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Future Virology最新文献

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Hepatitis delta: recent advances and future therapies 乙型肝炎：最新进展和未来疗法
Future Virology Pub Date : 2024-06-14 DOI: 10.1080/17460794.2024.2356401
Zillah Cargill, I. Carey, Kosh Agarwal
{"title":"Hepatitis delta: recent advances and future therapies","authors":"Zillah Cargill, I. Carey, Kosh Agarwal","doi":"10.1080/17460794.2024.2356401","DOIUrl":"https://doi.org/10.1080/17460794.2024.2356401","url":null,"abstract":"","PeriodicalId":503758,"journal":{"name":"Future Virology","volume":"57 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141342232","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Characterization of four virulent bacteriophages as potential therapeutics for clinical multidrug-resistant, extensively drug-resistant Acinetobacter baumannii 四种毒性噬菌体的特征描述--它们是治疗临床耐多药和广泛耐药鲍曼不动杆菌的潜在药物
Future Virology Pub Date : 2024-06-11 DOI: 10.1080/17460794.2024.2357918
Sezin Unlu, Aylin Uskudar-Guclu, Suleyman Yalcin, O. Kurt-Azap, A. Basustaoglu
{"title":"Characterization of four virulent bacteriophages as potential therapeutics for clinical multidrug-resistant, extensively drug-resistant\u0000 Acinetobacter baumannii","authors":"Sezin Unlu, Aylin Uskudar-Guclu, Suleyman Yalcin, O. Kurt-Azap, A. Basustaoglu","doi":"10.1080/17460794.2024.2357918","DOIUrl":"https://doi.org/10.1080/17460794.2024.2357918","url":null,"abstract":"","PeriodicalId":503758,"journal":{"name":"Future Virology","volume":"80 18","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141358054","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Resistance analysis in the phase III COMET-TAIL study: treatment of COVID-19 with intramuscular or intravenous sotrovimab COMET-TAIL III 期研究的抗药性分析：使用肌肉注射或静脉注射索托维单抗治疗 COVID-19
Future Virology Pub Date : 2024-06-05 DOI: 10.1080/17460794.2024.2350923
Maria L Agostini, G. Schnell, J. D. Iulio, Anita Kohli, Adrienne E Shapiro, Elias H Sarkis, Naomi Givens, Amanda Peppercorn, A. Skingsley, Leah A. Gaffney, M. Aldinger, C. Hebner, A. Cathcart
{"title":"Resistance analysis in the phase III COMET-TAIL study: treatment of COVID-19 with intramuscular or intravenous sotrovimab","authors":"Maria L Agostini, G. Schnell, J. D. Iulio, Anita Kohli, Adrienne E Shapiro, Elias H Sarkis, Naomi Givens, Amanda Peppercorn, A. Skingsley, Leah A. Gaffney, M. Aldinger, C. Hebner, A. Cathcart","doi":"10.1080/17460794.2024.2350923","DOIUrl":"https://doi.org/10.1080/17460794.2024.2350923","url":null,"abstract":"","PeriodicalId":503758,"journal":{"name":"Future Virology","volume":"41 21","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141384574","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Identification of a novel Indian clade of Coxsackievirus A16 in Hand, Foot and Mouth disease outbreak in 2022 在 2022 年爆发的手足口病疫情中发现新型印度克沙奇病毒 A16 支系
Future Virology Pub Date : 2024-06-05 DOI: 10.1080/17460794.2024.2350247
P. Mamidi, Baijayantimala Mishra, S. Panda, Amrita Ray, Deepak Jena, V. K. Biswas, E. Laha, Monalisa Mohanty, Soma Chattopadhyay, Sunil Raghav, B. Kar, Manoj Nayak, M. Mandal, Debashis Santra, B. Dwibedi, Kavita Gupta
{"title":"Identification of a novel Indian clade of Coxsackievirus A16 in Hand, Foot and Mouth disease outbreak in 2022","authors":"P. Mamidi, Baijayantimala Mishra, S. Panda, Amrita Ray, Deepak Jena, V. K. Biswas, E. Laha, Monalisa Mohanty, Soma Chattopadhyay, Sunil Raghav, B. Kar, Manoj Nayak, M. Mandal, Debashis Santra, B. Dwibedi, Kavita Gupta","doi":"10.1080/17460794.2024.2350247","DOIUrl":"https://doi.org/10.1080/17460794.2024.2350247","url":null,"abstract":"","PeriodicalId":503758,"journal":{"name":"Future Virology","volume":"37 S1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141385908","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
G-Quadruplexes in hemorrhagic fever viruses of Bunyavirales 布尼亚病毒科出血热病毒中的 G-四倍体
Future Virology Pub Date : 2024-05-22 DOI: 10.1080/17460794.2024.2351737
Lu Lv, Liyuan Zhang, Zhengyang Pan, Chunhui Yin, Jingyi He, Zhihao Wang, Huixiang Cheng, Leiliang Zhang
