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Characterization of Poly-organic Fertilizer from Leucaena leucocephala (Lam) de Wit (IPIL-IPIL) and Its Application in a Home-grown Solanum lycopersicum L. (Tomato) Set-up 从 Leucaena leucocephala (Lam) de Wit(IPIL-IPIL)中提取的多有机肥料的特性及其在家庭种植番茄中的应用
Asian Journal of Chemical Sciences Pub Date : 2024-07-13 DOI: 10.9734/ajocs/2024/v14i3313
Desiree Nicole Maceriano, Judy Ann H. Brensis, Flyndon Mark S. Dagalea
{"title":"Characterization of Poly-organic Fertilizer from Leucaena leucocephala (Lam) de Wit (IPIL-IPIL) and Its Application in a Home-grown Solanum lycopersicum L. (Tomato) Set-up","authors":"Desiree Nicole Maceriano, Judy Ann H. Brensis, Flyndon Mark S. Dagalea","doi":"10.9734/ajocs/2024/v14i3313","DOIUrl":"https://doi.org/10.9734/ajocs/2024/v14i3313","url":null,"abstract":"Fertilizers serve as essential supplements in modern agriculture, playing an essential role in supplementing soil fertility and promoting healthy plant growth. The Northern Samar Provincial Agriculture Office reported a 27.94% 5-year percentage change of tomato harvest in the entire province, and this increase in harvest throughout the years were observed with the use of organic fertilizers. This study developed an organic fertilizer from Leucaena leucocephala (Lam) de Wit (Ipil-ipil) with Polyvinyl Alcohol to be used in a home-grown Solanum lycopersicum L. (Tomato). Functional groups were investigated using FTIR. The soil physicochemical properties were analyzed to determine the soil’s texture, pH, and macronutrient content. Tomato plant growth parameters such as plant weight and number of fruits were also identified. Test of significant relationship among the fertilizer treatments and the parameters were assessed with the use of Analysis of Variance. The functional group present in the Ipil-ipil leaf powder were hydroxyl, alkyl, amino, and carbonyl groups. The results revealed that the soil has silty clay texture, has a weakly acidic pH level, and contains varying macronutrients level. Tomato plants with Ipil-ipil organic fertilizer and PVA-containing Ipil-ipil fertilizer were the same in terms of the weight in kilograms. In terms of number of fruits, Ipil-ipil fertilizer with PVA has the greatest number of fruits among the other different fertilizer treatments. Use of the other parts of Ipil-ipil plant for fertilizer, implementing the fertilizer for different soil types and climatic conditions for plant, and exploring various application methods and dosage levels of fertilizers were recommended.","PeriodicalId":503889,"journal":{"name":"Asian Journal of Chemical Sciences","volume":"40 22","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141650925","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sequential Fractionation of Heavy Metals from Flooded and Non-Flooded Soils in Obunagha Community, Bayelsa State, Nigeria 尼日利亚巴耶尔萨州 Obunagha 社区淹水和非淹水土壤中重金属的顺序分馏
Asian Journal of Chemical Sciences Pub Date : 2024-07-02 DOI: 10.9734/ajocs/2024/v14i3312
Erepamowei, Y., O. C. J., F. I., Ajoko, I. T.
