A. Tekin, Esra Özdil, M. Güleken, Reşat Ilişer, B. Bakım, J. Öncü, M. Çevik, B. Kuran
{"title":"Efficacy of High Frequency [10 Hz] Repetitive Transcranial Magnetic Stimulation of the Primary Motor Cortex in Patients with Fibromyalgia Syndrome: A Randomized, Double Blind, Sham-Controlled Trial","authors":"A. Tekin, Esra Özdil, M. Güleken, Reşat Ilişer, B. Bakım, J. Öncü, M. Çevik, B. Kuran","doi":"10.3109/10582452.2014.883042","DOIUrl":"https://doi.org/10.3109/10582452.2014.883042","url":null,"abstract":"Abstract Objectives: Repetitive transcranial magnetic stimulation [rTMS] of the cerebral cortex has been tested as a treatment tool for various neurological and psychiatric diseases and other painful disorders. Our objectives were to determine whether high-frequency rTMS applied to the primary motor cortex could decrease pain intensity and influence the quality of life in patients with fibromyalgia syndrome [FMS]. Design: Fifty two patients with FMS were randomized to real [n = 27] or sham [n = 25] treatment groups. Ten consecutive sessions of rTMS were given to each of the patients. All patients were evaluated with the Structured Clinical Interview from the Diagnostic and Statistical Manual of Mental Disorders before treatment. The level of pain and the mood status were assessed with a visual analog scale and the Montgomery Asberg Rating Scale, respectively. The Turkish version of the World Health Quality of Life-BREF instrument was used to evaluate the quality of life. Results: The decrease of pain scale scores was found to be significantly greater among the real rTMS group than among those in the sham group [p < 0.001]. Also the life quality physical subscale score improvement was significantly greater among those in the real rTMS therapy group than among those in the sham treatment group [p < 0.001]. A strong relationship was found betweeen the decrease of pain levels in the real rTMS treated patients and the life quality physical subscale score improvement [R2 = 0.419 and p < 0.001]. Conclusions: These findings suggest that high-frequency rTMS application to the primary motor cortex could have an analgesic effect. Therefore, rTMS may be an alternative therapeutic option in FMS.","PeriodicalId":50121,"journal":{"name":"Journal of Musculoskeletal Pain","volume":"30 1","pages":"20 - 26"},"PeriodicalIF":0.0,"publicationDate":"2014-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/10582452.2014.883042","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69500060","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Cover Art Commentary: Portrait of Adele Bloch-Bauer 1907by Gustav Klimt, Austrian, 1862–1918","authors":"Jon I. Russell","doi":"10.3109/10582452.2014.892556","DOIUrl":"https://doi.org/10.3109/10582452.2014.892556","url":null,"abstract":"","PeriodicalId":50121,"journal":{"name":"Journal of Musculoskeletal Pain","volume":"22 1","pages":"1 - 6"},"PeriodicalIF":0.0,"publicationDate":"2014-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/10582452.2014.892556","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69500178","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Efficacy of Ultrasound-facilitated Electrical Stimulation as an Adjunct to Exercise in Treating Chronic Neck and Shoulder Pain","authors":"Stanka Waschl, M. Morrissey, D. Rugelj","doi":"10.3109/10582452.2014.883009","DOIUrl":"https://doi.org/10.3109/10582452.2014.883009","url":null,"abstract":"Abstract Objective: To evaluate the effectiveness of ultrasound [US]-facilitated electrical stimulation [US/ES] of thoracic spine area trigger points [TrPs] as an adjunct to exercise/electrical stimulation therapy alone in patients with chronic neck and shoulders pain. Methods: Subjects were randomly allocated into two treatment groups; one group to receive classic treatment [exercise plus ES] and the second group in which the classic treatment was supplemented with US/ES treatment of TrPs in the upper trunk area on the painful side. Participants were tested for pain intensity using a visual analog scale [VAS] for pain, Box plots [Box], Margolis' scoring system [size of pain area], and pain self-efficacy questionnaire [PSEQ]. Results: Forty two male and female patients, aged 27 and 76 years, entered the study and 39 patients [34 women and five men; aged 51.8 ± 10 years] completed the study. The group that received the additional US/ES treatment exhibited greater improvements in pain intensity [Box, p = 0.05; VAS, p = 0.02] and size of the