Explore-The Journal of Science and Healing最新文献

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The human dimension: integrating whole health into a community-engaged medical education curriculum 人的维度:将整体健康纳入社区参与的医学教育课程。
IF 2.2 4区 医学
Explore-The Journal of Science and Healing Pub Date : 2026-01-01 Epub Date: 2025-12-03 DOI: 10.1016/j.explore.2025.103302
Lawrence Rosen, Carmela Rocchetti
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引用次数: 0
Reconciling Indigenous knowledges and Western scholarship. Is it possible? 调和本土知识与西方学术。这可能吗?
IF 2.2 4区 医学
Explore-The Journal of Science and Healing Pub Date : 2026-01-01 Epub Date: 2025-11-17 DOI: 10.1016/j.explore.2025.103286
Natasha Tassell-Matamua
{"title":"Reconciling Indigenous knowledges and Western scholarship. Is it possible?","authors":"Natasha Tassell-Matamua","doi":"10.1016/j.explore.2025.103286","DOIUrl":"10.1016/j.explore.2025.103286","url":null,"abstract":"","PeriodicalId":50459,"journal":{"name":"Explore-The Journal of Science and Healing","volume":"22 1","pages":"Article 103286"},"PeriodicalIF":2.2,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145571890","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effects of traditional Chinese medicine decoctions on coagulation and deep vein thrombosis after total hip arthroplasty: Network meta-analysis 中药煎剂对全髋关节置换术后凝血及深静脉血栓形成的影响:网络荟萃分析
IF 2.2 4区 医学
Explore-The Journal of Science and Healing Pub Date : 2026-01-01 Epub Date: 2025-11-07 DOI: 10.1016/j.explore.2025.103278
Hang Shi , Yichen Zhao , Xiaoyu Shi , Yimin Hao , Dongxu Ren , Yitong Liu , Gang Zhao
{"title":"Effects of traditional Chinese medicine decoctions on coagulation and deep vein thrombosis after total hip arthroplasty: Network meta-analysis","authors":"Hang Shi ,&nbsp;Yichen Zhao ,&nbsp;Xiaoyu Shi ,&nbsp;Yimin Hao ,&nbsp;Dongxu Ren ,&nbsp;Yitong Liu ,&nbsp;Gang Zhao","doi":"10.1016/j.explore.2025.103278","DOIUrl":"10.1016/j.explore.2025.103278","url":null,"abstract":"<div><h3>Background</h3><div>Deep vein thrombosis (DVT) is a common and severe complication following total hip arthroplasty (THA). It significantly impacts patient recovery and quality of life. In recent years, certain traditional Chinese medicine (TCM) decoctions have shown potential in the prevention and treatment of DVT. However, a systematic evaluation of their efficacy and safety remains limited. This study aims to comprehensively assess the clinical effects and safety profile of TCM decoctions in managing DVT after THA via a network meta-analysis (NMA).</div></div><div><h3>Methods</h3><div>The China Biomedical Literature Database (CBM), China National Knowledge Infrastructure (CNKI), Wanfang Data, VIP Database, PubMed, Embase, Cochrane Library, and Web of Science were searched to identify randomized controlled trials (RCTs) evaluating the efficacy of TCM decoctions for treating post-THA DVT from 2020 to July 17, 2024. The Cochrane risk-of-bias tool was employed to assess the methodological quality of the included studies. Data were analyzed through NMA with Stata 17 and R 4.3.2. A Bayesian random-effects model was employed for the analysis, and the surface under the cumulative ranking curve (SUCRA) values for each intervention were calculated across different outcome measures. Publication bias was assessed through funnel plots.