{"title":"Sequential Fractionation of Heavy Metals from Flooded and Non-Flooded Soils in Obunagha Community, Bayelsa State, Nigeria","authors":"Erepamowei, Y., O. C. J., F. I., Ajoko, I. T.","doi":"10.9734/ajocs/2024/v14i3312","DOIUrl":"https://doi.org/10.9734/ajocs/2024/v14i3312","url":null,"abstract":"Soil samples from flooded and non-flooded areas of different farmlands in Obunagha community, Bayelsa State were collected for this study. The aim of the study was to investigate the chemical fractionation and bioavailability of Cr, Cd, Zn, Ni, & Fe in flooded and non-flooded farmlands. The soil samples were fractionated into six chemical fractions, each containing different heavy metal concentrations and analyzed using flame atomic absorption spectrophotometer. The highest average concentration for Cadmium (Cd) is 1.50g/kg, Zinc (Zn) is 7.53g/kg, Nickel (Ni) is 10.54g/kg, Iron (Fe) is 9.52g/kg, and Chromium (Cr) is 12.62g/kg all from the flooded areas of the farmlands. Sequential extraction showed heavy metals distributed throughout all extraction steps, with the water-soluble fraction prevailing, potentially increasing the mobility and bioavailability of these metals. The %bioavailability ranged from 37.98% – 90.00%.  The results indicated also that the average concentration of the metals in flood affected farmland were more than the non-flooded areas. The results indicated that floods affect farmland metal content by altering contaminant bioavailability, causing adverse environmental effects. Also, the results of the heavy metals analyses revealed that the levels of nickel, zinc, chromium, cadmium and iron in all the farmland soil samples are above the maximum allowable concentration for heavy metals in soil set by WHO Guidelines provided. Hence, the farmland soils are not safe for agricultural activities. We therefore, recommend regular monitoring of the soils to prevent excessive build-up of these toxic heavy metals.","PeriodicalId":503889,"journal":{"name":"Asian Journal of Chemical Sciences","volume":"360 18","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141686388","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparison of Investigated Levels of Physicochemical Parameters in Qua Iboe River, Oruk Anam, Nigeria with Portable Water Standards 尼日利亚奥鲁克阿纳姆 Qua Iboe 河理化参数调查水平与便携式水标准的比较
Asian Journal of Chemical Sciences Pub Date : 2024-06-02 DOI: 10.9734/ajocs/2024/v14i3309
Nsima Amos Akpan, Rosemary Boniface Udombeh, Ekaete Jacob Abai
{"title":"Comparison of Investigated Levels of Physicochemical Parameters in Qua Iboe River, Oruk Anam, Nigeria with Portable Water Standards","authors":"Nsima Amos Akpan, Rosemary Boniface Udombeh, Ekaete Jacob Abai","doi":"10.9734/ajocs/2024/v14i3309","DOIUrl":"https://doi.org/10.9734/ajocs/2024/v14i3309","url":null,"abstract":"This research was carried out for comparision of status of physicochemical parameters in Qua Iboe River, Oruk Anam, Nigeria with portable water standards. Water samples were collected from five sampling locations in the study area for analysis of the physicochemical parameters in wet and dry seasons. Physicochemical parameters were determined using standard methods. Data generated were subjected to statistical analysis with Statistical Package for Social Science. The levels of some of the parameters were higher in dry season than wet season. Higher levels of some of the parameters were obtained in downstream than upstream and was ascribed to variation in levels of anthropogenic activities across the sampling locations. By extension, this indicated a likelihood of future escalation in levels of the physicochemical parameters in the river beyond permissiable limits given by World Health Organisation and other regulatory bodies in areas of higher levels of anthropogenic activities if the trend is not curbed. Comparatively, the levels of all the physicochemical parameters in the river water in both seasons were all within permissible limits for portable water standards set by World Health Organisation among other regulatory bodies. This implies that the river water quality supports life of aquatic organisms and also suitable for some domestic uses.  Principal component analysis of some of the physicochemical parameters revealed positive correlation coefficients (loadings) with one another. Hence for sustainability of the river water quality by government, regulation of anthropogenic activities in the study area is strongly advocated.","PeriodicalId":503889,"journal":{"name":"Asian Journal of Chemical Sciences","volume":"42 16","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141273937","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparative Phytochemical, In-vitro Anti-Hyperglycemic Activities of Napoleona vogelii Hook & Planch Stem Bark and Cassia occidentalis L. Root Extracts Napoleona vogelii Hook & Planch 茎皮和 Cassia occidentalis L. 根提取物的植物化学和体外抗高血糖活性比较
