{"title":"Surgery in Auschwitz: Therapy or Experience?","authors":"George M Weisz","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":50268,"journal":{"name":"Israel Medical Association Journal","volume":"27 4","pages":"207-210"},"PeriodicalIF":1.8,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143796266","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Minocycline-induced Polyarteritis Nodosa Manifesting as Tenosynovitis, Edema, and Rash: A Case Report.","authors":"Roni Meidan, Dror Lahav, Iris Eshed, Katya Meridor, Ori Elkayam, Ofir Elalouf","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":50268,"journal":{"name":"Israel Medical Association Journal","volume":"27 4","pages":"255-257"},"PeriodicalIF":1.8,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143797103","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Uri Rubinstein, Nechama Sharon, Ahmad Masarwa, Michael Benacon, Elka Bella Kosinovski
{"title":"Infant Botulism in Israel: A Rare Disease That Still Exist.","authors":"Uri Rubinstein, Nechama Sharon, Ahmad Masarwa, Michael Benacon, Elka Bella Kosinovski","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":50268,"journal":{"name":"Israel Medical Association Journal","volume":"27 4","pages":"229-230"},"PeriodicalIF":1.8,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143797102","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Edden Slomowitz, Lisa Cooper, Hadas Tsivion-Visbord, Tzippy Shochat, Hanoch Kashtan, Ilan Schrier
{"title":"Outcomes of Percutaneous Cholecystostomy in Older Adults with Acute Cholecystitis.","authors":"Edden Slomowitz, Lisa Cooper, Hadas Tsivion-Visbord, Tzippy Shochat, Hanoch Kashtan, Ilan Schrier","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>Acute cholecystitis (ACC) is one of the most common diagnoses encountered in surgical wards. A number of treatment modalities are available, and various guidelines have been developed to help decision making. Many factors influence treatment strategies, including patient age and frailty. Due to the increasing proportion of older patients, consideration into the best treatment modalities for this population are warranted.</p><p><strong>Objectives: </strong>To determine outcomes of elderly patients with ACC according to different treatment strategies.</p><p><strong>Methods: </strong>A retrospective analysis of consecutive patients aged ≥ 80 years who were admitted with a diagnosis of ACC between 2015 and 2019 to a single academic center. Patients were divided into three groups according to treatment: percutaneous cholecystostomy tube placement, cholecystectomy, intravenous antibiotic treatment only.</p><p><strong>Results: </strong>Overall, 466 patients were included in the cohort. The majority (approximately 75%) were treated with antibiotics only, 17% underwent percutaneous cholecystostomy, and 8% underwent laparoscopic cholecystectomy. One-year mortality was 28.1%. The highest mortality rate was 41.6% in the cholecystostomy group (P = 0.002). In multivariable analysis age, functional status, C-reactive protein, and albumin levels were found to be independent risk factors for 1-year mortality (hazard ratio [HR] 1.08, 0.56, 0.98, 0.4, respectively). Cholecystostomy increased risk of one-year mortality compared to cholecystectomy and antibiotics alone (HR 0.61, 0.23, respectively).</p><p><strong>Conclusions: </strong>The use of cholecystostomy for ACC in older adults is an independent risk factor for 1-year mortality. Its use in older adults should be reserved for carefully selected cases.</p>","PeriodicalId":50268,"journal":{"name":"Israel Medical Association Journal","volume":"27 4","pages":"249-254"},"PeriodicalIF":1.8,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143797107","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Majd Said, Yossy Machluf, Vladimir Banchenko, Eduardo Cohen, Yoram Chaiter
{"title":"Nail-patella Syndrome and Bilateral Nephrolithiasis: Rare Case Study of a 17-year-old Israeli Male.","authors":"Majd Said, Yossy Machluf, Vladimir Banchenko, Eduardo Cohen, Yoram Chaiter","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":50268,"journal":{"name":"Israel Medical Association Journal","volume":"27 4","pages":"258-261"},"PeriodicalIF":1.8,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143797105","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Impact of the COVID-19 Pandemic on Seasonal Enteroviral Meningitis in Hospitalized Children.","authors":"Evgenia Gurevich, Mahdi Seh, Yaser Nabari, Vered Shkalim Zemer","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>Enterovirus meningitis (EM) is a common central nervous system (CNS) infection with a seasonal peak in summer and fall.</p><p><strong>Objectives: </strong>To describe the epidemiologic and clinical patterns of EM in children before (2017-2019 years) and during the coronavirus disease 2019 (COVID-19) pandemic (2020-2022).</p><p><strong>Methods: </strong>This retrospective study included children (age 0-16 years) hospitalized in a pediatric department in Israel diagnosed with EM: January 2017-December 2019 and January 2020-December 2022. The seasonal peak for each period was defined as the maximal incidence in particular months. EM was diagnosed by reverse transcription polymerase chain reaction of cerebrospinal fluid (CSF) for enteroviruses.