Journal of Membrane Biology最新文献_第10页

The Enhanced Electrochemical Performance of Lithium Metal Batteries through the Piezoelectric Protective Layer 利用压电保护层增强锂金属电池的电化学性能

IF 2.4 4区生物学

Journal of Membrane Biology Pub Date : 2023-02-28 DOI: 10.14579/membrane_journal.2023.33.1.13

Dae-Ung Park, W. Shin, H. Sohn

引用次数: 0

Perspective: Analysis of Conditions for High-efficiency/Eco-friendly Energy Production Devices for Smart Cities 视角:智慧城市高效/环保能源生产设备条件分析

IF 2.4 4区生物学

Journal of Membrane Biology Pub Date : 2023-02-28 DOI: 10.14579/membrane_journal.2023.33.1.46

S. Kang, Jeong Uk Kim

引用次数: 0

Caveolae Microdomains Mediate STAT5 Signaling Induced by Insulin in MCF-7 Breast Cancer Cells. MCF-7乳腺癌细胞中小泡微结构域介导胰岛素诱导的STAT5信号传导

IF 2.4 4区生物学

Journal of Membrane Biology Pub Date : 2023-02-01 DOI: 10.1007/s00232-022-00253-x

Rocio Castillo-Sanchez, Pedro Cortes-Reynosa, Mario Lopez-Perez, Alejandra Garcia-Hernandez, Eduardo Perez Salazar

{"title":"Caveolae Microdomains Mediate STAT5 Signaling Induced by Insulin in MCF-7 Breast Cancer Cells.","authors":"Rocio Castillo-Sanchez, Pedro Cortes-Reynosa, Mario Lopez-Perez, Alejandra Garcia-Hernandez, Eduardo Perez Salazar","doi":"10.1007/s00232-022-00253-x","DOIUrl":"https://doi.org/10.1007/s00232-022-00253-x","url":null,"abstract":"Caveolae are small plasma membrane invaginations constituted for membrane proteins namely caveolins and cytosolic proteins termed cavins, which can occupy up to 50% of the surface of mammalian cells. The caveolae have been involved with a variety of cellular processes including regulation of cellular signaling. Insulin is a hormone that mediates a variety of physiological processes through activation of insulin receptor (IR), which is a tyrosine kinase receptor expressed in all mammalian tissues. Insulin induces activation of signal transducers and activators of transcription (STAT) family members including STAT5. In this study, we demonstrate, for the first time, that insulin induces phosphorylation of STAT5 at tyrosine-694 (STAT5-Tyr(P)694), STAT5 nuclear accumulation and an increase in STAT5-DNA complex formation in MCF-7 breast cancer cells. Insulin also induces nuclear accumulation of STAT5-Tyr(P)694, caveolin-1, and IR in MCF-7 cells. STAT5 nuclear accumulation and the increase of STAT5-DNA complex formation require the integrity of caveolae and microtubule network. Moreover, insulin induces an increase and nuclear accumulation of STAT5-Tyr(P)694 in MDA-MB-231 breast cancer cells. In conclusion, results demonstrate that caveolae and microtubule network play an important role in STAT5-Tyr(P)694, STAT5 nuclear accumulation and STAT5-DNA complex formation induced by insulin in breast cancer cells.","PeriodicalId":50129,"journal":{"name":"Journal of Membrane Biology","volume":"256 1","pages":"79-90"},"PeriodicalIF":2.4,"publicationDate":"2023-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10641472","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of Fluoxetine on the Surface Behavior of the Lipid Monolayers at Different Surface Pressures. 氟西汀对不同表面压力下脂质单分子膜表面行为的影响。

IF 2.4 4区生物学

Journal of Membrane Biology Pub Date : 2023-02-01 DOI: 10.1007/s00232-022-00249-7

