{"title":"A link between physical and mental health: Brain pathways","authors":"Angie Lillehei","doi":"10.1016/j.explore.2024.103103","DOIUrl":"10.1016/j.explore.2024.103103","url":null,"abstract":"","PeriodicalId":50459,"journal":{"name":"Explore-The Journal of Science and Healing","volume":"21 1","pages":"Article 103103"},"PeriodicalIF":1.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142899276","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Xianzhe Zhang , Xiaoming Du , Jie Xiang , Qifa Shu , Haoyun Huang , Yi Guo , Tao Wang , Yimei Hu , Junzhi He
{"title":"Effective treatment of non-union after internal fixation of femoral neck fracture using integrated traditional Chinese and western medicine","authors":"Xianzhe Zhang , Xiaoming Du , Jie Xiang , Qifa Shu , Haoyun Huang , Yi Guo , Tao Wang , Yimei Hu , Junzhi He","doi":"10.1016/j.explore.2024.103095","DOIUrl":"10.1016/j.explore.2024.103095","url":null,"abstract":"<div><h3>Background</h3><div>Hip fractures, particularly femoral neck and intertrochanteric fractures, represent approximately 6.37 % of all fractures, with incidence rates showing an upward trend annually.</div></div><div><h3>Case Presentation</h3><div>This report presents a case of a 55-year-old female with a femoral neck fracture who underwent internal fixation. One-year post-surgery, the patient continued to experience hip pain, and computed tomography (CT) scans revealed non-union of the fracture. The patient received an integrated treatment approach combining traditional Chinese and Western medicine, involving the alternating administration of osteopeptide tablets and Guijia Jiangu capsules, a proprietary herbal formulation. No additional pharmacological or surgical interventions were employed. Seven months after initiating the treatment, digital radiography (DR) examinations showed that the fracture had largely healed. At the seven-month follow-up, and nearly four years thereafter, the patient reported no discomfort in the hip region. Subsequent DR examinations revealed no signs of avascular necrosis of the femoral head, and no adverse events were noted. The internal fixation device was removed five years post-fracture.</div></div><div><h3>Conclusion</h3><div>The results indicate that integrated traditional Chinese and Western medicine may effectively treat non-union after internal fixation of femoral neck fractures, though further studies are warranted to confirm these outcomes.</div></div>","PeriodicalId":50459,"journal":{"name":"Explore-The Journal of Science and Healing","volume":"21 1","pages":"Article 103095"},"PeriodicalIF":1.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142822897","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Moving cupping therapy combined with acupoint bloodletting for plaque psoriasis: A case report","authors":"Xia Qiao, Chunyan Yang, Wenxin Yang, Yan Li","doi":"10.1016/j.explore.2024.103098","DOIUrl":"10.1016/j.explore.2024.103098","url":null,"abstract":"<div><h3>Introduction</h3><div>Psoriasis is a chronic inflammatory skin disease that can present in various phenotypes, with the most common form being plaque psoriasis. Currently, no type of psoriasis can be cured, and existing treatment options are associated with certain safety concerns. In recent years, traditional Chinese medicine has achieved great results in treating psoriasis. Cupping therapy is a widely used method in China. In this case, the combination of moving cupping therapy and acupoint bloodletting has demonstrated a favorable therapeutic effect on plaque psoriasis.</div></div><div><h3>Case presentation</h3><div>A 35-year-old male diagnosed with plaque psoriasis for 20 years, presented with generalized itchy, erythematous, and scaly skin. The patient underwent moving cupping therapy combined with acupoint bloodletting once every other day, three times per week, for a total duration of 8 weeks. After treatment, the erythema, plaques, and scales on the patient's entire body had mostly resolved. The Psoriasis Area and Severity Index (PASI) score decreased from 50 to 5, the Body Surface Area (BSA) improved from 60 % to 4 %, and the Dermatology Life Quality Index (DLQI) decreased from 17 to 2 points. No relapse was observed during the 6-month follow-up.