pain area, as measured with the Margolis scoring system [p = 0.019]. There were no differences between the treatment groups with respect to functional status, as measured by the PSEQ [p = 0.094]. Conclusion: The results showed that US/ES of TrPs as an adjunct to classical exercise/ES therapy can reduce the pain intensity in patients with chronic neck and shoulder pain.","PeriodicalId":50121,"journal":{"name":"Journal of Musculoskeletal Pain","volume":"22 1","pages":"78 - 88"},"PeriodicalIF":0.0,"publicationDate":"2014-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/10582452.2014.883009","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69499538","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
F. Morilla, L. Abasolo, M. Blanco, I. Méndez, J. Jover, B. Fernández-Gutiérrez
{"title":"Work Disability Related to Musculoskeletal Pain: A System Dynamics Approach","authors":"F. Morilla, L. Abasolo, M. Blanco, I. Méndez, J. Jover, B. Fernández-Gutiérrez","doi":"10.3109/10582452.2014.883007","DOIUrl":"https://doi.org/10.3109/10582452.2014.883007","url":null,"abstract":"Abstract Objective: To apply system dynamics methodology to study the evolution of temporary work disability in the context of pain-related musculoskeletal disorders [MSD-TWD]. Methods: Data were obtained from the MSD-TWD program records on 13 077 patients with acute disability [7805 in the control group [CG]; 5272 in the intervention group [IG]] who suffered 16 297 episodes of temporary work disability. Samples were randomized into two homogeneous sub-samples for validation purposes. The dynamic model developed with system dynamics methodology included 20 variables [five levels, seven rates, two auxiliary variables, six parameters], five differential equations, and eight algebraic equations. A sensitivity analysis of various scenarios was carried out. Results: Episodes were described according to their duration; short-term and long-term MSD-TWD. By tuning the model parameters, the actual survival curves of both groups in the two sub-samples were almost exactly reproduced. An explicit temporal expression of the survival curve was used in solving the equations of the dynamic model. The mean duration of short-term episodes was 18 days [d] in the CG and 14 d in the IG, while the mean duration of long-term episodes was 98 and 57 d, respectively. The conversion rate from short-term to long-term work disability was 7.3% in the CG compared with 3.5% in the IG. The model was cross-validated. Sensitivity analysis showed no overlap between the CG and IC curves. Conclusion: The dynamic model proposed is an excellent approach to the generic temporary work disability process, and is also able to explain the effects of intervention on the process.","PeriodicalId":50121,"journal":{"name":"Journal of Musculoskeletal Pain","volume":"22 1","pages":"51 - 61"},"PeriodicalIF":0.0,"publicationDate":"2014-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/10582452.2014.883007","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69499473","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
E. Adiguzel, S. Kesikburun, E. Yaşar, M. Taşkaynatan
{"title":"Major Perirectal Hematoma Complicating Sacroiliac Joint Injection","authors":"E. Adiguzel, S. Kesikburun, E. Yaşar, M. Taşkaynatan","doi":"10.3109/10582452.2014.883032","DOIUrl":"https://doi.org/10.3109/10582452.2014.883032","url":null,"abstract":"Abstract Background: Sacroiliac joint injection is both a way of confirming sacroiliac joint pain and a therapeutic method. Findings: A 40-year-old woman was presumptively diagnosed as having sacroiliac joint dysfunction and we performed a fluoroscopically guided sacroiliac joint injection. Many hours after the procedure, the patient developed severe buttock pain spreading to the posterior aspect of the femur on the left side. A pelvic magnetic resonance imaging revealed a 9 × 4 × 5.5 cm sized hematoma extending from the left obturator to the perirectal region. Conclusions: Because of anatomical variations, the practitioner should be alert to the risk of damaging vascular structures when performing therapeutic injections.","PeriodicalId":50121,"journal":{"name":"Journal of Musculoskeletal Pain","volume":"22 1","pages":"101 - 99"},"PeriodicalIF":0.0,"publicationDate":"2014-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/10582452.2014.883032","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69500314","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Selin Turan Turgut, A. Içağasioğlu, E. Selimoglu, Pinar Sahin, Y. Yumuşakhuylu, S. Murat
