Israel Medical Association Journal最新文献_第6页

Cytomegalovirus-associated Portal Vein Thrombosis in an Immunocompetent Patient. 一名免疫功能正常患者的巨细胞病毒相关门静脉血栓。

IF 1.8 4区医学

Israel Medical Association Journal Pub Date : 2025-02-01

Menas Atarieh, Ayelet Raz-Pasteur

引用次数: 0

Role of Platelet-to-Lymphocyte Ratio and Other Markers in Predicting Severity and Prognosis in COVID-19 Patients. 血小板/淋巴细胞比等指标在预测COVID-19患者严重程度和预后中的作用

IF 1.8 4区医学

Israel Medical Association Journal Pub Date : 2025-02-01

Raymond Farah, Rola Khamisy-Farah, George Arshed, Rashed Khatib, Salman Zarka

{"title":"Role of Platelet-to-Lymphocyte Ratio and Other Markers in Predicting Severity and Prognosis in COVID-19 Patients.","authors":"Raymond Farah, Rola Khamisy-Farah, George Arshed, Rashed Khatib, Salman Zarka","doi":"","DOIUrl":"","url":null,"abstract":"Background: Coronavirus disease 2019 (COVID-19) is a respiratory illness with broad spectrum of clinical manifestations ranging from asymptomatic cases to severe complications such as acute respiratory failure, multi-organ dysfunction, and death.Objectives: To evaluate the platelet-lymphocyte ratio (PLR) as a marker of disease severity and mortality in COVID-19 patients. To explore the relationship between PLR and other inflammatory indicators, specifically C-reactive protein (CRP) and neutrophil-lymphocyte ratio (NLR).Methods: The cohort included 400 patients (206 males, 194 females; mean age: 64.5 ± 17.1 years [range 20-100 years]) who were hospitalized between April 2020 and December 2021. Data were collected on demographic and clinical characteristics, including ward and critical care details. CRP, NLR, and PLR values were recorded on the first and last days of hospitalization. Patients were categorized based on their hospitalization outcomes.Results: PLR statistically increased during hospitalization, from 245 ± 160 at admission to 341 ± 747 at discharge (P < 0.001). A significant association was found between PLR and both the length of hospital stay and mortality. The mean PLR in the deceased group was 445 ± 590, compared to 304 ± 795 in the survivors, P = 0.007. This finding showed a correlation between higher PLR and increased severity and mortality.Conclusions: PLR has been identified as a relevant marker for assessing the severity of COVID-19. Elevated PLR levels are associated with cytokine storm, length of hospital stay, and mortality. The results highlight the relationship between elevated PLR and poor outcome in COVID-19 patients, suggesting its use in monitoring disease progression and prognosis.","PeriodicalId":50268,"journal":{"name":"Israel Medical Association Journal","volume":"27 2","pages":"73-77"},"PeriodicalIF":1.8,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143765649","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Acupuncture for Treating Cellulitis: A Pilot Study. 针刺治疗蜂窝织炎的初步研究。

IF 1.8 4区医学

Israel Medical Association Journal Pub Date : 2025-02-01

Dvir Shechter, Elad Schiff, Nizar Elias, Sharon Gino-Moor, Sagi Gavrieli, Samuel Attias, Ilana Levy Yurkovski