{"title":"G-Quadruplexes in hemorrhagic fever viruses of Bunyavirales","authors":"Lu Lv, Liyuan Zhang, Zhengyang Pan, Chunhui Yin, Jingyi He, Zhihao Wang, Huixiang Cheng, Leiliang Zhang","doi":"10.1080/17460794.2024.2351737","DOIUrl":"https://doi.org/10.1080/17460794.2024.2351737","url":null,"abstract":"","PeriodicalId":503758,"journal":{"name":"Future Virology","volume":"92 10","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141111581","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Role of nonlinear transmission term in stability of hand, foot and mouth disease dynamics 非线性传播项在手足口病动态稳定性中的作用
Future Virology Pub Date : 2024-04-22 DOI: 10.2217/fvl-2023-0198
Xiaofang Liu, Lvping Lin, Xu Gao, Yuping Li, Shangyu Teng, Guodong Sun
{"title":"Role of nonlinear transmission term in stability of hand, foot and mouth disease dynamics","authors":"Xiaofang Liu, Lvping Lin, Xu Gao, Yuping Li, Shangyu Teng, Guodong Sun","doi":"10.2217/fvl-2023-0198","DOIUrl":"https://doi.org/10.2217/fvl-2023-0198","url":null,"abstract":"Aim: This study focuses on the nonlinear characteristics of two linearly stable equilibrium states within a theoretical hand, foot and mouth disease (HFMD) dynamics model. Methods: The conditional nonlinear optimal perturbation method, the Lyapunov method and the linear singular vector method are employed. Results: By utilizing the conditional nonlinear optimal perturbation method, it is determined that the two linearly stable equilibrium states (namely the free disease and disease HFMD states) also exhibit nonlinear stability. It is found that the stabilities of the free disease and disease HFMD equilibrium states differ in terms of returning to their original states. Conclusion: It is discovered that nonlinearity plays a crucial role in reinstating the original equilibrium states.","PeriodicalId":503758,"journal":{"name":"Future Virology","volume":"42 20","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140672923","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Analysis of the application value of HPV mRNA and DNA detection in early screening of cervical lesions HPV mRNA 和 DNA 检测在宫颈病变早期筛查中的应用价值分析
Future Virology Pub Date : 2024-04-18 DOI: 10.2217/fvl-2024-0020
Dengcai Zhang, Lihua Zhang, Yanjiong Wang, Guangshu Hao, Zhiyuan Li
{"title":"Analysis of the application value of HPV mRNA and DNA detection in early screening of cervical lesions","authors":"Dengcai Zhang, Lihua Zhang, Yanjiong Wang, Guangshu Hao, Zhiyuan Li","doi":"10.2217/fvl-2024-0020","DOIUrl":"https://doi.org/10.2217/fvl-2024-0020","url":null,"abstract":"Aim: At present, COBAS human papillomavirus (HPV) and Aptima HPV screening are widely used to detect HPV infection. In this study, we compared and analyzed the positive rates of DNA and mRNA (n = 10,128 women). Methods: After HPV screening, colposcopy was performed. Subsequently, pathological analysis was conducted on the screening results. Results: In Aptima HPV 16 group, the proportion of pathological lesions ≥CIN2 was 32.69%, while in COBAS HPV group, it was 24.18% (p < 0.05). Aptima HPV other risk types and COBAS HPV other risk types, the proportion of cases ≥CIN2 was 12.42 and 5.79%, respectively (p < 0.001). Conclusion: The results illustrated that the Aptima HPV test detects more accurately clinically relevant lesions than the COBAS test.","PeriodicalId":503758,"journal":{"name":"Future Virology","volume":" 29","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140689275","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Treatment response and adverse effects of direct acting antivirals among HCV patients carrying comorbid conditions 合并症患者对直接作用抗病毒药物的治疗反应和不良反应
Future Virology Pub Date : 2024-04-17 DOI: 10.2217/fvl-2023-0193
Dur E Nishwa, Hafiza Arooba Riaz, Muhammad Salman Tiwana, Ameer Fatima, Braira Wahid
