Annals of Medicine & Surgery最新文献

{"title":"Impacts of COVID-19 on hemostasis: coagulation abnormalities and management perspectives","authors":"E. Obeagu, Muhammad Tukur, Kingsley Akaba","doi":"10.1097/ms9.0000000000002237","DOIUrl":"https://doi.org/10.1097/ms9.0000000000002237","url":null,"abstract":"The coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has transcended its initial characterization as a respiratory illness, revealing substantial implications for hemostasis and coagulation pathways. COVID-19-associated coagulopathies have emerged as critical determinants of disease severity and prognosis, presenting a multifaceted challenge in clinical management. This paper aims to elucidate the intricate interplay between COVID-19 and hemostasis, delving into the underlying mechanisms of coagulation abnormalities, exploring the spectrum of thrombotic complications, and discussing evolving management strategies. Therapeutic interventions and anticoagulation strategies tailored for managing COVID-19-related coagulopathies form a significant focus, encompassing prophylactic and therapeutic approaches, heparin-based therapies, and individualized treatment paradigms. This paper underscores the imperative for ongoing research endeavors to refine diagnostic modalities, identify novel therapeutic targets, and ascertain long-term sequelae of COVID-19-induced coagulation abnormalities. Ultimately, a comprehensive understanding of the intricate relationship between COVID-19 and hemostasis is pivotal in devising effective management strategies to mitigate thrombotic risks, improve clinical outcomes, and pave the way for tailored interventions in affected individuals.","PeriodicalId":503882,"journal":{"name":"Annals of Medicine & Surgery","volume":"361 17","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141686355","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Breaking barriers: addressing inequities in Alzheimer’s disease diagnosis and treatment in Africa","authors":"Olivier Uwishema, Bezawit Kassahun Bekele, Abubakar Nazir, Erick Filbert Luta, Elaf Abdulnaser Al-Saab, Irakiza Jacques Desire, Chukwuma Franklin ozioma, Magda Wojtara","doi":"10.1097/ms9.0000000000002344","DOIUrl":"https://doi.org/10.1097/ms9.0000000000002344","url":null,"abstract":"\u0000 \u0000 Alzheimer’s disease (AD) represents a substantial and escalating public health threat across Africa.Alzheimer’s disease leads to substantial cognitive impairment and memory loss, placing a heavy burden on both the affected individuals and their families, friends, and caregivers. It affects 2. 67 million people in Africa of which the majority live in sub-Saharan Africa. The prevalence of this disease is expected to rise drastically to approximately 150 million individuals worldwide by 2050, as estimated by the World Health Organization.\u0000 \u0000 \u0000 \u0000 This paper offers an integrative profile of Alzheimer’s disease in Africa spanning known genetic and modifiable risks, discuss the existing challenges in diagnosis and treatment, projections on prevalence and disability-adjusted life year burden through 2050, and priority policy responses needed to rebalance the equation.\u0000 \u0000 \u0000 \u0000 This paper examines available literature to summarize current knowledge on risk factors, diagnosis, treatments, and burden of Alzheimer’s disease in Africa. Gathering epidemiological assessments, clinical guidelines and commentary related to Alzheimer’s disease in Africa.\u0000 \u0000 \u0000 \u0000 The data reveals concerning realities regarding Alzheimer’s disease diagnosis and care in Africa. Diagnostic infrastructure shortcomings, resource limitations and knowledge gaps emerge as recurring barriers. PET scans, CSF assays and other mainstay detection modalities common in developed countries show restricted availability\u0000 \u0000 \u0000 \u0000 Addressing Africa’s Alzheimer’s disease crisis demands a multi-pronged strategy to uplift diagnostic capacities, treatment availability, specialist training, public awareness and coordinated policymaking. Prioritizing biomarkers and imaging to confirm early neurodegeneration is foundational, alongside drug access expansion.