Journal of Evolutionary Biology最新文献_第9页

Experimental tests on the evolution of sex and recombination and their adaptive significance. 性别和重组进化的实验检验及其适应性意义。

IF 2.3 3区生物学

Journal of Evolutionary Biology Pub Date : 2025-08-02 DOI: 10.1093/jeb/voaf028

Tom Parée, Henrique Teotónio

{"title":"Experimental tests on the evolution of sex and recombination and their adaptive significance.","authors":"Tom Parée, Henrique Teotónio","doi":"10.1093/jeb/voaf028","DOIUrl":"10.1093/jeb/voaf028","url":null,"abstract":"Sex and recombination generate genetic variation and facilitate adaptation by reducing selective interference, but they can also disrupt allelic combinations maintained by selection. We here review experimental evolution studies on the adaptive significance of sex and recombination in constant environments, emphasizing insights gained from population genomic data. We discuss evidence showing how meiotic segregation (sex) and crossing-over (recombination) disrupt negative disequilibrium between alleles within and between loci and as a consequence increase the fitness variance of populations and enhance selection efficacy. While sexual reproduction can facilitate adaptation when compared with asexual reproduction, the advantages of high rates of sex and recombination under facultative sexual reproduction or facultative outcrossing and self-fertilization are less clear, especially when overdominance and epistasis cause segregation and recombination loads. We further discuss the challenges of measuring interference between selected alleles, particularly under polygenic adaptation and segregation of multiple modifiers of recombination, and propose directions for future research. Our discussion underscores the nuanced role of sex and recombination in adaptation, shaped by a balance between increased genetic variation and the disruption of beneficial allele combinations.","PeriodicalId":50198,"journal":{"name":"Journal of Evolutionary Biology","volume":" ","pages":"798-810"},"PeriodicalIF":2.3,"publicationDate":"2025-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144052071","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The joint evolution of separate sexes and sexual dimorphism. 两性分离和性二态的共同进化。

IF 2.3 3区生物学

Journal of Evolutionary Biology Pub Date : 2025-08-02 DOI: 10.1093/jeb/voae136

Thomas Lesaffre, John R Pannell, Charles Mullon

{"title":"The joint evolution of separate sexes and sexual dimorphism.","authors":"Thomas Lesaffre, John R Pannell, Charles Mullon","doi":"10.1093/jeb/voae136","DOIUrl":"10.1093/jeb/voae136","url":null,"abstract":"Dioecious plants are frequently sexually dimorphic. Such dimorphism, which reflects responses to selection acting in opposite directions for male and female components of fitness, is commonly thought to emerge after separate sexes evolved from hermaphroditism. But associations between allocation to male and female function and traits under sexual conflict may well also develop in hermaphroditic ancestors. Here, we show that variation in sex allocation and a trait under sexual conflict inevitably generates an advantage to sexual specialization, fuelling the transition to dioecy. In the absence of constraints, this leads to the joint evolution of separate sexes and sexual dimorphism through the build-up of an association between sex allocation and the conflict trait, such that eventually the population consists of unisexuals expressing their sex-specific optima. We then investigate how such association might materialize genetically, either via recombination suppression or via sex-dependent expression, and show that the genetic architecture of sex allocation and the conflict trait readily evolves to produce the association favoured by selection. Finally and in agreement with previous theory, we demonstrate that limited dispersal and self-fertilization, which are pervasive ecological characteristics of flowering plants, can offset the advantage of sexual specialization generated by sexual conflict and thus maintain hermaphroditism. Taken together, our results indicate that advantages to sexual specialization are inevitable when there is conflict between sexual functions in hermaphrodites, but these advantages can be counterbalanced by ecological benefits of hermaphroditism.","PeriodicalId":50198,"journal":{"name":"Journal of Evolutionary Biology","volume":" ","pages":"903-919"},"PeriodicalIF":2.3,"publicationDate":"2025-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142523546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The contribution of small RNAs to the evolution of separate sexes and sex chromosomes in the plant Silene latifolia. 小rna对植物沉默叶性别分化和性染色体进化的贡献。

