International Journal of Research and Review最新文献

{"title":"An Aggressive Sinonasal Mass","authors":"Madhumita Mukhopadhyay, Binata Bandopadhyay, Subhamoy Saha","doi":"10.52403/ijrr.20240715","DOIUrl":"https://doi.org/10.52403/ijrr.20240715","url":null,"abstract":"INTRODUCTION: Sinonasal teratocarcinosarcoma (SNTCS) is an extremely rare aggressive malignant tumor arising in the sinonasal tract, often confused with other sinonasal tumors. It is more common in adult males. These tumors are often difficult to diagnose because of their diverse histology.\u0000CASE REPORT: We are presenting a case of right sided SNTCS in a 38-year-old male patient. The patient had a history of right sided nasal obstruction associated with recurrent episodes of epistaxis for last 3 months. On examination, a solid mass was noted in the right nasal cavity that was greyish black in colour, irregularly shaped, brittle, exhibits localized surface necrosis and bleeds easily on touch. Microscopic examination revealed an admixture of carcinomatous (glands, non keratinized squamous epithelia), sarcomatous (atypical spindle cells, smooth muscle), primitive neuroectodermal and teratoid elements (immature squamous and clear cell nests).\u0000CONCLUSION: SNTCSs are highly aggressive tumors with poor prognosis. Majority of the patients do not survive beyond 3 years. Complete excision and extensive sampling are necessary for their diagnosis. However, because of their aggressive nature, aggressive treatment approach of surgery with adjuvant chemo-radiation is more beneficial than surgical excision alone.\u0000\u0000Keywords: adeno-squamous carcinoma, epistaxis, immunohistochemistry, olfactory neuroblastoma, paranasal sinus, sinonasal mass, teratocarcinosarcoma","PeriodicalId":504363,"journal":{"name":"International Journal of Research and Review","volume":"61 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141653687","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Representation of Soil-Transmitted Helminth Eggs on Fingernails of Children in Orphanages in the City of Padang on October-December 2023","authors":"Siti Nadira Ramadhani, Selfi Renita Rusjdi, Rizki Rahmadian","doi":"10.52403/ijrr.20240701","DOIUrl":"https://doi.org/10.52403/ijrr.20240701","url":null,"abstract":"Soil-transmitted helminth (STH) infection is one of the neglected tropical diseases in which preschool-age and school-age children had the highest number of the prevalence. The spread of STH infection can be caused by poor nail hygiene, especially in shared facilities such as orphanage.\u0000This study was a descriptive study with primary data from Al-Falah Orphanage, Anak Mentawai Gurun Laweh Orphanage, and Yayasan Kanzul Ulum Pasia Nan Tigo on October to December 2023. The sampling technique in this study was purposive sampling with 123 total samples. All samples were examined by direct microscopic examination with direct sedimentation method.\u0000The study found that from 123 samples, 1.6% samples were contaminated by Ascaris lumbricoides eggs and 0.8% samples were contaminated by hookworm eggs.\u0000It can be concluded that STH eggs were identified on fingernails of children in orphanages in the city of Padang which contributed as one of STH infection transmission factor. Therefore, promotive and preventive actions might be needed to prevent STH infection in orphanage children.\u0000\u0000Keywords: Nail hygiene, STH infection, orphanage children","PeriodicalId":504363,"journal":{"name":"International Journal of Research and Review","volume":"46 13","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141654619","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Influence of Conflict Between Ideas and Discrepant Event on Conceptual Changes in Physics Learning","authors":"Partono, Eko Prihandono, Friska Octavia Rosa","doi":"10.52403/ijrr.20240708","DOIUrl":"https://doi.org/10.52403/ijrr.20240708","url":null,"abstract":"Individuals when faced with a confrontation situation or a new idea that is unusual in everyday life, then in their cognitive structure there will be a conflict so that doubts arise why the existing conception is not appropriate and whether to change the previous conception according to the new situation or idea. This study aims to test the effectiveness of the idea confrontation strategy in physics learning in improving high school students' understanding of the effect of force on the motion of objects. The research method used is a quasi-experimental with a one group pretest-posttest design applied to one group. The research sample was 40 first-grade high school students where the type of confrontation source was generated by two categories, namely conflict between ideas and discrepant events. The conclusion obtained is that the idea confrontation strategy can significantly improve overall student learning outcomes but cannot differentiate between ability groups, can correct students' misconceptions about the effect of force on the motion of objects both based on the target concept and the type of concept, and can encourage changes in student conceptions.