Bin Xie, Shumin Yang

{"title":"Effect of Fluoxetine on the Surface Behavior of the Lipid Monolayers at Different Surface Pressures.","authors":"Bin Xie, Shumin Yang","doi":"10.1007/s00232-022-00249-7","DOIUrl":"https://doi.org/10.1007/s00232-022-00249-7","url":null,"abstract":"Fluoxetine (FLX), used in the clinic to treat depression, is a well-known cationic amphiphilic antidepressant. However, there is a lack of research on the effect of FLX on the surface behavior of lipid monolayers under different surface pressures. In this study, 1,2-dipalmitoyl-sn-glycero-3-phosphocholine/1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine/CHOL (DPPC/POPC/CHOL) monolayers were prepared via the Langmuir method, and FLX was added to these monolayers under various surface pressures. The effect of FLX on the surface behavior of DPPC/POPC/CHOL monolayers under various surface pressures was studied using a combination of surface pressure-area isotherms, compressibility modulus-surface pressure curves, and atomic force microscope (AFM). The results showed that the effect of FLX on the lipid monolayers was different under different surface pressures. The interaction between FLX and lipid molecules was weak under low surface pressures, and FLX could easily intercalate between the lipid molecules to inhibit monolayer phase transition. The interaction between FLX and lipid molecules was enhanced and FLX tended to self-aggregate to reduce the monolayer stability when the surface pressure was high. This study lays the foundation for further studies on the interaction between FLX and lipid monolayers.","PeriodicalId":50129,"journal":{"name":"Journal of Membrane Biology","volume":"256 1","pages":"43-50"},"PeriodicalIF":2.4,"publicationDate":"2023-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10647658","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cellular Distribution Pattern of tjp1 (ZO-1) in Xenopus laevis Oocytes Heterologously Expressing Claudins. tjp1 (ZO-1)在异源表达claudin的非洲爪蟾卵母细胞中的细胞分布模式

IF 2.4 4区生物学

Journal of Membrane Biology Pub Date : 2023-02-01 DOI: 10.1007/s00232-022-00251-z

Nora Brunner, Laura Stein, Salah Amasheh

{"title":"Cellular Distribution Pattern of tjp1 (ZO-1) in Xenopus laevis Oocytes Heterologously Expressing Claudins.","authors":"Nora Brunner, Laura Stein, Salah Amasheh","doi":"10.1007/s00232-022-00251-z","DOIUrl":"https://doi.org/10.1007/s00232-022-00251-z","url":null,"abstract":"Epithelial barriers constitute a fundamental requirement in every organism, as they allow the separation of different environments and set boundaries against noxious and other adverse effectors. In many inflammatory and degenerative diseases, epithelial barrier function is impaired because of a disturbance of the paracellular seal. Recently, the Xenopus laevis oocyte has been established as a heterologous expression model for the analysis of transmembrane tight junction protein interactions and is currently considered to be a suitable screening model for barrier effectors. A prerequisite for this application is a physiological anchoring of claudins to the cytoskeleton via the major scaffolding protein tjp1 (tight junction protein 1, ZO-1). We have analyzed the oocyte model with regard to the interaction of heterologously expressed claudins and tjp1. Our experiments have revealed endogenous tjp1 expression in protein and mRNA analyses of unfertilized Xenopus laevis oocytes expressing human claudin 1 (CLDN1) to claudin 5 (CLDN5). The amphibian cell model can therefore be used for the analysis of claudin interactions.","PeriodicalId":50129,"journal":{"name":"Journal of Membrane Biology","volume":"256 1","pages":"51-61"},"PeriodicalIF":2.4,"publicationDate":"2023-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9884258/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10655241","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

Retraction Note: Correlation Between Composition of the Outer Layer and Phase Asymmetry for Vesicles Ruptured by Phospholipase D. 注:磷脂酶D破裂囊泡的外层组成与相不对称性的关系。

IF 2.4 4区生物学

Journal of Membrane Biology Pub Date : 2023-02-01 DOI: 10.1007/s00232-022-00264-8

Jin-Won Park

引用次数: 0

Favourable Interfacial Characteristics of A2 Milk Protein Monolayer. A2 牛奶蛋白单层的有利界面特性

IF 2.3 4区生物学

Journal of Membrane Biology Pub Date : 2023-02-01 Epub Date: 2022-06-20 DOI: 10.1007/s00232-022-00248-8

Balaji S Dhopte, V N Lad

{"title":"Favourable Interfacial Characteristics of A2 Milk Protein Monolayer.","authors":"Balaji S Dhopte, V N Lad","doi":"10.1007/s00232-022-00248-8","DOIUrl":"10.1007/s00232-022-00248-8","url":null,"abstract":"Shielding of the specific body organ using the biocompatible material helps preventing direct exposure of that part to the foreign entities responsible for infections. Here we show the potential of the A2 milk protein recovered from the milk of cow from Indian origin for possible prevention of the direct exposure to other foreign molecules. We measured the surface pressure of the monolayers of different types of protein samples using Langmuir isotherm experiments. The surface pressure measurements for the monolayer of four types of protein macromolecules have been carried out using the Wilhelmy plate micro pressure sensor. We studied the self-organization of different protein macromolecules and their monolayer compression characteristics. The electrochemical behaviour is studied using electrochemical impedance spectroscopy. We found the highest surface pressure for the monolayer of A2 protein. Further, it is also found that A2 protein exhibited the highest surface activity amongst the other proteins. This property can be effectively used for making the envelope of the A2 protein surrounding the targeted entity.","PeriodicalId":50129,"journal":{"name":"Journal of Membrane Biology","volume":"256 1","pages":"35-41"},"PeriodicalIF":2.3,"publicationDate":"2023-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9208347/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10704321","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Aquaporins Display a Diversity in their Substrates. 水通道蛋白在其底物中表现出多样性。