IF 2.3 3区生物学

Journal of Evolutionary Biology Pub Date : 2025-08-02 DOI: 10.1093/jeb/voaf051

Eddy Mendoza-Galindo, Aline Muyle

{"title":"The contribution of small RNAs to the evolution of separate sexes and sex chromosomes in the plant Silene latifolia.","authors":"Eddy Mendoza-Galindo, Aline Muyle","doi":"10.1093/jeb/voaf051","DOIUrl":"10.1093/jeb/voaf051","url":null,"abstract":"Dioecy is a breeding system with separate females and males, where sex can be determined by sex chromosomes (for instance, XY males and XX females). Dioecy is generally associated with the evolution of sexual dimorphism. In this study, we tested whether small RNAs (sRNAs) play a role in sexual dimorphism and sex chromosome evolution in Silene latifolia. We generated new data for female and male sRNAs and DNA methylation. We showed that sRNAs are most of the time female-biased in S. latifolia, suggesting that the presence of the Y chromosome globally impacts the epigenome by diluting sRNAs genome-wide in males. We found limited evidence for the regulation of sex-biased genes by sRNAs, but we nonetheless identified a male-biased transcription factor that may potentially be regulated by sex-biased RNA-directed DNA methylation. This transcription factor might contribute to male traits through the regulation of key factors in sex determination and phenotypic sexual dimorphism. Finally, we compared female and male sRNA mapping along the S. latifolia sex chromosomes. We found that X and Y genes are targeted by significantly more sRNAs in males compared to females and pseudoautosomal region genes. Our results suggest that Y genes silencing following Y degeneration leads to the formation of sRNAs that can interact with both X and Y genes in males due to X-Y sequence homology. Our work calls for future investigation of the impact of these sRNAs generated from the Y chromosome on X gene expression in males.","PeriodicalId":50198,"journal":{"name":"Journal of Evolutionary Biology","volume":" ","pages":"952-967"},"PeriodicalIF":2.3,"publicationDate":"2025-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144038633","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Tree of Sex consortium: a global initiative for studying the evolution of reproduction in eukaryotes. 性之树联盟：研究真核生物生殖进化的全球性倡议。

IF 2.3 3区生物学

Journal of Evolutionary Biology Pub Date : 2025-08-02 DOI: 10.1093/jeb/voaf053

Daniel Jeffries, Chiara Benvenuto, Astrid Böhne, Christelle Fraïsse, Sònia Garcia, Paul Jay, Lukáš Kratochvíl, Caitlin E McDonough-Goldstein, Aurora Ruiz-Herrera, Cibele G Sotero-Caio, Nicole Valenzuela, Melissa A Wilson, Kamil S Jaron

{"title":"The Tree of Sex consortium: a global initiative for studying the evolution of reproduction in eukaryotes.","authors":"Daniel Jeffries, Chiara Benvenuto, Astrid Böhne, Christelle Fraïsse, Sònia Garcia, Paul Jay, Lukáš Kratochvíl, Caitlin E McDonough-Goldstein, Aurora Ruiz-Herrera, Cibele G Sotero-Caio, Nicole Valenzuela, Melissa A Wilson, Kamil S Jaron","doi":"10.1093/jeb/voaf053","DOIUrl":"10.1093/jeb/voaf053","url":null,"abstract":"Reproduction is a fundamental aspect of life that affects all levels of biology, from genomes and development to population dynamics and diversification. The first Tree of Sex database synthesized a vast diversity of reproductive strategies and their intriguing distribution throughout eukaryotes. A decade on, we are reviving this initiative and greatly expanding its scope to provide the most comprehensive integration of knowledge on eukaryotic reproduction to date. In this perspective, we first identify important gaps in our current knowledge of reproductive strategies across eukaryotes. We then highlight a selection of questions that will benefit most from this new Tree of Sex project, including those related to the evolution of sex, modes of sex determination, sex chromosomes, and the consequences of various reproductive strategies. Finally, we outline our vision for the new Tree of Sex database and the consortium that will create it (treeofsex.org). The new database will cover all Eukaryota and include a wide selection of biological traits. It will also incorporate genomic data types that were scarce or non-existent at the time of the first Tree of Sex initiative. The new database will be publicly accessible, stable, and self-sustaining, thus greatly improving the accessibility of reproductive knowledge to researchers across disciplines for years to come. Lastly, the consortium will persist after the database is created to serve as a collaborative framework for research, prioritizing ethical standards in the collection, use, and sharing of reproductive data. The new Tree of Sex consortium is open, and we encourage all who are interested in this topic to join us.","PeriodicalId":50198,"journal":{"name":"Journal of Evolutionary Biology","volume":" ","pages":"861-886"},"PeriodicalIF":2.3,"publicationDate":"2025-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12317844/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144050798","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The evolution of sex-specific gene expression in polygenic traits. 多基因性状中性别特异性基因表达的进化。