\u0000\u0000Keywords: conflict between ideas, discrepant event, Conceptual Change, Physics Learning.","PeriodicalId":504363,"journal":{"name":"International Journal of Research and Review","volume":"16 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141653513","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development of SSCS Model Learning Tools on Digestive System Topic to Train Students' Creative Thinking Skills","authors":"Wilinda A. Datau, Masra Latjompoh, Margaretha Solang","doi":"10.52403/ijrr.20240709","DOIUrl":"https://doi.org/10.52403/ijrr.20240709","url":null,"abstract":"The 21st century requires students to develop various skills and knowledge. One essential skill to be fostered is creative thinking. The digestive system topic is quite complex and abstract, which results in students having difficulty understanding it. Observations at SMAN 8 Gorontalo and SMAN 1 Gorontalo Senior High School revealed that students' creative thinking skills, including fluency and originality, are still lacking and need to be trained and improved. This study aims to produce learning tools using the SSCS model for digestive system topics with valid, practical, and effective criteria. The developed learning tools include a teaching module, student worksheets, and creative thinking question sheets. The research method used was qualitative descriptive analysis and quantitative data calculation with the Borg and Gall development model. The validity analysis results showed that the teaching module scored 89% (valid category), student worksheets 92% (valid category), and the creative thinking skills test 89%. Practicality analysis results indicated that teacher activity scored an average of 95% (excellent), and student activity 92% (excellent). The effectiveness analysis of the creative thinking test showed a pre-test score of 50% and a post-test score of 88%. Student response results were 88% (excellent). These data indicate that the learning tools developed with the SSCS model can train students' creative thinking skills.\u0000\u0000Keywords: Learning Tools, SSCS, Creative Thinking","PeriodicalId":504363,"journal":{"name":"International Journal of Research and Review","volume":"19 12","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141653646","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Role of Families in Social Resilience of Children of Small Widows of Indramayu Descent (RCTI) in Indramayu Regency","authors":"Inayah, P. Hardati, Gunawan","doi":"10.52403/ijrr.20240705","DOIUrl":"https://doi.org/10.52403/ijrr.20240705","url":null,"abstract":"The family is the first place for the formation of personality in children. In the formation of children's personalities, families must have a good parenting pattern for their children in order to create social intelligence, social resilience and good social relations in society. The purpose of the study focuses on finding the role of family in the social resilience of RCTI children with functional structural theory analysis. The method used is qualitative case studies. The research location is in Pranggong Village, Ararahan District, Indramayu Regency. The results of this study found the role of the family in shaping the social resilience of family children in applying rules and supervision to RCTI children in the form of family norms that are made such as: rules to play until late at night and attitudes in social media. In addition to regulations and supervision, the family applies social and religious values that exist in society. The application of social religious values taught to RCTI children is to participate in social and religious activities such as: Mapag Sri tradition, reciting the Qur'an, recitation and other social and religious activities.\u0000\u0000Keywords: Family Role, Social Resilience, RCTI Children","PeriodicalId":504363,"journal":{"name":"International Journal of Research and Review","volume":"29 9","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141653827","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analysis of the Effect of Competency, Independence, Audit Planning, Audit Supervision, And Auditor Reporting on Audit Quality in Medan Inspectorate with Motivation as a Moderating Variable","authors":"Sanni Rolina Sipayung, Abdillah Arif Nasution, Rujiman","doi":"10.52403/ijrr.20240706","DOIUrl":"https://doi.org/10.52403/ijrr.20240706","url":null,"abstract":"This quantitative study aims to analyze the effect of auditor competencies, independence, audit planning, supervision, and reporting on audit quality moderated by the auditor's work motivation. The research population is 118 people, and the determination of samples was done using the total sampling method, so there were 118 samples. Data collection methods used questionnaires, and data analysis used the Smart PLS program.