Journal of Membrane Biology最新文献_第8页

Membrane Proteins in Plant Salinity Stress Perception, Sensing, and Response. 植物盐胁迫感知、感知和响应中的膜蛋白。

IF 2.4 4区生物学

Journal of Membrane Biology Pub Date : 2023-04-01 DOI: 10.1007/s00232-023-00279-9

Sanhita Banik, Debajyoti Dutta

{"title":"Membrane Proteins in Plant Salinity Stress Perception, Sensing, and Response.","authors":"Sanhita Banik, Debajyoti Dutta","doi":"10.1007/s00232-023-00279-9","DOIUrl":"https://doi.org/10.1007/s00232-023-00279-9","url":null,"abstract":"Plants have several mechanisms to endure salinity stress. The degree of salt tolerance varies significantly among different terrestrial crops. Proteins at the plant's cell wall and membrane mediate different physiological roles owing to their critical positioning between two distinct environments. A specific membrane protein is responsible for a single type of activity, such as a specific group of ion transport or a similar group of small molecule binding to exert multiple cellular effects. During salinity stress in plants, membrane protein functions: ion homeostasis, signal transduction, redox homeostasis, and solute transport are essential for stress perception, signaling, and recovery. Therefore, comprehensive knowledge about plant membrane proteins is essential to modulate crop salinity tolerance. This review gives a detailed overview of the membrane proteins involved in plant salinity stress highlighting the recent findings. Also, it discusses the role of solute transporters, accessory polypeptides, and proteins in salinity tolerance. Finally, some aspects of membrane proteins are discussed with potential applications to developing salt tolerance in crops.","PeriodicalId":50129,"journal":{"name":"Journal of Membrane Biology","volume":"256 2","pages":"109-124"},"PeriodicalIF":2.4,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9682050","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

Functional Potassium Channels in Macrophages. 巨噬细胞中的功能性钾通道。

IF 2.4 4区生物学

Journal of Membrane Biology Pub Date : 2023-04-01 DOI: 10.1007/s00232-022-00276-4

Qiaoyan Man, Zhe Gao, Kuihao Chen

{"title":"Functional Potassium Channels in Macrophages.","authors":"Qiaoyan Man, Zhe Gao, Kuihao Chen","doi":"10.1007/s00232-022-00276-4","DOIUrl":"https://doi.org/10.1007/s00232-022-00276-4","url":null,"abstract":"Macrophages are the predominant component of innate immunity, which is an important protective barrier of our body. Macrophages are present in all organs and tissues of the body, their main functions include immune surveillance, bacterial killing, tissue remodeling and repair, and clearance of cell debris. In addition, macrophages can present antigens to T cells and facilitate inflammatory response by releasing cytokines. Macrophages are of high concern due to their crucial roles in multiple physiological processes. In recent years, new advances are emerging after great efforts have been made to explore the mechanisms of macrophage activation. Ion channel is a class of multimeric transmembrane protein that allows specific ions to go through cell membrane. The flow of ions through ion channel between inside and outside of cell membrane is required for maintaining cell morphology and intracellular signal transduction. Expressions of various ion channels in macrophages have been detected. The roles of ion channels in macrophage activation are gradually caught attention. K+ channels are the most studied channels in immune system. However, very few of published papers reviewed the studies of K+ channels on macrophages. Here, we will review the four types of K+ channels that are expressed in macrophages: voltage-gated K+ channel, calcium-activated K+ channel, inwardly rectifying K+ channel and two-pore domain K+ channel.","PeriodicalId":50129,"journal":{"name":"Journal of Membrane Biology","volume":"256 2","pages":"175-187"},"PeriodicalIF":2.4,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9685028","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Chloride Channel-3 (ClC-3) Modifies the Trafficking of Leucine-Rich Repeat-Containing 8A (LRRC8A) Anion Channels. 氯离子通道-3（ClC-3）改变了含亮氨酸富重复序列 8A (LRRC8A) 阴离子通道的通路

IF 2.4 4区生物学

Journal of Membrane Biology Pub Date : 2023-04-01 Epub Date: 2022-11-02 DOI: 10.1007/s00232-022-00271-9

Ryan J Stark, Hong N Nguyen, Matthew K Bacon, Jeffrey C Rohrbough, Hyehun Choi, Fred S Lamb