</div></div><div><h3>Results</h3><div>64 studies involving 5,603 patients were included. The results demonstrated that Huoxue Tongmai Decoction (SUCRA = 74.95%, RR = 0.178, 95% credible interval (95% CrI) = 0.043, 0.521) was the most effective intervention for reducing DVT incidence rate (IR). Huoxue Xiaoshuan Decoction (SUCRA = 94.18%, weighted mean difference (WMD) = -6.42, 95% CrI: -13.7 to 0.941) was the most effective in lowering activated partial thromboplastin time (APTT), while Tongmai Decoction (SUCRA = 98.84%, WMD = -2.74, 95% CrI: -4.71 to -0.733) showed the greatest efficacy in lowering <span>d</span>-dimer (D-D) levels. Qingyu Decoction (SUCRA = 85.34%, WMD = -1.41, 95% CrI: -2.49 to -0.330) was the most effective intervention for fibrinogen (FIB) reduction. Huoxue Xiaoshuan Decoction (SUCRA = 80.53%, WMD = -1.93, 95% CrI: -7.32 to 3.49) was the most effective in prolonging prothrombin time (PT). Additionally, Huoxue Shujin Decoction (SUCRA = 76.38%, WMD = -2.49, 95% CrI: -14.0 to 9.07) demonstrated the highest efficacy in prolonging thrombin time (TT). In terms of DVT IR, <span>d</span>-D, and FIB, TCM decoctions exhibited superior efficacy in comparison to conventional treatment.</div></div><div><h3>Conclusion</h3><div>This study presents evidence that TCM decoctions can improve coagulation parameters to varying degrees and significantly reduce the incidence of DVT following THA. Among the interventions analyzed, Huoxue Tongmai Decoction exhibited the most pronounced effect in reducing DVT incidence.</div></div>","PeriodicalId":50459,"journal":{"name":"Explore-The Journal of Science and Healing","volume":"22 1","pages":"Article 103278"},"PeriodicalIF":2.2,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145493022","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Apparent regeneration of Osteolytic bone metastases and resolution of pulmonary metastases associated with traditional Chinese medicine treatment in a patient with thyroid cancer: A hypothesis-generating case report 甲状腺癌患者溶骨性骨转移瘤的明显再生和肺转移瘤的消退与中医治疗相关:一个产生假设的病例报告。
IF 2.2 4区 医学
Explore-The Journal of Science and Healing Pub Date : 2026-01-01 Epub Date: 2025-12-21 DOI: 10.1016/j.explore.2025.103309
Minghua Wei , Feng Liu , Yongjian Liu , Jifeng Dang , Qingxuan Cao , Zhou Wang
{"title":"Apparent regeneration of Osteolytic bone metastases and resolution of pulmonary metastases associated with traditional Chinese medicine treatment in a patient with thyroid cancer: A hypothesis-generating case report","authors":"Minghua Wei ,&nbsp;Feng Liu ,&nbsp;Yongjian Liu ,&nbsp;Jifeng Dang ,&nbsp;Qingxuan Cao ,&nbsp;Zhou Wang","doi":"10.1016/j.explore.2025.103309","DOIUrl":"10.1016/j.explore.2025.103309","url":null,"abstract":"<div><h3>Introduction</h3><div>Osteolytic bone metastases are a severe complication of advanced thyroid cancer, associated with a poor prognosis. Complete structural regeneration of affected bone is exceedingly rare within conventional therapeutic paradigms. The pathology involves a “vicious cycle” of bone destruction, largely mediated by dysregulation of the RANK/RANKL/OPG signaling axis. This report documents an exceptional clinical observation: the apparent complete regeneration of extensive osteolytic bone metastases and simultaneous regression of pulmonary metastases, observed in a patient undergoing traditional Chinese medicine (TCM) monotherapy after declining conventional treatments. This case highlights the potential for TCM to offer avenues for future investigation in integrative oncology.</div></div>","PeriodicalId":50459,"journal":{"name":"Explore-The Journal of Science and Healing","volume":"22 1","pages":"Article 103309"},"PeriodicalIF":2.2,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145866316","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Reflection on the use of sensory ethnography and creative methods 对感官人种学和创造性方法运用的反思
IF 2.2 4区 医学
Explore-The Journal of Science and Healing Pub Date : 2026-01-01 Epub Date: 2025-12-03 DOI: 10.1016/j.explore.2025.103301
Muhammad Taufan Umasugi