\u0000The results showed that auditors' competency, independence, and reporting positively and significantly affected audit quality. At the same time, audit planning and audit supply have no effect. Work motivation can moderate the effect of audit independence, planning, and supervision of audit quality. Work motivation cannot moderate the effect of auditor competencies and reporting on audit quality. To the Head of the Medan City Inspectorate Office, it is recommended that attention be paid to these factors so that the quality of financial statements can be further improved.\u0000\u0000Keywords: auditor competence, auditor independence, audit planning, audit supervision, and audit auditor reporting audit","PeriodicalId":504363,"journal":{"name":"International Journal of Research and Review","volume":"19 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141653759","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Implementation of the Snakes and Ladders Educational Game as a Landslide Mitigation Education Media and Its Effect on Student Knowledge","authors":"Sinta Kusumaningjati, Ni’am Khakiki, Risma Martiyani","doi":"10.52403/ijrr.20240704","DOIUrl":"https://doi.org/10.52403/ijrr.20240704","url":null,"abstract":"MA Riyadhus Sholihin Al Islamy not yet utilize learning media in the material disaster, namely learning uses the lecture method with textbooks and this creates learning boring. Apart from that, MA Riyadhus Sholihin Al Islamy located in the area Ward Ngijo Subdistrict Gunungpati has potential disaster land landslide marked with levels high rainfall and vulnerability​ high landslides.​ The aim of this research is first know implementation of educational games snake stairs as a medium for mitigating land disasters landslide for student. Second aim analyze influence of educational games snake stairs as a medium for mitigating land disasters landslide on students' knowledge. The type of research used is descriptive quantitative, with data collection methods of observation, unstructured interviews, documentation and using pretest-posttest. The results of this research are that students can play educational games by being able to answer questions about landslide disaster material well. Then the influence of the snakes and ladders educational game can also increase students' knowledge regarding landslide disaster mitigation and can also trigger active learning in students so that the learning process is more interesting and not boring.\u0000\u0000Keywords: Educational games, outreach media, landslide mitigation, level of knowledge","PeriodicalId":504363,"journal":{"name":"International Journal of Research and Review","volume":"49 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141653083","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"hWJ-MSC Reduces IL-1β Gene Expression in Alzheimer's Rat Models","authors":"Nita Afriani, E. Darwin, Hirowati Ali","doi":"10.52403/ijrr.20240702","DOIUrl":"https://doi.org/10.52403/ijrr.20240702","url":null,"abstract":"Objective: This study aims to study effect of Wharton's Jelly MSCs regulate IL-1β gene expression and to evaluate the potential of these MSCs as an innovative therapy for Alzheimer's disease;\u0000Method: This study was post test only control group design. Male Wistar rats were divided into three groups: Control, AlCl3, and AlCl3 + hWJ-MSC. AlCl3 (300 mg/kg/day) was administered orally for 5 days. hWJ-MSCs (1x106 cells) were injected intraperitoneally on day 11. Brain tissue RNA was isolated using TRIzol®, and cDNA synthesis was conducted. Gene expression was analyzed by real-time PCR;\u0000Result: The results of this study showed that the average of IL-1β levels in Negative Control, Positive Control and Treatment were 0.536 ± 0.342, 0.804 ± 0.801, 0.694± 0.303;\u0000Conclusion: Our study indicates that human Wharton's Jelly Mesenchymal Stem Cells (hWJ-MSCs) can reduce IL-1β levels in an Alzheimer's disease model, suggesting their potential to alleviate inflammation. Although the decrease was not statistically significant, these findings open new avenues for exploring hWJ-MSCs as a promising therapeutic option for Alzheimer's disease.\u0000\u0000Keywords: Alzheimer, hWJ-MSC, IL-1β, AlCl3","PeriodicalId":504363,"journal":{"name":"International Journal of Research and Review","volume":"47 15","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141654470","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"High Preoperative Canal Compromise as Risk Factor for Worse Neurological Outcome in Patients with Thoracolumbar Burst Fracture After Spinal Decompression and Stabilization Surgery","authors":"Sri Mahadhana, I. W. Suryanto Dusak, I. Suyasa","doi":"10.52403/ijrr.20240714","DOIUrl":"https://doi.org/10.52403/ijrr.20240714","url":null,"abstract":"Introduction: Canal compromise (CC) has been associated with neurological outcomes in thoracolumbar burst fractures, with some suggestions indicating a direct correlation with a relatively worse prognosis even after surgical intervention. This study attempted to reveal the association between the preoperative CC in thoracolumbar burst fracture undergoing posterior spinal decompression – stabilization – fusion, with postoperative neurological outcome.