Journal of Membrane Biology最新文献

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Role of Cholesterol and its Biosynthetic Precursors on Membrane Organization and Dynamics: A Fluorescence Approach. 胆固醇及其生物合成前体在膜组织和动力学中的作用:荧光方法。
IF 2.4 4区 生物学
Journal of Membrane Biology Pub Date : 2023-04-01 DOI: 10.1007/s00232-023-00278-w
Sandeep Shrivastava, Yamuna Devi Paila, Amitabha Chattopadhyay
{"title":"Role of Cholesterol and its Biosynthetic Precursors on Membrane Organization and Dynamics: A Fluorescence Approach.","authors":"Sandeep Shrivastava,&nbsp;Yamuna Devi Paila,&nbsp;Amitabha Chattopadhyay","doi":"10.1007/s00232-023-00278-w","DOIUrl":"https://doi.org/10.1007/s00232-023-00278-w","url":null,"abstract":"<p><p>Cholesterol is the most representative sterol present in membranes of higher eukaryotes, and is the end product of a long and multistep biosynthetic pathway. Lathosterol and zymosterol are biosynthetic precursors of cholesterol in Kandutsch-Russell and Bloch pathways, respectively. Lathosterol differs with cholesterol merely in the position of the double bond in the sterol ring, whereas zymosterol differs with cholesterol in position and number of double bonds. In this work, we have monitored the effect of cholesterol and its biosynthetic precursors (lathosterol and zymosterol) on membrane organization and dynamics in fluid and gel phase membranes. Toward this goal, we have utilized two fluorescent membrane probes, DPH and its cationic derivative TMA-DPH. Our results using these probes show that cholesterol and its biosynthetic precursors (lathosterol and zymosterol) exhibit similar trend in maintaining membrane organization and dynamics (as reported by fluorescence anisotropy and apparent rotational correlation time), in fluid phase POPC membranes. Notably, although lathosterol and zymosterol show similar trend in maintaining membrane organization and dynamics, the corresponding change for cholesterol is different in gel phase DPPC membranes. These results demonstrate that the position and number of double bonds in sterols is an important determinant in maintaining membrane physical properties. Our results assume significance since accumulation of precursors of cholesterol have been reported to be associated with severe pathological conditions.</p>","PeriodicalId":50129,"journal":{"name":"Journal of Membrane Biology","volume":null,"pages":null},"PeriodicalIF":2.4,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9672870","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Surface Modification of Poly(tetrafluoroethylene) (PTFE) Membranes 聚四氟乙烯(PTFE)膜的表面改性
IF 2.4 4区 生物学
Journal of Membrane Biology Pub Date : 2023-02-28 DOI: 10.14579/membrane_journal.2023.33.1.1
Jun Kyu Jang, Chaewon Youn, H. Park
{"title":"Surface Modification of Poly(tetrafluoroethylene) (PTFE) Membranes","authors":"Jun Kyu Jang, Chaewon Youn, H. Park","doi":"10.14579/membrane_journal.2023.33.1.1","DOIUrl":"https://doi.org/10.14579/membrane_journal.2023.33.1.1","url":null,"abstract":"","PeriodicalId":50129,"journal":{"name":"Journal of Membrane Biology","volume":null,"pages":null},"PeriodicalIF":2.4,"publicationDate":"2023-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86257000","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Modeling of a Dynamic Membrane Filtration Process Using ANN and SVM to Predict the Permeate Flux 基于神经网络和支持向量机的动态膜过滤过程建模及渗透通量预测
IF 2.4 4区 生物学
Journal of Membrane Biology Pub Date : 2023-02-28 DOI: 10.14579/membrane_journal.2023.33.1.34
Soufyane Ladeg, M. Moussaoui, M. Laidi, N. Moulai-Mostefa
{"title":"Modeling of a Dynamic Membrane Filtration Process Using ANN and SVM to Predict the Permeate Flux","authors":"Soufyane Ladeg, M. Moussaoui, M. Laidi, N. Moulai-Mostefa","doi":"10.14579/membrane_journal.2023.33.1.34","DOIUrl":"https://doi.org/10.14579/membrane_journal.2023.33.1.34","url":null,"abstract":"","PeriodicalId":50129,"journal":{"name":"Journal of Membrane Biology","volume":null,"pages":null},"PeriodicalIF":2.4,"publicationDate":"2023-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76598465","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
CO2 Separation Performance of PEBAX Mixed Matrix Membrane Using PEI-GO@ZIF-8 as Filler PEI-GO@ZIF-8填料PEBAX混合基质膜的CO2分离性能
IF 2.4 4区 生物学
Journal of Membrane Biology Pub Date : 2023-02-28 DOI: 10.14579/membrane_journal.2023.33.1.23
Eun. Yi, R. Hong, Hyun Kyung Lee