{"title":"Musculoskeletal Pain and Quality of Life in Obese Patients","authors":"Selin Turan Turgut, A. Içağasioğlu, E. Selimoglu, Pinar Sahin, Y. Yumuşakhuylu, S. Murat","doi":"10.3109/10582452.2014.883028","DOIUrl":"https://doi.org/10.3109/10582452.2014.883028","url":null,"abstract":"Abstract Objectives: The aim of this study is to investigate the impact of obesity on frequency and severity of musculoskeletal pain and quality of life. Methods: Demographic data of 230 patients that presented to the Physical Medicine and Rehabilitation Department because of musculoskeletal pain were acquired and analyzed. Patients were randomized into two groups according to body mass index [BMI] values: obese group [BMI ≥ 30 kg/m2] and normal-weighted group [BMI < 25 kg/m2]. Patients were asked for localization and duration of muskuloskeletal pain. Severity of pain was evaluated by using a visual analog scale. Information on difficulties of daily movements within the last month was obtained and quality of life was evaluated by using the Short-Form 36. Results: There was a statistically significant increase in frequency of neck pain [p = 0.049], shoulder pain [p = 0.001], elbow pain [p = 0.006], wrist and hand pain [p = 0.012], arm pain [p = 0.017], low back pain [p = 0.001], hip pain [p = 0.001], knee pain [p = 0.001], ankle-foot pain [p = 0.001], and leg pain [p = 0.001] in the obese group when compared with the normal-weighted group. There was a statistically significant increase in visual analog scale scores of the all body parts in the obese group when compared with in the normal-weighted group [p < 0.01]. There was a statistically significant difference between groups in difficulties of daily movements within last month [p < 0.01]. All the parameters of Short-Form 36 were found statistically significant lower in the obese group [p = 0.001]. Conclusions: Obesity is a multifactorial, chronic disease which causes many complications and pain on the musculoskeletal system. Difficulty of daily movements also decreases quality of life.","PeriodicalId":50121,"journal":{"name":"Journal of Musculoskeletal Pain","volume":"22 1","pages":"43 - 50"},"PeriodicalIF":0.0,"publicationDate":"2014-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/10582452.2014.883028","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69500208","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Natural Posture for Pain-Free Living: The Practice of Mindful Alignment","authors":"Michelle Layton","doi":"10.3109/10582452.2014.883043","DOIUrl":"https://doi.org/10.3109/10582452.2014.883043","url":null,"abstract":"","PeriodicalId":50121,"journal":{"name":"Journal of Musculoskeletal Pain","volume":"2 1","pages":"123 - 123"},"PeriodicalIF":0.0,"publicationDate":"2014-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/10582452.2014.883043","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69500071","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Primary Aldosteronism with Rhabdomyolysis: A Case Report","authors":"Lei Zhang, Hong-Jian Shi","doi":"10.3109/10582452.2014.890996","DOIUrl":"https://doi.org/10.3109/10582452.2014.890996","url":null,"abstract":"Abstract Background: Most cases of primary aldosteronisms present classic symptoms such as refractory hypertension, hypokalemia, elevated aldosterone and inhibition of renin, and angiotensin. However, some cases with rare clinical manifestations, such as skeletal muscle damage with elevated serum muscle enzymes [rhabdomyolysis], are more difficult to diagnose, and may result in a delayed clinical management. Findings: This paper reports a case of primary aldosteronism presented with rhadomyolysis due to severe hypokalemia. A 43-year-old male with a seven-year history of hypertension was admitted to the hospital with skeletal muscle weakness which he thought progressed rapidly over a period of four days, and resulted in quadriplegia for the preceding 12 hours. His laboratory tests showed hypokalemia [1.7 mmol/l] with elevations of serum creatine kinase and myocardial enzymes. An abdominal computed tomography revealed a 1.4 cm hypodense mass in the right adrenal gland, which suggested adrenocortical adenoma. He was treated with potassium and a laparoscopic adrenalectomy was performed. During one-year follow up, his blood pressure and serum potassium remained normal without the use of medications. Conclusions: The physicians