IF 2.3 3区生物学

Journal of Evolutionary Biology Pub Date : 2025-08-02 DOI: 10.1093/jeb/voaf050

Ewan Flintham

{"title":"The evolution of sex-specific gene expression in polygenic traits.","authors":"Ewan Flintham","doi":"10.1093/jeb/voaf050","DOIUrl":"10.1093/jeb/voaf050","url":null,"abstract":"Selection often favours different phenotypes in males and females, driving the evolution of sex-specific genetic architectures that facilitate sexual dimorphism. Previous theory based on single-locus models has shown how such architecture can evolve through modifiers of gene expression and allelic dominance in males and females. Here, I consider the evolution of gene expression in polygenic traits experiencing sex-specific selection. In such traits, I find that sexual dimorphism evolves more readily through sex-specific gene amplification, whereby genes differ in their absolute expression levels between the sexes, than through the evolution of sex-specific dominance across loci, which requires strong sexual antagonism. Furthermore, I show that the type of genetic architecture that evolves through sex-specific amplification, namely the number and nature of sex-biased genes, is highly sensitive to the distance between optimal male and female trait values relative to the number of loci contributing to a trait, i.e., to the level of genetic redundancy for sexual dimorphism. Together these results indicate that genetic architectures resulting from sex-specific selection are highly dependent on the genetic basis of the trait of interest and that this creates challenges when interpreting current metrics of sexual antagonism.","PeriodicalId":50198,"journal":{"name":"Journal of Evolutionary Biology","volume":" ","pages":"939-951"},"PeriodicalIF":2.3,"publicationDate":"2025-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144175144","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Investigation of sex determination in African cichlids reveals lack of fixed sex chromosomes in wild populations. 对非洲慈鲷性别决定的研究表明，野生种群缺乏固定的性染色体。

IF 2.3 3区生物学

Journal of Evolutionary Biology Pub Date : 2025-08-02 DOI: 10.1093/jeb/voaf013

Sophie Helen Smith, Sandra Kukowka, Astrid Böhne

{"title":"Investigation of sex determination in African cichlids reveals lack of fixed sex chromosomes in wild populations.","authors":"Sophie Helen Smith, Sandra Kukowka, Astrid Böhne","doi":"10.1093/jeb/voaf013","DOIUrl":"10.1093/jeb/voaf013","url":null,"abstract":"Sex chromosomes are theorized to stop recombining and become fixed, yet many taxa show ambiguous genomic signals of sex consistent with either continuous recombination or sex chromosome turnover. Elucidating the basis of sex chromosome conservation or alternatively, turnover, requires comparative studies among natural populations with shared evolutionary histories. The African Great Lake radiations of cichlid fishes display an outstanding propensity to rapidly evolve novel sex-linked regions, yet older cichlid lineages external to these radiations seem to show conservation of a few sex chromosomes. Here, we studied sex-determining regions of species uniquely representing two older lineages within Lake Tanganyika; Oreochromis tanganicae (Oreochromini) and Tylochromis polylepis (Tylochromini). Using a combined SNP- and kmer-based approach, we confirm a ZW system on linkage group (LG) 3 in O. tanganicae, but not the previously proposed sex-determining gene. However, in T. polylepis, no clear region of sex-association could be identified, although kmer-based analyses point towards LG12 as a candidate sex chromosome. Additionally, we investigated four other species from older, non-East African radiation lineages and confirmed LG3 to be frequently associated with sex, but also found stronger signals of sex association on different chromosomes not previously discovered. Combined, these results suggest that homomorphic sex chromosomes are a feature of African cichlids at large. LG3 frequently harbours regions of sex-linkage, but is often polygenic with more strongly sex-linked regions on other chromosomes, possibly denoting its ancestral function as sex-determining across African cichlids, that leaves traces as novel sex-determining regions emerge. Our investigation captures this in a phylogenetic context, from emergence to fixation, or turnover to a new sex chromosome.","PeriodicalId":50198,"journal":{"name":"Journal of Evolutionary Biology","volume":" ","pages":"980-999"},"PeriodicalIF":2.3,"publicationDate":"2025-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143411379","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Persistence of the ecological niche in pond damselflies underlies a stable adaptive zone despite varying selection. 池塘豆娘生态位的持续存在是一个稳定的适应带的基础。