{"title":"Acupuncture for Treating Cellulitis: A Pilot Study.","authors":"Dvir Shechter, Elad Schiff, Nizar Elias, Sharon Gino-Moor, Sagi Gavrieli, Samuel Attias, Ilana Levy Yurkovski","doi":"","DOIUrl":"","url":null,"abstract":"Background: Acute skin infections, like cellulitis or erysipelas, are common and respond well to antibiotic treatment. However, complete resolution of the inflammatory process is often slow and associated with prolonged pain and reduced mobility. Several studies have indicated that acupuncture may effectively treat inflammatory skin diseases.Objectives: To evaluate the efficacy of acupuncture for treating cellulitis in patients hospitalized in internal medicine departments.Methods: In this pilot randomized sham-controlled trial, patients hospitalized with cellulitis in internal medicine departments were randomized to acupuncture or sham acupuncture, in addition to standard care. The primary outcome was the degree of improvement in the cellulitis score at day 4 of hospitalization. Secondary endpoints included patient pain self-assessment and local and systemic inflammatory signs.Results: The study comprised 29 patients; 15 treated with acupuncture, 14 by a sham procedure. At day 4, patients in the acupuncture arm had an improved cellulitis score (4.1 ± 2.8) compared with the sham-control group (7.9 ± 3.3, P = 0.003). Pain intensity based on the Visual Assessment Scale was lower in the acupuncture group 3.8 ± 2.7 vs. 6.3 ± 2.8; P = 0.023. There was no difference in the rate of leukocyte change. However, C-reactive protein significantly decreased to 27.0 ± 22.1 mg/L at day 4 following acupuncture compared to 63.9 ± 51.9 mg/L (P = 0.025).Conclusions: In our pilot study, we found acupuncture to be efficacious as an adjunctive therapy in the treatment of leg cellulitis. A large-scale trial on the effectiveness of acupuncture for skin infections is needed.","PeriodicalId":50268,"journal":{"name":"Israel Medical Association Journal","volume":"27 2","pages":"114-119"},"PeriodicalIF":1.8,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143765544","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Computed Tomography Findings of Combat Casualties During the 2023-2024 Israel-Gaza Armed Conflict. 2023-2024年以色列-加沙武装冲突期间战斗伤亡的计算机断层扫描结果。

IF 1.8 4区医学

Israel Medical Association Journal Pub Date : 2025-01-01

Hagar Olshaker, Dana Brin, Larisa Gorenstein, Vera Sorin, Eyal Klang, Nisim Rahman, Michal Marianne Amitai

{"title":"Computed Tomography Findings of Combat Casualties During the 2023-2024 Israel-Gaza Armed Conflict.","authors":"Hagar Olshaker, Dana Brin, Larisa Gorenstein, Vera Sorin, Eyal Klang, Nisim Rahman, Michal Marianne Amitai","doi":"","DOIUrl":"","url":null,"abstract":"Background: On 7 October 2023, an armed conflict erupted between Hamas and Israel, leading to numerous combat casualties.Objectives: To describe computed tomography (CT) findings of combat casualties at a tertiary medical center during the first 3 months of the conflict.Methods: A retrospective observational study was conducted on patients admitted between 7 October 2023 and 7 January 2024. Adults with conflict-related trauma who underwent chest, abdomen, and pelvis (body) trauma protocol CT scans were included.Results: Of 272 patients who underwent body trauma protocol CT, 112 combat-related adults were included, mean age of 27 years and one female. In total, 82 patients (73%) underwent additional scans of the head and neck or extremities. Fractures were observed in 53 patients (47%). Vascular injuries were present in 40 patients (35%). Limb injuries were most common, affecting 37 patients (33%), which prompted a protocol update. Lung injuries were the most common in body CT: 30 patients (27%). Head and neck injuries were seen in 21 patients (18%). Multisystem trauma was present in 24 patients (21%). A total of 83 patients (74%) underwent surgery, mostly orthopedic/soft tissue surgeries (63%); 15 (13%) underwent abdominal surgery, with bowel injuries confirmed in eight cases.Conclusions: CT scans are an important tool in conflict trauma management. Limb injuries were the most frequent, necessitating protocol adjustments. Lung injuries were the most common body injury; 21% of patients had multisystem trauma. Most patients required surgery.","PeriodicalId":50268,"journal":{"name":"Israel Medical Association Journal","volume":"27 1","pages":"17-22"},"PeriodicalIF":1.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143392347","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Systematic Review of Remote Cardiac Rehabilitation Utilizing Wearable Monitors. 利用可穿戴监视器的远程心脏康复系统综述。

IF 1.8 4区医学

Israel Medical Association Journal Pub Date : 2025-01-01

Oren Yagel, Habib Helou, Bruria Hirsh-Raccah, Emil Aliev, Shirel Shtraikh, Arik Eisenkraft, Rinat Tzach-Nahman, Offer Amir, Dean Nachman

引用次数: 0

Utilizing 2D Strain in Routine Echocardiography Examinations: Position paper of the Israeli Society of Echocardiography. 利用二维应变在常规超声心动图检查：以色列超声心动图学会立场文件。

