V Paradis, A Des Roches, C Elbany, C Braun, F J Graham, K Samaan, R Labrosse, L Paradis, P Bégin
{"title":"Use of a 24-Hour Hotline vs Voicemail for Off-Hour Support During Oral Immunotherapy for Food Allergy.","authors":"V Paradis, A Des Roches, C Elbany, C Braun, F J Graham, K Samaan, R Labrosse, L Paradis, P Bégin","doi":"10.18176/jiaci.1063","DOIUrl":"10.18176/jiaci.1063","url":null,"abstract":"","PeriodicalId":50173,"journal":{"name":"Journal of Investigational Allergology and Clinical Immunology","volume":" ","pages":"0"},"PeriodicalIF":6.1,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143544084","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
O Neth, L Alsina, J G Rivière, E López-Granados, M E Seoane-Reula, L I González Granado, S Sánchez-Ramón, C Rodríguez-Gallego
{"title":"Spanish Consensus on the Diagnosis and Management of Patients With Activated PI3K Delta Syndrome (APDS).","authors":"O Neth, L Alsina, J G Rivière, E López-Granados, M E Seoane-Reula, L I González Granado, S Sánchez-Ramón, C Rodríguez-Gallego","doi":"10.18176/jiaci.1059","DOIUrl":"https://doi.org/10.18176/jiaci.1059","url":null,"abstract":"<p><p>Activated phosphoinositide 3-kinase (PI3K) delta syndrome (APDS) is an ultrarare genetic disorder characterized by overlapping immunodeficiency and immune dysregulation. Its diagnosis poses challenges owing to its clinical similarities with other inborn errors of immunity (IEIs), compounded by the absence of targeted treatments in today's medical landscape. The standard approach involves symptom management, reducing infection through immunoglobulin replacement therapy and prophylactic antimicrobials, and treating immune dysregulation with immunomodulators. This approach considerably hampers effective management of APDS, as the diverse nature of the disease necessitates a personalized strategy, in which the advantages and risks of immunosuppression are weighed against the potential for recurrent infections and lymphoproliferative complications. To address these challenges, a group of Spanish experts in the management of IEIs, including APDS, collaborated to develop Delphi-based consensus recommendations. The primary goal of the initiative was to offer guidance on various aspects of this complex disease, marking a pioneering effort in Europe. The consensus aims to facilitate early diagnosis and provide clues for individual patient-based decisions that could favor balanced risk-benefit estimations for treatment.</p>","PeriodicalId":50173,"journal":{"name":"Journal of Investigational Allergology and Clinical Immunology","volume":" ","pages":"0"},"PeriodicalIF":6.1,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143543915","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
V Pardo-Manrique, V Amat-Samaranch, M Pascal, D Loli-Ausejo, M C Sánchez-Fernández, M Ruano-Zaragoza
{"title":"Hidden Dangers of Oral Contrast Media: Delayed Hypersensitivity to Sodium Amidotrizoate and Meglumine Amidotrizoate (Gastrografin).","authors":"V Pardo-Manrique, V Amat-Samaranch, M Pascal, D Loli-Ausejo, M C Sánchez-Fernández, M Ruano-Zaragoza","doi":"10.18176/jiaci.1055","DOIUrl":"https://doi.org/10.18176/jiaci.1055","url":null,"abstract":"","PeriodicalId":50173,"journal":{"name":"Journal of Investigational Allergology and Clinical Immunology","volume":" ","pages":"0"},"PeriodicalIF":6.1,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143494355","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A Morales-Hidalgo, M Pérez-Montoya, J A Cañas, M Valverde-Monge, J M Rodrigo-Muñoz, M Gil-Martínez, A Gómez-López, M Otal-Buesa, V Del Pozo Abejón, M Fernández-Nieto
{"title":"Basophil Activation Test: An Additional Diagnostic Tool in Vitamin B12 Allergy.","authors":"A Morales-Hidalgo, M Pérez-Montoya, J A Cañas, M Valverde-Monge, J M Rodrigo-Muñoz, M Gil-Martínez, A Gómez-López, M Otal-Buesa, V Del Pozo Abejón, M Fernández-Nieto","doi":"10.18176/jiaci.1048","DOIUrl":"https://doi.org/10.18176/jiaci.1048","url":null,"abstract":"","PeriodicalId":50173,"journal":{"name":"Journal of Investigational Allergology and Clinical Immunology","volume":" ","pages":"0"},"PeriodicalIF":6.1,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143494354","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
