strong>Among 136 participants, 86.6% (n = 118) indicated support for organ donation, 9.6% (n = 13) were uncertain, and 3.7% (n = 5) did not support organ donation. Few students (16.9%) understood the organ donation system. The awareness level of the country's current organ donation system among participants in different years of studies did not differ (P > .050). Almost 69.9% of the participants (n = 95) stated that doctors should promote organ donation to the general public.</p><p><strong>Conclusions: </strong>Health care professionals have a vital role in increasing the number of organ donors. Educational programs would enhance medical students' knowledge and attitudes about organ donation and transplantation. In addition to the influence of health care professionals, the support of the media and religious leaders should also be noted to boost organ donation.</p>","PeriodicalId":50467,"journal":{"name":"Experimental and Clinical Transplantation","volume":"23 12","pages":"778-783"},"PeriodicalIF":0.7,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146041946","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical Analysis of Posttransplant Lymphoproliferative Disorder After Liver Transplant.","authors":"Wenjing Wang, Min Tian, Yuanyuan Wang, Ding Wang, Ting Lin, Yuzhe Li, Bo Wang, Xufeng Zhang, Xiaogang Zhang, Bo Guo","doi":"10.6002/ect.2025.0225","DOIUrl":"https://doi.org/10.6002/ect.2025.0225","url":null,"abstract":"<p><strong>Objectives: </strong>Posttransplant lymphoproliferative disorder is a severe and potentially fatal complication after liver transplant, resulting from immunosuppression-driven uncontrolled lymphoid proliferation. In this study, we aimed to analyze the incidence, clinico-pathological characteristics, management, and outco-mes of posttransplant lymphoproliferative disorder in liver transplant recipients.</p><p><strong>Materials and methods: </strong>We conducted a retrospective analysis of 1288 patients who underwent liver transplant between January 2015 and December 2024. Among them, 8 recipients (0.62%) were diagnosed with posttransplant lymphoproliferative disorder based on histopathological and clinical criteria. Baseline characteristics, clinicopathological characteristics, management, and outcome data were collected and statistically evaluated.</p><p><strong>Results: </strong>Age at time of transplant was 55.5 years (range, 44-62 years), and posttransplant lymphoproliferative disorder was diagnosed at 10.5 months posttransplant (interquartile range, 7.5-28.5 mo; range, 5-44 mo). Clinical manifestations were diverse and nonspecific, with 6 having allograft involvement (75%) and 7 having detectable Epstein-Barr virus positivity (87.5%). Monomorphic B-cell posttransplant lymphoproliferative disorder (B-cell lymphomas and diffuse large B-cell lymphoma) was the most common subtype (87.5%). All recipients with posttransplant lymphoproliferative disorder received immunosuppression reduction or withdrawal. Three patients with diffuse large B-cell lymphoma-type received chemotherapy, 1 with central nervous system-type received rituximab plus cyclophosphamide, and 1 received rituximab combined with radiofrequency ablation for liver lesions. Of the 8 recipients, 3 had remission and 5 died due to sepsis complications and posttransplant lymphoproliferative disorder. Median time from diagnosis of posttransplant lymphoproliferative disorder to death was 2 months (range, 1.5-5.5 mo).</p><p><strong>Conclusions: </strong>Posttransplant lymphoproliferative disor-der, characterized by heterogeneous manifestations, remains a serious complication after liver transplant. Early diagnosis requires a combination of Epstein-Barr virus DNA monitoring and imaging. Definitive patho-logical diagnosis and classification are essential for guiding treatment strategies, including reduction of immunosuppression and rituximab-based chemotherapy.