{"title":"Treatment response and adverse effects of direct acting antivirals among HCV patients carrying comorbid conditions","authors":"Dur E Nishwa, Hafiza Arooba Riaz, Muhammad Salman Tiwana, Ameer Fatima, Braira Wahid","doi":"10.2217/fvl-2023-0193","DOIUrl":"https://doi.org/10.2217/fvl-2023-0193","url":null,"abstract":"Aim: Our study aimed to assess the response to direct-acting antiviral drugs (DAAs) among hepatitis C virus (HCV)-infected patients who also had other comorbid conditions. Materials & methods: The data was examined based on a variety of categories, encompassing age, gender, liver function enzymes, tumor markers and comorbid conditions. Results: In conclusion, DAAs demonstrated relatively effective results in HCV/hepatitis B virus coinfected patients, with a 78.2% sustained virological response rate, and 55.5% among HCV monoinfected patients in our study sample. However, some challenges remain, as we observed certain adverse effects associated with DAAs. Conclusion: In the past, interferon-based treatment regimens were the primary options against HCV; however, their limited success led to the development of DAAs drugs that reportedly cause adverse outcomes occasionally.","PeriodicalId":503758,"journal":{"name":"Future Virology","volume":" 25","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140691857","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
RNAi-mediated inhibition of SARS-CoV-2: applications and challenges RNAi- 介导的 SARS-CoV-2 抑制：应用与挑战
Future Virology Pub Date : 2024-04-12 DOI: 10.2217/fvl-2023-0169
Debosmita Sanyal, Binay Chaubey
{"title":"RNAi-mediated inhibition of SARS-CoV-2: applications and challenges","authors":"Debosmita Sanyal, Binay Chaubey","doi":"10.2217/fvl-2023-0169","DOIUrl":"https://doi.org/10.2217/fvl-2023-0169","url":null,"abstract":"The global pandemic due to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has led to ∼6.9 million deaths and affected ∼767 million people globally. The approved vaccines have contributed significantly in reducing disease severity and mortality. However, new infections post vaccination and the lack of specific antivirals have encouraged the research using multiple approaches to design novel therapeutics against COVID-19. Recent studies on the applications of RNAi against coronavirus provide substantial evidence on the prospects of this technique against SARS-CoV-2. Progress in the field of computational analysis and applications of multiple delivery methods also promises safe and effective implementation of RNAi against COVID-19. This review deals with the possible applications and challenges of RNAi against SARS-CoV-2.","PeriodicalId":503758,"journal":{"name":"Future Virology","volume":"123 12","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140708857","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Developing a risk prediction model for COVID-19 infection in heart transplant recipients using artificial intelligence 利用人工智能开发心脏移植受者感染 COVID-19 的风险预测模型
Future Virology Pub Date : 2024-02-09 DOI: 10.2217/fvl-2023-0162
Shriya Sharma, Nora Menon, Jose Ruiz, Caitlyn Luce, Lisa Brumble, Anirban Bhattacharya, Rohan Goswami
{"title":"Developing a risk prediction model for COVID-19 infection in heart transplant recipients using artificial intelligence","authors":"Shriya Sharma, Nora Menon, Jose Ruiz, Caitlyn Luce, Lisa Brumble, Anirban Bhattacharya, Rohan Goswami","doi":"10.2217/fvl-2023-0162","DOIUrl":"https://doi.org/10.2217/fvl-2023-0162","url":null,"abstract":"Aim: Describe the utility of an inverse reinforcement learning pathway to develop a novel model to predict and manage the spread of COVID-19. Materials & methods: Convolutional neural network (CNN) with multilayer perceptron (MLP) modeling functions utilized inverse reinforcement learning to predict COVID-19 outcomes based on a comprehensive array of factors. Results: Our model demonstrates a sensitivity of 0.67 in the receiver operating characteristic curve and can correctly identify approximately 67% of the positive cases. Conclusion: We demonstrate the ability to augment clinical decision-making with a novel artificial intelligence (AI) solution that accurately predicted the susceptibility of transplant patients to COVID-19. This enables physicians to administer treatment and take appropriate preventative measures based on patients' risk factors.","PeriodicalId":503758,"journal":{"name":"Future Virology","volume":"345 11","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139848341","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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