Smart Molecules最新文献_第3页

Deprotonated of layered double hydroxides during electrocatalytic water oxidation for multi-cations intercalation 多阳离子插层电催化水氧化过程中层状双氢氧化物的去质子化

Smart Molecules Pub Date : 2024-04-10 DOI: 10.1002/smo.20230026

Bowen Jin, Jianxiong Gao, Yunqi Zhang, Mingfei Shao

引用次数: 0

Smart emulsion system driven by light-triggered ionic liquid molecules and its application in eco-friendly water-saving dyeing 光触发离子液体分子驱动的智能乳液系统及其在环保节水染色中的应用

Smart Molecules Pub Date : 2024-03-19 DOI: 10.1002/smo.20230030

Aiqin Gao, Jiahui Liang, Mingxiao Jing, Xiyu Song, Aiqin Hou, Kongliang Xie

{"title":"Smart emulsion system driven by light-triggered ionic liquid molecules and its application in eco-friendly water-saving dyeing","authors":"Aiqin Gao, Jiahui Liang, Mingxiao Jing, Xiyu Song, Aiqin Hou, Kongliang Xie","doi":"10.1002/smo.20230030","DOIUrl":"https://doi.org/10.1002/smo.20230030","url":null,"abstract":"The smart emulsification and demulsification system with the light response is a useful tool in various industries, including green chemistry, catalytic reaction, pharmaceuticals, and environmental remediation. Herein, an ionic liquid crystal compound with a light triggered switch based on the azobenzene group [(4-{3-methyl-1-[3-(8-octyloxyoctyl)oxy-4-oxobutanoyl]imidazo-lium-1-yl}octyl)oxy] -N-(4-methylphenyl)benzene-1,2-diazene bromide (MOIAzo), was designed and synthesized, which could cause reversible transition between emulsification and demulsification through the light trigger. The ionic liquid has an efficient photoinduced liquefaction process, which dramatically lowers the melting point of ionic liquids from 79 to 9.2 oC. This significantly broadens the liquid state temperature of the ionic liquid crystal. The ionic liquid crystal MOIAzo exhibits both photoinduced and thermally induced nematic liquid crystal properties. The smart emulsion system was effectively employed in an eco-friendly water-saving dyeing process of cationic dyes for cationic dyeable polyester (CDP) fabrics, which used only half the amount of water compared with the conventional water bath dyeing method. After dyeing, the oil and water phases can be efficiently separated through the light irradiation, and the oil phase can be reused for the subsequent dyeing process. This novel smart emulsion dyeing method greatly reduces the water consumption and wastewater discharge. MOIAzo as a light-triggered ionic liquid molecule opens up new dimensions in green chemistry.","PeriodicalId":501601,"journal":{"name":"Smart Molecules","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140166791","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Smart molecules in ophthalmology: Hydrogels as responsive systems for ophthalmic applications 眼科中的智能分子：作为眼科应用响应系统的水凝胶

Smart Molecules Pub Date : 2024-03-15 DOI: 10.1002/smo.20230021

Merve Kulbay, Kevin Yang Wu, Doanh Truong, Simon D. Tran

引用次数: 0

Precise construction of DNA origami-based materials for functional regulation on biological interface 精确构建基于 DNA 折纸的材料，实现生物界面的功能调控

Smart Molecules Pub Date : 2024-03-04 DOI: 10.1002/smo.20230032

Yushuai Wu, Xiaohui Wu, Run Tian, Yiming Wang, Baoquan Ding, Qiao Jiang

引用次数: 0

Smart chiral liquid crystal elastomers: Design, properties and application 智能手性液晶弹性体：设计、特性和应用

Smart Molecules Pub Date : 2024-02-29 DOI: 10.1002/smo.20230025

Yuan Liu, Jiazhe Ma, Yanzhao Yang, Cristian Valenzuela, Xuan Zhang, Ling Wang, Wei Feng

{"title":"Smart chiral liquid crystal elastomers: Design, properties and application","authors":"Yuan Liu, Jiazhe Ma, Yanzhao Yang, Cristian Valenzuela, Xuan Zhang, Ling Wang, Wei Feng","doi":"10.1002/smo.20230025","DOIUrl":"https://doi.org/10.1002/smo.20230025","url":null,"abstract":"Smart chiral liquid crystal elastomers are a class of soft photonic crystals with periodic nanostructures. There are two kinds of chiral liquid crystal elastomers with structural colors: cholesteric liquid crystal elastomers with a one-dimensional helical nanostructure and blue-phase liquid crystal elastomers with a three-dimensional photonic crystal nanostructure. The self-assembled nanostructure of chiral liquid crystal elastomers can be dynamically controlled under external stimulation, and the reflected color can be adjusted throughout the visible light range. Along with the development of innovative material systems and cutting-edge manufacturing technologies, researchers have proposed diverse strategies to design and synthesize chiral liquid crystal elastomers and have thoroughly investigated their properties and potential applications. Here, we provide a systematic review of the progress in the design and fabrication of smart chiral liquid crystal elastomers, focusing on the cholesteric liquid crystal elastomers via surface-enforced alignment, bar coating, 3D printing, anisotropic deswelling methods as well as the three-dimensional self-assembly of blue-phase liquid crystal elastomers without additional alignment. Smart chiral liquid crystal elastomers are able to respond quickly to external stimuli and have a wide range of applications in areas such as adaptive optics, color-changing camouflage, soft robotics, and information encryption. This review concludes with a perspective on the opportunities and challenges for the future development of smart chiral liquid crystal elastomers.","PeriodicalId":501601,"journal":{"name":"Smart Molecules","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-02-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140003015","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Activatable theranostic prodrug scaffold with tunable drug release rate for sequential photodynamic and chemotherapy 具有可调药物释放率的可激活治疗原药支架，用于光动力和化疗的连续治疗