\u0000","PeriodicalId":503882,"journal":{"name":"Annals of Medicine & Surgery","volume":"134 33","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141714178","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Minimally invasive spleen preserving surgery to treat primary splenic hydatidosis: short and long term outcomes: a cohort study","authors":"Anas Aljaiuossi, Saleh A. Ba-shammakh, Mohammad Bani Hani, Musab S. Al-A’athal, Yazeed M. Elsobuh, Hashim Abu Sarhan, Raed Mahmoud Ennab, M. Al-Zubi, Mohammad J. Alhwari, Laith G. Al Omari, Feras M. Mohammad, Mohamed S. AL lami, Hammam B. Zeitoon, Saad A. Alomari, Salman M. Ababneh","doi":"10.1097/ms9.0000000000002320","DOIUrl":"https://doi.org/10.1097/ms9.0000000000002320","url":null,"abstract":"\u0000 \u0000 Primary splenic hydatidosis, a rare manifestation of Echinococcus granulosus infection, presents unique diagnostic and therapeutic challenges. This study compares spleen-preserving surgeries with total splenectomy for treating primary splenic hydatid cysts, focusing on short- and long-term outcomes in the Jordanian context, a region particularly affected by this condition.\u0000 \u0000 \u0000 \u0000 This retrospective analysis was conducted on 18 patients diagnosed with primary splenic hydatid cysts at two Jordanian hospitals from January 2015 to June 2021. Selection criteria included confirmed diagnosis and complete medical records. Surgical approaches, including laparoscopic partial splenectomy, cystectomy, and cyst deroofing, supplemented by albendazole therapy, were compared based on patient demographics, symptoms, surgical details, complications, and recurrence rates.\u0000 \u0000 \u0000 \u0000 The study group was composed of (n=7, 38.9%) male and (n=11, 61.1%) female patients, with an average age of 33.7 years. Most presented with left upper quadrant pain. Postoperative complications occurred in 22% of patients, with an 11% recurrence rate during follow-up. No significant statistical difference in recurrence rates was observed between spleen-preserving surgeries and total splenectomy. These findings highlight the efficacy of less invasive, spleen-preserving techniques in managing primary splenic hydatidosis, showing comparable outcomes to total splenectomy with minimal impact on recurrence rates.\u0000 \u0000 \u0000 \u0000 Spleen-preserving surgery offers a viable alternative to total splenectomy in treating primary splenic hydatid cysts. This approach maintains immune functionality and reduces septic risks, especially in pediatric patients. The study underscores the importance of individualized treatment approaches and suggests further research with larger cohorts for more comprehensive insights into managing this rare condition. The limitations of this study include its small sample size and retrospective nature.\u0000","PeriodicalId":503882,"journal":{"name":"Annals of Medicine & Surgery","volume":"113 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141714546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A case report on posterior reversible encephalopathy syndrome (PRES) in an elderly female","authors":"Sonu Adhikari, Neeyal Shrestha, Dinuj Shrestha, Rupesh Raut, Prajeet Ray, Prakash Bista, Ayam Bhattarai","doi":"10.1097/ms9.0000000000002343","DOIUrl":"https://doi.org/10.1097/ms9.0000000000002343","url":null,"abstract":"\u0000 \u0000 Posterior Reversible Encephalopathy Syndrome (PRES) is a medical condition characterized by symptoms such as headache, altered consciousness, visual abnormalities, seizures, and associated radiological vasogenic edema. The condition, as its name suggests, is generally reversible. PRES typically affects individuals around the age of 45 and is rarely seen in the elderly population.\u0000 \u0000 \u0000 \u0000 In this report, we present the case of an 83-year-old woman who presented to the emergency department with a history of seizures and visual disturbances. Upon examination, her Glasgow Coma Scale (GCS) was 14, and she had a bilateral round, reactive regular pupils. A plain CT head was performed, which revealed multiple hemorrhagic areas in the occipital region associated with vasogenic edema. MRI was done which was suggestive of Posterior Reversible Encephalopathy Syndrome (PRES). The individual underwent conservative management in our institute and gradually recovered.\u0000 \u0000 \u0000 \u0000 Posterior Reversible Encephalopathy Syndrome (PRES) typically presents in middle-aged individuals, with infrequent occurrences in the elderly population. Early radiological and clinical assessments are crucial for the prompt diagnosis of this condition. Additionally, it is essential to identify predisposing factors such as hypertension, eclampsia, electrolyte imbalances, renal failure, autoimmune diseases, and the use of cytotoxic drugs for optimum management of the patient.