Journal of Research in Medical Sciences最新文献

{"title":"The connection between hypertension and diabetes and their role in heart and kidney disease development.","authors":"Ali Ahmed Mohammed Hezam, Hanan Basheer Mohammed Shaghdar, Liying Chen","doi":"10.4103/jrms.jrms_470_23","DOIUrl":"10.4103/jrms.jrms_470_23","url":null,"abstract":"<p><p>Hypertension and diabetes are two common metabolic disorders that often coexist in the same individual. Their concurrence increases the risk of cardiovascular disease, renal dysfunction, and other complications. Cardiovascular disease is the primary cause of morbidity and mortality in individuals with diabetes, and hypertension further aggravates this condition. Interestingly, hypertension and diabetes share several common pathophysiological mechanisms including insulin resistance, vascular inflammation, endothelial dysfunction, obesity, and oxidative stress suggesting a cross-talk between these two conditions that could potentially contribute to the development of other human diseases. Effective management of diabetes should include a multifaceted approach that addresses not only glycemic control but also blood pressure (BP) and lipid control. Treatment plans should be individualized to each patient's needs and should involve a combination of lifestyle modifications and medications to achieve optimal control. With the availability of newer antidiabetic medications such as SGLT inhibitors and GLP1 receptor agonists, it is crucial to consider their potential to reduce BP, enhance kidney function, and lower the risk of cardiovascular diseases when initiating treatment for glycemic control. A more profound comprehension of the shared underlying mechanisms between these conditions could pave the way for the development of innovative therapeutic approaches to tackle them. Our review offers an in-depth analysis of the literature, providing a holistic view of the mechanisms underlying diabetes-hypertension comorbidity and its implications on heart and kidney diseases. The present article concludes by discussing current approaches for managing hypertensive diabetic patients to create a set of comprehensive individualized recommendations.</p>","PeriodicalId":50062,"journal":{"name":"Journal of Research in Medical Sciences","volume":null,"pages":null},"PeriodicalIF":1.6,"publicationDate":"2024-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11162087/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141297115","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Serum zinc levels in hemodialysis and peritoneal dialysis patients: A retrospective observational study","authors":"Masoud Mahmoudi, F. Moeinzadeh, A. Atapour, Shiva Seirafian, Zhina Azhir","doi":"10.4103/jrms.jrms_167_23","DOIUrl":"https://doi.org/10.4103/jrms.jrms_167_23","url":null,"abstract":"\u0000 \u0000 Zinc is vital for cellular functions, but kidney failure increases zinc deficiency risk. We compared zinc levels in hemodialysis (HD) and peritoneal dialysis (PD) patients in Isfahan, Iran.\u0000 \u0000 \u0000 \u0000 A retrospective study included 150 patients (75 PD and 75 HD). Serum zinc levels were assessed through photometry. Statistical analysis employed Chi-square, independent t-test, and correlation.\u0000 \u0000 \u0000 \u0000 Serum zinc was below normal in both groups (P < 0.01). HD patients had lower zinc levels (70.85 ± 7.68 mg/dL) compared to PD (75.04 ± 13.55 mg/dL, P = 0.021), remaining significant after adjusting for confounders (P = 0.011).\u0000 \u0000 \u0000 \u0000 Zinc levels in PD and HD patients are lower than in the general population, with HD patients having lower levels than PD patients.\u0000","PeriodicalId":50062,"journal":{"name":"Journal of Research in Medical Sciences","volume":null,"pages":null},"PeriodicalIF":1.6,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140399369","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Seroepidemiology of Toxoplasma gondii in diabetic patients type 2 by enzyme-linked immunosorbent assay method in Zabol City, 2017–2018","authors":"M. Dabirzadeh, Mojtaba Sargazi, Somayeh Bagheri","doi":"10.4103/jrms.jrms_49_23","DOIUrl":"https://doi.org/10.4103/jrms.jrms_49_23","url":null,"abstract":"\u0000 \u0000 Type 2 diabetes mellitus (T2DM) is prone to opportunistic infections, including toxoplasmosis, due to an immunodeficiency system. This study aimed to evaluate the serum of people with T2DM to determine the titer of anti-toxoplasma antibodies in patients and compare it with the control group.