Israel Medical Association Journal最新文献

Post-October 7th in the Academy: Legacies of Nazism and the Resurgence of Antisemitism in Contemporary University Education. 10月7日之后的学院：纳粹主义的遗产和当代大学教育中反犹主义的复苏。

IF 1.3 4区医学

Israel Medical Association Journal Pub Date : 2025-09-01

Tessa Chelouche

引用次数: 0

Coexistence of Fabry Disease and Antiphospholipid Syndrome: A Prospective Cohort Study. 法布里病和抗磷脂综合征共存：一项前瞻性队列研究

IF 1.3 4区医学

Israel Medical Association Journal Pub Date : 2025-09-01

Hitam Hagog Natour, Izabella Elgardt, Aiman Natour, Amed Natour, Yair Levy

{"title":"Coexistence of Fabry Disease and Antiphospholipid Syndrome: A Prospective Cohort Study.","authors":"Hitam Hagog Natour, Izabella Elgardt, Aiman Natour, Amed Natour, Yair Levy","doi":"","DOIUrl":"","url":null,"abstract":"Background: Antiphospholipid syndrome (APS) is a common form of acquired thrombophilia associated with a high thrombotic risk. Fabry's disease (FD) is an X-linked lysosomal storage disease caused by mutations in the alpha-galactosidase A (GLA) gene and presents with a wide range of clinical manifestations, including a high rate of thrombosis. Previously reported, 45% of FD patients were found to have antiphospholipid autoantibodies.Objectives: To determine the prevalence of FD in patients with APS.Methods: We conducted a prospective study. Data were collected from 41 APS patients at our outpatient clinic at Meir Medical Center in Israel. We utilized chemical and genetic analyses to identify FD among APS patients. Dried blood spot (DBS) was used to assess GLA activity in males, and mutational analysis of the GLA gene was performed by sequencing exons and their flanking regions in women.Results: Among 41 antiphospholipid patients, one male patient was diagnosed with FD. Gal variants were not detected in any of the tested female patients.Conclusions: We found a low prevalence (2.4%) of FD in APS patients. Larger studies are needed to evaluate the clinical utility and cost-effectiveness of routine FD screening in this population.","PeriodicalId":50268,"journal":{"name":"Israel Medical Association Journal","volume":"27 9","pages":"567-570"},"PeriodicalIF":1.3,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145034586","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Role of Obesity in Autoimmune Disease Development. 肥胖在自身免疫性疾病发展中的作用

IF 1.3 4区医学

Israel Medical Association Journal Pub Date : 2025-09-01

Mohammad Adawi, Amin Adawi, Said Abozaid

引用次数: 0

Valvular Heart Failure as a Distinct Group in Acute Decompensated Heart Failure. 急性失代偿性心力衰竭中瓣膜性心力衰竭的独特组。

IF 1.3 4区医学

Israel Medical Association Journal Pub Date : 2025-09-01

Assi Milwidsky, Omar Saeed, Amrita Balgobind, Rachel Clark, Francesco Castagna, Shivank Madan, Yan Topilsky, Edwin C Ho, Azeem Latib, Ulrich P Jorde

{"title":"Valvular Heart Failure as a Distinct Group in Acute Decompensated Heart Failure.","authors":"Assi Milwidsky, Omar Saeed, Amrita Balgobind, Rachel Clark, Francesco Castagna, Shivank Madan, Yan Topilsky, Edwin C Ho, Azeem Latib, Ulrich P Jorde","doi":"","DOIUrl":"","url":null,"abstract":"Background: Functional mitral and tricuspid regurgitation (fMR and fTR, respectively) portend increased morbidity and mortality among heart failure (HF) patients.Objectives: To characterize acute decompensated valvular HF (VHF) as a novel HF category, defined by presence of either more than moderate fTR or more than moderate fMR with left ventricular ejection fraction (LVEF) ≤ 50%.Methods: Patients with VHF were prospectively enrolled over a 6-month period and compared to acute decompensated heart failure (ADHF) patients without significant fTR or fMR. We used a standardized diuretic protocol when indicated, and appropriate inpatient guideline-directed medical therapy was initiated.Results: Among 322 patients admitted with ADHF, 83 (26%) met VHF criteria with mean age 66 ± 13 years, 43 (52%) males, and median LVEF of 30% (20-55). Of 61 patients in whom the diuretic protocol was initiated, 59 (97%) had an adequate response (i.e., > 100 cc/hour for at least 6 hours). VHF patients had longer length of hospitalization (8 [5-13] vs. 5 [3-8] days, P < 0.001), and higher rates of 90-day heart replacement therapy (HRT) or death (hazard ratio 2.52, 95% confidence interval (1.13-5.64); P = 0.024).Conclusions: Over a quarter of ADHF patients can be newly categorized as VHF patients, distinguished by prolonged hospitalization and worse 90-day mortality / HRT rate. The initial response rate to a standardized diuretic protocol was high.","PeriodicalId":50268,"journal":{"name":"Israel Medical Association Journal","volume":"27 9","pages":"561-566"},"PeriodicalIF":1.3,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145034581","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Perioperative and Postoperative Complications During Total Laparoscopic Hysterectomy in Patients with a Previous Cesarean Section. 既往剖宫产患者腹腔镜全子宫切除术的围术期及术后并发症。

IF 1.3 4区医学

Israel Medical Association Journal Pub Date : 2025-09-01

Yuval Gedalia, Yael Baumfeld, Reut Rotem, Moran Weiss, Neriya Yohay, Adi Y Weintraub