{"title":"CO2 Separation Performance of PEBAX Mixed Matrix Membrane Using PEI-GO@ZIF-8 as Filler","authors":"Eun. Yi, R. Hong, Hyun Kyung Lee","doi":"10.14579/membrane_journal.2023.33.1.23","DOIUrl":"https://doi.org/10.14579/membrane_journal.2023.33.1.23","url":null,"abstract":"","PeriodicalId":50129,"journal":{"name":"Journal of Membrane Biology","volume":null,"pages":null},"PeriodicalIF":2.4,"publicationDate":"2023-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80703395","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Enhanced Electrochemical Performance of Lithium Metal Batteries through the Piezoelectric Protective Layer 利用压电保护层增强锂金属电池的电化学性能
IF 2.4 4区 生物学
Journal of Membrane Biology Pub Date : 2023-02-28 DOI: 10.14579/membrane_journal.2023.33.1.13
Dae-Ung Park, W. Shin, H. Sohn
{"title":"The Enhanced Electrochemical Performance of Lithium Metal Batteries through the Piezoelectric Protective Layer","authors":"Dae-Ung Park, W. Shin, H. Sohn","doi":"10.14579/membrane_journal.2023.33.1.13","DOIUrl":"https://doi.org/10.14579/membrane_journal.2023.33.1.13","url":null,"abstract":"","PeriodicalId":50129,"journal":{"name":"Journal of Membrane Biology","volume":null,"pages":null},"PeriodicalIF":2.4,"publicationDate":"2023-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82574565","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Perspective: Analysis of Conditions for High-efficiency/Eco-friendly Energy Production Devices for Smart Cities 视角:智慧城市高效/环保能源生产设备条件分析
IF 2.4 4区 生物学
Journal of Membrane Biology Pub Date : 2023-02-28 DOI: 10.14579/membrane_journal.2023.33.1.46
S. Kang, Jeong Uk Kim
{"title":"Perspective: Analysis of Conditions for High-efficiency/Eco-friendly Energy Production Devices for Smart Cities","authors":"S. Kang, Jeong Uk Kim","doi":"10.14579/membrane_journal.2023.33.1.46","DOIUrl":"https://doi.org/10.14579/membrane_journal.2023.33.1.46","url":null,"abstract":"","PeriodicalId":50129,"journal":{"name":"Journal of Membrane Biology","volume":null,"pages":null},"PeriodicalIF":2.4,"publicationDate":"2023-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74708048","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Caveolae Microdomains Mediate STAT5 Signaling Induced by Insulin in MCF-7 Breast Cancer Cells. MCF-7乳腺癌细胞中小泡微结构域介导胰岛素诱导的STAT5信号传导
IF 2.4 4区 生物学
Journal of Membrane Biology Pub Date : 2023-02-01 DOI: 10.1007/s00232-022-00253-x
Rocio Castillo-Sanchez, Pedro Cortes-Reynosa, Mario Lopez-Perez, Alejandra Garcia-Hernandez, Eduardo Perez Salazar
{"title":"Caveolae Microdomains Mediate STAT5 Signaling Induced by Insulin in MCF-7 Breast Cancer Cells.","authors":"Rocio Castillo-Sanchez,&nbsp;Pedro Cortes-Reynosa,&nbsp;Mario Lopez-Perez,&nbsp;Alejandra Garcia-Hernandez,&nbsp;Eduardo Perez Salazar","doi":"10.1007/s00232-022-00253-x","DOIUrl":"https://doi.org/10.1007/s00232-022-00253-x","url":null,"abstract":"<p><p>Caveolae are small plasma membrane invaginations constituted for membrane proteins namely caveolins and cytosolic proteins termed cavins, which can occupy up to 50% of the surface of mammalian cells. The caveolae have been involved with a variety of cellular processes including regulation of cellular signaling. Insulin is a hormone that mediates a variety of physiological processes through activation of insulin receptor (IR), which is a tyrosine kinase receptor expressed in all mammalian tissues. Insulin induces activation of signal transducers and activators of transcription (STAT) family members including STAT5. In this study, we demonstrate, for the first time, that insulin induces phosphorylation of STAT5 at tyrosine-694 (STAT5-Tyr(P)<sup>694</sup>), STAT5 nuclear accumulation and an increase in STAT5-DNA complex formation in MCF-7 breast cancer cells. Insulin also induces nuclear accumulation of STAT5-Tyr(P)<sup>694</sup>, caveolin-1, and IR in MCF-7 cells. STAT5 nuclear accumulation and the increase of STAT5-DNA complex formation require the integrity of caveolae and microtubule network. Moreover, insulin induces an increase and nuclear accumulation of STAT5-Tyr(P)<sup>694</sup> in MDA-MB-231 breast cancer cells. In conclusion, results demonstrate that caveolae and microtubule network play an important role in STAT5-Tyr(P)<sup>694</sup>, STAT5 nuclear accumulation and STAT5-DNA complex formation induced by insulin in breast cancer cells.</p>","PeriodicalId":50129,"journal":{"name":"Journal of Membrane Biology","volume":null,"pages":null},"PeriodicalIF":2.4,"publicationDate":"2023-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10641472","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of Fluoxetine on the Surface Behavior of the Lipid Monolayers at Different Surface Pressures. 氟西汀对不同表面压力下脂质单分子膜表面行为的影响。
IF 2.4 4区 生物学
Journal of Membrane Biology Pub Date : 2023-02-01 DOI: 10.1007/s00232-022-00249-7
Bin Xie, Shumin Yang
