Biological and Clinical Sciences Research Journal最新文献_第8页

IMPACT OF MALNUTRITION ON PEDIATRIC HEART FAILURE ANALYZING Z-SCORES AT PRESENTATION 营养不良对小儿心力衰竭的影响分析发病时的 Z 值

Biological and Clinical Sciences Research Journal Pub Date : 2024-03-22 DOI: 10.54112/bcsrj.v2024i1.767

ZA Yousafzai, S. Ilyas, Z. Nawab, .. Abdullah

{"title":"IMPACT OF MALNUTRITION ON PEDIATRIC HEART FAILURE ANALYZING Z-SCORES AT PRESENTATION","authors":"ZA Yousafzai, S. Ilyas, Z. Nawab, .. Abdullah","doi":"10.54112/bcsrj.v2024i1.767","DOIUrl":"https://doi.org/10.54112/bcsrj.v2024i1.767","url":null,"abstract":"Pediatric heart failure represents a critical health concern characterized by the heart's inability to effectively pump blood, often resulting from congenital heart defects, myocarditis, and cardiomyopathies. Malnutrition has emerged as a recognized comorbidity in pediatric heart failure, significantly impacting patient outcomes. This study aimed to investigate the relationship between malnutrition and pediatric heart failure by analyzing Z-scores at presentation to guide targeted interventions and improve patient management. The study employed a retrospective observational design and was conducted at the Department of Pediatric Cardiology, Lady Reading Hospital, Peshawar, from January 2023 to January 2024. A total of 764 pediatric patients with heart failure were included in the analysis. Nutritional status was assessed using weight and height measurements, and Z-scores were calculated based on WHO Child Growth Standards. Data analysis was performed using IBM SPSS version 22. Results revealed varying degrees of malnutrition among pediatric heart failure patients, with 62.8% classified as severely malnourished, 28.4% as moderately malnourished, and 8.8% as mildly malnourished. The calculated Z-score of -3.2 indicated significant malnutrition among the study population. Furthermore, a negative correlation (r = -0.32, p < 0.001) between Z-score and left ventricular ejection fraction was observed, suggesting a link between malnutrition severity and cardiac dysfunction. These findings underscore the high prevalence of malnutrition among pediatric heart failure patients and its substantial impact on outcomes. Early nutritional assessment and intervention are crucial for optimizing patient care and enhancing outcomes in children with heart failure. Collaborative, multidisciplinary approaches that integrate cardiac and nutritional management strategies can comprehensively address the diverse needs of this vulnerable population.","PeriodicalId":504575,"journal":{"name":"Biological and Clinical Sciences Research Journal","volume":" 12","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140217697","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

FREQUENCY OF TORCH INFECTION AMONG CONGENITAL CATARACT PATIENTS 先天性白内障患者火炬感染的频率

Biological and Clinical Sciences Research Journal Pub Date : 2024-03-22 DOI: 10.54112/bcsrj.v2024i1.758

SA Bhutto, AA Abro, NA Katpar, DD Shaikh, SA Abbasi, PA Gul

{"title":"FREQUENCY OF TORCH INFECTION AMONG CONGENITAL CATARACT PATIENTS","authors":"SA Bhutto, AA Abro, NA Katpar, DD Shaikh, SA Abbasi, PA Gul","doi":"10.54112/bcsrj.v2024i1.758","DOIUrl":"https://doi.org/10.54112/bcsrj.v2024i1.758","url":null,"abstract":"The objective of this descriptive cross-sectional study was to determine the frequency of TORCH infections among congenital cataract patients. The study was conducted at Shaheed Mohtarma Benazir Bhutto Medical University Larkana, from September 22, 2021, to March 21, 2022. Patients meeting the inclusion criteria, including those diagnosed with congenital cataracts and TORCH infection within the age range of one day to ten years, were included after obtaining informed consent from their guardians. A slit lamp examination was performed to identify lens opacities indicative of congenital cataracts. Subsequently, patients with congenital cataracts were sent for laboratory investigation. TORCH infections were diagnosed based on IgM levels and clinical manifestations specific to each pathogen. The results revealed that the age range of the patients included in the study was one day to ten years, with a mean age of 17.9 ± 21.8 months. Of the 85 patients with congenital cataracts, 36 (42.5%) were male, and 49 (57.5%) were female. Interestingly, TORCH infection was identified in 17 (19.6%) patients with congenital cataracts, while the remaining patients showed no evidence of TORCH infection. In conclusion, TORCH pathogens, particularly cytomegalovirus and rubella virus, were found to be frequent causative agents of congenital cataracts. These findings highlight the importance of early diagnosis and management of TORCH infections in patients with congenital cataracts to prevent visual impairment and other associated complications.","PeriodicalId":504575,"journal":{"name":"Biological and Clinical Sciences Research Journal","volume":" 13","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140219049","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