IF 1.8 4区医学

Israel Medical Association Journal Pub Date : 2025-01-01

Marina Leitman, Shemy Carasso

引用次数: 0

Lack of Clinical Prognostic Power for Ventilated Critical COVID-19 Patients in the Intensive Care Unit. 重症监护病房通气危重患者临床预后能力不足

IF 1.8 4区医学

Israel Medical Association Journal Pub Date : 2025-01-01

Yigal Helviz, Frederic S Zimmerman, Daniel Belman, Yaara Giladi, Imran Ramlawi, David Shimony, Meira Yisraeli Salman, Nir Weigert, Mohammad Jaber, Shai Balag, Yaniv Hen, Raed Jebrin, Daniel Fink, Eli Ben Chetrit, Michal Shitrit, Ramzi Kurd, Phillip D Levin

{"title":"Lack of Clinical Prognostic Power for Ventilated Critical COVID-19 Patients in the Intensive Care Unit.","authors":"Yigal Helviz, Frederic S Zimmerman, Daniel Belman, Yaara Giladi, Imran Ramlawi, David Shimony, Meira Yisraeli Salman, Nir Weigert, Mohammad Jaber, Shai Balag, Yaniv Hen, Raed Jebrin, Daniel Fink, Eli Ben Chetrit, Michal Shitrit, Ramzi Kurd, Phillip D Levin","doi":"","DOIUrl":"","url":null,"abstract":"Background: Prognostication is complex in patients critically ill with coronavirus disease 2019 (COVID-19).Objectives: To describe the natural history of ventilated critical COVID-19 patients.Methods: Due to our legal milieu, active withdrawal of care is not permitted, providing an opportunity to examine the natural history of ventilated critical COVID-19 patients. This retrospective cohort included COVID-19 ICU patients who required mechanical ventilation. Respiratory and laboratory parameters were followed from initiation of mechanical ventilation for 14 days or until extubation, death or tracheostomy.Results: A total of 112 patients were included in the analysis. Surviving patients were younger than non-survivors (62 years [range 54-69] vs. 66 years [range 62-71], P = 0.01). Survivors had a shorter time to intubation, shorter ventilation duration, and longer hospital stay. Respiratory parameters at intubation were not predictive of mortality. Nevertheless, on ventilation day 10, many of the ventilatory parameters were significantly better in survivors. Regarding laboratory parameters, neutrophil counts were significantly higher in non-survivors on day 1 and C-reactive protein levels were significantly lower in survivors on day 10. Modeling using a generalized estimating equation showed small dynamic differences in ventilatory parameters predictive of survival.Conclusions: In ventilated COVID-19 patients when there is no active care withdrawal, prognostication may be possible after a week; however, differences between survivors and non-survivors remain small.","PeriodicalId":50268,"journal":{"name":"Israel Medical Association Journal","volume":"27 1","pages":"34-41"},"PeriodicalIF":1.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143392353","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Internal Medicine at Home: Three Years of Experience with a Novel Model. 家庭内科：新模式的三年经验。

IF 1.8 4区医学

Israel Medical Association Journal Pub Date : 2025-01-01

Jamal Qarawany, Yoav Weber, Zivit Zalts, Carmit Steinberg, Doron Cohn-Schwartz, Eyal Braun, Zaher S Azzam, Avi Magid, Henda Darawsha, Rizan Sakhnini, Gidon Berger

