Weina Zhang, Jingnan Xu, Yuxiang Wan, Ming Yang, Jinchang Huang
{"title":"Moxibustion combined with guasha therapy for recurrent neutropenia following multiple cycles of chemotherapy of ovarian cancer: A case report","authors":"Weina Zhang, Jingnan Xu, Yuxiang Wan, Ming Yang, Jinchang Huang","doi":"10.1016/j.explore.2024.103031","DOIUrl":"10.1016/j.explore.2024.103031","url":null,"abstract":"<div><p>Neutropenia, a common side effect of chemotherapy for ovarian cancer, was observed in a 47-year-old female patient undergoing a six-cycle chemotherapy regimen. She experienced recurrent neutropenia and leukopenia but refused granulocyte colony-stimulating factor (G-CSF) due to severe bone pain and high costs. Moxibustion combined with guasha therapy (MGT) was administered each time neutropenia occurred. The treatment involved guasha therapy on the bladder meridian (BL) and the governor vessel (GV), followed by moxibustion at Zhongwan (CV 12), Guanyuan (CV 4), and Shenzhu (GV 12) points over 2–3 days. This approach led to the recovery of neutrophil and leukocyte counts, enabling the patient to complete six chemotherapy cycles without G-CSF. These findings suggest that MGT may enhance neutrophil and leukocyte counts in patients with chemotherapy-induced myelosuppression, presenting a potential alternative for those intolerant to G-CSF. However, further high-quality research is needed to confirm its efficacy.</p></div>","PeriodicalId":50459,"journal":{"name":"Explore-The Journal of Science and Healing","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2024-07-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141581396","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"What happens when politicians not physicians make the medical decisions?","authors":"Stephan A. Schwartz","doi":"10.1016/j.explore.2024.103025","DOIUrl":"10.1016/j.explore.2024.103025","url":null,"abstract":"","PeriodicalId":50459,"journal":{"name":"Explore-The Journal of Science and Healing","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2024-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1550830724001320/pdfft?md5=e1320f310625f7912902c521a69d0aa4&pid=1-s2.0-S1550830724001320-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141706398","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Getrude Mphwanthe , Yehuda Tri Nugroho Supranoto , L. Susan Wieland
{"title":"Low glycemic index or low glycemic load diets for people with overweight or obesity: Summary of a Cochrane review","authors":"Getrude Mphwanthe , Yehuda Tri Nugroho Supranoto , L. Susan Wieland","doi":"10.1016/j.explore.2024.103024","DOIUrl":"10.1016/j.explore.2024.103024","url":null,"abstract":"","PeriodicalId":50459,"journal":{"name":"Explore-The Journal of Science and Healing","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2024-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141639197","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Psychobiotics in depression: A review","authors":"Angie Lillehei","doi":"10.1016/j.explore.2024.103023","DOIUrl":"10.1016/j.explore.2024.103023","url":null,"abstract":"","PeriodicalId":50459,"journal":{"name":"Explore-The Journal of Science and Healing","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2024-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141695874","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The effects of connective tissue massage and classical massage on pain, lumbar mobility, function, disability, and well-being in chronic low back pain: A three-arm randomized controlled trial","authors":"Cansu Dal , Meltem Koç , Banu Bayar","doi":"10.1016/j.explore.2024.103029","DOIUrl":"10.1016/j.explore.2024.103029","url":null,"abstract":"<div><h3>Background</h3><p>Chronic low back pain (CLBP) is a common musculoskeletal disorder. Effect of massage in the management of CLBP has been documented, but it is not clear which massage regimen is more effective. This study was carried out to compare the effect of connective tissue massage and classical massage on pain, lumbar mobility, function, disability, and well-being among patients with CLBP.</p></div><div><h3>Methods</h3><p>The study included 30 participants who were randomly assigned to one of three intervention groups: the connective tissue massage group (CTMG; <em>n</em> = 10), the classical massage group (CMG; <em>n</em> = 10), and a standard physiotherapy/control group (CG; <em>n</em> = 10). The interventions were administered three times a week for four consecutive weeks. Assessments were conducted at baseline and at the end of the fourth week. Pain severity (Visual Analog Scale), lumbar mobility (Modified Schober Test), function (Back Pain Functional Scale), disability (Roland Morris Disability Questionnaire), and well-being (Short Form-36/SF-36) was evaluated.</p></div><div><h3>Results</h3><p>All groups exhibited improvements in pain, lumbar mobility, function, and disability after 4 weeks (<em>p</em> < 0.05). The CMG showed enhancements in physical function, bodily pain, role physical, and role emotional subgroups of SF-36. The CTMG demonstrated improvements in all subgroups of SF-36 except general health (<em>p</em> < 0.05), while the CG only improved in the physical function subgroup (<em>p</em> < 0.05). A 2-way repeated measures ANOVA revealed a significant group-time interaction for MST (<em>p</em> = 0.04), Bodily Pain (<em>p</em> = 0.025) and Role Physical (<em>p</em> = 0.015).</p></div><div><h3>Conclusions</h3><p>The findings obtained from this study showed that CTMG was superior to CMG and CG in increasing lumbar mobility, and both massage applications were superior to the CG in increasing the well-being.