多基因性状中性别特异性基因表达的进化。

IF 2.3 3区 生物学 Q3 ECOLOGY
Ewan Flintham
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引用次数: 0

摘要

选择往往倾向于雄性和雌性的不同表型,从而推动性别特异性遗传结构的进化,从而促进两性二态性。先前基于单位点模型的理论表明,这种结构是如何通过基因表达和等位基因优势的修饰因子在雄性和雌性中进化的。在这里,我考虑基因表达的进化在多基因性状经历性别特异性选择。在这些性状中,我发现两性二态性更容易通过性别特异性基因扩增而进化,即基因在两性之间的绝对表达水平不同,而不是通过基因座间性别特异性优势的进化,这需要强烈的性别对抗。此外,我还表明,通过性别特异性扩增进化而来的遗传结构类型,即性别偏倚基因的数量和性质,对最佳雄性和雌性性状值之间的距离(相对于对性状有贡献的位点数量)高度敏感,也就是说,对性弱视的遗传冗余水平高度敏感。总之,这些结果表明,由性别特异性选择产生的遗传结构高度依赖于感兴趣性状的遗传基础,这在解释当前的性别对抗指标时带来了挑战。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The evolution of sex-specific gene expression in polygenic traits.

Selection often favours different phenotypes in males and females, driving the evolution of sex-specific genetic architectures that facilitate sexual dimorphism. Previous theory based on single-locus models has shown how such architecture can evolve through modifiers of gene expression and allelic dominance in males and females. Here, I consider the evolution of gene expression in polygenic traits experiencing sex-specific selection. In such traits, I find that sexual dimorphism evolves more readily through sex-specific gene amplification, whereby genes differ in their absolute expression levels between the sexes, than through the evolution of sex-specific dominance across loci, which requires strong sexual antagonism. Furthermore, I show that the type of genetic architecture that evolves through sex-specific amplification, namely the number and nature of sex-biased genes, is highly sensitive to the distance between optimal male and female trait values relative to the number of loci contributing to a trait, i.e., to the level of genetic redundancy for sexual dimorphism. Together these results indicate that genetic architectures resulting from sex-specific selection are highly dependent on the genetic basis of the trait of interest and that this creates challenges when interpreting current metrics of sexual antagonism.

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来源期刊
Journal of Evolutionary Biology
Journal of Evolutionary Biology 生物-进化生物学
CiteScore
4.20
自引率
4.80%
发文量
152
审稿时长
3-6 weeks
期刊介绍: It covers both micro- and macro-evolution of all types of organisms. The aim of the Journal is to integrate perspectives across molecular and microbial evolution, behaviour, genetics, ecology, life histories, development, palaeontology, systematics and morphology.
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