{"title":"Internal Medicine at Home: Three Years of Experience with a Novel Model.","authors":"Jamal Qarawany, Yoav Weber, Zivit Zalts, Carmit Steinberg, Doron Cohn-Schwartz, Eyal Braun, Zaher S Azzam, Avi Magid, Henda Darawsha, Rizan Sakhnini, Gidon Berger","doi":"","DOIUrl":"","url":null,"abstract":"Background: Hospital-at-Home (HaH) programs offer medical services in the patient's home as an alternative to hospitalization across various medical fields. Previous studies have demonstrated that HaH provides several benefits for patients and the healthcare system. Rambam Health Care Center was the pioneer hospital in introducing HaH in Israel. Since April 2021, in collaboration with Maccabi Healthcare Services, the center has been providing home hospitalization services for patients with acute internal medicine illnesses based on an innovative model.Objectives: To describe demographic data, background diseases, indications for HaH admissions, length of stay (LOS), 1-month and 1-week readmission rates, home mortality, and 1-month mortality.Results: The study included 262 patients (135 men, 127 women), mean age 69.7 years (range 24-98, median 73). Patients had significant co-morbidities, with a Charlson Comorbidity Index score of 6.7. Among the patients, 170 were independent, 61 were incapacitated, and the remainder had various functional limitations. Most admissions were from internal medicine departments, 39 originating from the emergency department and the rest from other acute care wards. The primary indications for HaH admission included pneumonia, urinary tract infections, and cellulitis. The average hospital LOS was 48.9 hours, while the HaH LOS was 3.43 days. Readmission rates for the same initial conditions were 10% within 1 week and 14% within 1 month. Twenty-one patients died within 1 month of discharge from HaH, including one death during the HaH period.Conclusions: This study highlighted the feasibility of home hospitalization as a viable alternative to traditional inpatient care in internal medicine.","PeriodicalId":50268,"journal":{"name":"Israel Medical Association Journal","volume":"27 1","pages":"49-53"},"PeriodicalIF":1.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143392350","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Advancing Preclinical Education: A New Model for Medical Education. The Experience of the Dina Recanati School of Medicine at Reichman University. 推进临床基础教育：医学教育新模式赖曼大学Dina Recanati医学院的经验。

IF 1.8 4区医学

Israel Medical Association Journal Pub Date : 2025-01-01

Efrat Wertheimer, David Maiershon, Jonathan Giron, Yehuda Shoenfeld, Arnon Afek, Miri Mizrahi Reuveni

引用次数: 0

Iodinated Contrast Media Allergy and Its Management in a Large Cohort in the Hospital Setting. 医院大队列碘造影剂过敏及其管理

IF 1.8 4区医学

Israel Medical Association Journal Pub Date : 2025-01-01

Isca Hershkowitz, Joshua Moss, Jacob Sosna, Eyal Netser, Avivit Cahn, Alon Y Hershko

{"title":"Iodinated Contrast Media Allergy and Its Management in a Large Cohort in the Hospital Setting.","authors":"Isca Hershkowitz, Joshua Moss, Jacob Sosna, Eyal Netser, Avivit Cahn, Alon Y Hershko","doi":"","DOIUrl":"","url":null,"abstract":"Background: Management of patients with reported iodinated contrast media (ICM) allergy is not supported by sufficient data. It is assumed that these patients are at risk for severe reactions, and that premedication provides protection.Objectives: To examine current practice and prognosis in hospitalized patients with ICM allergy.Methods: In this retrospective study, we analyzed data of 17,356 patients who were hospitalized between 2018 and 2022 and referred for imaging. No-allergy and allergy groups were matched by age, sex, co-morbidities, and indications for imaging. Statistical analysis compared demographic, clinical, and imaging-related parameters.Results: Our study included records of 501 patients with ICM allergy and 16,855 with no allergy. Patients with allergy were older (70.92 ± 16.25 vs. 59.02 ± 23.74 years, P < 0.001), female preponderance (male proportion 42.5% vs. 54%, P < 0.001), and those with increased cardiovascular and metabolic co-morbidities. The rate of ICM injection was similar among patients with ICM allergy (34%) and no allergy (36%). Most patients with ICM allergy did not receive premedication. Allergic patients demonstrated increased mortality (25.9% vs. 16.5%, P < 0.001); however, this result was not associated with the diagnosis of allergy, anaphylactic reactions, or premedication.Conclusions: ICM allergy is mostly reported in patients with advanced age and multiple co-morbidities. Mortality was not increased when compared to matched non-allergic individuals. Among patients with reported allergy who were injected with ICM, anaphylaxis was not a cause of death, although fewer than half received premedication. Prospective trials are warranted to revise the clinical approach to ICM allergy.","PeriodicalId":50268,"journal":{"name":"Israel Medical Association Journal","volume":"27 1","pages":"42-48"},"PeriodicalIF":1.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143392351","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0