\u0000 \u0000 \u0000 \u0000 720 blood samples have been carried out between October and the end of January 2017 in Sistan, and Baluchestan provinces in southeastern Iran, of these, 360 samples were related to healthy individuals (control), and 360 samples were related to T2DM individuals. The immunoglobulin (Ig) M and IgG enzyme-linked immunosorbent assay methods have been used to detect toxoplasmosis. The data were analyzed using SPSS-19, Chi-square, and Fisher’s exact test to compare statistical parameters.\u0000 \u0000 \u0000 \u0000 In this cross-sectional study, out of 360 samples of T2DM by ELISA method, 60% samples in diabetic patients and 48.1% in control group were IgG positive (P < 0.05). Nearly 2.5% samples in diabetic patients and 0.3% in control group were IgM positive (P < 0.05).\u0000 \u0000 \u0000 \u0000 Anti-toxoplasma antibodies including IgG and IgM were higher in diabetic patient in comparison to control group.\u0000","PeriodicalId":50062,"journal":{"name":"Journal of Research in Medical Sciences","volume":null,"pages":null},"PeriodicalIF":1.6,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140407589","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Predictors of gastrointestinal bleeding in patients with acute coronary syndrome and the optimal duration of dual antiplatelet therapy","authors":"Yanyu Wang, Yingle Wu, Jingqiao Wang, Hengliang Zhang, L. Du, Ke Wang, Hongqiang Duan","doi":"10.4103/jrms.jrms_452_22","DOIUrl":"https://doi.org/10.4103/jrms.jrms_452_22","url":null,"abstract":"\u0000 \u0000 This study aims to estimate the risk factors of gastrointestinal (GI) bleeding in patients with acute coronary syndrome (ACS) and to evaluate the optimal duration of dual antiplatelet therapy (DAPT).\u0000 \u0000 \u0000 \u0000 We enrolled 1266 patients with ACS in a telephone follow-up program to determine whether any of the patients were hospitalized for GI bleeding. We collected baseline data, laboratory tests, electrocardiograms, and echocardiography covering all ACS patients. Multivariable regression was performed to adjust for confounders and predictors of GI bleeding. At the same time, the optimal duration of DAPT for ACS patients was evaluated.\u0000 \u0000 \u0000 \u0000 A total of 1061 ACS patients were included in the study. After 13–68 months, 48 patients (4.5%) were hospitalized for GI bleeding. The risk of GI bleeding was significantly increased in patients treated with DAPT for more than 18 months (hazard ratio 12.792, 5.607–29.185, P < 0.01). Receiver Operating Characteristic curve showed that the duration of DAPT using a cutoff of 14.5 months resulted in a sensitivity of 66.7% and a specificity of 77%.\u0000 \u0000 \u0000 \u0000 In patients with ACS, DAPT time are the main risk factors of GI bleeding. The optimal duration of DAPT is 14.5 months.\u0000","PeriodicalId":50062,"journal":{"name":"Journal of Research in Medical Sciences","volume":null,"pages":null},"PeriodicalIF":1.6,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140407054","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence of acute kidney injury following percutaneous nephrolithotomy","authors":"Saina Paymannejad, Mehdi Dehghani, Razieh Jafari Dehkordi, Shahram Taheri, Farid Shamlou, Hanieh Salehi, Reza Kazemi","doi":"10.4103/jrms.jrms_317_23","DOIUrl":"https://doi.org/10.4103/jrms.jrms_317_23","url":null,"abstract":"\u0000 \u0000 The objective is to evaluate the prevalence of acute kidney injury (AKI) as an early complication of the percutaneous nephrolithotomy (PCNL) procedure.\u0000 \u0000 \u0000 \u0000 From May 2022 to October 2022, we conducted a retrospective study on patients undergoing PCNL procedures in two of the tertiary medical centers affiliated with Isfahan University of Medical Sciences. Patients’ baseline characteristics, laboratory values, perioperative data, and stone features were documented. AKI was defined either as a ≥0.3 mg/dL increase in the serum creatinine level within 2 days, or a ≥1.5-fold increase in baseline serum creatinine level within 7 days after the operation. Laboratory values were measured 1 day before PCNL and daily thereafter until discharge. Patients were followed 1 week later to detect all of the possible cases of AKI.