</p><p><strong>Results: </strong>During the study period, EM was diagnosed in 134 cases (median age 5 months [1-51], 76 [57%] males); 72 during 2017-2019 and 62 during 2020-2022. The most common presentation was fever. C-reactive protein (CRP) was elevated in 57 cases (43%). CSF profile showed pleocytosis in 130 cases (97%) and elevated protein in 80 (60%). In the 2020-2022 group, fewer patients were febrile, CRP was higher, and CSF profile showed a higher glucose level compared to the 2017-2019 group. Seasonal peaks in 2017-2019 occurred June-August, and in 2020-2022 February-April.</p><p><strong>Conclusions: </strong>The COVID-19 pandemic altered the clinical characteristics of EM and its seasonal peak. Clinicians should be aware of changes in epidemiological patterns of EM to make appropriate diagnoses in viral infection in order to avoid unnecessary antibiotic treatment.</p>","PeriodicalId":50268,"journal":{"name":"Israel Medical Association Journal","volume":"27 4","pages":"224-228"},"PeriodicalIF":1.8,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143796280","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Adey Matani, Nechama Sharon, Niv Reiss, Moshe Yana, Roxana Cleper, Achiya Z Amir
{"title":"Hyponatremia in Pediatric Community-acquired Pneumonia is Associated with Bacterial Etiology and Severity Markers.","authors":"Adey Matani, Nechama Sharon, Niv Reiss, Moshe Yana, Roxana Cleper, Achiya Z Amir","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>Hyponatremia is common among hospitalized children, including those with community acquired pneumonia. The prevalence and severity of hyponatremia were reported to correlate with disease. However, data regarding the association between hyponatremia and causative infectious pathogens are limited and results are inconsistent.</p><p><strong>Objectives: </strong>To investigate the associations between sodium levels, severity and causative pathogen in children with pneumonia.</p><p><strong>Methods: </strong>A retrospective study of all children (< 18 years) hospitalized with pneumonia from 1 January 2018 to 31 December 2020. Admission sodium levels were compared to the presumed etiological pathogens, clinical parameters, and inflammatory markers.</p><p><strong>Results: </strong>Among 751 (52% males) children, 10 (1%) had sodium levels < 130 mEq/L, 187 (25%) had mildly decreased levels 130-134 mEq/L, and the remaining 554 (74%) had normal levels 135-145 mEq/L. Sodium levels < 130 mEq/L were found in 7/236 (3%) of the patients with presumed bacterial pneumonia, in 0/20 of patients with presumed atypical-bacterial, and in only 3/495 (0.6%) of the patients with a presumed viral infection, P < 0.001. Sodium levels < 135 mEq/L conferred an odds ratio of 3.1 (95% confidence interval [95%CI] 2.1-4.3) and levels < 130 mEq/L an odds ratio of 6.8 (95%CI 1.8-33.0) for bacterial infection, P < 0.001 for both. Hyponatremia was also inversely associated with high white blood cell counts, absolute neutrophil cell counts, and C-reactive protein levels.</p><p><strong>Conclusions: </strong>Hyponatremia was common among children hospitalized with pneumonia and was associated with elevated inflammatory markers and presumed bacterial pneumonia.</p>","PeriodicalId":50268,"journal":{"name":"Israel Medical Association Journal","volume":"27 4","pages":"231-237"},"PeriodicalIF":1.8,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143797066","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Rare Cause of Respiratory Distress in a 1-month-old Infant.","authors":"Gavriel Hain, Micha Aviram, Aviva Levitas, Hana Krymko, Aviv Goldbart, Inbal Golan-Tripto","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":50268,"journal":{"name":"Israel Medical Association Journal","volume":"27 3","pages":"177-179"},"PeriodicalIF":1.8,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143712007","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mai Shiber, Nadav Shalev, Maor Leibzon, Nechama Sharon
{"title":"An 11-Year-Old Patient with Anorexia Nervosa Presenting with Severe Clinical and Laboratory Deterioration: A Case Report.","authors":"Mai Shiber, Nadav Shalev, Maor Leibzon, Nechama Sharon","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":50268,"journal":{"name":"Israel Medical Association Journal","volume":"27 3","pages":"180-182"},"PeriodicalIF":1.8,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143712025","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Shoshana Revel-Vilk, Ari Zimran, Aya Abramov, David Strich
{"title":"Short Stature as a Diagnostic Indicator for Children with Gaucher Disease.","authors":"Shoshana Revel-Vilk, Ari Zimran, Aya Abramov, David Strich","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":50268,"journal":{"name":"Israel Medical Association Journal","volume":"27 3","pages":"196-200"},"PeriodicalIF":1.8,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143712031","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}