Asian Journal of Chemical Sciences Pub Date : 2024-04-14 DOI: 10.9734/ajocs/2024/v14i3304
Anarado Ce, Anarado Cjo, Okonkwo Na, Obumselu Of, Anyanna, Kj, Ikeh Oa, Igbokwe Ia
{"title":"Comparative Phytochemical, In-vitro Anti-Hyperglycemic Activities of Napoleona vogelii Hook & Planch Stem Bark and Cassia occidentalis L. Root Extracts","authors":"Anarado Ce, Anarado Cjo, Okonkwo Na, Obumselu Of, Anyanna, Kj, Ikeh Oa, Igbokwe Ia","doi":"10.9734/ajocs/2024/v14i3304","DOIUrl":"https://doi.org/10.9734/ajocs/2024/v14i3304","url":null,"abstract":"This work investigated the comparative phytochemical, proximate and anti-hyperglycemic activities of stem bark of Napoleonaea vogelii and root of Cassia occidentals extracts. Stem bark and N. vogelii root of C. occidentalis were cold extracted with methanol, ethyl acetate, and n-hexane. The extracts were subjected to proximate, phytochemical analyses and anti-hyperglycemic assays. The result of proximate analysis revealed that stem bark of N. vogelii was made up of 40.28 ± 0.49 % crude fibre, 37.05 ± 0.05 % carbohydrates, 7.45 ± 0.45 % protein and more than 6.00 % oil content. whereas 22.33±0.08 % crude fibre, 44.70± 0.93 % carbohydrates, 10.72± 0.05 % protein and 11.00± 0.00 % oil contents in roots of C. occidentalis. Alkaloids and terpenoids were present in all the extracts of N. vogelii and C. occidentalis. Flavonoids were also found in all extracts of N. vogelii, whereas tannins and glycosides were also found in all extracts of C. occidentalis. In vitro antidiabetic screening of the methanol extracts indicated that both plants showed a good concentration-dependent percentage glucose uptake. In all concentrations, extracts of C. occidentalis exhibited better glucose uptake than N. vogelii extracts. comparable to the activity of the standard drug- metronidazole (68.44±0.00 %), From 0.10 – 0.50 mg/mL, the methanol extracts of both plants also showed a dose-dependent α-amylase inhibitory effect.  But the inhibition decreased as the concentration was increased to 1.00 mg/mL. At 0.50 mg/mL, C. occidentalis and N. vogelii showed percentage inhibitory effect of 50.02±0.035 and35.61±0.01. Both plants’ extracts showed good anti-hyperglycemic activity, which may be due to the presence of alkaloids, terpenoids, saponins and tannins in the extracts, validating the folkloric use of both plants in the treatment of diabetes, and thus are good anti-diabetic agents.","PeriodicalId":503889,"journal":{"name":"Asian Journal of Chemical Sciences","volume":"219 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140704639","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Synthesis and Characterization of Activated Carbon from Mahogany Fruit Shell (Khaya senegalensis) Impregnated with TiO2 Used in the Adsorption of Cadmium and Arsenic 红木果壳(Khaya senegalensis)浸渍 TiO2 的活性炭的合成及其在镉和砷吸附中的应用表征
Asian Journal of Chemical Sciences Pub Date : 2024-04-08 DOI: 10.9734/ajocs/2024/v14i2303
Wilson Lamayi Danbature, N. Y. Pindiga, Auwal Musa Ibrahim
{"title":"Synthesis and Characterization of Activated Carbon from Mahogany Fruit Shell (Khaya senegalensis) Impregnated with TiO2 Used in the Adsorption of Cadmium and Arsenic","authors":"Wilson Lamayi Danbature, N. Y. Pindiga, Auwal Musa Ibrahim","doi":"10.9734/ajocs/2024/v14i2303","DOIUrl":"https://doi.org/10.9734/ajocs/2024/v14i2303","url":null,"abstract":"In this Study, low-cost activated carbon impregnated with TiO2 (Ac/ TiO2) was prepared from mahogany fruit shell (Khaya senegalensis) by chemical activation using phosphoric acid, H3PO4. The resulting product was evaluated for the removal of Arsenic and Cadmium ions from aqueous solutions. The prepared activated carbon was characterized using SEM, FTIR and XRD. Operational parameters such as initial concentration, adsorbent dose, contact time, effects of pH and temperature were studied in a batch system. It was found that the percentage removal for arsenic and cadmium were around 98 and 