Israel Medical Association Journal最新文献_第7页

Can Blood Inflammatory Markers Identify Pregnant Women with Preeclampsia? Still a Controversial Issue. 血液炎症标志物能否识别子痫前期孕妇？仍是一个有争议的问题。

IF 1.8 4区医学

Israel Medical Association Journal Pub Date : 2024-09-01

Andrei Braester, Artyom Bilyk, Celia Suriu, Luiza Akria, Najib Dally, Masad Barhoum

{"title":"Can Blood Inflammatory Markers Identify Pregnant Women with Preeclampsia? Still a Controversial Issue.","authors":"Andrei Braester, Artyom Bilyk, Celia Suriu, Luiza Akria, Najib Dally, Masad Barhoum","doi":"","DOIUrl":"","url":null,"abstract":"Background: Preeclampsia is a unique vascular disease during pregnancy that generally appears after 20 of weeks gestation or until 6 weeks after delivery. Left undiagnosed, preeclampsia can lead rapidly to death of both mother and fetus.Objectives: To verify the efficacy of peripheral blood inflammatory markers (BIMs)in diagnosing preeclampsia and compare them with results from other studies.Methods: Our retrospective case-control study comprised two patient groups. Pregnant women with preeclampsia and pregnant women without preeclampsia were compared for BIMs: neutrophil to lymphocyte ratio (NLR), platelet to lymphocyte ratio (PLR), and mean platelet volume (MPV). The primary endpoint of our research was to assess the predictive power of BIMs for preeclampsia diagnosis.Results: The sample size was calculated based on expected differences of BIMs between the control and study groups. Comparison of quantitative variables was conducted with independent sample t-test or alternatively by Wilcoxon rank sum test. The MPV values were slightly higher in the preeclampsia group, but not statistically significant. NLR and PLR did differentiate between study and control groups.Conclusions: The diagnostic accuracy of BIMs is unsatisfactory for preeclampsia diagnosis. Discrepancies concerning these values need to be clarified. Further large prospective studies are necessary to validate the potential factor accuracy in preeclampsia diagnosis.","PeriodicalId":50268,"journal":{"name":"Israel Medical Association Journal","volume":"26 8","pages":"500-503"},"PeriodicalIF":1.8,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142299956","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Current Perspectives on Maintaining Medical Education and Medical Communication Skills during War Times. 战争时期保持医学教育和医学交流技能的当前视角。

IF 1.8 4区医学

Israel Medical Association Journal Pub Date : 2024-09-01

Moshe Salai, Yoram Sandhaus, Eitan Lunenfeld, Naomi Levine-Rahimi, Shai Ashkenazi, Avinoam Tzabari, Ahuva Golik, Zachi Grossman, Talma Kushnir

引用次数: 0

Prevalence and Predictors of Tunneled Dialysis Catheter Dysfunction. 隧道式透析导管功能障碍的发生率和预测因素。

IF 1.8 4区医学

Israel Medical Association Journal Pub Date : 2024-09-01

Ilan Rozenberg, Sydney Benchetrit, Tali Zitman-Gal, Moanis Ajaj, Maysam Shehab, Naomi Nacasch, Keren Cohen-Hagai

{"title":"Prevalence and Predictors of Tunneled Dialysis Catheter Dysfunction.","authors":"Ilan Rozenberg, Sydney Benchetrit, Tali Zitman-Gal, Moanis Ajaj, Maysam Shehab, Naomi Nacasch, Keren Cohen-Hagai","doi":"","DOIUrl":"","url":null,"abstract":"Background: Hemodialysis requires reliable, recurrent access to the circulatory system. Central venous tunneled dialysis catheters (TDC) are frequently used for patients receiving hemodialysis as a bridge to permanent vascular access or as a final option. TDC are prone to complications such as infection and dysfunction.Objectives: To assess the prevalence and predictors of TDC dysfunction in a cohort of chronic hemodialysis patients.Methods: This single-center, retrospective study was based on data from an electronic database of chronic hemodialysis patients during 5 years of follow-up.Results: A total of 625 TDC were inserted in 361 patients, of which 234 (37.4%) were replaced due to dysfunction. The main insertion site was the right internal jugular vein. Diabetes mellitus was an important predictor of TDC dysfunction and was significantly correlated with TDC extraction. Chronic anticoagulation and antiplatelet treatment did not affect the rate of TDC dysfunction or replacement.Conclusions: TDC use for chronic dialysis patients is increasing and dysfunction is a major problem. In our study, we highlighted the high prevalence of TDC dysfunction and the need for further research to improve hemodialysis access as well as TDC patency and function.","PeriodicalId":50268,"journal":{"name":"Israel Medical Association Journal","volume":"26 8","pages":"508-513"},"PeriodicalIF":1.8,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142299963","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Impact of a Heart Failure Clinic on Clinical Outcomes: Our Experience. 心衰诊所对临床结果的影响：我们的经验

