Elizabeth Benge, Julie C Lauffenburger, Michelle Reid, Rebecca Rottapel, Darshan Mehta, Suzanne M Bertisch
{"title":"Leveraging digital therapeutics to improve physician sleep: a pilot implementation study.","authors":"Elizabeth Benge, Julie C Lauffenburger, Michelle Reid, Rebecca Rottapel, Darshan Mehta, Suzanne M Bertisch","doi":"10.5664/jcsm.11666","DOIUrl":"https://doi.org/10.5664/jcsm.11666","url":null,"abstract":"<p><p>Given the high prevalence of physician burnout, strategies are needed to improve physician mental health and well-being. As sleep disturbance predicts burnout, there is a need to evaluate evidence-based, potentially scalable treatments that target physician sleep and sleep-related health. This pilot implementation study enrolled physicians and gave them access to the Sleep Healthy Using the Internet (SHUT-i), a six-session self-guided Cognitive Behavioral Therapy for Insomnia (CBTi) treatment program. Among 34 consented physicians, 44.1% engaged at least once with the platform. Among those, 23.5% completed all six sessions. Among the eight completers, the program's session length, time requirements, and ease of access received high satisfaction ratings, and 75% reported they would recommend the program to other clinicians. In exploring effectiveness, SHUT-i was associated with reductions in insomnia severity, sleep disturbance, and sleep-related impairment post-intervention. This pilot study demonstrates the promise of an evidence-based, web-based CBTi program for improving insomnia among physicians.</p><p><strong>Clinical trial registration: </strong>Registry: ClinicalTrials.gov; Identifier: NCT05289596.</p>","PeriodicalId":50233,"journal":{"name":"Journal of Clinical Sleep Medicine","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143671720","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Onyekachi S Ezeokeke, Janelle M Fine, Jennifer L Martin, Prerna Gupta, Atul Malhotra, Melissa P Knauert, Erica B Feldman, Biren B Kamdar
{"title":"An approach to improving efficiency of actigraphy data in research: use of statistical software to facilitate batch import.","authors":"Onyekachi S Ezeokeke, Janelle M Fine, Jennifer L Martin, Prerna Gupta, Atul Malhotra, Melissa P Knauert, Erica B Feldman, Biren B Kamdar","doi":"10.5664/jcsm.11612","DOIUrl":"10.5664/jcsm.11612","url":null,"abstract":"<p><p>Despite the recent discontinuation of Philips Actiwatch devices, volumes of actigraphy data remain unanalyzed, and these and similar devices continue to be used for clinical and research applications. In this report, we present a Stata \"do\" file that automates the process of importing and appending raw data files downloaded from Philips Actiware software. For example, in less than 60 seconds, our do file imported, appended, and cleaned 189,596 epochs of data from raw 48-hour actigraphy data files of 35 critically ill patients, yielding a single unified dataset with usable variables ready for analysis. Portable and scalable, this approach can facilitate error-free generation of single- or multi-day actigraphy datasets from an unlimited number of patients. Although designed for Stata, this simple executable file can be adapted for other data platforms and applied to new and existing actigraphy data files and modified as needed for other actigraphy-based efforts.</p>","PeriodicalId":50233,"journal":{"name":"Journal of Clinical Sleep Medicine","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143665274","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Allan J Kember, Noa Gilad, Jerry Coleman, Jane Warland, Sebastian R Hobson
{"title":"A new frontier for positional therapy: obstetrics.","authors":"Allan J Kember, Noa Gilad, Jerry Coleman, Jane Warland, Sebastian R Hobson","doi":"10.5664/jcsm.11616","DOIUrl":"https://doi.org/10.5664/jcsm.11616","url":null,"abstract":"","PeriodicalId":50233,"journal":{"name":"Journal of Clinical Sleep Medicine","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143665273","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Correlation of sleep-disordered breathing with anemia and microcytosis in premenopausal women: the Nagahama study.","authors":"Kimihiko Murase, Takeshi Matsumoto, Yasuharu Tabara, Miho Egawa, Takuma Minami, Osamu Kanai, Naomi Takahashi, Satoshi Hamada, Hironobu Sunadome, Jumpei Togawa, Takuma Ohsuga, Tomoko Wakamura, Naoko Komenami, Kazuya Setoh, Takahisa Kawaguchi, Takeo Nakayama, Susumu Sato, Masaki Mandai, Toyohiro Hirai, Fumihiko Matsuda, Kazuo Chin","doi":"10.5664/jcsm.11618","DOIUrl":"https://doi.org/10.5664/jcsm.11618","url":null,"abstract":"<p><strong>Study objectives: </strong>While nocturnal hypoxia caused by sleep-disordered breathing (SDB) can result in polycythemia, the association between erythrocyte values and SDB may vary by sex and menopausal status. This study aimed to evaluate the correlation of erythrocyte variables with SDB in a large cohort categorized by sex and menopausal status from the general population.