</div></div><div><h3>Conclusion</h3><div>This case demonstrates that moving cupping therapy combined with acupoint bloodletting is well tolerated and effective in relieving skin lesion symptoms and improving the quality of life in patients with plaque psoriasis. As a cost-effective adjunctive therapy, moving cupping therapy combined with acupoint bloodletting holds promise as a non-pharmacological treatment option for plaque psoriasis.</div></div>","PeriodicalId":50459,"journal":{"name":"Explore-The Journal of Science and Healing","volume":"21 1","pages":"Article 103098"},"PeriodicalIF":1.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142824747","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jiayu Su , Tingwei Quan , Tianrong Liao , Yu Luo , Xin Fan , Mingfu Pan , Hongzhen Tang
{"title":"Effectiveness and safety of acupuncture for melasma: A meta-analysis of randomized controlled trials","authors":"Jiayu Su , Tingwei Quan , Tianrong Liao , Yu Luo , Xin Fan , Mingfu Pan , Hongzhen Tang","doi":"10.1016/j.explore.2024.103108","DOIUrl":"10.1016/j.explore.2024.103108","url":null,"abstract":"<div><h3>Background</h3><div>Treating melasma remains challenging. We conducted a meta-analysis to assess the effectiveness and safety of acupuncture as a treatment option.</div></div><div><h3>Methods</h3><div>We searched three English and four Chinese databases up to January 2, 2024. The primary outcome was the total effective rate, while secondary outcomes included skin lesion area and color scores, total lesion score, and adverse effects. Study quality was assessed using the risk of bias tool, and data were analyzed with Review Manager 5.4. The GRADE approach evaluated evidence certainty.</div></div><div><h3>Results</h3><div>This study included 22 studies with 1644 participants. Findings indicate that acupuncture significantly outperforms Western medicine and other treatments (risk ratio [RR] = 1.21, 95 % confidence interval [CI] (1.18, 1.30), <em>P</em> < 0.00001, I² = 34 %). Acupuncture effectively reduces the area of skin lesions (mean difference [MD] = −0.35, 95 % CI (−0.52, −0.19), <em>P</em> < 0.0001, I² = 93 %), lightens color (MD = −0.45, 95 % CI (−0.58, −0.31), <em>P</em> < 0.00001, I² = 89 %), and lowers the total score of skin lesions (MD = -1.00, 95 % CI (−1.29, −0.70), <em>P</em> < 0.00001, I² = 79 %). Adverse reactions were infrequent with acupuncture. The most common needling sites were in the facial lesion area, noted in 17 studies. Sanyinjiao (SP6) was the most frequently used acupoint (<em>n</em> = 8), followed by Hegu (LI4) (<em>n</em> = 7) and Xuehai (SP10) (<em>n</em> = 7). Other commonly used acupoints included Tianshu (ST25), Zusanli (ST36), Taichong (LR3), and Zhongwan (RN12). All secondary outcomes, except for the primary outcome, were rated as very low quality.</div></div><div><h3>Conclusion</h3><div>This review confirms that acupuncture therapy effectively reduces the area and color of melasma lesions and lowers lesion scores. Acupuncture therapy appears to be a safe and effective treatment option for melasma; however, results should be interpreted cautiously due to potential publication and regional biases.</div></div><div><h3>Registration</h3><div>CRD42024503394.</div></div>","PeriodicalId":50459,"journal":{"name":"Explore-The Journal of Science and Healing","volume":"21 1","pages":"Article 103108"},"PeriodicalIF":1.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142985292","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Chang-Tze Ricky Yu , Dean I. Radin , Chen-Yu Chu , Yung-Jong Shiah