</p>","PeriodicalId":50467,"journal":{"name":"Experimental and Clinical Transplantation","volume":"23 12","pages":"802-810"},"PeriodicalIF":0.7,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146042003","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Liver Transplant in a Patient With Infrahepatic Interruption of the Inferior Vena Cava: A Case Report.","authors":"Mallika Datta, Yuzuru Sambommatsu, Jill Bruno, Vinay Kumaran, Daisuke Imai, Seung Duk Lee, Aamir A Khan, Amit Sharma, Adrian H Cotterell, David A Bruno","doi":"10.6002/ect.2025.0165","DOIUrl":"10.6002/ect.2025.0165","url":null,"abstract":"<p><p>Although infrahepatic inferior vena cava interruption has been reported in patients undergoing liver transplant, details on perioperative management are scarce. Here, we present a patient with a congenital inferior vena cava anomaly, characterized by infra-hepatic interruption of the inferior vena cava accom-panied by azygos continuation, who underwent orthotopic liver transplant. Patients with anomalies of the inferior vena cava require important considerations during preoperative, intraoperative, and postoperative phases of liver transplant. These considerations, which led to our patient having a good outcome that continued 2 years after transplant, are detailed in this report.</p>","PeriodicalId":50467,"journal":{"name":"Experimental and Clinical Transplantation","volume":"23 12","pages":"830-832"},"PeriodicalIF":0.7,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146042022","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Tumor-Bearing Kidneys as Potential Donors: A National Survey From the United Kingdom.","authors":"Farhad Janahi, Muhammad Zeeshan Aslam, Matthew Trail, Tim Brown, Ali Thwaini","doi":"10.6002/ect.2025.0138","DOIUrl":"https://doi.org/10.6002/ect.2025.0138","url":null,"abstract":"<p><strong>Objectives: </strong>Kidneys classified to be so-called tumor-bearing kidneys as potential donor kidneys typically involve small (<4 cm), low-grade renal tumors resected ex vivo. Kidney transplant remains the definitive treatment for end-stage renal disease, yet organ shortages persist worldwide. The use of kidneys with small, resectable renal tumors has been proposed as a strategy to expand the donor pool.</p><p><strong>Materials and methods: </strong>A national online survey was conducted from November to December 2019, targeting urologists, nephrologists, and transplant surgeons based in the United Kingdom. The aim was to assess clinician perspectives on the use of tumor-bearing kidneys as potential donor kidneys in selected patients with end-stage renal disease.</p><p><strong>Results: </strong>Of 230 clinicians approached, 108 responded (47%). Support for the use of tumor-bearing kidneys as potential donor kidneys was highest among transplant surgeons (100%), followed by urologists (71%) and nephrologists (54%).</p><p><strong>Conclusions: </strong>The findings demonstrate broad support among United Kingdom clinicians for the selective use of tumor-bearing kidneys as potential donor kidneys. Despite ethical and logistical concerns, this consensus may justify the initiation of formal trials and the development of centralized protocols to increase organ availability.</p>","PeriodicalId":50467,"journal":{"name":"Experimental and Clinical Transplantation","volume":"23 12","pages":"784-786"},"PeriodicalIF":0.7,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146042049","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Short-Term Semaglutide Improves Safety in High Body Weight Recipients Undergoing Living Donor Liver Transplant: A Case Report.","authors":"Ssu-Min Cheng, Yin Lai, Ruo-Yi Huang, Wei-Chen Lee, Chen-Fang Lee, Ting-Jung Wu","doi":"10.6002/ect.2025.0244","DOIUrl":"10.6002/ect.2025.0244","url":null,"abstract":"<p><p>Living donor liver transplant has recently become increasingly important as a solution to the shortage of deceased donor livers. The success of adult-to-adult living donor liver transplant depends on achievement of an appropriate graft-to-recipient weight ratio to prevent complications like small-for-size syndrome. This case report describes the use of oral semaglutide, a glucagon-like peptide-1 receptor agonist, to faci-litate pretransplant weight loss in an obese patient (body mass index 39.1, in kg/m2) undergoing living donor liver transplant. The patient experienced a significant weight loss of 10 kg during a period of 19 days with semaglutide treatment, which improved the graft-to-recipient weight ratio (from 0.66% to 0.786%) and resulted in an uneventful living donor liver transplant procedure with no postoperative issues. This case marks the first documented case of using semaglutide for pretransplant weight loss in liver transplant recipients, highlighting its potential to improve surgical outcomes for overweight patients awaiting transplant.