{"title":"Effect of Fluoxetine on the Surface Behavior of the Lipid Monolayers at Different Surface Pressures.","authors":"Bin Xie,&nbsp;Shumin Yang","doi":"10.1007/s00232-022-00249-7","DOIUrl":"https://doi.org/10.1007/s00232-022-00249-7","url":null,"abstract":"<p><p>Fluoxetine (FLX), used in the clinic to treat depression, is a well-known cationic amphiphilic antidepressant. However, there is a lack of research on the effect of FLX on the surface behavior of lipid monolayers under different surface pressures. In this study, 1,2-dipalmitoyl-sn-glycero-3-phosphocholine/1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine/CHOL (DPPC/POPC/CHOL) monolayers were prepared via the Langmuir method, and FLX was added to these monolayers under various surface pressures. The effect of FLX on the surface behavior of DPPC/POPC/CHOL monolayers under various surface pressures was studied using a combination of surface pressure-area isotherms, compressibility modulus-surface pressure curves, and atomic force microscope (AFM). The results showed that the effect of FLX on the lipid monolayers was different under different surface pressures. The interaction between FLX and lipid molecules was weak under low surface pressures, and FLX could easily intercalate between the lipid molecules to inhibit monolayer phase transition. The interaction between FLX and lipid molecules was enhanced and FLX tended to self-aggregate to reduce the monolayer stability when the surface pressure was high. This study lays the foundation for further studies on the interaction between FLX and lipid monolayers.</p>","PeriodicalId":50129,"journal":{"name":"Journal of Membrane Biology","volume":null,"pages":null},"PeriodicalIF":2.4,"publicationDate":"2023-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10647658","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cellular Distribution Pattern of tjp1 (ZO-1) in Xenopus laevis Oocytes Heterologously Expressing Claudins. tjp1 (ZO-1)在异源表达claudin的非洲爪蟾卵母细胞中的细胞分布模式
IF 2.4 4区 生物学
Journal of Membrane Biology Pub Date : 2023-02-01 DOI: 10.1007/s00232-022-00251-z
Nora Brunner, Laura Stein, Salah Amasheh
{"title":"Cellular Distribution Pattern of tjp1 (ZO-1) in Xenopus laevis Oocytes Heterologously Expressing Claudins.","authors":"Nora Brunner,&nbsp;Laura Stein,&nbsp;Salah Amasheh","doi":"10.1007/s00232-022-00251-z","DOIUrl":"https://doi.org/10.1007/s00232-022-00251-z","url":null,"abstract":"<p><p>Epithelial barriers constitute a fundamental requirement in every organism, as they allow the separation of different environments and set boundaries against noxious and other adverse effectors. In many inflammatory and degenerative diseases, epithelial barrier function is impaired because of a disturbance of the paracellular seal. Recently, the Xenopus laevis oocyte has been established as a heterologous expression model for the analysis of transmembrane tight junction protein interactions and is currently considered to be a suitable screening model for barrier effectors. A prerequisite for this application is a physiological anchoring of claudins to the cytoskeleton via the major scaffolding protein tjp1 (tight junction protein 1, ZO-1). We have analyzed the oocyte model with regard to the interaction of heterologously expressed claudins and tjp1. Our experiments have revealed endogenous tjp1 expression in protein and mRNA analyses of unfertilized Xenopus laevis oocytes expressing human claudin 1 (CLDN1) to claudin 5 (CLDN5). The amphibian cell model can therefore be used for the analysis of claudin interactions.</p>","PeriodicalId":50129,"journal":{"name":"Journal of Membrane Biology","volume":null,"pages":null},"PeriodicalIF":2.4,"publicationDate":"2023-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9884258/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10655241","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Retraction Note: Correlation Between Composition of the Outer Layer and Phase Asymmetry for Vesicles Ruptured by Phospholipase D. 注:磷脂酶D破裂囊泡的外层组成与相不对称性的关系。
IF 2.4 4区 生物学
Journal of Membrane Biology Pub Date : 2023-02-01 DOI: 10.1007/s00232-022-00264-8
Jin-Won Park
{"title":"Retraction Note: Correlation Between Composition of the Outer Layer and Phase Asymmetry for Vesicles Ruptured by Phospholipase D.","authors":"Jin-Won Park","doi":"10.1007/s00232-022-00264-8","DOIUrl":"https://doi.org/10.1007/s00232-022-00264-8","url":null,"abstract":"","PeriodicalId":50129,"journal":{"name":"Journal of Membrane Biology","volume":null,"pages":null},"PeriodicalIF":2.4,"publicationDate":"2023-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10631393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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