{"title":"Effects of intentionally-treated water on cell migration of human glioblastoma cells","authors":"Chang-Tze Ricky Yu , Dean I. Radin , Chen-Yu Chu , Yung-Jong Shiah","doi":"10.1016/j.explore.2024.103100","DOIUrl":"10.1016/j.explore.2024.103100","url":null,"abstract":"<div><h3>Objective</h3><div>This study investigated if human glioblastoma cancer cells (U87MG cell line) cultured in intentionally treated water could reduce cell migration, a prerequisite for metastasis, as compared to the same cells cultured in untreated (control) water.</div></div><div><h3>Design</h3><div>Three Buddhist monks entered a meditative state and directed their awareness to bottles of ultrapure water while holding the intention that the water would cause beneficial changes in U87MG. The study was conducted double-blind whereby all aspects of the study involving cell growth and migration measures, as well as all subsequent statistical evaluations, were performed without knowledge of the type of water being used. Cell cultures were incubated in growth mediums prepared with treated and untreated water, and a wound healing assay was employed to measure cell migration.</div></div><div><h3>Results</h3><div>U87MG cells incubated with treated water migrated less efficiently than the same cells in untreated water. A repeated measures ANOVA, spanning four time periods (0, 3, 6, and 9 h), determined that the time × water condition interaction was associated with p < 0.005.</div></div><div><h3>Conclusion</h3><div>Intentioned awareness appeared to change as-yet unknown properties of ultrapure water, resulting in a reduction of U87MG cells migration activity. Further research is warranted to replicate these results and to investigate the underlying protein expression mechanisms in influencing cell migration.</div></div>","PeriodicalId":50459,"journal":{"name":"Explore-The Journal of Science and Healing","volume":"21 1","pages":"Article 103100"},"PeriodicalIF":1.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142866105","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kimberlee Flike , Elizabeth Naughton , Rosalie Bouchard-Bihr , Abigail Tague , Gretchen Willwerth , Matthew Nault , Justeen Hyde
{"title":"Using What Matters Most to improve health care delivery for individuals and populations of veterans experiencing homelessness and substance use disorders","authors":"Kimberlee Flike , Elizabeth Naughton , Rosalie Bouchard-Bihr , Abigail Tague , Gretchen Willwerth , Matthew Nault , Justeen Hyde","doi":"10.1016/j.explore.2024.103109","DOIUrl":"10.1016/j.explore.2024.103109","url":null,"abstract":"<div><h3>Objectives</h3><div>To understand ways in which the Personal Health Inventory (PHI), a tool to prompt reflection on what matters most and status in 8 components of health and well-being, can be used to inform care of homeless veterans entering a Mental Health Residential Rehabilitation Treatment Program, at individual and programmatic levels.</div></div><div><h3>Methods</h3><div>Mixed method study was conducted at one residential treatment program. Quantitative data was collected from the PHI (n=64) and was analyzed using descriptive statistics. Qualitative data was collected from the PHI and semi-structured staff interviews (n=9) and was analyzed using thematic analysis.</div></div><div><h3>Results</h3><div>Approximately half of veterans entering the program between January and September, 2023 completed a PHI. Themes for what matters most included: 1) reconnecting with family, 2) improving health, and 3) self-discovery. Structured responses to the 8 areas of health indicated lowest satisfaction with: 1) relationships, 2) personal development, and 3) surroundings. Staff interviews indicated knowing where veterans are most and least satisfied helped inform goal setting and connection to resources. Population-level analysis of information from the PHI prompted reflection on existing programming.</div></div><div><h3>Conclusions</h3><div>Residential treatment programs may benefit from incorporating brief instruments like the PHI to inform individual care and overall program offerings.</div></div>","PeriodicalId":50459,"journal":{"name":"Explore-The Journal of Science and Healing","volume":"21 1","pages":"Article 103109"},"PeriodicalIF":1.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142933370","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effects of acupressure on pain and first mobilisation distance after caesarean section: A double-blind randomised controlled study","authors":"Aslıhan Aksu , Tuğba Çam-Yanık , Filiz Değirmenci , Duygu Vefikuluçay-Yılmaz , Gülay Altun-Uğraş , Mürşide Çevikoğlu-Kıllı","doi":"10.1016/j.explore.2024.103102","DOIUrl":"10.1016/j.explore.2024.103102","url":null,"abstract":"<div><h3>Background</h3><div>Postoperative pain is one of the most common problems after caesarean section (CS). Pain reduction and effective mobilisation after CS positively affect maternal and infant health.