</p>","PeriodicalId":50467,"journal":{"name":"Experimental and Clinical Transplantation","volume":"23 12","pages":"838-841"},"PeriodicalIF":0.7,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146042051","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lipid Droplet Dynamics in Hepatocytes During Lipotoxic Stress: Transition From Fatty Liver to Liver Transplantation.","authors":"H Pinar Baysan Cebi, Deniz Ekin Erbas, Neslihan Bascil Tutuncu, Yaprak Yalcin, Hasibe Verdi, F Figen Kaymaz, F Belgin Atac","doi":"10.6002/ect.2025.0003","DOIUrl":"https://doi.org/10.6002/ect.2025.0003","url":null,"abstract":"<p><strong>Objectives: </strong>Metabolic dysfunction-associated steatotic liver disease, the most common chronic liver disease worldwide, is a major cause of end-stage liver failure requiring transplant. Its hallmark, free fatty acid accumulation in hepatocytes, leads to lipotoxicity. We examined lipid droplet and mitochondrial changes in HepG2 cells under lipotoxic conditions.</p><p><strong>Materials and methods: </strong>Lipotoxic stress was induced in HepG2 cells (ATCC HB8065) by treating cells with 1 mM palmitic acid. We studied cells at 0, 12, and 24 hours. Cells were fixed in 2.5% glutaraldehyde (pH 7.4), postfixed with 1% osmium tetroxide in 0.1 M phosphate buffer, dehydrated in ethanol, and embedded in Araldite/Epon812 resin. We prepared sections by using a microtome. Semi-thin sections were stained with methylene blue-azure II and analyzed with light microscopy. Ultrathin sections were double-stained with uranyl acetate and lead citrate and examined with a JEOL-JEM 1400 electron microscope with a charge-coupled device camera. We observed substantial mitochondrial and cellular alterations associated with palmitic acid-induced lipotoxic stress.</p><p><strong>Results: </strong>When morphological changes in HepG2 cells were analyzed at 0, 12, and 24 hours, treatment with palmitic acid caused substantial stress in HepG2 cells, with the most noticeable effects observed at 24 hours. Morphological analysis indicated increased lipid vacuoles by 12 hours posttreatment compared with at 0 hours (baseline). Structural changes in mitochondria, such as enlargement and elongation, were also noted. After 24 hours, the number of mitochondria and lipid vacuoles had further increased, showing clear signs of mitophagy, indicating activation of protective hepatocellular mechanisms to address organelle stress caused by lipotoxicity.</p><p><strong>Conclusions: </strong>Palmitic acid-induced lipotoxicity activates mitophagy, which is crucial for mitigating cellular damage and maintaining hepatocyte homeostasis. Targeting mitophagy may restore mitochondrial function, alleviate lipotoxic stress, and delay transplant in metabolic liver diseases.</p>","PeriodicalId":50467,"journal":{"name":"Experimental and Clinical Transplantation","volume":"23 12","pages":"824-829"},"PeriodicalIF":0.7,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146042004","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Step Toward Bridging the Gender Gap in Deceased Donor Kidney Transplant.","authors":"Khushboo Saxena, Vivek B Kute, Himanshu V Patel, Divyesh Engineer, Subho Banerjee, Hardik Modi, Jamal Rizvi, Pranjal Modi","doi":"10.6002/ect.2025.0110","DOIUrl":"10.6002/ect.2025.0110","url":null,"abstract":"<p><strong>Objectives: </strong>Gender disparity in access to kidney transplant is a well-established universal challenge. Prior to 2020, duration on the transplant wait list was the only criterium for deceased donor kidney transplant allocation in the state of Gujarat. In January 2020, the State Organ and Tissue Transplant Organization Gujarat was formed, which implemented a point system for deceased donor kidney transplant allocation policy based on human leukocyte antigen mismatch, panel reactive antibody, and donor-specific antibody, among other factors. In this system, adult female recipients are assigned 2 additional points. We investigated the effect of change in deceased donor kidney transplant allocation policy on disparities between male and female recipients.</p><p><strong>Materials and methods: </strong>This is a retrospective, single-center, observational study. The number of male and female recipients who received deceased donor kidney transplant was collected from the medical records at the nephrology department for the period January 2014 through December 2024. We analyzed trends using logistic regression with inverse variance weighting.