{"title":"Evaluation of aetiological profiles, treatment appropriateness, and outcomes of syndromic management for reproductive tract infections in women from urban clinics.","authors":"Deepti Tandon, Sowrabha Ramachandra, Shilpa Chandrakant Kerkar, Shahina Begum, Kiran Munne, Anushree Devashish Patil, Kimaya Mali, Niranjan Mayadeo, Jyotsna Shatrughan Dwivedi, Vikrant M Bhor","doi":"10.25259/IJDVL_355_2025","DOIUrl":"10.25259/IJDVL_355_2025","url":null,"abstract":"<p><p>Background While syndromic management is widely used in low-resource settings due to its cost-effectiveness and ease of patient care, growing concerns of antimicrobial resistance (AMR) and potential overtreatment highlight the need for regular aetiological testing to monitor treatment appropriateness. Aim To evaluate and compare syndromic management for reproductive tract infection for assessing treatment strategies. Methods In a prospective study, 250 sexually active, non-pregnant women aged 18-50 years, presenting with symptoms of lower genital tract infections were recruited as part of a prospective study from urban clinics in Mumbai. Participants underwent clinical and gynaecological examination, and standard syndromic management was provided. Samples were collected prior to treatment for Nugent scoring, Candida culture, and multiplex polymerase chain reaction (PCR) to detect sexually transmitted infections (STIs). Results The mean age of participants was 32.5 ± 6.6 years, with 51.2% (n=128) belonging to the upper-lower socioeconomic class. Vaginal discharge was the most common symptom (42%, n=105). Aetiological analysis identified causative agents in 90% (n=225) of cases, while 10% (n=25) showed no identifiable aetiology. The most prevalent pathogens were Ureaplasma parvum (47.2%) and Candida species (44.4%), followed by those causing bacterial vaginosis (39.2%). Among Candida species, Candida albicans (47.1%) and Candida krusei (45.2%) were most common. In contrast, Chlamydia trachomatis (3.2%) and Mycoplasma genitalium (1.2%) were less prevalent, and Neisseria gonorrhoeae was not detected. Syndromic management led to overtreatment rates exceeding 96% for these low-prevalence pathogens, raising concerns about AMR. Limitations Since this study is bounded to urban community clinics it limits the expansion to rural scene and AMR tests were not conducted due to the fastidious nature of microbes in the study and implementation challenges in resource limiting settings. Conclusion Syndromic management remains feasible in resource-limited settings; however, its limitations in addressing low-prevalence pathogens emphasise the need for periodic aetiological testing to improve diagnostic accuracy and guide appropriate treatment.</p>","PeriodicalId":50376,"journal":{"name":"Indian Journal of Dermatology Venereology & Leprology","volume":" ","pages":"1-7"},"PeriodicalIF":3.4,"publicationDate":"2025-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144876592","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Riga-Fede disease in an infant.","authors":"Ananya Arya, Gitesh U Sawatkar, Priyanka Kowe","doi":"10.25259/IJDVL_125_2025","DOIUrl":"10.25259/IJDVL_125_2025","url":null,"abstract":"","PeriodicalId":50376,"journal":{"name":"Indian Journal of Dermatology Venereology & Leprology","volume":" ","pages":"1"},"PeriodicalIF":3.4,"publicationDate":"2025-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144876612","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Newer and emerging sexually transmitted infections: A narrative review.","authors":"Ayush Jain, Sonali Gupta, Nikhil Mehta, Somesh Gupta","doi":"10.25259/IJDVL_1843_2024","DOIUrl":"10.25259/IJDVL_1843_2024","url":null,"abstract":"<p><p>Sexually transmitted infections (STIs), including traditionally curable diseases like syphilis and gonorrhoea, have seen a recent resurgence. Concurrently, newer atypical infections presenting as STIs have emerged, driven by changes in pathogen virulence, host behaviours, and environmental factors. The spectrum of STIs is expanding due to evolving behaviours, globalisation, and pathogen adaptability. This review aims to highlight key viral, bacterial, fungal, and enteric infections that are newly identified or increasingly transmitted through sexual contact, introducing the concept of sexually transmissible infections. Though sexual transmission plays a minor role in their spread, it cannot be neglected and thus requires heightened awareness among clinicians and public health officials to ensure timely identification, management, and prevention.