Chen Chen, Qi Liu, Yao Li, Jing-Wen Yu, Shu-Di Wang, Jia-Li Xu, Li Liu
{"title":"Circulating microRNA-33b levels are associated with the presence and severity of coronary heart disease","authors":"Chen Chen, Qi Liu, Yao Li, Jing-Wen Yu, Shu-Di Wang, Jia-Li Xu, Li Liu","doi":"10.1080/00365513.2024.2340751","DOIUrl":"https://doi.org/10.1080/00365513.2024.2340751","url":null,"abstract":"MicroRNA-33b (miR-33b) affected various biological pathways in regulating cholesterol homeostasis which may link to the pathogenesis of atherosclerotic lesions. However, whether this marker is asso...","PeriodicalId":501634,"journal":{"name":"Scandinavian Journal of Clinical and Laboratory Investigation","volume":"6 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140594389","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Johann Sigurjonsson, David Grubb, Anders Grubb, Anders Christensson, Carl M. Öberg, Per Ederoth, Sasha Koul, Matthias Götberg, Troels Yndigegn, Tim Tödt, Benedicte Viterius, Henrik Bjursten
{"title":"A study of size-selective renal elimination using a novel human model","authors":"Johann Sigurjonsson, David Grubb, Anders Grubb, Anders Christensson, Carl M. Öberg, Per Ederoth, Sasha Koul, Matthias Götberg, Troels Yndigegn, Tim Tödt, Benedicte Viterius, Henrik Bjursten","doi":"10.1080/00365513.2024.2338742","DOIUrl":"https://doi.org/10.1080/00365513.2024.2338742","url":null,"abstract":"The recently discovered selective glomerular hypofiltration syndromes have increased interest in the actual elimination of molecules in the human kidney. In the present study, a novel human model w...","PeriodicalId":501634,"journal":{"name":"Scandinavian Journal of Clinical and Laboratory Investigation","volume":"2019 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140594752","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Plasma metabolomics for diagnostic biomarkers on ectopic pregnancy","authors":"Ozan Kaplan, Sezin Ertürk Aksakal, Bilge Başak Fidan, Yaprak Engin-Üstün, Mustafa Çelebier","doi":"10.1080/00365513.2024.2317763","DOIUrl":"https://doi.org/10.1080/00365513.2024.2317763","url":null,"abstract":"Metabolomics is a relatively novel omics tool to provide potential biomarkers for early diagnosis of the diseases and to insight the pathophysiology not having discussed ever before. In the present...","PeriodicalId":501634,"journal":{"name":"Scandinavian Journal of Clinical and Laboratory Investigation","volume":"175 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139969463","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Reference standard analysis of multiple new and old plasma clearance models and renal clearance with special attention to measurement of reduced glomerular filtration rate","authors":"Carl A. Wesolowski","doi":"10.1080/00365513.2023.2275278","DOIUrl":"https://doi.org/10.1080/00365513.2023.2275278","url":null,"abstract":"Nine models were evaluated as candidate glomerular filtration rate (GFR) reference standards in three datasets using [51Cr(EDTA)]– or [169Yb(DTPA)]2− anions in 98 studies. Noncompartmental methods ...","PeriodicalId":501634,"journal":{"name":"Scandinavian Journal of Clinical and Laboratory Investigation","volume":"122 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139459278","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Zhumin Sun, Yang Zhang, Haiyan Zhou, Jingyun Li, Yue Zhou, Liyun Wang
{"title":"Serum interα-trypsin inhibitor heavy chain H4 may be an anti-inflammatory marker reflecting disease risk, activity and treatment outcome of ankylosing spondylitis","authors":"Zhumin Sun, Yang Zhang, Haiyan Zhou, Jingyun Li, Yue Zhou, Liyun Wang","doi":"10.1080/00365513.2023.2250986","DOIUrl":"https://doi.org/10.1080/00365513.2023.2250986","url":null,"abstract":"Interα-trypsin inhibitor heavy chain H4 (ITIH4) modulates inflammation and immunity, which take part in the pathogenesis of ankylosing spondylitis (AS). The current research intended to discover th...","PeriodicalId":501634,"journal":{"name":"Scandinavian Journal of Clinical and Laboratory Investigation","volume":"16 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139065629","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Plasma or serum 5-hydroxyindoleacetic acid can be used interchangeably in patients with neuroendocrine tumours","authors":"Mfon Ewang-Emukowhate, Krithika Subramaniam, Francis Lam, Aimee Hayes, Dalvinder Mandair, Christos Toumpanakis, Ashley Grossman, Devaki Nair, Martyn Caplin","doi":"10.1080/00365513.2023.2286645","DOIUrl":"https://doi.org/10.1080/00365513.2023.2286645","url":null,"abstract":"5-hydroxyindole acetic acid, a metabolite of serotonin, is used in the diagnosis and monitoring of patients with neuroendocrine tumours, in particular patients with small intestinal neuroendocrine ...","PeriodicalId":501634,"journal":{"name":"Scandinavian Journal of Clinical and Laboratory Investigation","volume":"198 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138743158","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Marco Rosetti, Melania Olivieri, Valentina Polli, Evita Massari, Marta Monti, Alice Clementoni, Virginia Libri, Giovanni Poletti, Tommaso Fasano