IF 1.8 4区医学

Israel Medical Association Journal Pub Date : 2024-09-01

Gassan Moady, Michal De Picciotto, Naila Aslan, Shaul Atar

{"title":"The Impact of a Heart Failure Clinic on Clinical Outcomes: Our Experience.","authors":"Gassan Moady, Michal De Picciotto, Naila Aslan, Shaul Atar","doi":"","DOIUrl":"","url":null,"abstract":"Background: Heart failure (HF) is an emerging pandemic associated with increased mortality, recurrent hospitalizations, and reduced quality of life. Guideline-directed medical therapy has been shown to improve outcomes, particularly in patients with HF with reduced ejection fraction (HFrEF). The main goal of HF clinics is optimizing medical therapy.Objectives: To assess the impact of our HF clinic on medical therapy and clinical outcomes.Methods: We obtained demographic, echocardiographic, and clinical data of patients listed in our HF clinic during a 4-year period. Medical therapy was evaluated based on patient reports and documented data. Recurrent admissions for HF were documented.Results: A total of 317 patients (74.1% male, median age 66 years, IQR 55-74) were listed in the clinic with a total of 1140 visits. Of these patients, 62.5% had HFrEF, 20.5% presented with mildly reduced ejection fraction, and 17% showed preserved ejection fraction at the time of the first visit. The use of sodium glucose co-transporter 2 inhibitors and mineralocorticoid receptor antagonists was optimized in 92% and 91% of the patients, respectively. In the subgroup of patients with HFrEF, the use of angiotensin-receptor antagonist/neprilysin inhibitor increased from 22.6% to 87.9% (P < 0.001) and SGLT2 inhibitor use increased from 49.2% to 92% (P < 0.001). During the follow-up period (2.2 years, IQR 1.1-3.1), 203 patients (64%) were readmitted to the hospital for HF at least once. The rate of readmissions decreased over time.Conclusions: An HF clinic plays an important role in optimizing medical therapy and reducing readmissions.","PeriodicalId":50268,"journal":{"name":"Israel Medical Association Journal","volume":"26 8","pages":"504-507"},"PeriodicalIF":1.8,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142299964","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Difficult-to-Treat Rheumatoid Arthritis: Challenges in Diagnosis and Treatment. 难以治疗的类风湿关节炎：诊断和治疗的挑战。

IF 1.8 4区医学

Israel Medical Association Journal Pub Date : 2024-09-01

Aniela Shouval, Shiri Keret, Itzhak Rosner, Gleb Slobodin

引用次数: 0

La Bella Simonetta: Atypical Iris Coloboma Portrayed by Sandro Botticelli. La Bella Simonetta：桑德罗-波提切利描绘的非典型虹膜褐斑。

IF 1.8 4区医学

Israel Medical Association Journal Pub Date : 2024-08-01

Moisey Moldavsky

引用次数: 0

Neuraxial Anesthesia Following Thrombocyte Transfusion in Women with Severe Thrombocytopenia Prior to a Cesarean Delivery: A Retrospective Study and Literature Review. 剖宫产前严重血小板减少妇女输注血小板后的神经麻醉：回顾性研究和文献综述。

IF 1.8 4区医学

Israel Medical Association Journal Pub Date : 2024-08-01

Jacob Weinstein, Daniel Shatalin, Sorina Grisaru-Granovsky, Yaacov Gozal, Alexander Ioscovich

{"title":"Neuraxial Anesthesia Following Thrombocyte Transfusion in Women with Severe Thrombocytopenia Prior to a Cesarean Delivery: A Retrospective Study and Literature Review.","authors":"Jacob Weinstein, Daniel Shatalin, Sorina Grisaru-Granovsky, Yaacov Gozal, Alexander Ioscovich","doi":"","DOIUrl":"","url":null,"abstract":"Background: Cesarean delivery (CD) is one of the most common surgeries performed worldwide, with increasing yearly rates. Although neuraxial techniques remain the preferred anesthesia method for CD, maternal thrombocytopenia remains a prominent contraindication. Formation of spinalepidural hematomas are extremely rare, however the minimal thrombocyte count required for safe neuraxial anesthesia is still under debate. Although transfusion of thrombocytes for the purpose of neuraxial anesthesia is still not recommended, patients with severe thrombocytopenia (less than 50 × 103/uL) are given thrombocyte transfusion for surgical hemostasis.Objectives: To evaluate the anesthetic approach to caesarean deliveries in parturients with severe thrombocytopenia who received thrombocyte transfusion aimed for improved surgical hemostasis.Methods: We conducted a single center, retrospective cohort study. Results: A total of five cases were found, four of which were given spinal anesthesia immediately following thrombocyte transfusion. One patient was denied spinal anesthesia because her thrombocyte count following transfusion failed to reach safe levels. None of our cases had anesthesia-related complications recorded.Conclusions: We examined the anesthetic management parturients with severe thrombocytopenia who needed cesarean delivery and were transfused with thrombocytes for surgical hemostasis. In such cases, spinal anesthesia may be considered due to the serious risks associated with general anesthesia.","PeriodicalId":50268,"journal":{"name":"Israel Medical Association Journal","volume":"26 7","pages":"410-414"},"PeriodicalIF":1.8,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141856959","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Idiopathic Eosinophilic Vasculitis: A Case Series. 特发性嗜酸性粒细胞性血管炎：病例系列。

IF 1.8 4区医学

Israel Medical Association Journal Pub Date : 2024-08-01

Shir Ben Asher Kestin, David Levy, Adi Broyde, Shani Peretz Bardan, Keren Netzer, Yona Kitai-Cohen, Ori Elkayam, Nancy Agmon-Levin, Hagith Yonath, Shaye Kivity

引用次数: 0

Long-term Sperm Preservation: Exploring the Clinical, Economic, and Ethical Dimensions. 长期保存精子：探索临床、经济和伦理层面。

IF 1.8 4区医学

Israel Medical Association Journal Pub Date : 2024-08-01

Roy Bitan, Tal Suissa, Itai Gat

引用次数: 0

Caring for children released from captivity: no pediatrician can be ready for such a scenario. 照顾被囚禁的获释儿童：没有儿科医生能应对这种情况。

IF 1.8 4区医学

Israel Medical Association Journal Pub Date : 2024-08-01

Dror Mandel, Ronit Lubetzky, David Greenberg, Itai Pessach, Efrat Baron Harlev, Gilat Livny

引用次数: 0