97% respectively. Equilibrium of the adsorption processes were obtained by testing the adsorption data using two different isotherm models: Langmuir and Freundlich. The adsorption of arsenic fitted well with Freundlich with R2 value of 0.9106. The kinetic of adsorption process was tested through pseudo first order and pseudo second order models. The Pseudo Second Order Kinetic Model provides the best correlation for the experimental data of both the two metals studied. Thermodynamics parameters, such as ΔGo, ΔHo and ΔS0 were also calculated. This result shows that the process of adsorption for arsenic was spontaneous and exothermic, while that of cadmium was spontaneous and endothermic.","PeriodicalId":503889,"journal":{"name":"Asian Journal of Chemical Sciences","volume":"10 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140730143","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Quality Assurance and In-vitro Bioequivalence Analysis of Amlodipine Besylate Tablets 苯磺酸氨氯地平片的质量保证和体外生物等效性分析
Asian Journal of Chemical Sciences Pub Date : 2024-04-04 DOI: 10.9734/ajocs/2024/v14i2302
Edebi N Vaikosen, Samuel J. Bunu, Samson K. Santus, O. D. Balogun, Dorcas Nyalas-Omeire
{"title":"Quality Assurance and In-vitro Bioequivalence Analysis of Amlodipine Besylate Tablets","authors":"Edebi N Vaikosen, Samuel J. Bunu, Samson K. Santus, O. D. Balogun, Dorcas Nyalas-Omeire","doi":"10.9734/ajocs/2024/v14i2302","DOIUrl":"https://doi.org/10.9734/ajocs/2024/v14i2302","url":null,"abstract":"The proliferation of generic brands in the local pharmaceutical market makes it increasingly difficult for health professionals and patients to choose the optimal drug. The study aimed to assess the physicochemical parameters of generic amlodipine besylate tablets utilizing in-vitro testing to eliminate health hazards and maximize safety. Five brands (A, B, C, D, and E) of amlodipine besylate tablets (5 mg) were examined for six in-vitro tests; thickness, hardness, friability, uniformity of weight, disintegration, dissolution, and thin layer chromatography (TLC). The dissolution test revealed that Brand D had the highest percentage of drug release at 5 minutes (106.2%), followed by Brand E (103.2%), A (70.7%), B (64.4%), and C (61.0%), respectively. The spectrophotometric measurement was carried out at 240 nm. All five brands satisfied the British Pharmacopeia standard for uncoated tablet weight homogeneity (less than 5% variance) and disintegration within 15 minutes. Brand A has the longest disintegration time (4.37 minutes), whereas Brand B has the shortest (3.05). Brand E had the maximum hardness of 8.7 kg/cm², and Brand B had the lowest hardness of 3 kg/cm². All five brands had a friability percentage of less than 1%, with bread B having the highest (0.91%) and brand E, lowest (0.10%), all tablets crumbled after 15 minutes. All brands passed the quality assessment test. Conclusion: The Quality Assurance and in-vitro bioequivalence assay methods used in this study are dependable, simple, and inexpensive, and they can be used consistently to evaluate amlodipine tablets and other solid-dosage pharmaceutical products.","PeriodicalId":503889,"journal":{"name":"Asian Journal of Chemical Sciences","volume":"11 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140743546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Characterization of a Bioplastic Product from the Ulva reticulata (Ribbon Sea Lettuce) Extract 从带状海莴苣(Ulva reticulata)提取物中提取的生物塑料产品的特性分析
Asian Journal of Chemical Sciences Pub Date : 2024-03-30 DOI: 10.9734/ajocs/2024/v14i2301
Maria Erica R. Bordeos, Flyndon Mark S. Dagalea, M. G. Vicencio
{"title":"Characterization of a Bioplastic Product from the Ulva reticulata (Ribbon Sea Lettuce) Extract","authors":"Maria Erica R. Bordeos, Flyndon Mark S. Dagalea, M. G. Vicencio","doi":"10.9734/ajocs/2024/v14i2301","DOIUrl":"https://doi.org/10.9734/ajocs/2024/v14i2301","url":null,"abstract":"Humans have a strong reliance in using petroleum-based plastics which take several decades to degrade and cause a lot of environmental problems such as pollution. This study intended to develop bioplastics from Ulva reticulata (Ribbon sea lettuce) and to determine the bioplastic’s physicochemical properties. The sample was collected in Allen, Northern Samar, Philippines, water samples were also collected. After the extraction, development of bioplastic from the sample extract commenced. The developed