Israel Medical Association Journal最新文献

Clinical Aspects of Postmortem Sperm Procurement: What Do We Actually Know?

IF 1.8 4区医学

Israel Medical Association Journal Pub Date : 2025-04-01

Shevach Friedler, Bozhena Saar-Ryss, Myriam Safrai

引用次数: 0

Mortality and Readmissions of Solid-Organs Transplant Recipients Hospitalized Due to COVID-19 Infection with the Omicron Variant: A Matched Cohort Study.

IF 1.8 4区医学

Israel Medical Association Journal Pub Date : 2025-04-01

Daniella Vronsky, Genady Drozdinsky, Irit Ayalon-Dangur, Ya'ara Leibovici Weissman, Noa Eliakim-Raz

{"title":"Mortality and Readmissions of Solid-Organs Transplant Recipients Hospitalized Due to COVID-19 Infection with the Omicron Variant: A Matched Cohort Study.","authors":"Daniella Vronsky, Genady Drozdinsky, Irit Ayalon-Dangur, Ya'ara Leibovici Weissman, Noa Eliakim-Raz","doi":"","DOIUrl":"","url":null,"abstract":"Background: Solid organ transplant (SOT) recipients represent a particularly vulnerable group due to their reliance on immunosuppressive therapies. Previous studies indicated a mortality rate of 20%-30% among SOT recipients with coronavirus disease 2019 (COVID-19). With the advent of the Omicron variant in November 2021, characterized by milder symptoms and lower mortality rates in the general population, safety measures relaxed, potentially impacting vulnerable populations like SOT recipients.Objectives: To investigate mortality and morbidity among hospitalized SOT recipients with COVID-19 infection during the Omicron wave.Methods: A retrospective, propensity-matched cohort study conducted at the Rabin Medical Center, Israel, spanned from November 2021 to June 2023. Adult SOT recipients hospitalized with COVID-19 were compared to matched controls.Results: Among 139 hospitalized SOT recipients and 209 controls, SOT recipients hospitalized with COVID-19 displayed higher in-hospital mortality (19% vs. 11%) and 90-day all-cause mortality (30% vs. 17%). In addition, the 90-day readmission rate was significantly higher among SOT recipients (43% vs. 31%). Multivariable analysis confirmed these trends, with SOT recipients exhibiting increased risk for mortality, readmission, invasive ventilation, and intensive care unit admission.Conclusions: The heightened vulnerability of hospitalized SOT recipients during the Omicron wave was characterized by higher mortality and readmission rates compared to matched controls. Despite the perceived milder nature of the Omicron variant, SOT recipients remain disproportionately affected. Continued vigilance and targeted interventions are necessary for this population including vaccinations and adherence to preventive measures. Investigating this population's outcomes through the changing COVID-19 variants is still warranted.","PeriodicalId":50268,"journal":{"name":"Israel Medical Association Journal","volume":"27 4","pages":"216-220"},"PeriodicalIF":1.8,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143797104","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Walking the Pathogenic Tightrope: Is Mycobacterium simiae a Benign Colonizer or a Potential Threat in Crohn's Disease? 走在致病的钢丝上：分枝杆菌是克罗恩病的良性定植菌还是潜在威胁？

IF 1.8 4区医学

Israel Medical Association Journal Pub Date : 2025-04-01

Einat Savin, Kassem Sharif, Sharon Amit, Shomron Ben Horin

引用次数: 0

Neutrophil-to-Lymphocyte Ratio, C-Reactive Protein, and Mean Platelet Volume in Differentiation of Ascites Causes.