BURDEN OF ANEMIA AND ASSOCIATED FACTORS AMONG PREGNANT WOMEN AT KAUSAR HOSPITAL MOTHER AND CHILD HEALTH CARE CENTRE KHAIRPUR MIR’S, PAKISTAN 巴基斯坦 KHAIRPUR MIR'S KAUSAR 医院母婴保健中心孕妇的贫血负担及相关因素

Biological and Clinical Sciences Research Journal Pub Date : 2024-03-21 DOI: 10.54112/bcsrj.v2024i1.701

N. Balouch, S. Waheed, T. Waheed, KH Memon

{"title":"BURDEN OF ANEMIA AND ASSOCIATED FACTORS AMONG PREGNANT WOMEN AT KAUSAR HOSPITAL MOTHER AND CHILD HEALTH CARE CENTRE KHAIRPUR MIR’S, PAKISTAN","authors":"N. Balouch, S. Waheed, T. Waheed, KH Memon","doi":"10.54112/bcsrj.v2024i1.701","DOIUrl":"https://doi.org/10.54112/bcsrj.v2024i1.701","url":null,"abstract":"Anemia is the condition in which hemoglobin level may become lower than normal <11.0g/dl. According to an estimate, about one-third of the world's population (over 2 billion) are anemic. The study aimed to determine the Prevalence of anemia and associated factors among pregnant women at Kausar Hospital Mother and Child Health Care Centre Khairpur Mir’s, Sindh, Pakistan. The cross-sectional study was conducted from August to December 2019. A total number of 100 pregnant women were randomly included in this study. A predesigned questionnaire was filled out by face-to-face interviews consisting of socio-demographic characteristics, including Name, Age, gestational age, educational level, occupation, and monthly income. Anemia was classified as per World Health Organisation (WHO) criteria. The prevalence rate of Anemia in the present study was 69%. Minimum Haemoglobin levels were observed at 5.6 g/dL, and maximum Haemoglobin levels were observed at 12.4 g/dL with an average Haemoglobin of 10.05 g/dL ±1.44. Among them, 49% had mild anemia, 17% moderate anemia, and 3% severe anemia. At the same time, the patients were divided into age groups of 15-20 years, 21 to 25 years, 26 to 30 years, and 31-35 years to compare Anemia or Haemoglobin levels. Results showed a higher prevalence of anemia between the ages of 26 and 30. The minimum age was observed to be 20 years and a maximum of 35 years, with an average age of 28.12 years ±2.5 years. It was observed that the prevalence of Anemia was higher in 7-9 gestational months; socio-economic factors (Age, Gestational month, Number of children, and income source) showed significant association with Anemia. The present study concludes that the Prevalence of Anemia and Associated Factors among Pregnant Women at Kausar Hospital was 69%. Among them, 49% had mild anemia, 17% moderate anemia, and 3% severe anemia.","PeriodicalId":504575,"journal":{"name":"Biological and Clinical Sciences Research Journal","volume":" 105","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140221355","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

DRUG AND ALCOHOL USE IN ORTHOPAEDIC TRAUMA PATIENTS: A PROSPECTIVE STUDY 骨科创伤患者的药物和酒精使用情况：前瞻性研究

Biological and Clinical Sciences Research Journal Pub Date : 2024-03-20 DOI: 10.54112/bcsrj.v2024i1.757