</p><p><strong>Methods: </strong>Sleep duration and SDB were assessed in community residents using a wearable actigraph and pulse oximeter. The Actigraph-adjusted 3% oxygen saturation index (Acti-3% ODI) was calculated by correcting the time measured by the pulse oximeter for sleep duration computed by the actigraph. SDB severity was defined by Acti-3% ODI as normal (<5 events/h), mild (5 to <15 events/h), and moderate to severe (≥15 events/h).</p><p><strong>Results: </strong>Data were obtained from 6,836 participants (premenopausal women, 1,580; postmenopausal women, 3,058; and men, 2,198). Multivariate analysis revealed that Acti-3%ODI was negatively correlated with hemoglobin (Hb) level in premenopausal women (β= -0.13, p < 0.01), but no significant correlations were found in postmenopausal women and men. In addition, the presence of SDB was a risk factor for microcytic anemia (Hb < 12 g/dl and Mean corpuscular volume < 80 fl) in premenopausal women (odds ratio and 95% confidence interval: mild SDB, 1.93 (1.31-2.84), p < 0.01; moderate to severe SDB, 9.02 (3.02-26.88), p < 0.01).</p><p><strong>Conclusions: </strong>SDB was associated with microcytic anemia in premenopausal women. When SDB is diagnosed in a premenopausal woman, we may need to evaluate her erythrocytic parameters.</p>","PeriodicalId":50233,"journal":{"name":"Journal of Clinical Sleep Medicine","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143665237","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Chee Weng Yong, Bernadette Quah, Juliana Tereza Colpani, Frank Kong Fei Lee, Eugene Eu-Min Loh, Raymond Chung Wen Wong
{"title":"Effectiveness of mandibular advancement devices in obstructive sleep apnea therapy for East Asian patients: a systematic review and meta-analysis.","authors":"Chee Weng Yong, Bernadette Quah, Juliana Tereza Colpani, Frank Kong Fei Lee, Eugene Eu-Min Loh, Raymond Chung Wen Wong","doi":"10.5664/jcsm.11626","DOIUrl":"https://doi.org/10.5664/jcsm.11626","url":null,"abstract":"<p><p>Prior studies have shown that a mandibular advancement device (MAD) is an effective nonsurgical treatment for obstructive sleep apnea (OSA). Most studies were performed in primarily White populations. However, East Asians have restrictive craniofacial features, such as a reduced cranial base, maxilla, and retropalatal space, which may affect their response to treatment. The objective of this study was to systematically review the use of MAD in East Asian patients and determine the effectiveness of MAD in this population. The PubMed, Embase, Scopus, CINAHL, Web of Science, and Cochrane Library databases were searched up to January 15, 2024. Studies that investigated the effects of MAD on the apnea-hypopnea index (AHI), oxygen saturation, blood pressure, and Epworth sleepiness scale (ESS) score, specifically for East Asian patients, were included. PRISMA guidelines were followed for data extraction. Twelve studies with 382 patients were included. The pooled mean reduction in AHI was 19.1 (95% CI -23.9;-14.3,<i>I<sup>2</sup></i> = 91%). The improvements in the minimal and mean oxygen saturation were 6.0% (95% CI 4.4, 7.5,<i>I<sup>2</sup></i> = 28%) and 1.2% (95% CI -0.2;2.6),<i>I<sup>2</sup></i> = 92%), respectively. Oxygen Desaturation Index was also reduced by 13.6 (3 studies, 95% CI 23.9;-3.3,<i>I<sup>2</sup></i> = 92%). Systolic and diastolic pressure changes were modest at -4.4 (9% CI -11.3;2.4,<i>I<sup>2</sup></i> = 88%) and -3.3 (95% CI = -6.3;-0.3,<i>I<sup>2</sup></i> = 55%), respectively. ESS Score had a reduction of 2.0 (95% CI= -3.3;-0.7,<i>I<sup>2</sup></i> =66%). MAD is an effective device for the management of East Asian patients with OSA. Although treatment success is expected in most patients, complete resolution is unlikely. (253 words).</p>","PeriodicalId":50233,"journal":{"name":"Journal of Clinical Sleep Medicine","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143665240","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Elizabeth Montesano, Maria E Garcia, Shannon Lyon, Jennifer Worhach, Grace Wang, Bo Zhang, Joshua August, Kiran Maski