</p><p><strong>Results: </strong>Over the study period, 3814 kidney transplants were conducted, comprising 2732 from living donors and 1083 from deceased donors. We found a progressive increase in the percentage of women who were deceased donor kidney transplant recipients, from 27.57% in 2019 to 50.76% in 2024 (P < .001). This increase may be attributed to the compounding effect of point allocation to the categories of donor-specific antibody, panel reactive antibody, patient age, and gender.</p><p><strong>Conclusions: </strong>Our study provided new insights for resolution of gaps in deceased donor kidney transplantation between male and female recipients. Implementation of a point-based system for deceased donor kidney transplant allocation policy with extra points for recipients who are women may increase the number of kidney transplants for these recipients. A similar policy may be undertaken by other centers to achieve a temporary solution until underlying factors leading to gender disparity are better understood and methods to overcome these challenges are formed.</p>","PeriodicalId":50467,"journal":{"name":"Experimental and Clinical Transplantation","volume":"23 12","pages":"772-777"},"PeriodicalIF":0.7,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146041945","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of Anterior and Posterior Segment Findings After Cataract Surgery in Patients with a History of Renal Transplantation.","authors":"Ümit Ekşioğlu, Sena Karabay Kılıçarslan, Gülşah Gökgöz, Meriç Yavuz Çolak, Mehmet Haberal","doi":"10.6002/ect.2024.0094","DOIUrl":"https://doi.org/10.6002/ect.2024.0094","url":null,"abstract":"<p><strong>Objectives: </strong>We aimed to investigate the findings of anterior and posterior segments among patients with end-stage renal disease who underwent cataract surgery after renal transplant.</p><p><strong>Materials and methods: </strong>In this cross-sectional study, we included patients who underwent cataract surgery after renal transplant in our hospital between December 2017 and March 2023. We collected ocular biometric measurements, including axial length, white-to-white distance, anterior chamber depth, corneal keratometry, degree of astigmatism, and lens thickness. We also reviewed retinal thickness measure-ments (measured with optic coherence tomography), which we compared versus measurements from healthy controls.</p><p><strong>Results: </strong>We included findings of 48 eyes from patients who underwent cataract surgery after renal transplant and findings of 48 eyes from the control group. Corneal keratometry (P < .001, P < .001) and lens thickness (P = .002) were significantly higher in the transplant group versus the control group, but axial length (P < .001) and white-to-white distance (P = .021) were significantly higher in the control group. Notably, we found a significant difference in retinal thickness in all preoperative parafoveal quadrants (P = .002,P = .011, P < .001, P = .002) and inferior and temporal perifoveal quadrants (P = .012, P = .059). Postoperatively, foveal thickness average and all parafoveal quadrants remained significantly different (P < .001), along with superior and nasal perifoveal quadrant measurements (P = .045, P = .004).</p><p><strong>Conclusions: </strong>Anterior and posterior segment para-meters were significantly different between renal transplant recipients and healthy individuals, possibly because of the effects of renal transplant on ocular microcirculation and metabolism. These insights could guide the selection of intraocular lens power in cataract surgery for transplant patients. However, further research with larger sample sizes is needed to fully grasp the long-term implications of these changes. Exploration of potential links with specific immunosuppressive medications would offer valuable insights.