</div></div><div><h3>Aim</h3><div>This study aimed to determine the effects of acupressure applied to women after CS on pain intensity and first mobilisation distance.</div></div><div><h3>Methods</h3><div>The sample of this prospective, two-armed (1:1), double-blind randomised controlled clinical trial consisted of 64 women undergoing CS (32 acupressure and 32 placebo acupressure group). The data were analysed using descriptive statistics, chi-square test, independent-groups <em>t</em>-test, Mann–Whitney U test, repeated-measures two-way analysis of variance (ANOVA) and simple main-effects analysis.</div></div><div><h3>Results</h3><div>Findings showed statistically significant group effects (<em>F</em> = 19.32, <em>p</em><.001), time effects (<em>F</em> = 27.67, <em>p</em><.001), and group- and time-interaction effects (<em>F</em> = 26.60, <em>p</em><.001) on postoperative pain after CS. In the acupressure group, the VAS scores were lower at 1 min, 2 h and 4 h after the intervention compared to before the intervention (<em>p</em><.001; <em>p</em><.001; <em>p</em>=.001, respectively). In the placebo group, the VAS score at 1 min after the application decreased, increasing at 2 h and 4 h, but these changes were not significant (<em>p</em>>.05). The first mobilisation distance of the acupressure group was significantly longer than that of the placebo group (<em>p</em><.001).</div></div><div><h3>Conclusion</h3><div>Acupressure applied to the SP6, P6 and LI4 points was an effective nursing intervention for pain control and mobilisation after CS. Considering the significant impact of pain after CS on maternal and infant health, nurses should include acupressure, which is easy to apply, cost-effective, and efficacious, in postpartum care.</div></div>","PeriodicalId":50459,"journal":{"name":"Explore-The Journal of Science and Healing","volume":"21 1","pages":"Article 103102"},"PeriodicalIF":1.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142899417","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Humanity's precognition: Climate change and the decline of democracy","authors":"Stephan A. Schwartz","doi":"10.1016/j.explore.2024.103104","DOIUrl":"10.1016/j.explore.2024.103104","url":null,"abstract":"","PeriodicalId":50459,"journal":{"name":"Explore-The Journal of Science and Healing","volume":"21 1","pages":"Article 103104"},"PeriodicalIF":1.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142899716","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"You….. And Me…..and a Cup of Tea: Eight insights we've gleaned from enlightened masters","authors":"Jeb Barton , Marjorie Woollacott","doi":"10.1016/j.explore.2024.103096","DOIUrl":"10.1016/j.explore.2024.103096","url":null,"abstract":"<div><div>This Reflection piece offers eight insights that have been gleaned from enlightened masters related to the nature of consciousness, awareness and experience. These insights are elucidated in ways that can help in the evaluation of the usefulness of our values and beliefs, and how these dictate the way we respond to our life experiences. In this way the essay points to the importance of cultivating and refining one's own awareness because it is the level of our awareness that controls the flow of creativity and experience, both into and out of our lives.</div></div>","PeriodicalId":50459,"journal":{"name":"Explore-The Journal of Science and Healing","volume":"21 1","pages":"Article 103096"},"PeriodicalIF":1.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142848270","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Summary of a Cochrane review: Meditation for the primary and secondary prevention of cardiovascular disease","authors":"Getrude Mphwanthe","doi":"10.1016/j.explore.2024.103105","DOIUrl":"10.1016/j.explore.2024.103105","url":null,"abstract":"","PeriodicalId":50459,"journal":{"name":"Explore-The Journal of Science and Healing","volume":"21 1","pages":"Article 103105"},"PeriodicalIF":1.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142903883","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}