MU Farooque, K. Anwar, S. Hussain, MR Kifayatullah, A. Ghaffar, J. Ahmed

{"title":"DRUG AND ALCOHOL USE IN ORTHOPAEDIC TRAUMA PATIENTS: A PROSPECTIVE STUDY","authors":"MU Farooque, K. Anwar, S. Hussain, MR Kifayatullah, A. Ghaffar, J. Ahmed","doi":"10.54112/bcsrj.v2024i1.757","DOIUrl":"https://doi.org/10.54112/bcsrj.v2024i1.757","url":null,"abstract":"The objective of this study is to prospectively investigate the prevalence, patterns, and correlates of drug and alcohol use among orthopaedic trauma patients. After the ethical approval from the institutional review board, this cross-sectional study was conducted at Jinnah Postgraduate Medical Center from 01/09/23 to 29/02/24. Baseline data was collected upon admission and included demographic information (such as age and gender) and a comprehensive assessment of substance use history. Substance use was assessed using validated screening tools, including the Alcohol Use Disorders Identification Test (AUDIT) and the Drug Abuse Screening Test (DAST), to capture patterns of alcohol and drug use, frequency, duration, and any previous treatment history for substance use disorders. In the present study, the prevalence of drug and alcohol use among the orthopedic traumatic participants was (40%). Among them, the majority (51%) were using alcohol, followed by marijuana use (25%), and then cocaine (11%). The means of hospital stay of participants in substance non-users and users (2.4±0.8 vs. 6.83±1.1; P<0.0001). Pre-injury alcohol and drug use appear to correlate with extended hospital stays among patients with traumatic orthopaedic injuries.","PeriodicalId":504575,"journal":{"name":"Biological and Clinical Sciences Research Journal","volume":"5 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140227258","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

ASSESSMENT OF ANTERIOR CHAMBER ANGLE ON ANTERIOR SEGMENT OPTICAL COHERENCE TOMOGRAPHY IN PATIENTS WITH ANGLE CLOSURE GLAUCOMA AND ANGLE CLOSURE SUSPECTS 通过前节光学相干断层扫描评估闭角型青光眼患者和闭角型青光眼疑似患者的前房角

Biological and Clinical Sciences Research Journal Pub Date : 2024-03-19 DOI: 10.54112/bcsrj.v2024i1.759

SA Bhutto, AA Leghari, NA Katpar, Z. Gopang, Dyd Shaikh, PA Gul

{"title":"ASSESSMENT OF ANTERIOR CHAMBER ANGLE ON ANTERIOR SEGMENT OPTICAL COHERENCE TOMOGRAPHY IN PATIENTS WITH ANGLE CLOSURE GLAUCOMA AND ANGLE CLOSURE SUSPECTS","authors":"SA Bhutto, AA Leghari, NA Katpar, Z. Gopang, Dyd Shaikh, PA Gul","doi":"10.54112/bcsrj.v2024i1.759","DOIUrl":"https://doi.org/10.54112/bcsrj.v2024i1.759","url":null,"abstract":"The objective of this cross-sectional study was to determine the anterior chamber angle using anterior segment optical coherence tomography (AS-OCT) in patients diagnosed with angle closure glaucoma and angle closure suspects. The research was conducted at Shaheed Mohtarma Benazir Bhutto Medical University Larkana, spanning from March 3, 2022, to June 30, 2023. Patients meeting the inclusion criteria and diagnosed with primary angle-closure glaucoma (PACG) were enrolled in the study after obtaining informed consent. The procedure, risks, and benefits of the study were explained to the patients before obtaining consent. AS-OCT was utilized to evaluate patients suspected of primary angle closure and those with confirmed primary angle closure. The results revealed a mean age of 56.21 ± 12.31 years among the study participants, with a confidence interval of 55.04 to 57.38. The mean duration of primary angle closure glaucoma was 22.52 ± 10.98 months, with a confidence interval of 21.47 to 23.57. Of the 423 patients included in the study, 219 (52%) were male, and 204 (48%) were female. Primary angle closure suspect and primary angle closure were observed in 47 (11%) and 44 (10%) patients, respectively. In conclusion, older age, higher central corneal thickness (CCT), and shorter axial length or presence of hyperopia were identified as important independent predictors of suspicion of primary angle closure and primary angle closure. These findings underscore the significance of thorough assessment and monitoring of these parameters in patients at risk of angle closure glaucoma.","PeriodicalId":504575,"journal":{"name":"Biological and Clinical Sciences Research Journal","volume":"66 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140229964","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