</p>","PeriodicalId":50467,"journal":{"name":"Experimental and Clinical Transplantation","volume":"23 12","pages":"796-801"},"PeriodicalIF":0.7,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146042028","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Role of Artificial Intelligence in Improving the Process of Organ Procurement From Detection to Donation.","authors":"Milad Fendereski Jaz, Sara Shaebani, Fariba Ghorbani","doi":"10.6002/ect.2025.0216","DOIUrl":"10.6002/ect.2025.0216","url":null,"abstract":"<p><p>Organ procurement from patients after brain death faces 2 main challenges: identification of possible donors and interaction with the brain dead donor's family. During this period, the family sees their loved one in a coma-like condition, supported by advanced devices in the intensive care unit and still hoping for recovery, while the life of their loved one has been completely destroyed and only short-term organic survival continues with these devices. After accepting this difficult reality, the family must make a serious decision to donate the patient's organs to unknown patients on wait lists. At this stage, the analytical and conversational capabilities of artificial intelligence can be used as an auxiliary tool alongside organ procurement teams to provide innovative solutions in management of interviews. In our organ procurement unit, we use artificial intelligence as an analytical consultant in case of family refusal. Thus, it is necessary to design and train AI tools based on specialized prompts and based on different consent models (opt-in or opt-out models), as well as that use language in accordance with the laws and cultural requirements of each region. If 2-way interactions continue with such tools, along with recording practical experiences and providing ongoing feedback from organ procurement teams, this technology can continuously learn and improve.</p>","PeriodicalId":50467,"journal":{"name":"Experimental and Clinical Transplantation","volume":"23 12","pages":"845-846"},"PeriodicalIF":0.7,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146042066","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Anatomic-Functional Frame for Middle Hepatic Vein Management in Right/Left Graft Living Donor Liver Transplantation: Venous Mapping in Healthy Human Livers.","authors":"Arnold Radtke, George Sgourakis, Ernesto P Molmenti, Markus Quante, Massimo Malagó, Christoph Steidle","doi":"10.6002/ect.2025.0253","DOIUrl":"https://doi.org/10.6002/ect.2025.0253","url":null,"abstract":"<p><strong>Objectives: </strong>Variability in right and left hemiliver drainage volumes of the middle hepatic vein is of special relevance in living donor liver partitioning. Here, we present a comprehensive classification of middle hepatic vein drainage encompassing func-tional and anatomic components with special reference to middle hepatic vein management in adult living donor liver transplantation.</p><p><strong>Materials and methods: </strong>We evaluated 153 living donor livers among 100 cases of living donor liver transplantation. With 3-dimensional virtual venous reconstructions and maps, we addressed (1) hepatic venous dominance in the total liver, (2) middle hepatic vein/hemiliver-territorial belonging, (3) middle hepa-tic vein drainage contribution to right and left hemilivers based on middle hepatic vein/hemiliver-congestive volume index, and (4) middle hepatic vein anatomic branching patterns.</p><p><strong>Results: </strong>With an established clinical threshold of 30% to 40% middle hepatic vein-congestive volume index for graft selection, a strong correlation between venous dominance, hemiliver belonging, and congestive volume index in overlap with anatomic branching classification was demonstrated. Functional middle hepatic vein variants b and c in overlap with middle hepatic vein branching types A and C implicated middle hepatic vein reconstruction/inclusion in right/left hemiliver grafts. Functional middle hepatic vein variant a (analog to middle hepatic vein branching type B) exhibited safe small congestive drainage volumes in both hemilivers.</p><p><strong>Conclusions: </strong>The proposed middle hepatic vein classification addressed a triple correlation between hepatic vein (total liver volume) dominance and middle hepatic vein (hemiliver volume) belonging related to the middle hepatic vein-congestive volume index in right and left hemiliver as follows: (1) categorize functional middle hepatic vein variants based on congestion risk, (2) identify the left hepatic vein/left hemiliver non-congestive volume index as an additional key parameter in right graft selection, and (3) represent a predictive guide for middle hepatic vein management in right/left graft living donor liver transplantation.</p>","PeriodicalId":50467,"journal":{"name":"Experimental and Clinical Transplantation","volume":"23 12","pages":"811-823"},"PeriodicalIF":0.7,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146041982","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}