{"title":"Perioperative and Postoperative Complications During Total Laparoscopic Hysterectomy in Patients with a Previous Cesarean Section.","authors":"Yuval Gedalia, Yael Baumfeld, Reut Rotem, Moran Weiss, Neriya Yohay, Adi Y Weintraub","doi":"","DOIUrl":"","url":null,"abstract":"Background: Cesarean section (CS) comprised almost one-third of all births. One of the complications after CS is intra-abdominal and pelvic adhesions formation.Objectives: To investigate whether a previous CS poses an additional perioperative or postoperative risk for complications when performing a total laparoscopic hysterectomy (TLH).Methods: We conducted a retrospective cohort study of women who had undergone a TLH between 2014 and 2020. Perioperative and postoperative complications were assessed according to the Clavien-Dindo classification system. Descriptive statistics were used to analyze the results.Results: In total, 190 women underwent TLH during the study period, 50 (26.5%) had a previous CS (study group) and 140 (73.5%) had no history of CS. The complication rates using the Clavien-Dindo classification system were similar in both groups; however, the major complications rate was not significantly higher in the study group (CS 6% vs. no CS 1.4%, P = 0.08). Urethral injury was the most common major complication (2, 4% vs. 1, 0.7%). The duration of surgery (125 min vs. 112 min, P = 0.02), estimated blood loss (174 ml vs. 115 ml, P = 0.02), and additional postoperative endoscopic interventions (4% vs. 0%, P = 0.01) and were significantly greater in patients with a previous CS.Conclusions: Although the need for postoperative endoscopic interventions, surgery duration, and estimated blood loss were significantly higher in patients with a previous CS, TLH remains a safe and recommended procedure for these patients. Major complications are rare and do not occur more frequently following a previous CS.","PeriodicalId":50268,"journal":{"name":"Israel Medical Association Journal","volume":"27 9","pages":"571-576"},"PeriodicalIF":1.3,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145034528","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparison of Outcomes of Chronic Obstructive Pulmonary Disease Patients Hospitalized in Hospital-at-Home vs. In-hospital Settings: A Systematic Review and Meta-analysis. 慢性阻塞性肺疾病患者在医院与在医院住院的结局比较：系统回顾和荟萃分析

IF 1.3 4区医学

Israel Medical Association Journal Pub Date : 2025-09-01

Yaron Niv

引用次数: 0

Methotrexate-induced Reversible Stroke-like Neurotoxicity. 甲氨蝶呤诱导可逆性卒中样神经毒性。

IF 1.3 4区医学

Israel Medical Association Journal Pub Date : 2025-09-01

Aaron Sulkes, Adi Pomerantz, Daniel Reinhorn, Chen Meir Kadosh, Tal Granek, Baruch Brenner

引用次数: 0

Laparoscopic Right Colectomy with Intracorporeal Anastomosis Is Associated with Lower Rate of Incisional Hernia Compared to Extracorporeal Anastomosis. 与体外吻合相比，腹腔镜右结肠切除术与体内吻合的切口疝发生率较低。

IF 1.3 4区医学

Israel Medical Association Journal Pub Date : 2025-09-01

Yehuda Hershkovitz, Chen Monfred, Igor Jeroukhimov, Amir Ben Yehuda

{"title":"Laparoscopic Right Colectomy with Intracorporeal Anastomosis Is Associated with Lower Rate of Incisional Hernia Compared to Extracorporeal Anastomosis.","authors":"Yehuda Hershkovitz, Chen Monfred, Igor Jeroukhimov, Amir Ben Yehuda","doi":"","DOIUrl":"","url":null,"abstract":"Background: Laparoscopic right hemicolectomy is considered the gold standard surgical treatment for patients with right colon malignancies. The restoration of bowel continuity can be performed by intracorporal (ICA) or extracorporal (ECA) techniques.Objectives: To evaluate a single-center experience in laparoscopic right colectomy, comparing patients with ICA and ECA.Methods: This is a case-control retrospective study included all patients who underwent laparoscopic right colectomy between the years 2016-2022 at our medical center. Patients were divided according to the operative technique. The study database included demographics as well as intraoperative and postoperative parameters.Results: Overall, 125 patients were included in the study, which included 98 patients (78.4%) from the ICA group included and 27 patients in the ECA group. Both groups were comparable in demographics and co-morbidities. No significant differences were observed between the groups in intraoperative complications, length of surgery, return to the oral diet, and length of hospital stay. The incidence of postoperative ventral hernia was significantly higher in patients from the ECA group (18.5% vs. 3.1%, P = 0.012).Conclusions: Laparoscopic right colectomy with ICA is associated with a lower rate of postoperative ventral hernias.","PeriodicalId":50268,"journal":{"name":"Israel Medical Association Journal","volume":"27 9","pages":"552-555"},"PeriodicalIF":1.3,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145034600","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Navigating Fertility Challenges: A Case Report on Immune Thrombocytopenia and Antiphospholipid Antibodies in a Woman Pursuing Pregnancy. 导航生育挑战：一个妇女追求怀孕的免疫血小板减少症和抗磷脂抗体的病例报告。

IF 1.3 4区医学

Israel Medical Association Journal Pub Date : 2025-09-01

Roy Bitan, Omri Segal, Mudi Misgav, Nancy Agmon-Levin, Raoul Orvieto, Michal Simchen, Ronit Machtinger

引用次数: 0

Concept of the Sick Bay in the Nazi Camps: Humanity or Terror. 纳粹集中营医务室的概念：人性还是恐怖。

IF 1.3 4区医学

Israel Medical Association Journal Pub Date : 2025-09-01

George M Weisz

引用次数: 0