{"title":"Effects of the presence of fibrin strands on complete blood count parameters","authors":"Marco Rosetti, Melania Olivieri, Valentina Polli, Evita Massari, Marta Monti, Alice Clementoni, Virginia Libri, Giovanni Poletti, Tommaso Fasano","doi":"10.1080/00365513.2023.2292601","DOIUrl":"https://doi.org/10.1080/00365513.2023.2292601","url":null,"abstract":"Published in Scandinavian Journal of Clinical and Laboratory Investigation (Ahead of Print, 2023)","PeriodicalId":501634,"journal":{"name":"Scandinavian Journal of Clinical and Laboratory Investigation","volume":"197 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138688151","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Stability of potassium, calcium and phosphorus electrolytes in three different tubes in patients with essential thrombocytosis","authors":"Murat Aksit, Merve Zeytinli Aksit, Ayfer Colak, Banu Isbilen Basok, Cengiz Ceylan","doi":"10.1080/00365513.2023.2289162","DOIUrl":"https://doi.org/10.1080/00365513.2023.2289162","url":null,"abstract":"Proper blood collection and timely analysis are vital steps for reliable results. This study aims to compare potassium(K), calcium(Ca), and phosphorus(P) concentrations in serum separator tube (SST...","PeriodicalId":501634,"journal":{"name":"Scandinavian Journal of Clinical and Laboratory Investigation","volume":"585 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138558473","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Luis García de Guadiana-Romualdo, María Isabel Díaz López, Elena Crespo Álvarez, Álvaro Martínez Manzano, Eloísa Urrechaga, Manuel Tomás Orgaz Morales
{"title":"Usefulness of the extended inflammatory parameters related to neutrophil activation reported on Sysmex XN-1000 haematology analyser as indicators of acute appendicitis: comparison with canonical inflammatory laboratory tests.","authors":"Luis García de Guadiana-Romualdo, María Isabel Díaz López, Elena Crespo Álvarez, Álvaro Martínez Manzano, Eloísa Urrechaga, Manuel Tomás Orgaz Morales","doi":"10.1080/00365513.2022.2116726","DOIUrl":"https://doi.org/10.1080/00365513.2022.2116726","url":null,"abstract":"","PeriodicalId":501634,"journal":{"name":"Scandinavian Journal of Clinical and Laboratory Investigation","volume":" ","pages":"492-494"},"PeriodicalIF":2.1,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40337397","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Maria Kløjgaard Skytthe, Anna Lahn Sørensen, Dorle Hennig, Maria Boysen Sandberg, Lars Melholt Rasmussen, Holger J Møller, Karsten Skjødt, Jonas Heilskov Graversen, Søren Kragh Moestrup
{"title":"Re-evalution of the measurement of haptoglobin in human plasma samples.","authors":"Maria Kløjgaard Skytthe, Anna Lahn Sørensen, Dorle Hennig, Maria Boysen Sandberg, Lars Melholt Rasmussen, Holger J Møller, Karsten Skjødt, Jonas Heilskov Graversen, Søren Kragh Moestrup","doi":"10.1080/00365513.2022.2122077","DOIUrl":"https://doi.org/10.1080/00365513.2022.2122077","url":null,"abstract":"<p><p>Haptoglobin (Hp) is an abundant plasma protein scavenging hemoglobin (Hb) <i>via</i> CD163 on macrophages. This process consumes Hp, which therefore negatively correlates to hemolysis. However, exact measurements of Hp plasma levels are complicated by different phenotypes (Hp1-1, Hp2-1, and Hp2-2) forming different oligomeric states with differences in immunoreactivity. In addition, humans have an immune-cross-reactive Hp-related protein. In the present study, we developed Hp-specific monoclonal antibodies for an accurate Hp analysis of the different Hp phenotypes in a panel of 112 anonymous samples from hospitalized individuals subjected to routine Hp immunoturbidimetric measurements. The data revealed immunoturbidimetry as a reliable method in most cases but also that the use of non-phenotype-specific calibrators leads to substantial bias in the measurement of the Hp-concentration, non at least in Hp1-1 individuals. Furthermore, analysis of the Hb-dependence of the CD163 interaction with Hp1-1 and Hp2-2 showed that a higher 'cost-effectiveness' in the consumption of dimeric Hp1-1 versus multimeric Hp phenotypes is a likely contribution to the observed differences in the plasma levels of the Hp phenotypes. In conclusion, the determination of Hp phenotype and the use of phenotype-specific calibrators are essential to obtain a precise estimate of the Hp level in healthy and diseased individuals.</p>","PeriodicalId":501634,"journal":{"name":"Scandinavian Journal of Clinical and Laboratory Investigation","volume":" ","pages":"467-473"},"PeriodicalIF":2.1,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40374868","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}