{"title":"Chloride Channel-3 (ClC-3) Modifies the Trafficking of Leucine-Rich Repeat-Containing 8A (LRRC8A) Anion Channels.","authors":"Ryan J Stark, Hong N Nguyen, Matthew K Bacon, Jeffrey C Rohrbough, Hyehun Choi, Fred S Lamb","doi":"10.1007/s00232-022-00271-9","DOIUrl":"10.1007/s00232-022-00271-9","url":null,"abstract":"Chloride channel-3 (ClC-3) Cl-/H+ antiporters and leucine-rich repeat-containing 8 (LRRC8) family anion channels have both been associated with volume-regulated anion currents (VRACs). VRACs are often altered in ClC-3 null cells but are absent in LRRC8A null cells. To explore the relationship between ClC-3, LRRC8A, and VRAC we localized tagged proteins in human epithelial kidney (HEK293) cells using multimodal microscopy. Expression of ClC-3-GFP induced large multivesicular bodies (MVBs) with ClC-3 in the delimiting membrane. LRRC8A-RFP localized to the plasma membrane and to small cytoplasmic vesicles. Co-expression demonstrated co-localization in small, highly mobile cytoplasmic vesicles that associated with the early endosomal marker Rab5A. However, most of the small LRRC8A-positive vesicles were constrained within large MVBs with abundant ClC-3 in the delimiting membrane. Dominant negative (S34A) Rab5A prevented ClC-3 overexpression from creating enlarged MVBs, while constitutively active (Q79L) Rab5A enhanced this phenotype. Thus, ClC-3 and LRRC8A are endocytosed together but independently sorted in Rab5A MVBs. Subsequently, LRRC8A-labeled vesicles were sorted to MVBs labeled by Rab27A and B exosomal compartment markers, but not to Rab11 recycling endosomes. VRAC currents were significantly larger in ClC-3 null HEK293 cells. This work demonstrates dependence of LRRC8A trafficking on ClC-3 which may explain the association between ClC-3 and VRACs.","PeriodicalId":50129,"journal":{"name":"Journal of Membrane Biology","volume":"256 2","pages":"125-135"},"PeriodicalIF":2.4,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10085862/pdf/nihms-1879539.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10055104","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Role of Cholesterol and its Biosynthetic Precursors on Membrane Organization and Dynamics: A Fluorescence Approach. 胆固醇及其生物合成前体在膜组织和动力学中的作用:荧光方法。

IF 2.4 4区生物学

Journal of Membrane Biology Pub Date : 2023-04-01 DOI: 10.1007/s00232-023-00278-w

Sandeep Shrivastava, Yamuna Devi Paila, Amitabha Chattopadhyay

{"title":"Role of Cholesterol and its Biosynthetic Precursors on Membrane Organization and Dynamics: A Fluorescence Approach.","authors":"Sandeep Shrivastava, Yamuna Devi Paila, Amitabha Chattopadhyay","doi":"10.1007/s00232-023-00278-w","DOIUrl":"https://doi.org/10.1007/s00232-023-00278-w","url":null,"abstract":"Cholesterol is the most representative sterol present in membranes of higher eukaryotes, and is the end product of a long and multistep biosynthetic pathway. Lathosterol and zymosterol are biosynthetic precursors of cholesterol in Kandutsch-Russell and Bloch pathways, respectively. Lathosterol differs with cholesterol merely in the position of the double bond in the sterol ring, whereas zymosterol differs with cholesterol in position and number of double bonds. In this work, we have monitored the effect of cholesterol and its biosynthetic precursors (lathosterol and zymosterol) on membrane organization and dynamics in fluid and gel phase membranes. Toward this goal, we have utilized two fluorescent membrane probes, DPH and its cationic derivative TMA-DPH. Our results using these probes show that cholesterol and its biosynthetic precursors (lathosterol and zymosterol) exhibit similar trend in maintaining membrane organization and dynamics (as reported by fluorescence anisotropy and apparent rotational correlation time), in fluid phase POPC membranes. Notably, although lathosterol and zymosterol show similar trend in maintaining membrane organization and dynamics, the corresponding change for cholesterol is different in gel phase DPPC membranes. These results demonstrate that the position and number of double bonds in sterols is an important determinant in maintaining membrane physical properties. Our results assume significance since accumulation of precursors of cholesterol have been reported to be associated with severe pathological conditions.","PeriodicalId":50129,"journal":{"name":"Journal of Membrane Biology","volume":"256 2","pages":"189-197"},"PeriodicalIF":2.4,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9672870","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Surface Modification of Poly(tetrafluoroethylene) (PTFE) Membranes 聚四氟乙烯(PTFE)膜的表面改性