\u0000 \u0000 \u0000 \u0000 The final analysis was performed on 347 individuals. AKI developed in 16 (4.61%) cases. The two groups were comparable regarding age (P = 0.887), gender (P = 0.566), and underlying comorbidities including diabetes mellitus (P = 0.577) and hypertension (P = 0.383). The mean body mass index (BMI) (P < 0.001) and both frequency and severity of hydronephrosis (P < 0.001) were significantly different. A higher mean PCNL duration (P < 0.001), period of hospitalization (P < 0.001), and blood loss volume (P < 0.001) were observed in those who developed AKI. Overall, 56.3% (9) of patients in the AKI group and 2.7% (9) in the non-AKI group required the establishment of more than one access tract, during the procedure (P < 0.001). A lower preoperative hemoglobin level was observed in the AKI group (P < 0.001). Those with AKI had significantly larger stones (3.08 ± 0.46 vs. 2.41 ± 0.23 cm, P < 0.001) and higher Hounsfield units (P < 0.001). In addition, in the AKI group, most of the calculi (81.3%, 13) were of staghorn type, whereas in the non-AKI group, calculi were most frequently located in the middle calyx (30.2%, 100), (P < 0.001).\u0000 \u0000 \u0000 \u0000 The prevalence of post-PCNL AKI is approximately 4.61%. The mean BMI, preoperative hemoglobin level, PCNL duration, intraoperative blood loss volume, and hospitalization period were significantly higher among patients who developed AKI. Those with AKI had significantly larger stones with higher Hounsfield units and more frequently of staghorn type. The two groups were not statistically different regarding age, gender, and presence of comorbidities (hypertension and diabetes mellitus).\u0000","PeriodicalId":50062,"journal":{"name":"Journal of Research in Medical Sciences","volume":null,"pages":null},"PeriodicalIF":1.6,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140402228","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The psychometric properties of the Persian version of the Demoralization Scale (DS-II) in women with breast cancer","authors":"Aliakbar Foroughi, S. Khanjani, Mahboobeh Soleymani Moghadam, A. Parvizifard","doi":"10.4103/jrms.jrms_94_23","DOIUrl":"https://doi.org/10.4103/jrms.jrms_94_23","url":null,"abstract":"\u0000 \u0000 Demoralization is a syndrome of existential distress and despair in patients with cancer and other severe medical illnesses. The Demoralization Scale (DS-II) is self-administered and contains 16 items, and it has two factors: meaning and purpose and distress and coping ability.\u0000 \u0000 \u0000 \u0000 Women with breast cancer (240) completed the scales DS-II, positive and negative affect, state hope, patient health, and quality of life. Confirmatory factor analysis (CFA) and divergent and convergent validity were used to measure the construct validity of DS-II. CFA was chosen to check the fit of the two-factor model. Divergent and convergent validity were investigated using Pearson’s correlation test. The reliability of DS-II was evaluated by the internal consistency method. Cronbach’s alpha was used to calculate the internal consistency of the DS-II.\u0000 \u0000 \u0000 \u0000 The Cronbach’s alpha coefficient for the subscales of meaning and purpose, distress and coping ability, and the total score was obtained: 0.67, 0.72, and 0.81, respectively, indicated this scale’s good reliability. Furthermore, the Pearson correlation coefficient results showed the appropriate convergent validity and good divergent validity of the DS-II.\u0000 \u0000 \u0000 \u0000 The DS-II has sound psychometric properties and can be recommended as a reliable tool for assessing demoralization in women with breast cancer.