\u0000 \u0000 \u0000 \u0000 Posterior reversible encephalopathy syndrome (PRES) is generally reversible, as its name implies. Maintaining a high level of suspicion based on radiological and clinical correlations, coupled with the effective management of underlying conditions, can contribute to its potential reversibility.\u0000","PeriodicalId":503882,"journal":{"name":"Annals of Medicine & Surgery","volume":"39 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141713131","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Treatment of recurrent uveitis and ankylosing spondylitis with golimumab: a case report, Letter to Editor","authors":"Maysoun Kudsi, Tasneem Drie, Sumaya Dumirieh","doi":"10.1097/ms9.0000000000002342","DOIUrl":"https://doi.org/10.1097/ms9.0000000000002342","url":null,"abstract":"\u0000 \u0000 Uveitis, as an extra-articular presentation, is found in 23% of patients with Ankylosing Spondylitis and is a challenging disease to treat.\u0000 \u0000 \u0000 \u0000 we presented A 32-year-old male presented to the out-hospital, complaining of recurrent anterior uveitis 8 years earlier in his left eye, and suffered from inflammatory lumber pain for 2 years. so a diagnosis of Ankylosing Spondylitis(AS) after the failure of many therapeutic strategies, 50 mg /month subcutaneous Golimumab was started with clinical remission of AS and uveitis.\u0000 \u0000 \u0000 \u0000 The American College of Rheumatology 10 recommends the use of etanercept and adalimumab in the treatment of recurrent uveitis in AS patients. Similarly, the European League Against Rheumatism11 recommended using Infliximab, Adalimumab, or Certolizumab to prevent the recurrence of uveitis recurrence. Till now, a case about treating refractory uveitis with Golimumab in AS patients was published1.\u0000 \u0000 \u0000 \u0000 Golimumab was found to be effective in the treatment of uveitis associated with spondyloarthritis refractory at least one immunosuppressive drug.\u0000","PeriodicalId":503882,"journal":{"name":"Annals of Medicine & Surgery","volume":"2 8","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141701432","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Connor-davidson resilience scale: A systematic review psychometrics properties using the COSMIN","authors":"Hamid Sharif-Nia, David Sánchez-Teruel, Erika Sivarajan Froelicher, S. Hejazi, L. Hosseini, Fatemeh Khoshnavay Fomani, Mozhgan Moshtagh, Fereshteh Mollaei, A. Goudarzian, Amir Babaei","doi":"10.1097/ms9.0000000000001968","DOIUrl":"https://doi.org/10.1097/ms9.0000000000001968","url":null,"abstract":"\u0000 \u0000 Psychometrical evaluation of persons of diverse contexts, and different populations, including general or clinical.\u0000 \u0000 \u0000 \u0000 This review study aimed to evaluate the psychometrics quality of resilience scales.\u0000 \u0000 \u0000 \u0000 International and Iranian databases were searched with MESH terms included “psychometric”, “validity”, “reliability”, “Connor-Davidson resilience scale”, “Resilience scale”, for published articles up to February 1, 2023. For each of the selected studies, risk of bias was evaluated using the COSMIN Risk of Bias Checklist. Then The COSMIN checklist was used to evaluate the entire text of the article for methodological quality.\u0000 \u0000 \u0000 \u0000 Considering the inclusion criteria, 80 documents were evaluated. According to the COSMIN’s criteria for evaluating the risk of bias, the current study findings revealed the included studies’ limitations in assessing the three versions of CD-RISC cross-cultural and content validity as well as their stability (e.g., conducting test re-test), whereas the majority of psychometric studies of CD-RISC25, and CD-RISC-2 rated as very good or adequate in terms of structural validity. In terms of quality assessment of the included studies, the current study indicated that investigating the structural validity of the CD-RISC was mainly done based on EFA (Exploratory Factor Analysis), and confirmatory factor analysis was absent.\u0000 \u0000 \u0000 \u0000 The general result indicates the acceptability of the quality of the studies. However, concerns for measurement properties such as responsiveness and criterion validity as well as the standard error of measurement have been neglected.