</p></div>","PeriodicalId":50459,"journal":{"name":"Explore-The Journal of Science and Healing","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2024-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141564999","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Prognostication: A fading Hippocratic art?","authors":"Thomas John Papadimos","doi":"10.1016/j.explore.2024.103026","DOIUrl":"10.1016/j.explore.2024.103026","url":null,"abstract":"<div><p>Over the past 75 years modern medicine has advanced in its ability to diagnose and treat many diseases. However, the medical profession's ability to prognosticate the course and outcome of an illness has not satisfied the needs of many patients. Physicians must not lose the ability, or desire, to consider the <em>whole person</em> in relation to a patient's disease. We need to ask ourselves what person has the disease, not what disease the person has. Here I endeavor to demonstrate why Hippocrates valued prognostication highly, how its importance may have faded from the consciousness of current medical practice, and how modern technology is attempting to reinvent or revise it.</p></div>","PeriodicalId":50459,"journal":{"name":"Explore-The Journal of Science and Healing","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2024-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1550830724001332/pdfft?md5=b3bba08d044fbaeb7a7c02e3b49947d8&pid=1-s2.0-S1550830724001332-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141604472","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The effect of neurolinguistic programming and progressive muscle relaxation exercises on breastfeeding success and breastfeeding self-efficacy: A randomized controlled trial","authors":"Ayşegül Kiliçli , Sidar Gül","doi":"10.1016/j.explore.2024.103027","DOIUrl":"https://doi.org/10.1016/j.explore.2024.103027","url":null,"abstract":"<div><h3>Introduction</h3><p>This research was to determine the effect of neurolinguistic programming (NLP) and progressive muscle relaxation exercises (PMRE) on breastfeeding success and breastfeeding self-efficacy in primiparous women after cesarean section.</p></div><div><h3>Material and methods</h3><p>This is a single-blind, three-arm, parallel-group, randomized controlled trial. Data were collected between 01 October 2023, and 18 December 2023. The sample of the study consisted of 99 primiparous women who gave birth by cesarean section (NLP=33, PMRE=33, and control=33). Women were randomly assigned to the groups. Starting from the first mobilization time after cesarean section, NLP was applied to the NLP group and PMRE was applied to the PMRE group every eight hours for 48 h. In the control group, NLP or PMRE was not applied and the women were allowed to rest on their backs. The primary outcomes of the study were breastfeeding success and breastfeeding self-efficacy.</p></div><div><h3>Results</h3><p>The mean scores of breastfeeding success and breastfeeding self-efficacy measured over time were highest in the NLP group and lowest in the control group (<em>p</em><.05). The mean scores of breastfeeding success and breastfeeding self-efficacy measured over time increased by 78.4 %, and 97.7 %, respectively, in the NLP group compared to the control group, 74.7 %, and 88.1 %, in the PMRE group compared to the control group, and 13.5 %, and 90.2 %, respectively, in the NLP group compared to the PMRE group (<em>p<.05</em>).</p></div><div><h3>Conclusion</h3><p>NLP intervention may have a more positive effect on breastfeeding success and breastfeeding self-efficacy than PMRE intervention.</p></div><div><h3>Trial and protocol registration</h3><p>ClinicalTrials.gov, NCT06070792.</p></div>","PeriodicalId":50459,"journal":{"name":"Explore-The Journal of Science and Healing","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2024-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141606277","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A McLachlan, T Kingi, W Waitoki, RW Wirihana, A Hoeta, S Kinred, P Pehi, P Harris, H. Jones
{"title":"The TOHU framework: Sensing and interpreting tohu to heal from trauma","authors":"A McLachlan, T Kingi, W Waitoki, RW Wirihana, A Hoeta, S Kinred, P Pehi, P Harris, H. Jones","doi":"10.1016/j.explore.2024.103017","DOIUrl":"10.1016/j.explore.2024.103017","url":null,"abstract":"<div><p>This hypotheses article presents understandings and practices of tohu (signs) in the personal, eco-environmental, and spiritual wellbeing of Māori. Tohu can be observed in the natural, social, physical, or spiritual environment, and within a Māori worldview provide important ways of understanding and responding to phenomena. Wānanga (shared dialogue and debate) were held with seven Māori clinical psychologists from He Paiaka Tōtara (Māori Psychologist Network) and two mātauranga Māori specialists to explore their experiences, knowledge, and perspectives about tohu, with their insights collected through online information sharing. Our wānanga goals were to inform the creation of a therapeutic framework to address patu ngākau, psychological and spiritual trauma experienced by Māori. The results identified that tohu are located within the person and their environment, and the importance of exploring how tohu are interpreted. We propose a TOHU acronym as a framework for understanding and addressing the multifaceted impacts of patu ngākau.