A case report on posterior reversible encephalopathy syndrome (PRES) in an elderly female

Sonu Adhikari, Neeyal Shrestha, Dinuj Shrestha, Rupesh Raut, Prajeet Ray, Prakash Bista, Ayam Bhattarai
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Abstract

Posterior Reversible Encephalopathy Syndrome (PRES) is a medical condition characterized by symptoms such as headache, altered consciousness, visual abnormalities, seizures, and associated radiological vasogenic edema. The condition, as its name suggests, is generally reversible. PRES typically affects individuals around the age of 45 and is rarely seen in the elderly population. In this report, we present the case of an 83-year-old woman who presented to the emergency department with a history of seizures and visual disturbances. Upon examination, her Glasgow Coma Scale (GCS) was 14, and she had a bilateral round, reactive regular pupils. A plain CT head was performed, which revealed multiple hemorrhagic areas in the occipital region associated with vasogenic edema. MRI was done which was suggestive of Posterior Reversible Encephalopathy Syndrome (PRES). The individual underwent conservative management in our institute and gradually recovered. Posterior Reversible Encephalopathy Syndrome (PRES) typically presents in middle-aged individuals, with infrequent occurrences in the elderly population. Early radiological and clinical assessments are crucial for the prompt diagnosis of this condition. Additionally, it is essential to identify predisposing factors such as hypertension, eclampsia, electrolyte imbalances, renal failure, autoimmune diseases, and the use of cytotoxic drugs for optimum management of the patient. Posterior reversible encephalopathy syndrome (PRES) is generally reversible, as its name implies. Maintaining a high level of suspicion based on radiological and clinical correlations, coupled with the effective management of underlying conditions, can contribute to its potential reversibility.
一名老年女性的后可逆性脑病综合征(PRES)病例报告
后可逆性脑病综合征(PRES)是一种以头痛、意识改变、视觉异常、癫痫发作和相关放射性血管源性水肿等症状为特征的疾病。顾名思义,这种病通常是可逆的。PRES 通常影响 45 岁左右的人,很少见于老年人群。 在本报告中,我们介绍了一名 83 岁女性的病例,她因癫痫发作和视力障碍病史到急诊科就诊。经检查,她的格拉斯哥昏迷量表(GCS)为 14,双侧圆形、反应性规则瞳孔。头颅 CT 平扫显示枕部有多个出血区,并伴有血管源性水肿。核磁共振检查提示为后可逆性脑病综合征(PRES)。该患者在我院接受了保守治疗并逐渐康复。 后部可逆性脑病综合征(PRES)通常发生在中年人身上,在老年人群中并不常见。早期的放射学和临床评估对于及时诊断这种疾病至关重要。此外,还必须确定高血压、子痫、电解质失衡、肾功能衰竭、自身免疫性疾病和使用细胞毒药物等易感因素,以便对患者进行最佳治疗。 后可逆性脑病综合征(PRES)顾名思义通常是可逆的。根据放射学和临床相关性保持高度怀疑,再加上对潜在疾病的有效治疗,可有助于其潜在的可逆性。
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