\u0000","PeriodicalId":50062,"journal":{"name":"Journal of Research in Medical Sciences","volume":null,"pages":null},"PeriodicalIF":1.6,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140406585","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"First Iranian guidelines for the diagnosis, management, and treatment of hyperlipidemia in adults","authors":"Fahimeh Bagheri Kholenjani, S. Shahidi, G. Vaseghi, Vahid Ashoorion, N. Sarrafzadegan, M. Siavash, M. Heidarpour, S. Shahidi, Masoumeh Sadeghi, N. Mohammadifard, M. Jorjani, M. Mobarhan, Davood Shafie, Hossein Farshidi, F. Khorvash, Mojdeh Ghabaei, Zahra Teimouri-jervekani, M. Mortazavi, V. Hajhashemi, Neda Roshanravan, Leila Yazdanpanah, M. Davari, Behzad Fatemi, Elaheh Khorasani, Ramesh Hoseinkhani, E. Zarean, Alireza Ahmadi, M. Babadi, Ahmadreza Assareh, M. Shadmani, J. Kojuri, Farimah Shirani, M. Sanjari, F. Haghighatdoost, R. Hassannejad, Elham Hashemi, M. Moaddab, A. Gheisari, Bahar Dehghan, M. Naseri, N. Ghaemi, F. Noohi, A. Haghdoost, Amin salehi-Abargouei, Sara Beigrezaie, A. Doosti-Irani, Nahid Ramezani-Jolfaie, Bijan Eraj, M. Hashemipour, E. Nematipour, M. R. Kopaei","doi":"10.4103/jrms.jrms_318_23","DOIUrl":"https://doi.org/10.4103/jrms.jrms_318_23","url":null,"abstract":"This guideline is the first Iranian guideline developed for the diagnosis, management, and treatment of hyperlipidemia in adults. The members of the guideline developing group (GDG) selected 9 relevant clinical questions and provided recommendations or suggestions to answer them based on the latest scientific evidence. Recommendations include the low-density lipoprotein cholesterol (LDL-C) threshold for starting drug treatment in adults lacking comorbidities was determined to be over 190 mg/dL and the triglyceride (TG) threshold had to be >500 mg/dl. In addition to perform fasting lipid profile tests at the beginning and continuation of treatment, while it was suggested to perform cardiovascular diseases (CVDs) risk assessment using valid Iranian models. Some recommendations were also provided on lifestyle modification as the first therapeutic intervention. Statins were recommended as the first line of drug treatment to reduce LDL-C, and if its level was high despite the maximum allowed or maximum tolerated drug treatment, combined treatment with ezetimibe, proprotein convertase subtilisin/kexin type 9 inhibitors, or bile acid sequestrants was suggested. In adults with hypertriglyceridemia, pharmacotherapy with statin or fibrate was recommended. The target of drug therapy in adults with increased LDL-C without comorbidities and risk factors was considered an LDL-C level of <130 mg/dl, and in adults with increased TG without comorbidities and risk factors, TG levels of <200 mg/dl. In this guideline, specific recommendations and suggestions were provided for the subgroups of the general population, such as those with CVD, stroke, diabetes, chronic kidney disease, elderly, and women.","PeriodicalId":50062,"journal":{"name":"Journal of Research in Medical Sciences","volume":null,"pages":null},"PeriodicalIF":1.6,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140403790","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Investigating the effect of Aloe vera on the prevention and treatment of radiotherapy-induced oral mucositis in patients with head-and-neck cancer","authors":"Nadia Najafizade, Roya Mobini Dehkordi, S. Hemati","doi":"10.4103/jrms.jrms_115_23","DOIUrl":"https://doi.org/10.4103/jrms.jrms_115_23","url":null,"abstract":"\u0000 \u0000 Oral mucositis is one of the main complications of radiotherapy (RT) while treating head-and-neck cancers and can affect the patients’ treatment process and life. Therefore, this study evaluated the effect of Aloe vera on the prevention and treatment of radiotherapy-induced oral mucositis (RIOM) in patients with head-and-neck cancer.\u0000 \u0000 \u0000 \u0000 This was a double-blind clinical trial performed in 2019 on 75 patients with head-and-neck cancer. Patients were randomly assigned to two groups receiving gargles of 5 cc Aloe vera and the same dose of placebo mouthwash three times a day, respectively. Then, the incidence and severity of RIOM were evaluated and compared between the two groups over 6 weeks of RT.\u0000 \u0000 \u0000 \u0000 There was no significant difference between the two groups in terms of the severity of RIOM from the 1st to 3rd weeks of RT (P > 0.05). However, the severity of RIOM in the 4th, 5th, and 6th weeks of RT was significantly lower in the Aloe vera group compared with the placebo group (P < 0.05).