\u0000","PeriodicalId":503882,"journal":{"name":"Annals of Medicine & Surgery","volume":"50 12","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140352516","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Chemotherapy-associated pneumoperitoneum in cancer patients: a scoping review","authors":"Renee M. Maina, Caroline A. Rader, Jeevan Kypa, Constantine Asahngwa, Hilary M. Jasmin, Nia N. Zalamea, John S. Nelson, Jonathan L. Altomar, Mary Brinson Owens, Clarisse S. Muenyi, Denis A. Foretia","doi":"10.1097/ms9.0000000000001998","DOIUrl":"https://doi.org/10.1097/ms9.0000000000001998","url":null,"abstract":"\u0000 \u0000 The presence of air in the peritoneal cavity (pneumoperitoneum) is often secondary to perforated viscus. Emergent operative intervention is typically warranted in non-cancer patients. Cancer patients present a unique challenge as they have increased risk of pneumoperitoneum due to local tumor invasion, radiation therapy and frequent endoscopic procedures. There is a paucity of literature on the management of patients undergoing chemotherapy who present with pneumoperitoneum. We conducted a scoping review to identify and synthesize preliminary evidence on the presentation, management, and outcomes of this patient population.\u0000 \u0000 \u0000 \u0000 A scoping review of cases of pneumoperitoneum in cancer patients from 1990 – 2022 was conducted using the Arksey and O’Malley five-stage approach. Inclusion criteria were a known diagnosis of cancer, chemotherapy within 6 months of presentation, and imaging confirmation of pneumoperitoneum. Our exclusion criteria were cancer diagnosis at the time of presentation, perforation secondary to local cancer invasion, and last chemotherapy session greater than 6 months prior to presentation.\u0000 \u0000 \u0000 \u0000 34 cases (8 pediatric, 26 adults) were identified. The median time from the last chemotherapy treatment to presentation with pneumoperitoneum was 14 days. 21 patients were managed operatively and 13 were managed non-operatively. The most common source of perforation was multiple sites along the bowel. 30-day mortality was 33.3% for the operative cohort and 23.1% for the nonoperative group.\u0000 \u0000 \u0000 \u0000 Pneumoperitoneum in cancer patients remains a highly morbid condition with a mortality rate of approximately 30% regardless of the treatment approach. Non-operative management should be pursued whenever possible.\u0000","PeriodicalId":503882,"journal":{"name":"Annals of Medicine & Surgery","volume":" 33","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140210336","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Antinociceptive effects of gamma-linolenic acid in the formalin test in the rats","authors":"K. Rahimi, Arman Nourishirazi, Hamidreza Delaviz, Z. Ghotbeddin","doi":"10.1097/ms9.0000000000002001","DOIUrl":"https://doi.org/10.1097/ms9.0000000000002001","url":null,"abstract":"\u0000 \u0000 Gamma-linolenic acid (GLA) is found in animals and plants that play a role in brain function and metabolism.\u0000 \u0000 \u0000 \u0000 This study aimed to investigate the analgesic effects of GLA on peripheral formalin injection.\u0000 \u0000 \u0000 \u0000 Wistar rats were randomly assigned to four groups: Sham, formalin, formalin/GLA 100 mg/kg, and formalin/GLA 150 mg/kg. The Formalin test was utilized to create a pain model. A tissue sample was prepared from the spinal cords of rats to measure oxidative stress parameters and pro-inflammatory cytokines. Furthermore, we analyzed the expression of c-Fos protein in the spinal cords.\u0000 \u0000 \u0000 \u0000 Our findings demonstrate that GLA has a reliable pain-relieving effect in the formalin test. GLA 100 increased SOD (P<0.05), GSH (P<0.001), and CAT (P<0.05), and decreased the levels of c-fos (P<0.001), IL-1β (P<0.001), TNF-α (P<0.001), and MDA (P<0.001) in the spinal cord. Also GLA 150 increased SOD (P<0.05), GSH (P<0.001), and CAT (P<0.05), and decreased the levels of c-fos (P<0.001), IL-1β (P<0.001), TNF-α (P<0.001), and MDA (P<0.001) in the spinal cord.\u0000 \u0000 \u0000 \u0000 The findings have validated the antinociceptive impact of GLA and hinted towards its immunomodulatory influence in the formalin test.