Smart Molecules Pub Date : 2024-02-20 DOI: 10.1002/smo.20230024

Si-Yu Wang, Ying-Hao Pan, Yu-Chen Qu, Xiao-Xiao Chen, Na Shao, Li-Ya Niu, Qing-Zheng Yang

{"title":"Activatable theranostic prodrug scaffold with tunable drug release rate for sequential photodynamic and chemotherapy","authors":"Si-Yu Wang, Ying-Hao Pan, Yu-Chen Qu, Xiao-Xiao Chen, Na Shao, Li-Ya Niu, Qing-Zheng Yang","doi":"10.1002/smo.20230024","DOIUrl":"https://doi.org/10.1002/smo.20230024","url":null,"abstract":"Glutathione (GSH)-activated prodrugs are promising for overcoming the limitations of conventional anti-tumor drugs. However, current GSH-responsive disulfide groups exhibit unregulated reactivity, making it impossible to precisely control the drug release rate. We herein report a series of GSH-responsive prodrugs with a “three-in-one” molecular design by integrating a fluorescence report unit, stimuli-responsive unit and chemodrug into one scaffold with tunable aromatic nucleophilic substitution (SNAr) reactivity. The drug release rate of these prodrugs is tailored by modification of substituent groups with different electron-withdrawing or -donating abilities on the BODIPY core. Furthermore, the prodrugs self-assemble in water to form nanoparticles that serve as photosensitizers to produce reactive oxygen species upon irradiation for photodynamic therapy (PDT). The PDT process also increases the concentration of GSH in cells, further promoting the release of drugs for chemotherapy. This strategy provides a powerful platform for sequential photodynamic and chemotherapy with tunable drug release rates and synergistic therapeutic effects.","PeriodicalId":501601,"journal":{"name":"Smart Molecules","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139918132","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Smart molecular crystal switches 智能分子晶体开关

Smart Molecules Pub Date : 2024-02-16 DOI: 10.1002/smo.20230031

Ian Cheng-Yi Hou, Liang Li, Hongyu Zhang, Panče Naumov

引用次数: 0

Electron-withdrawing inductive effects enhanced strategy for protein thiol sensing and blocking agent design 电子牵引感应效应增强了蛋白质硫醇传感和阻断剂的设计策略

Smart Molecules Pub Date : 2024-02-14 DOI: 10.1002/smo.20230022

Liangwei Zhang, Shudi Liu, Xia Zhang, Jinyu Sun, Lingxin Chen

{"title":"Electron-withdrawing inductive effects enhanced strategy for protein thiol sensing and blocking agent design","authors":"Liangwei Zhang, Shudi Liu, Xia Zhang, Jinyu Sun, Lingxin Chen","doi":"10.1002/smo.20230022","DOIUrl":"https://doi.org/10.1002/smo.20230022","url":null,"abstract":"It is a great challenge to discover novel chemical reactions suitable for biological analysis in a living system. The development of novel protein thiol blocking agents is a crucial need for exploring protein thiol functions in protein refolding, signal transduction, and redox regulation. We are always keen on seeking novel chemical reactions applied to endogenous biological macromolecules or protein thiol sensing, blocking, and labeling. In the present work, we have successfully developed a novel agent to block protein thiol by enhanced electron-withdrawing inductive effects. This sensing and blocking process was detailedly monitored by UV-vis, fluorescent spectra, and SDS-Page gel separation. The spectral studies demonstrated that the agent could react ultrafastly with thiol within seconds at μM level. Furthermore, fluorescent imaging in cells and in vivo was further used for the validation of its ability to sensing and blocking thiol, providing evidence of downregulated protein thiols in Parkinson's disease. The enhanced electron-withdrawing inductive effect strategy in this work may provide a general guideline for designing protein thiol agent.","PeriodicalId":501601,"journal":{"name":"Smart Molecules","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139758438","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Recent progress in stimuli-responsive DNA-based logic gates: Design, working principles and biological applications 基于刺激响应 DNA 的逻辑门的最新进展：设计、工作原理和生物应用

Smart Molecules Pub Date : 2024-02-14 DOI: 10.1002/smo.20230023

Ling Sum Liu, Hoi Man Leung, Yuzhen Cai, Pik Kwan Lo

引用次数: 0

Benzothiazole-endoperoxide conjugates protect PC12 cells against β-amyloid-induced cell death via singlet oxygen mediated oxidative detoxification of fibrils 苯并噻唑-内过氧化物共轭物通过单线态氧介导的纤维氧化解毒作用保护 PC12 细胞免受 β 淀粉样蛋白诱导的细胞死亡影响

Smart Molecules Pub Date : 2024-01-04 DOI: 10.1002/smo.20230019

Hao Wu, Lei Wang, Xiao Qian, Wanwan Wang, Yu Si, Rensong Sun, Engin U. Akkaya

引用次数: 0