\u0000Methods: This study adopts a retrospective design, utilizing the medical and radiological records of total of 50 patients (41 males and nine females), with an average age of 42.4 ± 13.57 years. It divided into a case group (comprising 25 patients without neurological improvement) and a control group (consisting of 25 patients with neurological improvement). Consecutive sampling was applied to individuals meeting the predefined inclusion and exclusion criteria. Canal compromise (CC) and the initial neurological function of all participants were assessed in the preoperative period, with a subsequent evaluation of the final neurological function conducted at a minimum of six months postoperatively. Statistical analysis involved descriptive analysis and the Chi-Square test, with the cut-off point determined through Receiver Operating Characteristic (ROC) analysis.\u0000Results: The Receiver Operating Characteristic (ROC) analysis identified 40% as the cut-off point distinguishing between low and high canal compromise (CC). Univariate Chi-Square test analysis revealed a statistically significant difference in CC as a risk factor for postoperative neurological deficit. CC exceeding 40% is significantly associated with a relatively worse postoperative neurological outcome (p < 0.001; odds ratio [OR] 21).\u0000Conclusion: A high preoperative canal compromise (CC) emerges as a direct risk factor for the absence of neurological improvement in patients with thoracolumbar burst fractures, indicating that higher CC is significantly associated with a relatively poorer prognosis.\u0000\u0000Keywords: thoracolumbar burst fracture, canal compromise, neurological deficit","PeriodicalId":504363,"journal":{"name":"International Journal of Research and Review","volume":"63 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141652450","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effectiveness of Platelet Rich Plasma Injection in Comparison with Dextrose Prolotherapy on Improving Pain and Function in Osteoarthritis of Knee: A Randomized Controlled Trial","authors":"Sagolsem Adarsh Singh, Akoijam Joy Singh, Yumnam Ningthemba Singh","doi":"10.52403/ijrr.20240713","DOIUrl":"https://doi.org/10.52403/ijrr.20240713","url":null,"abstract":"Background: Osteoarthritis is a common and disabling condition that represents a substantial and increasing health burden with notable implications for the individuals affected, health-care systems, and wider socioeconomic costs. Despite significant advances in science and medicine, there is no cure for osteoarthritis. Numerous treatment options have been used for management of osteoarthritis including pharmacological and invasive techniques. Regenerative therapy like Platelet rich plasma and Prolotherapy are being extensively studied due to their ability to regenerate and repair damaged tissues.\u0000Objectives: To evaluate the effectiveness of platelet rich plasma injection in comparison with dextrose prolotherapy on improving pain and function in patients with osteoarthritis of the knee.\u0000Study Design: Randomized controlled trial\u0000Methods: A single blind randomized controlled clinical trial was carried out in the Department of Sports Medicine, Regional Institute of Medical Sciences, Imphal between September 2022 to February 2024. A total of 92 patients were recruited and block of four randomization was done for allotment of the study participants. The outcome measures were visual analog scale (VAS) and Western Ontario Mac Master Osteoarthritis Index (WOMAC) score. For descriptive statistics mean, standard deviation and frequency were used. Student’s t-test and Chi square tests were used for analysis of different variables. A p-value <0.05 was taken as significant.\u0000Results: The 2 groups were homogeneous in terms of baseline characteristics like age, sex, side of affection and duration of symptoms (Table 1). The outcome variables of VAS and WOMAC score at baseline were not significant (Table 2). The mean age of the participants was 63.18 ± 5.15 in years. The mean duration of symptoms was 10.16 ± 1.22 in months. Between the groups comparison at the end of 4 weeks showed that there was no statistically significant reduction in the mean difference of outcome measures from baseline. However, at the end of 12 weeks and 24 weeks (p<0.05), there was statistically significant reduction in mean difference of outcome measures from baseline in both the groups but this was more in the Platelet rich plasma group.\u0000Conclusion: Platelet rich plasma injection was more effective in comparison to dextrose prolotherapy injections on improving pain and function in patients with osteoarthritis of knee at 24 weeks.\u0000\u0000Keywords: Osteoarthritis; Knee; platelet-rich plasma; prolotherapy;","PeriodicalId":504363,"journal":{"name":"International Journal of Research and Review","volume":"15 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141654127","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}