IF 1.8 4区医学

Israel Medical Association Journal Pub Date : 2025-04-01

Raymond Farah, Tammy Jacoby, Rola Khamisy-Farah

{"title":"Neutrophil-to-Lymphocyte Ratio, C-Reactive Protein, and Mean Platelet Volume in Differentiation of Ascites Causes.","authors":"Raymond Farah, Tammy Jacoby, Rola Khamisy-Farah","doi":"","DOIUrl":"","url":null,"abstract":"Background: Ascites is a product of fluid accumulation within the peritoneal cavity. Underlying etiologies include cirrhosis, congestive heart failure (CHF), nephrotic syndrome, and malignancies. Patients with cirrhotic ascites are at increased risk for infections, especially spontaneous bacterial peritonitis (SBP), which is associated with high rates of morbidity and mortality. Ascites is diagnosed both clinically and sonographically. SBP is diagnosed via abdominal paracentesis, a relatively safe and effective procedure. However, abdominal paracentesis carries risks such as bleeding, bowel perforation, and infection.Objectives: To identify new inflammatory markers as alternative or replacement methods for accurately evaluating patients before and after abdominal paracentesis and how these new inflammatory markers can be evaluated from a simple, inexpensive, and routinely performed blood sample.Methods: A total of 106 patients admitted with ascites were classified into three groups based on the underlying etiology of their condition: malignant ascites (30 patients), ascites secondary to CHF (30 patients), and ascites secondary to cirrhosis (46 patients). Levels of neutrophil-lymphocyte ratio (NLR), mean platelet volume, and C-reactive protein among the study groups were examined through blood samples and subsequently compared.Results: NLR values within malignant ascites and CHF ascites were significantly higher than cirrhotic ascites (P = 0.002). In addition, among risk factors for developing ascites, significant correlations were found among the three groups in hypertension (P < 0.001), diabetes mellitus (P = 0.003), hyperlipidemia (P = 0.002), CHF (P < 0.001), and ischemic heart disease (P < 0.001) variables.Conclusions: NLR may be a prognostic tool in patient evaluation of ascites.","PeriodicalId":50268,"journal":{"name":"Israel Medical Association Journal","volume":"27 4","pages":"211-215"},"PeriodicalIF":1.8,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143797106","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Analysis of 498 Pedestrian Injuries Involving Bicycles, E-bicycles, and E-scooters: Characteristics and Factors Influencing Injury Severity.

IF 1.8 4区医学

Israel Medical Association Journal Pub Date : 2025-04-01

Ron Gurel, Rashad Seh, Mohamed Abadi, Shai Factor, Adnan Abdellatif, Addy S Brandstetter, Yair Neuman, Amal Khoury

{"title":"Analysis of 498 Pedestrian Injuries Involving Bicycles, E-bicycles, and E-scooters: Characteristics and Factors Influencing Injury Severity.","authors":"Ron Gurel, Rashad Seh, Mohamed Abadi, Shai Factor, Adnan Abdellatif, Addy S Brandstetter, Yair Neuman, Amal Khoury","doi":"","DOIUrl":"","url":null,"abstract":"Background: The increasing use of micromobility solutions (MMS), including electric scooters, electric, and non-motorized bicycles, has revolutionized urban transportation. We addressed the rising incidence of injuries related to pedestrian-MMS accidents, with a specific focus on pedestrian injuries.Objectives: To improve clinician comprehension of patient characteristics and injuries associated with pedestrian-MMS accidents and to provide insights for injury prevention, policy making, and urban planning.Methods: We conducted a retrospective analysis, June 2017 to January 2023, of pedestrians who were admitted to the emergency department post-MMS accidents. Data included patient characteristics, type of MMS, time of the accident, and outcome variables including type of injury, hospitalization, and surgical treatment.Results: The study cohort included 498 pedestrians (57.7% women), with a mean age of 42.3 ± 21.8 years. Nighttime accidents were 53.2% of cases. Fractures were the dominant type of injury (18.3% of the total cohort). Age, particularly those ≥ 60 years, significantly (P < 0.05) influenced fracture, hospitalization, and surgery rates (30.6%, 22.4%, and 12.6%, respectively). The odds ratio of having a fracture for pedestrians ≥ 60 years was 5.35 (P = 0.008). Interestingly, the type of MMS did not significantly affect outcomes.Conclusions: Age emerged as a critical factor in injury severity, emphasizing the need for age-specific safety measures in urban environments. The type of MMS did not show a significant influence on outcomes, emphasizing the importance of a comprehensive regulation of all MMS types. The high rate of accidents during nighttime calls for focused interventions during this period to prevent accidents.","PeriodicalId":50268,"journal":{"name":"Israel Medical Association Journal","volume":"27 4","pages":"244-248"},"PeriodicalIF":1.8,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143797040","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparison in Therapeutic Outcome of Ultrasound-guided Botulinum Injections for Limb Spasticity Versus Dystonia.