D Betancor, M Valverde-Monge, J L Díaz-Recuero, M E Jo-Velasco, V Del Pozo, J Sastre
{"title":"Generalized Eczema as a Transient Paradoxical Adverse Effect of Dupilumab.","authors":"D Betancor, M Valverde-Monge, J L Díaz-Recuero, M E Jo-Velasco, V Del Pozo, J Sastre","doi":"10.18176/jiaci.1051","DOIUrl":"https://doi.org/10.18176/jiaci.1051","url":null,"abstract":"","PeriodicalId":50173,"journal":{"name":"Journal of Investigational Allergology and Clinical Immunology","volume":" ","pages":"0"},"PeriodicalIF":6.1,"publicationDate":"2025-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143460458","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A Lund, B Dorn, T Jakob, L H Christensen, F Jabs, E Spillner
{"title":"A Fully Human Monoclonal Antibody Isolated From a Beekeeper Targets the Immunodominant IgE Epitope of Api m 10.","authors":"A Lund, B Dorn, T Jakob, L H Christensen, F Jabs, E Spillner","doi":"10.18176/jiaci.1029","DOIUrl":"10.18176/jiaci.1029","url":null,"abstract":"","PeriodicalId":50173,"journal":{"name":"Journal of Investigational Allergology and Clinical Immunology","volume":" ","pages":"55-57"},"PeriodicalIF":6.1,"publicationDate":"2025-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142631557","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
R N Vera-Berrios, L Uriarte Vega, G Marco-Martín, M Fernández-Rivas
{"title":"Nonmandatory Labeled Legumes Are an Emergent Safety Concern: An Illustrative Case Report.","authors":"R N Vera-Berrios, L Uriarte Vega, G Marco-Martín, M Fernández-Rivas","doi":"10.18176/jiaci.1020","DOIUrl":"10.18176/jiaci.1020","url":null,"abstract":"","PeriodicalId":50173,"journal":{"name":"Journal of Investigational Allergology and Clinical Immunology","volume":" ","pages":"58-60"},"PeriodicalIF":6.1,"publicationDate":"2025-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142331424","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
P Gutiérrez-Canales, C Fernández-Lozano, V Alba-Pérez, A Ruiz-Granados, L Díaz-Montalvo, J Martínez-Botas, E Solano-Solares
{"title":"Unveiling the Immunological Mechanism Underlying a Cutaneous Adverse Reaction to Enfortumab Vedotin: A Case Report Based on the Lymphocyte Transformation Test.","authors":"P Gutiérrez-Canales, C Fernández-Lozano, V Alba-Pérez, A Ruiz-Granados, L Díaz-Montalvo, J Martínez-Botas, E Solano-Solares","doi":"10.18176/jiaci.1023","DOIUrl":"10.18176/jiaci.1023","url":null,"abstract":"","PeriodicalId":50173,"journal":{"name":"Journal of Investigational Allergology and Clinical Immunology","volume":" ","pages":"63-65"},"PeriodicalIF":6.1,"publicationDate":"2025-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142773951","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
D Betancor, A Gómez-López, B Barroso, M Valverde-Monge, J A Cañas, J M Rodrigo-Muñoz, V Del Pozo, J Sastre
{"title":"Are Biosimilars of Biologics the Same as the Reference Drug in Terms of Allergy? Selective Allergy to Tocilizumab Biosimilar.","authors":"D Betancor, A Gómez-López, B Barroso, M Valverde-Monge, J A Cañas, J M Rodrigo-Muñoz, V Del Pozo, J Sastre","doi":"10.18176/jiaci.1025","DOIUrl":"10.18176/jiaci.1025","url":null,"abstract":"","PeriodicalId":50173,"journal":{"name":"Journal of Investigational Allergology and Clinical Immunology","volume":" ","pages":"68-69"},"PeriodicalIF":6.1,"publicationDate":"2025-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142631600","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M Lozano-Espinosa, N Rodríguez-Otero, D Antolín-Amérigo, F Gordo Vidal, A Muriel, R de Pablo, S Quirce
{"title":"Characteristics of Asthma Patients Admitted to the Intensive Care Unit of a Tertiary University Hospital in Madrid, Spain: A 5-Year Experience.","authors":"M Lozano-Espinosa, N Rodríguez-Otero, D Antolín-Amérigo, F Gordo Vidal, A Muriel, R de Pablo, S Quirce","doi":"10.18176/jiaci.1021","DOIUrl":"10.18176/jiaci.1021","url":null,"abstract":"","PeriodicalId":50173,"journal":{"name":"Journal of Investigational Allergology and Clinical Immunology","volume":" ","pages":"50-52"},"PeriodicalIF":6.1,"publicationDate":"2025-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142631605","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}