COMPARISON OF THE VARIABILITY OF RECOVERY PROFILE AND HEMODYNAMIC EFFECTS OF NEUROMUSCULAR BLOCKADE WITH CISATRACURIUM VERSUS ATRACURIUM 顺式阿曲库铵与阿曲库铵神经肌肉阻断术的恢复曲线和血流动力学效应的变异性比较

Biological and Clinical Sciences Research Journal Pub Date : 2024-03-19 DOI: 10.54112/bcsrj.v2024i1.761

A. Siddiqui, S. Raza, S. Shafqat, S. Zehra, S. Bozdar, MN Munir

{"title":"COMPARISON OF THE VARIABILITY OF RECOVERY PROFILE AND HEMODYNAMIC EFFECTS OF NEUROMUSCULAR BLOCKADE WITH CISATRACURIUM VERSUS ATRACURIUM","authors":"A. Siddiqui, S. Raza, S. Shafqat, S. Zehra, S. Bozdar, MN Munir","doi":"10.54112/bcsrj.v2024i1.761","DOIUrl":"https://doi.org/10.54112/bcsrj.v2024i1.761","url":null,"abstract":"A randomized controlled trial was conducted at the Main Operation Theatre of Jinnah Postgraduate Medical Centre (JPMC) in Karachi to compare the recovery profile and hemodynamic effects of cisatracurium and atracurium among patients undergoing laparoscopic cholecystectomy. The study was conducted from 20th July 2019 to 19th January 2020 and included 68 patients aged between 20 to 50 years undergoing elective laparoscopic cholecystectomy under general anesthesia. Patients with a history of allergy to the study drugs, neuromuscular, pulmonary, renal, or hepatic diseases, smoking, pregnancy, or breastfeeding, and those on preoperative medication such as antipsychotics, aminoglycosides, steroids, or neuroleptics were excluded. The patients were randomly divided into two groups. In Group 1, comprising 34 patients, cisatracurium (0.2 mg/kg) was administered, whereas in Group 2, also with 34 patients, atracurium (0.5 mg/kg) was given. Neuromuscular blocking agents were administered three minutes before intubation. The primary outcomes measured were the recovery profile and hemodynamic effects. In Group 1 (cisatracurium), the baseline mean arterial pressure (MAP) was recorded as 98.40 ± 8.02 mmHg, which increased to 112.20 ± 8.88 mmHg before intubation, resulting in a change of 13.56 ± 5.59 mmHg. In contrast, in Group 2 (atracurium), the baseline MAP was 94.10 ± 7.91 mmHg, which rose to 109.07 ± 8.35 mmHg before intubation, indicating a change of 16.50 ± 4.38 mmHg. The study concluded that cisatracurium is more effective in exhibiting neuromuscular blocking properties than atracurium in patients undergoing laparoscopic cholecystectomy under general anesthesia.","PeriodicalId":504575,"journal":{"name":"Biological and Clinical Sciences Research Journal","volume":"59 10","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140228928","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

THE ANATOMY OF BONE HEALING: BONE REGENERATION IN ORTHOPEDIC MEDICINE 骨愈合的解剖学：骨科医学中的骨再生

Biological and Clinical Sciences Research Journal Pub Date : 2024-03-18 DOI: 10.54112/bcsrj.v2024i1.754