IF 2.1 3区生物学

Journal of Evolutionary Biology Pub Date : 2025-07-21 DOI: 10.1093/jeb/voaf040

Anjali Gupta, Erik I Svensson, Henrik Frietsch, Masahito Tsuboi

{"title":"Persistence of the ecological niche in pond damselflies underlies a stable adaptive zone despite varying selection.","authors":"Anjali Gupta, Erik I Svensson, Henrik Frietsch, Masahito Tsuboi","doi":"10.1093/jeb/voaf040","DOIUrl":"10.1093/jeb/voaf040","url":null,"abstract":"Following the development of regression-based methods to estimate natural and sexual selection, evolutionary biologists have quantified the strength, mode, and direction of selection in natural populations. Although this approach has been successful, its limitations include the lack of replication across species, which compromises the generality of the inferences beyond microevolutionary time scales. Here, we carried out a comparative study of selection on wing shape and body size across multiple populations of two closely related pond damselflies: Enallagma cyathigerum and Ischnura elegans (Odonata: Coenagrionidae). We found weak stabilizing selection on wing shape in both sexes and no evidence that selection on this trait differed between the species. In contrast, selection on body size was curvilinear in males and directional in females, with differences in form (males) and intensity (females) between the species. By analyzing selection in each local pond, we found that selection on male body size was shaped by various population characteristics that reflect local mating systems. Furthermore, the relationship between mating system characteristics and directional selection was remarkably consistent across these species. Finally, we present a graphical model that links contemporary selection with macroevolution. Based on this model, we conclude that the persistence of ecological modes of life in pond damselflies explains why varying selection in nature may still result in a stable adaptive zone lasting millions of years.","PeriodicalId":50198,"journal":{"name":"Journal of Evolutionary Biology","volume":" ","pages":"728-743"},"PeriodicalIF":2.1,"publicationDate":"2025-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143812809","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Why zoologists should not treat the automatic transmission advantage as an afterthought: a commentary on Clo et al. (2025). 为什么动物学家不应该把自动变速器的优势视为事后的想法：对Clo等人（2025）的评论。

IF 2.1 3区生物学

Journal of Evolutionary Biology Pub Date : 2025-07-21 DOI: 10.1093/jeb/voaf059

Thomas A Keaney, Hanna Kokko

引用次数: 0

Like mother, like daughter? Phenotypic plasticity, and heritability of size in a parthenogenetic wasp. 有其母必有其女？孤雌生殖黄蜂体型的表型可塑性、环境共变和遗传力。

IF 2.1 3区生物学

Journal of Evolutionary Biology Pub Date : 2025-07-21 DOI: 10.1093/jeb/voaf027

Alicia Tovar, Scott Monahan, Trevor Mugoya, Adrian Kristan, Walker Welch, Ryan Dettmers, Camila Arce, Theresa Buck, Michele Ruben, Alexander Rothenberg, Roxane Saisho, Ryan Cartmill, Timothy Skaggs, Robert Reyes, Marianne J Lee, John Obrycki, William Kristan, Arun Sethuraman