\u0000","PeriodicalId":503882,"journal":{"name":"Annals of Medicine &amp; Surgery","volume":" 32","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140209919","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A successful management of candy cane syndrome post Roux-en-Y gastric bypass: a rare case report","authors":"Youssef Ahmad, Qamar Sleman, Umer Siddiqui, Sandra Cuevas, Gurkiran Gill, Fadi Souleiman","doi":"10.1097/ms9.0000000000001983","DOIUrl":"https://doi.org/10.1097/ms9.0000000000001983","url":null,"abstract":"\u0000 \u0000 Candy Cane Syndrome (CCS) is a rare condition in which the proximal gastro-jejunal attachment’s afferent blind limb is elongated. This can lead to different symptoms including nausea and vomiting, with less common described reflux and regurgitation symptoms.\u0000 \u0000 \u0000 \u0000 A 38-year-old female presented with a chronic complaint of postprandial pain, discomfort, and reflux lasting for about 2 years after a previous Roux-en-y gastric bypass (RYGB) surgery. Upper endoscopy was done and raised suspicion for CCS. The patient underwent an exploratory laparoscopy which confirmed the diagnosis. Surgical resection of the afferent limb was done, and all symptoms were completely resolved at the post-operative follow-up.\u0000 \u0000 \u0000 \u0000 CCS is considered a rare described complication that can occur after RYGB gastric bypass surgery. Diagnosing this condition includes performing upper gastrointestinal (GI) studies and endoscopy, which reveal a redundant afferent limb. Laparoscopy serves as a dual-purpose tool, confirming the diagnosis of CCS and providing a definitive curative intervention. Surgical resection has a high success rate, with evidence supporting its efficacy in relieving symptoms.\u0000 \u0000 \u0000 \u0000 As the popularity of Bariatric surgeries rises, it is crucial to consistently consider CCS, despite its rarity, as a potential complication. Although diagnosing CCS can be challenging, physicians should maintain a high index of suspicion, especially in patients presenting with upper GI symptoms following metabolic surgeries.\u0000","PeriodicalId":503882,"journal":{"name":"Annals of Medicine &amp; Surgery","volume":" 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140209932","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The relationship between serum 25-Hydroxy vitamin D status and hypertension in syrian population: retrospective cohort study","authors":"Nouha Abd AL-Hameid Bakkar, Aliaa Youssef Bakr, Ayham Alhusseini, Z. Alourfi","doi":"10.1097/ms9.0000000000001989","DOIUrl":"https://doi.org/10.1097/ms9.0000000000001989","url":null,"abstract":"\u0000 \u0000 Vitamin D is a liposoluble steroid hormone that plays a crucial role in the maintenance of bone metabolism and calcium homeostasis. Many studies on the effects of vitamin D on general health have been significantly increased, driven by new findings concerning the systemic and extraskeletal effects of this hormone. This study was performed to determine whether low levels of vitamin D were associated with hypertension in Syrian people.\u0000 \u0000 \u0000 \u0000 This retrospective cohort study consisted of 207 subjects, including 83 (40.1%) patients suffering from essential hypertension, and 124 (59.9%) patients with normal blood pressure. Aged>18 years, who was referred to endocrinology clinic from September 2022 to September 2023. The data were analysed by using SPSS (version 25). Logistic regression analyses was performed with adjustments for age, sex, and waist circumference.\u0000 \u0000 \u0000 \u0000 Hypertension rates were 73%, 20%, and 5% in 25-hydroxyvitamin D groups<12 ng/ mL, 12 to 20 ng/mL, and>=20 ng/mL, respectively. Odds ratios (95% confidence intervals) for hypertension adjusting for age, sex, and waist circumference were 178.6(30.5_1045.6), 5.13(0.9_26.5) for 25-hydroxyvitamin D levels<12 ng / mL, and 12 to 20 ng / mL, respectively, compared with the>=20 ng/mL group.\u0000 \u0000 \u0000 \u0000 This study shown high prevalence of low vitamin D levels (25OHVD˂20 ng/mL) among a sample of Syrian people (78.3%). The lowest 25OHVD group was associated with higher prevalence of hypertension, that refers to adverse association between vitamin D level and essential hypertension. Further research is needed to confirm this relationships.\u0000","PeriodicalId":503882,"journal":{"name":"Annals of Medicine &amp; Surgery","volume":" 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140209967","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}