Qua Khan, F. Malik, Saz Naqvi, T. Kausar, T. Raza, A. Mansoor

{"title":"THE ANATOMY OF BONE HEALING: BONE REGENERATION IN ORTHOPEDIC MEDICINE","authors":"Qua Khan, F. Malik, Saz Naqvi, T. Kausar, T. Raza, A. Mansoor","doi":"10.54112/bcsrj.v2024i1.754","DOIUrl":"https://doi.org/10.54112/bcsrj.v2024i1.754","url":null,"abstract":"Bone regeneration is a physiological bone formation process involved in routine fracture healing and continuous remodeling throughout adult life. The study's main objective is to determine the role of orthopedic medicines in bone regeneration and healing process. This retrospective study was conducted in a public hospital in Karachi, Pakistan, from February 2023 to June 2023. The study aimed to collect data from 120 bone fracture patients and evaluate the progression of bone healing to identify critical determinants of successful regeneration. Clinical assessments, radiological imaging, and histopathological analyses were conducted to achieve the study's objectives. The study collected data from 120 patients, with a mean age of 45.21±12.3 years. Of these, 70 were male and 50 were female. Upper extremities accounted for 40% of fractures, lower extremities 30%, and axial skeleton 30%. Simple fractures accounted for 50% of cases, while comminuted fractures represented 30% and open fractures 20%. There was a strong positive correlation between fracture severity and the time required for radiographic union, with a correlation coefficient (r) of 0.65 (p < 0.001). Additionally, biomarkers of bone turnover exhibited a moderate positive correlation with radiological healing, with a correlation coefficient (r) of 0.45 (p = 0.003). The study concludes that orthopedic interventions have a high success rate in achieving satisfactory outcomes, with the majority of patients experiencing successful bone healing and restoration of function.","PeriodicalId":504575,"journal":{"name":"Biological and Clinical Sciences Research Journal","volume":"241 8","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140233693","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

SEDATION DEPTH DURING CRITICAL CARE TRANSPORT AND HOSPITALIZATION 重症监护转运和住院期间的镇静深度

Biological and Clinical Sciences Research Journal Pub Date : 2024-03-18 DOI: 10.54112/bcsrj.v2024i1.756

M. Haroon, .. Sulaiman, MJ Khan, I. Haq, S. Ahmad, S. Malik

{"title":"SEDATION DEPTH DURING CRITICAL CARE TRANSPORT AND HOSPITALIZATION","authors":"M. Haroon, .. Sulaiman, MJ Khan, I. Haq, S. Ahmad, S. Malik","doi":"10.54112/bcsrj.v2024i1.756","DOIUrl":"https://doi.org/10.54112/bcsrj.v2024i1.756","url":null,"abstract":"The purpose of this study was to determine the differences in attained levels of sedation both within intensive care units and collectively regarding overall outcomes when patients were transported outside a hospital either pre-hospital or while being inter-facility transfer by different critical care agencies, having been exposed to light versus deep quality of anaesthesia. After the ethical approval from the institutional review board, this cross-sectional study was conducted at Khyber Teaching Hospital from 01/06/22 to 31/12/22. The primary outcome measure was the relation of starting deep sedation during transport to deep sedation in the first 48 hours after admission (defined as RASS -3 and less). Secondary outcomes included mechanical ventilation duration, inpatient mortality, total hospital stay length of ICU, and delirium within 48 h; coma may also be observed. Final transport RASS in both the study groups was-4.43±0.49 and-1.5±0.5 (p <0.0001). Mean Hospital duration in both study groups was 13.01±4.8 and 35±5.9 days (p<0.0001). A high percentage of inpatient mortality, delirium, and coma cases was seen in the deep sedation group (p<0.0001). The transfer of patient care from the transport team to the hospital team presents a chance to potentially interrupt the progress of treatment and reassess decisions regarding sedation.","PeriodicalId":504575,"journal":{"name":"Biological and Clinical Sciences Research Journal","volume":"279 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140233642","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

CHALLENGES FACED BY NURSING STUDENTS IN ONLINE EDUCATION DURING THE COVID-19 PANDEMIC 科维德-19 大流行期间护理专业学生在在线教育中面临的挑战

Biological and Clinical Sciences Research Journal Pub Date : 2024-03-18 DOI: 10.54112/bcsrj.v2024i1.755