{"title":"Like mother, like daughter? Phenotypic plasticity, and heritability of size in a parthenogenetic wasp.","authors":"Alicia Tovar, Scott Monahan, Trevor Mugoya, Adrian Kristan, Walker Welch, Ryan Dettmers, Camila Arce, Theresa Buck, Michele Ruben, Alexander Rothenberg, Roxane Saisho, Ryan Cartmill, Timothy Skaggs, Robert Reyes, Marianne J Lee, John Obrycki, William Kristan, Arun Sethuraman","doi":"10.1093/jeb/voaf027","DOIUrl":"10.1093/jeb/voaf027","url":null,"abstract":"Parthenogenetic wasps provide an ideal natural experiment to study the heritability, plasticity, and microevolutionary dynamics of body size. Dinocampus coccinellae (Hymenoptera: Braconidae, Euphorinae) is a solitary, generalist braconid parasitoid wasp that reproduces through thelytokous parthenogenesis and parasitizes over 50 diverse species of coccinellid ladybeetles worldwide as hosts. Here, we designed an experiment with parthenogenetic lines of D. coccinellae presented with three different host ladybeetle species of varying sizes, across multiple generations to investigate heritability and plasticity of body size measured via a combination of morphometric variables such as thorax width, abdominal width, and wing length in D. coccinellae. We expected positively correlated parent-offspring parasitoid regressions, indicative of heritable size variation, from unilineal (parent and offspring reared on same host species) lines, since these restrict environmental variation in phenotypes. In contrast, because multilineal (parent and offspring reared on different host species) lines would induce phenotypic plasticity of clones reared in varying environments, we expected negatively correlated parent-offspring parasitoid regressions. Our results indicate (1) little heritable variation in body size, (2) strong independence of offspring size on the host environment, and (3) small mothers produce larger offspring, and vice versa, independent of host. We then model the evolution of size and host-shifting under a constrained fecundity advantage model of Cope's Law using a Hidden Markov Model, showing that D. coccinellae likely has fitness advantages to maintain plasticity in body size despite parthenogenetic reproduction.","PeriodicalId":50198,"journal":{"name":"Journal of Evolutionary Biology","volume":" ","pages":"744-757"},"PeriodicalIF":2.1,"publicationDate":"2025-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143659243","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Variation in prey availability over time shaped the extinction dynamics of sabre-toothed cats. 随着时间的推移，猎物数量的变化决定了剑齿虎的灭绝动态。

IF 2.1 3区生物学

Journal of Evolutionary Biology Pub Date : 2025-07-21 DOI: 10.1093/jeb/voaf043

João C S Nascimento, Mathias M Pires

{"title":"Variation in prey availability over time shaped the extinction dynamics of sabre-toothed cats.","authors":"João C S Nascimento, Mathias M Pires","doi":"10.1093/jeb/voaf043","DOIUrl":"10.1093/jeb/voaf043","url":null,"abstract":"The role of ecological interactions and abiotic factors in shaping macroevolutionary patterns has been extensively debated. Yet, the effect of predator-prey interactions on diversification dynamics is unclear. Here, we test the influence of predator-prey interactions in the diversification of sabre-toothed cats, a subfamily of felids (Felidae: Machairodontinae) that developed a highly specialized morphology, the notoriously long upper canines. This morphology has been associated with a high degree of trophic dependence on large prey, which is assumed as one of the main reasons for the group's demise. To test the hypothesis that prey availability affected the diversification of sabretooths we examined whether shifts in speciation and extinction rates were linked with changes in the species richness of their potential prey clades. The only association we detected was between the increase in extinction rates of North American sabretooths and the decline in Equidae richness. However, when accounting for the prey richness per species, regardless of taxonomic affiliation of the prey, we found that the endpoint of most sabretooth taxa occurred when prey richness for that taxon was at its lowest. Our analyses then suggested that reduced prey richness was associated with increased extinction risk. These results support the hypothesis that the extinction of sabretooths was associated with the decline in megafauna, but extend it to more remote times, millions of years before their final demise, suggesting that prey availability contributed to drive the diversification dynamics of the group. More broadly, our findings highlight the importance of ecological interactions in shaping macroevolutionary patterns.","PeriodicalId":50198,"journal":{"name":"Journal of Evolutionary Biology","volume":" ","pages":"758-768"},"PeriodicalIF":2.1,"publicationDate":"2025-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144054578","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0