{"title":"Reflection on the use of sensory ethnography and creative methods","authors":"Muhammad Taufan Umasugi","doi":"10.1016/j.explore.2025.103301","DOIUrl":"10.1016/j.explore.2025.103301","url":null,"abstract":"","PeriodicalId":50459,"journal":{"name":"Explore-The Journal of Science and Healing","volume":"22 1","pages":"Article 103301"},"PeriodicalIF":2.2,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145732870","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sacred suffering and stigma: Cultural pathways to mental health in Ethiopia 神圣的痛苦和耻辱:埃塞俄比亚通往精神健康的文化途径。
IF 2.2 4区 医学
Explore-The Journal of Science and Healing Pub Date : 2026-01-01 Epub Date: 2025-11-13 DOI: 10.1016/j.explore.2025.103289
Girum Melkamu Tadesse
{"title":"Sacred suffering and stigma: Cultural pathways to mental health in Ethiopia","authors":"Girum Melkamu Tadesse","doi":"10.1016/j.explore.2025.103289","DOIUrl":"10.1016/j.explore.2025.103289","url":null,"abstract":"<div><div>Mental health in Ethiopia is still highly misunderstood and culturally embedded issue that is often unpacked at the spiritual level and addressed outside the formal healthcare regimes. This qualitative study examines how people with mental health conditions, their families and community members conceive mental illness in a world of religious worldviews, poverty and stigma. Interview and group discussions were carried out within urban and rural community contexts to explore local perspectives and lived experiences. Participants tended to consider the mental distress as a non-medical issue, a spiritual or a moral disruption that was often associated with phenomena, such as spirit intrusion, curses or divine punishment. Such beliefs influenced care-seeking behavior in a great way as patients resorted to Orthodox Christian healing rituals, holy water practices, and native spiritual mediators prior to the idea of seeking clinical services. The economic hardship, distance to facilities and perception of public health facilities as unwelcoming/insufficient further limited the access to biomedical care. Stigma arose as a frequent theme that expressed itself in labeling, marginalizing, and hiding the condition of affected persons – especially women, who are subject to further criticism based on the social norms of morality and family roles. In spite of these setbacks, meaningful psychosocial support and inclusive practices were observed in some community actors such as the faith-based organizations and local initiatives. There was also a hybrid model of healing in the cities wherein some of the participants engaged in both spiritual and psychiatric interventions while moving back and forth between the two to create culturally palatable routes to recovery. The findings highlight the pitfalls of bringing in canned mental health models without regard to local knowledge systems and social reality. Any mental health plan in Ethiopia has to be multi-dimensional, accepting the traditional beliefs, addressing the gendered and economic disparity, and partnering with the religious institutions. This research highlights the importance of designing community-based, culturally resonant interventions that reflect Ethiopia’s unique moral landscapes and collective values.</div></div>","PeriodicalId":50459,"journal":{"name":"Explore-The Journal of Science and Healing","volume":"22 1","pages":"Article 103289"},"PeriodicalIF":2.2,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145566123","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Body intelligence and nature: A convergence of Persian medicine and modern biophysics 身体智能与自然:波斯医学与现代生物物理学的融合
IF 2.2 4区 医学
Explore-The Journal of Science and Healing Pub Date : 2026-01-01 Epub Date: 2025-12-18 DOI: 10.1016/j.explore.2025.103308
Babak Daneshfard , Majid Nimrouzi , Foad Masihpour , Mohsen Manouchehri , Mahboubeh Sadat Fateminasab , Alireza Asghari