bioplastic underwent several test to check the stability of the product – its includes physicochemical analysis, tensile strength, thickness, moisture content, and soil degradation test. The Ribbon sea lettuce bioplastic solution was slightly acidic. The seaweed bioplastic have an average thickness of 0.30mm. The Ribbon sea lettuce bioplastic sample was both insoluble in the three solvents. The sample bioplastic can handle an average load of 55.12g. An average moisture content of 51.534% have been observed in the three trial of the seaweed bioplastic sample. The seaweed bioplastic sample naturally degraded during the soil biodegradation test and have lost an average weight percentage of 82.05% after 21 days of being buried in soil. The results showed that the seaweed bioplastic has a potential as an alternative to the non-biodegradable plastic and can be used in agricultural, industrial and economic purposes.","PeriodicalId":503889,"journal":{"name":"Asian Journal of Chemical Sciences","volume":"39 17","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140362308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Synthesis of TiO(_2) Impregnated Ribes nigrum Stem Nanoactivated Carbon and their Application to Remove Heavy Metals TiO (_2)浸渍黑葡萄茎纳米活性炭的合成及其在去除重金属中的应用
Asian Journal of Chemical Sciences Pub Date : 2024-03-26 DOI: 10.9734/ajocs/2024/v14i2300
B. Magaji, N. Y. Pindiga, Ibrahim Mohammed Bida
{"title":"Synthesis of TiO(_2) Impregnated Ribes nigrum Stem Nanoactivated Carbon and their Application to Remove Heavy Metals","authors":"B. Magaji, N. Y. Pindiga, Ibrahim Mohammed Bida","doi":"10.9734/ajocs/2024/v14i2300","DOIUrl":"https://doi.org/10.9734/ajocs/2024/v14i2300","url":null,"abstract":"Nanoactivated carbons from Ribes nigrum (black currant) stem were prepared using two-step procedure with excellent yield and were characterized using different spectroscopic techniques. The FTIR spectroscopy revealed O-H, C=C, C=N, and C-O stretching. XRD analysis revealed the particle sizes as 29.57 nm for stem activated carbon (SAC) and 26.55 nm for stem activated carbon impregnated with titanium (SAT) while, the morphology of the SAC and SAT were revealed by SEM to be spherical, granular and porous. The prepared nanoactivated materials were used for removal of Pb2+ and Cd2+ from aqueous solution. The influences of initial metal ion concentration, agitation time, adsorbent dose, temperature and pH were studied in batch experiments at room temperature. The adsorption equilibriums were rapid at 60 min of agitation for Pb2+ and Cd2+ on SAT with appreciable %removal. The adsorption data for Pb2+ and Cd2+ on SAT fitted well into Freundlich isotherm than Langmuir given correlation coefficient (R2) very close to unity and appreciable maximum adsorption capacity KF > 1.00. The fitting into Freundlich indicates multilayer coverage on the adsorbents. The kinetic studies showed good correlation coefficient for a pseudo-second order kinetic model for the SAT. The enthalpies of the adsorption process are: +12.754 and +18.377 KJ mol-1 for Pb2+ and Cd2+ on SAT respectively. The entropies of the adsorption process were also evaluated and have been found to be +41.805 and +12.151 KJ mol-1 for Pb2+ and Cd2+ on SAT. The results showed that SAT has the potential to be applied as alternative low-cost nanoadsorbents in the remediation of metal contamination in water.","PeriodicalId":503889,"journal":{"name":"Asian Journal of Chemical Sciences","volume":"122 48","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140378639","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
African Breadfruit Seed Oil as Lipid Phase of Self-Emulsifying Drug Delivery System for Improved Gastrointestinal Fluid Solubility of Ibuprofen: Design and Evaluation 非洲面包树籽油作为自乳化给药系统的脂相,用于改善布洛芬的胃肠液溶解度:设计与评估
Asian Journal of Chemical Sciences Pub Date : 2024-03-22 DOI: 10.9734/ajocs/2024/v14i2299
Romanus C. Omeh, A. M. Momoh, F. K. Asogwa, C. O. Ugwu, G. W. Ugodi, T. Ujam, K. E. Oluigbo, Njideka Ani, Ndidiamaka H. Okorie, Paul E. Ugwu