</p></div>","PeriodicalId":50459,"journal":{"name":"Explore-The Journal of Science and Healing","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2024-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141581397","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Incorporating biofeedback into the Mindfulness in Motion Intervention for health care professionals: Impact on sleep and stress","authors":"Justin J Merrigan , Maryanna Klatt , Catherine Quatman-Yates , Angela Emerson , Jamie Kronenberg , Morgan Orr , Jacqueline Caputo , Kayla Daniel , Riley Summers , Yulia Mulugeta , Beth Steinberg , Joshua A. Hagen","doi":"10.1016/j.explore.2024.103022","DOIUrl":"10.1016/j.explore.2024.103022","url":null,"abstract":"<div><h3>Context</h3><p>Health care providers (HCP) experience high stress and burnout rates. Mindfulness Based Interventions (MBI) with biofeedback may help improve resiliency but require further research.</p></div><div><h3>Design and Study Participants</h3><p>Aims were to evaluate changes in sleep patterns, nocturnal physiology, stress, mood disturbances, and perceived experience with biofeedback during the Mindfulness in Motion (MIM) intervention. Data from 66 HCP were included after removing those below 75 % compliance with wearable sensors and wellness surveys. Participants were enrolled in MIM, including eight weekly one-hour virtually delivered synchronous group meetings and ∼10 min of mindfulness home practice at least 3 times per week using a mobile application. Participants wore wearable sensors to monitor sleep and nocturnal physiology and completed short daily stress and mood disturbances.</p></div><div><h3>Results</h3><p>According to mixed effect models, no sleep nor physiological metrics changed across MIM (<em>p</em> > 0.05). More time was spent in bed after MIM sessions (8.33±1.03 h) compared to night before (8.05±0.93 h; <em>p</em> = 0.040). Heart rate variability was lower nights after MIM (33.00±15.59 ms) compared to nights before (34.50±17.04 ms; <em>p</em> = 0.004) but was not clinically meaningful (effect= 0.033). Significant reductions were noted in perceived stress at weeks 3 through 8 compared to Baseline and lower Total Mood Disturbance at weeks 3, 5, 6, and 8 compared to Baseline (<em>p</em> < 0.001).</p></div><div><h3>Conclusions</h3><p>Participating in the MIM with mobile applications and wearable sensors reduced perceived stress and mood disturbances but did not induce physiological changes. Additional research is warranted to further evaluate objective physiological outcomes while controlling for confounding variables (e.g., alcohol, medications).</p></div>","PeriodicalId":50459,"journal":{"name":"Explore-The Journal of Science and Healing","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2024-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1550830724001290/pdfft?md5=62d0c13531a0a74d74bc2b8b6957742c&pid=1-s2.0-S1550830724001290-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141564998","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jie Gao , Bin Chen , Weipeng Ji , Shuo Tao , Zi Ye , Xudong Wang
{"title":"Auricular point acupressure for managing postoperative pain and reducing anxiety in patients with perianal abscesses","authors":"Jie Gao , Bin Chen , Weipeng Ji , Shuo Tao , Zi Ye , Xudong Wang","doi":"10.1016/j.explore.2024.103020","DOIUrl":"10.1016/j.explore.2024.103020","url":null,"abstract":"<div><h3>Objective</h3><p>The objective of this study is to assess the efficacy of auricular point acupressure in relieving postoperative pain and reducing anxiety among patients with perianal abscesses.</p></div><div><h3>Methods</h3><p>We included 61 patients with perianal abscesses who were admitted to the Nantong First People's Hospital between July 2019 and June 2020 and were scheduled to undergo one-stage radical surgery. We divided them into the treatment group (<em>n</em> = 31), where patients were administered preoperative auricular acupressure targeting the bilateral <em>Shenmen</em>, subcortical, and other points. They were instructed to apply pressure five to six times per day, each time for about 3–5 min. Patients in the control group (<em>n</em> = 30) received routine preoperative preparation. The treatment duration for both groups was one week. We compared the two groups using the pain visual analog scale (VAS) scores, the use of additional postoperative analgesics, and scores on the Hamilton anxiety and depression scales pre- and post-surgery at 6 h, 24 h, 48 h, 72 h, and 1 week after surgery, as well as at the time of the first bowel movement.</p></div><div><h3>Results</h3><p>Patients in the treatment group reported lower VAS scores than those of the control group at 48 h, 72 h, 1 week, and at the first defecation post-surgery, and the differences were statistically significant (all <em>P</em> < 0.05). Additional postoperative analgesics were used in seven patients in the treatment group (22.58 %) and in 10 patients in the control group (33.33 %). The difference between the two groups was not statistically significant (<em>χ</em><sup>2</sup> = 0.88, <em>P</em> = 0.35). Postoperative scores for the Hamilton Anxiety Rating Scale (HAM-A) and the Hamilton Depression Rating Scale (HAM-D) in the treatment group were significantly lower than those in the control group (<em>P</em> < 0.05).</p></div><div><h3>Conclusion</h3><p>The results of this study demonstrated that auricular point acupressure was effective in alleviating postoperative pain in patients with perianal abscesses and simultaneously reduced their postoperative psychological stress reactions. This dual effect provided both pain relief and a reduction of anxiety with fewer adverse reactions, making it a safe and effective treatment option.</p></div>","PeriodicalId":50459,"journal":{"name":"Explore-The Journal of Science and Healing","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2024-06-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141477874","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}