{"title":"Body intelligence and nature: A convergence of Persian medicine and modern biophysics","authors":"Babak Daneshfard ,&nbsp;Majid Nimrouzi ,&nbsp;Foad Masihpour ,&nbsp;Mohsen Manouchehri ,&nbsp;Mahboubeh Sadat Fateminasab ,&nbsp;Alireza Asghari","doi":"10.1016/j.explore.2025.103308","DOIUrl":"10.1016/j.explore.2025.103308","url":null,"abstract":"<div><div>Physical intelligence refers to the capacity of living systems to sense, interpret, and respond adaptively to internal and external signals through integrated biochemical, bioelectrical, and biophysical processes. This conceptual review examines points of convergence between contemporary biophysical research, including biofield science, biophotonics, and systems neuroscience, and classical Persian Medicine (PM), particularly the framework of <em>Tabiʿat-e Modabbereh</em> (the intelligent, governing nature), <em>Arwah</em> (spirits), <em>Quwa</em> (faculties), and <em>Af’al</em> (actions). Rather than equating traditional constructs with scientific entities, this paper identifies analogical parallels that may support new hypotheses on whole-system regulation. A critical appraisal of emerging evidence regarding energetic dysregulation and early disease patterns is included. The review concludes with specific, testable research questions aimed at advancing integrative biophysical–Persian Medicine models.</div></div>","PeriodicalId":50459,"journal":{"name":"Explore-The Journal of Science and Healing","volume":"22 1","pages":"Article 103308"},"PeriodicalIF":2.2,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145839805","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The five anxieties tearing America apart 撕裂美国的五大焦虑
IF 2.2 4区 医学
Explore-The Journal of Science and Healing Pub Date : 2026-01-01 Epub Date: 2025-11-19 DOI: 10.1016/j.explore.2025.103284
Stephan A. Schwartz
{"title":"The five anxieties tearing America apart","authors":"Stephan A. Schwartz","doi":"10.1016/j.explore.2025.103284","DOIUrl":"10.1016/j.explore.2025.103284","url":null,"abstract":"","PeriodicalId":50459,"journal":{"name":"Explore-The Journal of Science and Healing","volume":"22 1","pages":"Article 103284"},"PeriodicalIF":2.2,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145839804","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Music therapy for autistic people: summary of a Cochrane review 自闭症患者的音乐治疗:Cochrane综述摘要。
IF 2.2 4区 医学
Explore-The Journal of Science and Healing Pub Date : 2026-01-01 Epub Date: 2025-11-19 DOI: 10.1016/j.explore.2025.103288
Yasmine Ahmed Mourad Asaad , Shahd Ashraf Izzeldin Abdalla , Ana Beatriz Pizarro
{"title":"Music therapy for autistic people: summary of a Cochrane review","authors":"Yasmine Ahmed Mourad Asaad ,&nbsp;Shahd Ashraf Izzeldin Abdalla ,&nbsp;Ana Beatriz Pizarro","doi":"10.1016/j.explore.2025.103288","DOIUrl":"10.1016/j.explore.2025.103288","url":null,"abstract":"","PeriodicalId":50459,"journal":{"name":"Explore-The Journal of Science and Healing","volume":"22 1","pages":"Article 103288"},"PeriodicalIF":2.2,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145764400","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A reply to “Reflection on the use of sensory ethnography and creative methods” 对“运用感官人种学和创造性方法的思考”的答复
IF 2.2 4区 医学
Explore-The Journal of Science and Healing Pub Date : 2026-01-01 Epub Date: 2025-12-17 DOI: 10.1016/j.explore.2025.103307
Donna M Thomas , Elaine Rycroft , Kirsty Allan , Saima Sharif
{"title":"A reply to “Reflection on the use of sensory ethnography and creative methods”","authors":"Donna M Thomas ,&nbsp;Elaine Rycroft ,&nbsp;Kirsty Allan ,&nbsp;Saima Sharif","doi":"10.1016/j.explore.2025.103307","DOIUrl":"10.1016/j.explore.2025.103307","url":null,"abstract":"","PeriodicalId":50459,"journal":{"name":"Explore-The Journal of Science and Healing","volume":"22 1","pages":"Article 103307"},"PeriodicalIF":2.2,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145789829","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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