{"title":"African Breadfruit Seed Oil as Lipid Phase of Self-Emulsifying Drug Delivery System for Improved Gastrointestinal Fluid Solubility of Ibuprofen: Design and Evaluation","authors":"Romanus C. Omeh, A. M. Momoh, F. K. Asogwa, C. O. Ugwu, G. W. Ugodi, T. Ujam, K. E. Oluigbo, Njideka Ani, Ndidiamaka H. Okorie, Paul E. Ugwu","doi":"10.9734/ajocs/2024/v14i2299","DOIUrl":"https://doi.org/10.9734/ajocs/2024/v14i2299","url":null,"abstract":"Introduction: Rain forest vegetations all over the world produce large quantity of economically important seed oils which, in most developing countries are utilized only as food condiments but hardly employed in pharmaceutical formulations. \u0000Objectives: The purpose of this work was to formulate ibuprofen-loaded self-emulsifying drug delivery system for the enhancement of the gastrointestinal fluid solubility of this poorly water soluble drug. \u0000Methods: The breadfruit seed oil was extracted by the soxhlet extraction technique and characterized for various physicochemical properties including acid, iodine, peroxide, saponification values and organoleptic properties.  The super saturation solubility process, water titration studies and pseudo ternary phase diagrams were used to select and quantify the components of the emulsion systems. The liquid self-emulsifying drug delivery systems were converted to solid forms by adsorption onto a blend of miceocrystalline cellulose and Aerosil-200 powders. The resulting wet mass was dried and processed for encapsulation. \u0000Results: The percentage yield of the oil from the extraction process was 20.68 % while the acid, iodine, and saponification values were, 4.12 ± 1.24, 21.91 ± 0.88, and 302.45 ± 1.22 respectively. The ibuprofen exhibited higher solubility in the hydrolysed oil than in the crude form. Fourier transform infrared analysis did not reveal existence of component incompatibility. The optimized liquid and solid emulsions exhibited standard characteristics that were compatible to previous literature reports. The formulations also exhibited superior drug release properties over two control samples. \u0000Conclusion: It was concluded that Breadfruit seed oil has the potential to function as the lipid component of ibuprofen-loaded self-emulsifying drug delivery system formulated to enhance the aqueous solubility of the drug.","PeriodicalId":503889,"journal":{"name":"Asian Journal of Chemical Sciences","volume":" 10","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140217185","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Wastewater Phytopurification Monitoring with Congolese Planted Filters, Republic of Congo 刚果共和国利用刚果种植过滤器进行废水植物净化监测
Asian Journal of Chemical Sciences Pub Date : 2024-03-18 DOI: 10.9734/ajocs/2024/v14i2297
G. D. Mouko, K. Mbemba, A. B. M. Mabika, J. Ouamba
{"title":"Wastewater Phytopurification Monitoring with Congolese Planted Filters, Republic of Congo","authors":"G. D. Mouko, K. Mbemba, A. B. M. Mabika, J. Ouamba","doi":"10.9734/ajocs/2024/v14i2297","DOIUrl":"https://doi.org/10.9734/ajocs/2024/v14i2297","url":null,"abstract":"The present study aimed to evaluate the purifying power of two Congolese plant filters or emerging macrophytes EP-F (Echinochloa pyramidalis (Lam) Hutch) and CA-F (Cyperus alternifolius L.) on wastewater coming from the Total market, the largest national market of Brazzaville in Congo. To do this, we set up an experimental device composed of gravel, fine sand and two plants. These plants were cultivated in an experimental pilot consisting of 8 tanks of 42,000 cm3 of wastewater at treat each one, in addition to 2 tanks used as controls. The purifying performance study of the system after 90 days of treatment showed a significant reduction in physical, organic and mineral pollution. Using the planted filter EP-F (Echinochloa pyramidalis (Lam)Hutch), we obtain reduction rates of almost 100% for turbidity and for suspended matter (SM), 75.42% for COD, 76.5% for NH4+ ions, 99.5% for NO3- ions and 99.73% for PO43- ions. In the case of the CA-F (Cyperus alternifolius L) planted filter, we obtain reduction rates of almost 100% for turbidity and SM, 80.94% for COD, 93% for ions. NH4+, 89.11% for NO3- ions and 98.93% for PO43- ions. Furthermore, we also noted an increase in organic and mineral pollutants concentrations in the two plants compared to the raw plants before wastewater passage. This study showed that Echinochloa pyramidalis (Lam) Hutch and Cyperus alternifolius L. are effective macrophyte filters to eliminate physical, organic and mineral pollution.","PeriodicalId":503889,"journal":{"name":"Asian Journal of Chemical Sciences","volume":"4 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140234823","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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