IF 2.4 4区生物学

Journal of Membrane Biology Pub Date : 2023-02-01 DOI: 10.1007/s00232-022-00257-7

Ruchi Sachdeva, Pragya Priyadarshini, Sakshi Gupta

{"title":"Aquaporins Display a Diversity in their Substrates.","authors":"Ruchi Sachdeva, Pragya Priyadarshini, Sakshi Gupta","doi":"10.1007/s00232-022-00257-7","DOIUrl":"https://doi.org/10.1007/s00232-022-00257-7","url":null,"abstract":"Aquaporins constitute a family of transmembrane proteins that function to transport water and other small solutes across the cell membrane. Aquaporins family members are found in diverse life forms. Aquaporins share the common structural fold consisting of six transmembrane alpha helices with a central water-transporting channel. Four such monomers assemble together to form tetramers as their biological unit. Initially, aquaporins were discovered as water-transporting channels, but several studies supported their involvement in mediating the facilitated diffusion of different solutes. The so-called water channel is able to transport a variety of substrates ranging from a neutral molecule to a charged molecule or a small molecule to a bulky molecule or even a gas molecule. This article gives an overview of a diverse range of substrates conducted by aquaporin family members. Prime focus is on human aquaporins where aquaporins show a wide tissue distribution and substrate specificity leading to various physiological functions. This review also highlights the structural mechanisms leading to the transport of water and glycerol. More research is needed to understand how one common fold enables the aquaporins to transport an array of solutes.","PeriodicalId":50129,"journal":{"name":"Journal of Membrane Biology","volume":"256 1","pages":"1-23"},"PeriodicalIF":2.4,"publicationDate":"2023-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10648126","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Research Development on Exosome Separation Technology. 外泌体分离技术的研究进展。

IF 2.4 4区生物学

Journal of Membrane Biology Pub Date : 2023-02-01 DOI: 10.1007/s00232-022-00260-y

Wei-Ming Xu, Ao Li, Jia-Jun Chen, En-Jie Sun

{"title":"Research Development on Exosome Separation Technology.","authors":"Wei-Ming Xu, Ao Li, Jia-Jun Chen, En-Jie Sun","doi":"10.1007/s00232-022-00260-y","DOIUrl":"https://doi.org/10.1007/s00232-022-00260-y","url":null,"abstract":"Exosomes are special extracellular vesicles secreted by cells, which are of great significance in the basic research of life science and clinical application and has become a hot research field with rapid development in recent 10 years. Therefore, the isolation and separation of exosomes is particularly important for the research and application of exosomes. This paper aims to review the research progress of exosome isolation and separation methods in recent years, including ultracentrifugation, ultrafiltration, size‑exclusion chromatography, precipitation, immunomagnetic bead capture method, aptamer-based isolation, and isolation methods based on microfluidic technology. It is generally accepted that most of the existing methods have limitations, for example, ultracentrifugation is time-consuming and laborious, and immunomagnetic bead capture method and aptamer-based separation method have small sample processing capacity and high cost. As a result, we also introduce some common situations in which two or more methods are combined for use. Finally, the separation and isolation methods including all those presented in this review were compared and summarized.","PeriodicalId":50129,"journal":{"name":"Journal of Membrane Biology","volume":"256 1","pages":"25-34"},"PeriodicalIF":2.4,"publicationDate":"2023-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10650218","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 13

Correction: Role of Disulphide Bonds in Membrane Partitioning of a Viral Peptide. 修正:二硫键在病毒肽的膜分配中的作用。

IF 2.3 4区生物学

Journal of Membrane Biology Pub Date : 2023-02-01 DOI: 10.1007/s00232-022-00246-w

Samapan Sikdar, Manidipa Banerjee, Satyavani Vemparala

引用次数: 0