B. Farid, M. Zafar, K. Rasheed, H. Arshad

{"title":"CHALLENGES FACED BY NURSING STUDENTS IN ONLINE EDUCATION DURING THE COVID-19 PANDEMIC","authors":"B. Farid, M. Zafar, K. Rasheed, H. Arshad","doi":"10.54112/bcsrj.v2024i1.755","DOIUrl":"https://doi.org/10.54112/bcsrj.v2024i1.755","url":null,"abstract":"Amid the COVID-19 pandemic, the transition to online education has posed significant challenges for nursing students worldwide. This study explores the multifaceted obstacles encountered during this shift and aims to provide insights for improving online nursing education. Utilizing a descriptive cross-sectional quantitative research design, data was collected from 73 final-year nursing students at Saida Waheed FMH College of Nursing, Lahore, using a structured questionnaire. The questionnaire assessed various domains, including learning effectiveness, software proficiency, instructor support, communication, course design, and psychosocial experiences. The results revealed a spectrum of student experiences, ranging from perceived benefits to substantial challenges adapting to online learning. While some students reported proficiency in online education tools, others faced difficulties navigating technology and accessing course materials. Instructor support emerged as a critical factor influencing students' satisfaction and learning outcomes, with clear communication and timely feedback paramount. Additionally, challenges related to course design and psychosocial experiences significantly impacted students' engagement and motivation. By comparing these findings with previous research, common themes and areas for improvement in online nursing education were identified. The study underscores the importance of targeted interventions to address technological barriers, enhance instructional support, optimize course design, and prioritize students' psychosocial well-being in online learning environments. Ultimately, these insights can inform the development of effective strategies to enhance the quality and effectiveness of online nursing education programs.","PeriodicalId":504575,"journal":{"name":"Biological and Clinical Sciences Research Journal","volume":"65 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140234290","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

EFFECTS OF ANTICOAGULANTS ON BLOOD CELLS MORPHOLOGY AND BIOCHEMISTRY 抗凝剂对血细胞形态和生物化学的影响

Biological and Clinical Sciences Research Journal Pub Date : 2024-03-14 DOI: 10.54112/bcsrj.v2024i1.663

A. Arshad, A. Safdar, M. Atif, H. Hussain, M. Waqas, S. Mahmood

{"title":"EFFECTS OF ANTICOAGULANTS ON BLOOD CELLS MORPHOLOGY AND BIOCHEMISTRY","authors":"A. Arshad, A. Safdar, M. Atif, H. Hussain, M. Waqas, S. Mahmood","doi":"10.54112/bcsrj.v2024i1.663","DOIUrl":"https://doi.org/10.54112/bcsrj.v2024i1.663","url":null,"abstract":"Blood is a particular type of connective tissue that majorly contains red blood cells (RBCs), white blood cells (WBCs), and platelets (Plts). Anticoagulants are used to preserve the fluidity of blood and retard morphological changes in blood cells. Anticoagulants like EDTA, heparin, sodium citrate, and CPDA-1 are used. However, these anticoagulants also have some disadvantages, summarized in this review. This chemical causes the lysis of many cells, including RBCs, and some of them, like EDTA, cause agglutination of platelets, which not only causes a decrease in platelet count but also causes a spurious increase in WBC count. These substances also alter the shapes of various cells present in blood. RBCs and platelets may become spherical from the normal biconcave disc and plate-like structures. Commonly used anticoagulants contribute to alterations of many hematological parameters, including hematocrit, hemoglobin concentration, and packed cell volume of RBCs. Certain chemicals used in anticoagulant solutions, such as potassium and sodium in EDTA solution, make the blood unsuitable for determining these electrolytes in the sample. They also induce many changes in the biochemical composition of the sample. The most affected biochemical changes are observed in 2,3-DPG, D-dimer concentration, blood gas estimation, and cytokine levels. As they contain different chemicals, they have varying pH, so they alter blood pH.","PeriodicalId":504575,"journal":{"name":"Biological and Clinical Sciences Research Journal","volume":"12 19","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140242040","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0