should be aware of the potential for primary aldosteronism to cause severe hypokalemia and hypokalemic rhabdomyositis. That condition should be included in the differential diagnosis of muscle weakness.","PeriodicalId":50121,"journal":{"name":"Journal of Musculoskeletal Pain","volume":"22 1","pages":"102 - 105"},"PeriodicalIF":0.0,"publicationDate":"2014-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/10582452.2014.890996","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69500167","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Articular Cartilage Tissue Engineering: Development and Future: A Review","authors":"Zimin Wang (Jack), Jiang Peng","doi":"10.3109/10582452.2014.883017","DOIUrl":"https://doi.org/10.3109/10582452.2014.883017","url":null,"abstract":"Abstract Background: Articular cartilage is an avascular structure. Injured cartilage cannot self-repair, which results in joint pain and loss of mobility, eventually requiring articular cartilage replacement. Cartilage tissue engineering is a promising approach for regeneration and repair. Findings: In this paper, we reviewdc the normal structure and function of articular cartilage, the history of clinical techniques of cartilage tissue engineering, and two categories of cell sources for cartilage engineering. We also explored the environment of cell regeneration that includes scaffolds, growth factors, biomechanical stimulation in a three-dimensional bioreactor, and possible mechanical signal pathways. Conclusion: Successful cartilage tissue engineering relies on “energetic” cells, a number of growth factors, reliable scaffolds such as articular cartilage extracellular matrix oriented scaffolds, and joint-like mechanical stimuli.","PeriodicalId":50121,"journal":{"name":"Journal of Musculoskeletal Pain","volume":"22 1","pages":"68 - 77"},"PeriodicalIF":0.0,"publicationDate":"2014-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/10582452.2014.883017","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69499925","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Assessing the Perceptions of Fibromyalgia Syndrome in United States Among Academic Physicians and Medical Students: Where are We and Where are We Headed?","authors":"K. Amber, L. Brooks, J. Chee, T. Ference","doi":"10.3109/10582452.2014.883024","DOIUrl":"https://doi.org/10.3109/10582452.2014.883024","url":null,"abstract":"Abstract Objectives: Fibromyalgia syndrome [FMS] is a common condition, often diagnosed in the primary care setting, causing diffuse pain with additional somatic symptoms. Many physicians have questioned the existence of FMS due to an unclear pathophysiological origin and its overlap with other somatic syndromes. We sought to assess the perceptions of FMS among United States medical students and internal medicine and family medicine trained physicians working in an academic hospital. Methods: Residents and attendings working in a local teaching hospital were given questionnaires during undergraduate medical education sessions and academic conferences in internal medicine and family medicine. Medical students received surveys during small group sessions and through student mailboxes. Results: Seventy-two internal and family medicine trained physicians and 211 medical students were surveyed. In assessing whether FMS was primarily physiological or psychological in origin, 66% of physicians compared to only 29% of medical students [p < 0.001] chose a psychological etiology. Among physicians, women [82%] and American medical graduates [77%] were more likely to endorse a psychological mechanism than their counterparts [53% p < 0.010, 50% p = 0.022, respectively]. Additionally, when physicians were asked whether they believed FMS was an “actual illness,” 19% responded “no.” Conclusions: Fibromyalgia syndrome continues to be a controversial illness in the United States, especially when compared with values attained from international studies. Although current academic physicians appear to be skeptical of FMS’s existence or its potential physiological mechanisms, medical students are more likely to support a physiological mechanism.","PeriodicalId":50121,"journal":{"name":"Journal of Musculoskeletal Pain","volume":"22 1","pages":"13 - 19"},"PeriodicalIF":0.0,"publicationDate":"2014-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/10582452.2014.883024","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69500137","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}