\u0000 \u0000 \u0000 \u0000 According to the results of the present study, the long-term use of Aloe vera mouthwash can reduce the severity of RIOM.\u0000","PeriodicalId":50062,"journal":{"name":"Journal of Research in Medical Sciences","volume":null,"pages":null},"PeriodicalIF":1.6,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140405756","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"How much natural ventilation rate can suppress COVID-19 transmission in occupancy zones?","authors":"Amir Nejatian, Faranak Ebrahimian Sadabad, Farshad M Shirazi, Seyed Faraz Nejati, Samaneh Nakhaee, Omid Mehrpour","doi":"10.4103/jrms.jrms_796_22","DOIUrl":"10.4103/jrms.jrms_796_22","url":null,"abstract":"<p><strong>Background: </strong>Previous research has emphasized the importance of efficient ventilation in suppressing COVID-19 transmission in indoor spaces, yet suitable ventilation rates have not been suggested.</p><p><strong>Materials and methods: </strong>This study investigated the impacts of mechanical, natural, single-sided, cross-ventilation, and three mask types (homemade, surgical, N95) on COVID-19 spread across eight common indoor settings. Viral exposure was quantified using a mass balance calculation of inhaled viral particles, accounting for initial viral load, removal via ventilation, and mask filtration efficiency.</p><p><strong>Results: </strong>Results demonstrated that natural cross-ventilation significantly reduced viral load, decreasing from 10,000 to 0 viruses over 15 minutes in a 100 m2 space by providing ~1325 m3/h of outdoor air via two 0.6 m2 openings at 1.5 m/s wind speed. In contrast, single-sided ventilation only halved viral load at best.</p><p><strong>Conclusion: </strong>Natural cross-ventilation with masks effectively suppressed airborne viruses, lowering potential infections and disease transmission. The study recommends suitable ventilation rates to reduce COVID-19 infection risks in indoor spaces.</p>","PeriodicalId":50062,"journal":{"name":"Journal of Research in Medical Sciences","volume":null,"pages":null},"PeriodicalIF":1.6,"publicationDate":"2024-02-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10953753/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140177466","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effect of oral zinc on hemoglobin and dose of erythropoietin in hemodialysis patients.","authors":"Shiva Seirafian, Awat Feizi, Shahrzad Shahidi, Shirin Sadat Badri, Mohammad Hossein Rouhani, Pejman Pourazari Najafabadi, Elham Kabiri Naeini","doi":"10.4103/jrms.jrms_271_23","DOIUrl":"10.4103/jrms.jrms_271_23","url":null,"abstract":"<p><strong>Background: </strong>In hemodialysis (HD) patients, low serum zinc level could cause hyporesponsivity to erythropoiesis-stimulating agents and lead to anemia. This study investigated the effects of oral zinc supplements on the required dose of erythropoietin in patients undergoing HD.</p><p><strong>Materials and methods: </strong>In a double-blinded randomized trial, 76 HD patients were assigned to 2 groups of 38. One group (intervention) was treated with oral zinc supplements of 210 mg, daily for 6 months, and the other group (control) used placebo capsules for 6 months. The serum zinc level, hemoglobin level, and required dose of erythropoietin, albumin, ferritin, ferrous, and total iron-binding capacity were evaluated 3 and 6 months after intervention.</p><p><strong>Results: </strong>Repeated measures ANOVA did not show a significant increase in Hb level after 6 months of intervention (<i>P</i> = 0.28). However, the required dose of erythropoietin was decreased, but the changes were not statistically significant (<i>P</i> > 0.05). The changes in the other variables were not statistically significant.</p><p><strong>Conclusion: </strong>Oral zinc supplementation in HD patients could not increase hemoglobin level irrespective of their serum zinc level.</p>","PeriodicalId":50062,"journal":{"name":"Journal of Research in Medical Sciences","volume":null,"pages":null},"PeriodicalIF":1.6,"publicationDate":"2024-02-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10953733/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140177469","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}