IF 1.8 4区医学

Israel Medical Association Journal Pub Date : 2025-04-01

Gilad Yahalom, Mikhal E Cohen, Ilana Israel, Roni Eichel, Yosef Shechter

{"title":"Comparison in Therapeutic Outcome of Ultrasound-guided Botulinum Injections for Limb Spasticity Versus Dystonia.","authors":"Gilad Yahalom, Mikhal E Cohen, Ilana Israel, Roni Eichel, Yosef Shechter","doi":"","DOIUrl":"","url":null,"abstract":"Background: Botulinum toxin (BT) can alleviate limb dystonia, but limited insurance coverage hinders its utilization.Objectives: To compare the therapeutic efficacy of BT injections for spasticity and dystonia of the limbs.Methods: BT injections of hypertonic limbs were administered under ultrasound guidance between 2019 and 2024 for either limb dystonia or limb spasticity.Results: Of 74 patients included, 57 were diagnosed with spasticity and 17 with dystonia. In total, 276 therapeutic cycles were administered. The dropout rates were 45.6% in the spasticity group and 41.2% in the dystonia group (P = 0.48). There was no significant difference in subjective motor improvement between dystonia and spasticity (P = 0.16). Dystonia patients reported significantly better pain relief (98.5 ± 4.9% vs. 72.4 ± 35.6% respectively, P < 0.001). Notably, 74.3% of dystonia treatments reported moderate or marked improvement, whereas only 54.0% of spasticity treatments did (P > 0.05), based on patient the global impression of change (PGI-C) scale. Side effects were infrequent.Conclusions: BT injections for limb spasticity and dystonia are partially effective. Nonetheless, the dropout rate is high. While BT injections are more effective in relieving pain for dystonia compared to spasticity, disease severity gradually improves over time in treated patients with spasticity but not with dystonia.","PeriodicalId":50268,"journal":{"name":"Israel Medical Association Journal","volume":"27 4","pages":"238-243"},"PeriodicalIF":1.8,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143797047","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Minocycline-induced Polyarteritis Nodosa Manifesting as Tenosynovitis, Edema, and Rash: A Case Report.

IF 1.8 4区医学

Israel Medical Association Journal Pub Date : 2025-04-01

Roni Meidan, Dror Lahav, Iris Eshed, Katya Meridor, Ori Elkayam, Ofir Elalouf

引用次数: 0

Surgery in Auschwitz: Therapy or Experience?

IF 1.8 4区医学

Israel Medical Association Journal Pub Date : 2025-04-01

George M Weisz

引用次数: 0

Infant Botulism in Israel: A Rare Disease That Still Exist.

IF 1.8 4区医学

Israel Medical Association Journal Pub Date : 2025-04-01

Uri Rubinstein, Nechama Sharon, Ahmad Masarwa, Michael Benacon, Elka Bella Kosinovski

引用次数: 0

Outcomes of Percutaneous Cholecystostomy in Older Adults with Acute Cholecystitis.

IF 1.8 4区医学

Israel Medical Association Journal Pub Date : 2025-04-01

Edden Slomowitz, Lisa Cooper, Hadas Tsivion-Visbord, Tzippy Shochat, Hanoch Kashtan, Ilan Schrier

{"title":"Outcomes of Percutaneous Cholecystostomy in Older Adults with Acute Cholecystitis.","authors":"Edden Slomowitz, Lisa Cooper, Hadas Tsivion-Visbord, Tzippy Shochat, Hanoch Kashtan, Ilan Schrier","doi":"","DOIUrl":"","url":null,"abstract":"Background: Acute cholecystitis (ACC) is one of the most common diagnoses encountered in surgical wards. A number of treatment modalities are available, and various guidelines have been developed to help decision making. Many factors influence treatment strategies, including patient age and frailty. Due to the increasing proportion of older patients, consideration into the best treatment modalities for this population are warranted.Objectives: To determine outcomes of elderly patients with ACC according to different treatment strategies.Methods: A retrospective analysis of consecutive patients aged ≥ 80 years who were admitted with a diagnosis of ACC between 2015 and 2019 to a single academic center. Patients were divided into three groups according to treatment: percutaneous cholecystostomy tube placement, cholecystectomy, intravenous antibiotic treatment only.Results: Overall, 466 patients were included in the cohort. The majority (approximately 75%) were treated with antibiotics only, 17% underwent percutaneous cholecystostomy, and 8% underwent laparoscopic cholecystectomy. One-year mortality was 28.1%. The highest mortality rate was 41.6% in the cholecystostomy group (P = 0.002). In multivariable analysis age, functional status, C-reactive protein, and albumin levels were found to be independent risk factors for 1-year mortality (hazard ratio [HR] 1.08, 0.56, 0.98, 0.4, respectively). Cholecystostomy increased risk of one-year mortality compared to cholecystectomy and antibiotics alone (HR 0.61, 0.23, respectively).Conclusions: The use of cholecystostomy for ACC in older adults is an independent risk factor for 1-year mortality. Its use in older adults should be reserved for carefully selected cases.","PeriodicalId":50268,"journal":{"name":"Israel Medical Association Journal","volume":"27 4","pages":"249-254"},"PeriodicalIF":1.8,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143797107","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0