{"title":"Rising pressure to understand the risks of hypertension in children with narcolepsy type 1.","authors":"Elizabeth Montesano, Maria E Garcia, Shannon Lyon, Jennifer Worhach, Grace Wang, Bo Zhang, Joshua August, Kiran Maski","doi":"10.5664/jcsm.11628","DOIUrl":"https://doi.org/10.5664/jcsm.11628","url":null,"abstract":"<p><strong>Study objectives: </strong>Most children/adolescents with narcolepsy type 1 (NT1) are treated with stimulants or modafinil, yet the cardiovascular effects of these medications have not been investigated in this population. We compared vital signs in youth with NT1 before and after exposure to stimulants/modafinil to test the hypotheses that these medications increase rates of elevated blood pressure (BP) and hypertension (HTN) and that body mass index (BMI) influences these outcomes.</p><p><strong>Methods: </strong>In this retrospective study, we collected electronic medical data including vital signs and polysomnography/multiple sleep latency test (PSG/MSLT) results from 39 youth with NT1 aged 7-18 at three points over 20-month period: baseline (drug-naïve/weaned), after initiating treatment, and after treatment optimization. We performed stepwise regression to determine predictors of baseline elevated BP/HTN. We used McNemar's test and generalized estimating equations to assess the effects of stimulant/modafinil exposure on vital signs.</p><p><strong>Results: </strong>The prevalence of elevated BP/HTN at baseline was 51% in our cohort and increased 21% from baseline to the final visit (p = .03). Systolic BP increased significantly with stimulant/modafinil exposure (p <0.05), while diastolic BP and heart rate (HR) showed non-significant increases. BMI was associated with increased systolic BP and HR across the three time points but not at baseline.</p><p><strong>Conclusions: </strong>Youth with NT1 are at risk for elevated BP/HTN, particularly after stimulant/modafinil treatment. We recommend revising clinical guidelines to address this risk and advocate for controlled studies to better understand the cardiovascular risks and implications of these treatments in pediatric NT1.</p>","PeriodicalId":50233,"journal":{"name":"Journal of Clinical Sleep Medicine","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143659326","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"REM-related obstructive sleep apnea: is it still an enigma or do we even care?","authors":"Gautam Ganguly","doi":"10.5664/jcsm.11672","DOIUrl":"https://doi.org/10.5664/jcsm.11672","url":null,"abstract":"","PeriodicalId":50233,"journal":{"name":"Journal of Clinical Sleep Medicine","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143651697","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Seeing the random forest for the Zzz's: machine learning's new role in sleep science.","authors":"Dustin Anderson-Bell, Brian W Locke","doi":"10.5664/jcsm.11674","DOIUrl":"https://doi.org/10.5664/jcsm.11674","url":null,"abstract":"","PeriodicalId":50233,"journal":{"name":"Journal of Clinical Sleep Medicine","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143651704","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Raman K Malhotra, Thomas M Heffron, Ilene M Rosen, Stuart F Quan, Clete A Kushida, Lawrence J Epstein
{"title":"Sleep and dreams: how the American Academy of Sleep Medicine and its members have shaped the future of the sleep field for 50 years.","authors":"Raman K Malhotra, Thomas M Heffron, Ilene M Rosen, Stuart F Quan, Clete A Kushida, Lawrence J Epstein","doi":"10.5664/jcsm.11660","DOIUrl":"https://doi.org/10.5664/jcsm.11660","url":null,"abstract":"<p><p>Over the past century, sleep has transitioned from the domain of artists, poets, and philosophers to the realm of scientists and clinicians. In the 20th century, pioneering sleep researchers and clinicians advanced their respective fields by forming organizations such as the American Academy of Sleep Medicine (AASM). For 50 years, the AASM has played a leading role in creating and shaping the field of sleep medicine, leveraging the multi-disciplinary expertise of its members to forge a new medical specialty. The organization emerged from a meeting in 1975, where academics whose research focused on sleep gathered to evaluate the necessity of establishing a new professional society to represent the nascent sleep disorders centers that were beginning to open across the country. The formation of the AASM was led by Dr. William Dement and other pioneers who played crucial roles in establishing the field through the clinical application of sleep research. Through the AASM, they created the building blocks of a medical specialty by developing accreditation and certification programs, diagnostic classifications, clinical practice guidelines, clinical training programs, peer-reviewed scientific journals, and a clinical and scientific meeting. Their persistent efforts eventually secured for the sleep medicine specialty both national recognition and broad acceptance within the medical community. Today, the field of sleep medicine remains strong as sleep physicians and other members of the clinical sleep team provide high-quality, comprehensive care for patients who have sleep and circadian disorders. Built on this solid foundation, the AASM and its members will continue to shape the future of sleep medicine.</p>","PeriodicalId":50233,"journal":{"name":"Journal of Clinical Sleep Medicine","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143617756","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}