IF 2.4 4区生物学

Journal of Membrane Biology Pub Date : 2023-02-28 DOI: 10.14579/membrane_journal.2023.33.1.1

Jun Kyu Jang, Chaewon Youn, H. Park

引用次数: 0

Modeling of a Dynamic Membrane Filtration Process Using ANN and SVM to Predict the Permeate Flux 基于神经网络和支持向量机的动态膜过滤过程建模及渗透通量预测

IF 2.4 4区生物学

Journal of Membrane Biology Pub Date : 2023-02-28 DOI: 10.14579/membrane_journal.2023.33.1.34

Soufyane Ladeg, M. Moussaoui, M. Laidi, N. Moulai-Mostefa

引用次数: 0

CO2 Separation Performance of PEBAX Mixed Matrix Membrane Using PEI-GO@ZIF-8 as Filler PEI-GO@ZIF-8填料PEBAX混合基质膜的CO2分离性能

IF 2.4 4区生物学

Journal of Membrane Biology Pub Date : 2023-02-28 DOI: 10.14579/membrane_journal.2023.33.1.23

Eun. Yi, R. Hong, Hyun Kyung Lee

引用次数: 0

The Enhanced Electrochemical Performance of Lithium Metal Batteries through the Piezoelectric Protective Layer 利用压电保护层增强锂金属电池的电化学性能

IF 2.4 4区生物学

Journal of Membrane Biology Pub Date : 2023-02-28 DOI: 10.14579/membrane_journal.2023.33.1.13

Dae-Ung Park, W. Shin, H. Sohn

引用次数: 0

Perspective: Analysis of Conditions for High-efficiency/Eco-friendly Energy Production Devices for Smart Cities 视角:智慧城市高效/环保能源生产设备条件分析

IF 2.4 4区生物学

Journal of Membrane Biology Pub Date : 2023-02-28 DOI: 10.14579/membrane_journal.2023.33.1.46

S. Kang, Jeong Uk Kim

引用次数: 0

Caveolae Microdomains Mediate STAT5 Signaling Induced by Insulin in MCF-7 Breast Cancer Cells. MCF-7乳腺癌细胞中小泡微结构域介导胰岛素诱导的STAT5信号传导

IF 2.4 4区生物学

Journal of Membrane Biology Pub Date : 2023-02-01 DOI: 10.1007/s00232-022-00253-x

Rocio Castillo-Sanchez, Pedro Cortes-Reynosa, Mario Lopez-Perez, Alejandra Garcia-Hernandez, Eduardo Perez Salazar

{"title":"Caveolae Microdomains Mediate STAT5 Signaling Induced by Insulin in MCF-7 Breast Cancer Cells.","authors":"Rocio Castillo-Sanchez, Pedro Cortes-Reynosa, Mario Lopez-Perez, Alejandra Garcia-Hernandez, Eduardo Perez Salazar","doi":"10.1007/s00232-022-00253-x","DOIUrl":"https://doi.org/10.1007/s00232-022-00253-x","url":null,"abstract":"Caveolae are small plasma membrane invaginations constituted for membrane proteins namely caveolins and cytosolic proteins termed cavins, which can occupy up to 50% of the surface of mammalian cells. The caveolae have been involved with a variety of cellular processes including regulation of cellular signaling. Insulin is a hormone that mediates a variety of physiological processes through activation of insulin receptor (IR), which is a tyrosine kinase receptor expressed in all mammalian tissues. Insulin induces activation of signal transducers and activators of transcription (STAT) family members including STAT5. In this study, we demonstrate, for the first time, that insulin induces phosphorylation of STAT5 at tyrosine-694 (STAT5-Tyr(P)694), STAT5 nuclear accumulation and an increase in STAT5-DNA complex formation in MCF-7 breast cancer cells. Insulin also induces nuclear accumulation of STAT5-Tyr(P)694, caveolin-1, and IR in MCF-7 cells. STAT5 nuclear accumulation and the increase of STAT5-DNA complex formation require the integrity of caveolae and microtubule network. Moreover, insulin induces an increase and nuclear accumulation of STAT5-Tyr(P)694 in MDA-MB-231 breast cancer cells. In conclusion, results demonstrate that caveolae and microtubule network play an important role in STAT5-Tyr(P)694, STAT5 nuclear accumulation and STAT5-DNA complex formation induced by insulin in breast cancer cells.","PeriodicalId":50129,"journal":{"name":"Journal of Membrane Biology","volume":"256 1","pages":"79-90"},"PeriodicalIF":2.4,"publicationDate":"2023-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10641472","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0