</p>","PeriodicalId":50376,"journal":{"name":"Indian Journal of Dermatology Venereology & Leprology","volume":" ","pages":"1-8"},"PeriodicalIF":3.4,"publicationDate":"2025-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144876605","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Shan Cao, Baoqi Yang, Shengli Chen, Hong Liu, Furen Zhang
{"title":"Successful treatment of lichen sclerosus and morphea on the hand with JAK inhibitor upadacitinib.","authors":"Shan Cao, Baoqi Yang, Shengli Chen, Hong Liu, Furen Zhang","doi":"10.25259/IJDVL_1795_2024","DOIUrl":"10.25259/IJDVL_1795_2024","url":null,"abstract":"","PeriodicalId":50376,"journal":{"name":"Indian Journal of Dermatology Venereology & Leprology","volume":" ","pages":"1-2"},"PeriodicalIF":3.4,"publicationDate":"2025-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144876516","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Agata Karny, Miłosz Nesterowicz, Julia Nowowiejska, Piotr Purpurowicz, Anna Baran, Tomasz W Kaminski, Zbigniew Purpurowicz, Iwona Flisiak
{"title":"Sexual dysfunction in female patients with acne vulgaris - A questionnaire-based survey.","authors":"Agata Karny, Miłosz Nesterowicz, Julia Nowowiejska, Piotr Purpurowicz, Anna Baran, Tomasz W Kaminski, Zbigniew Purpurowicz, Iwona Flisiak","doi":"10.25259/IJDVL_1385_2024","DOIUrl":"10.25259/IJDVL_1385_2024","url":null,"abstract":"<p><p>Background Acne vulgaris is one of the most common cutaneous chronic diseases. The disease itself or the side effects of medications can play a crucial role in the development of sexual dysfunction. Aim Assessment of the occurrence of sexual dysfunction in female patients with acne vulgaris. Methods The study included 82 women diagnosed with acne vulgaris and 133 female controls without skin diseases. The sexual health of the subjects was assessed using the Female Sexual Function Index (FSFI) via an online anonymous questionnaire. Additional information regarding patients' medical history was analyzed. Results There was no statistically significant difference in the total FSFI score between patients and controls (p > 0.05). Patients had significantly higher scores than controls in the satisfaction domain (p < 0.05). There was a positive correlation between the question about the subjective effect of skin condition on sexual desire and the likelihood of sexual dysfunction in the FSFI (p < 0.05, r = 0.33). Patients using retinoids had a slightly reduced FSFI (p = 0.44), which correlated negatively with retinoid use (p = 0.0428, r = -0.4257). Women receiving oral retinoids had downward trends in the satisfaction and pain domains (p = 0.41 and p = 0.198, respectively). Retinoid treatment was negatively correlated with the overall FSFI lubrication domain score (p = 0.0423, r = -0.4268). In addition, there was also a negative correlation between retinoid therapy and the overall FSFI orgasm domain score (p = 0.0024, r = -0.6014). Limitations The inability to evaluate the severity of acne vulgaris; the relatively small sample size; no matching of cases and controls with respect to age; and the lack of physician-confirmed data regarding the effectiveness of the administered treatment. Conclusions Some female patients with acne vulgaris may be at higher risk of sexual dysfunction. Decreased self-esteem and the general psychological burden of this dermatosis may negatively influence sexual functioning, so it is important to pay attention to this aspect. Patients who need help in this area should be referred to appropriate specialists.</p>","PeriodicalId":50376,"journal":{"name":"Indian Journal of Dermatology Venereology & Leprology","volume":" ","pages":"1-5"},"PeriodicalIF":3.4,"publicationDate":"2025-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144876514","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}