Journal of Vestibular Research-Equilibrium & Orientation最新文献

{"title":"Clinical features and influencing factors of sleep disturbance in vestibular migraine patients: A multi-center cross-sectional study.","authors":"Qingchun Pan, Lei Wang, Bei Li, Kai Zou","doi":"10.1177/09574271261426885","DOIUrl":"10.1177/09574271261426885","url":null,"abstract":"<p><p>BackgroundVestibular migraine (VM) is frequently complicated by sleep disorders, potentially involving abnormalities in vestibular-brainstem neural pathways. This study aimed to analyze sleep characteristics and influencing factors in VM patients through a multicenter cross-sectional survey, explore associations with symptoms like vertigo and headache, and provide a basis for precise interventions.ObjectiveTo profile the sleep characteristics and clinical features of patients with vestibular migraine (VM), and to explore the influencing factors of sleep disturbance in VM patients.MethodsIn this multi-center cross-sectional study, we recruited VM patients who were treated in otolaryngology department and neurology department of 5 hospitals in Sichuan Province from June 2022 to June 2024 as experimental group (including two subgroups divided based on PSQI score: poor sleep quality (PSQI > 5) and good sleep quality (PSQI ≤ 5)), Meanwhile, the control group was composed of non-VM volunteers matching clinical characteristics of experimental group. After clinical data organization, participants were subjected to sleep quality assessment using the Pittsburgh Sleep Quality Index (PSQI). A multivariate Logistic regression was employed to outline factors influencing sleep disturbance in VM patients. In addition, Spearman correlation coefficient was used as a criterion to identify the correlation of sleep disturbance with headache, vertigo and hearing and other clinical features in VM patients.ResultsWith 530 VM patients included, 332 patients had poor sleep quality (PSQI > 5) (62.64%), 198 patients had good sleep quality (PSQI ≤ 5) (37.36%), and 50 patients were selected as the control. VM group had higher total and individual scores of PSQI (<i>p</i> < 0.05). PSQI in VM patients was correlated with VAS and DHI positively (r = 0.797, <i>p</i> < 0.05; r = 0.834, <i>p</i> < 0.05), but PSQI had no correlation with pure tone hearing (r = 0.324, <i>p</i> = 0.167). Moreover, female, age ≥60 years, living alone, duration of disease ≥3 months, motion sickness history, and HADS-A were independent influencing factors for VM patients with poor sleep quality (<i>p</i> < 0.05).ConclusionSleep disturbance is a major interfering factor in VM patients, and patients may experience more severe headache and vertigo when sleep disorder aggravates. VM patients who are female, ≥60 years old, live alone, have a disease course ≥3 months, have a history of motion sickness, and have anxiety should undergo sleep assessment to determine whether there is poor sleep quality, so as to provide a theoretical basis for VM intervention precisely.</p>","PeriodicalId":49960,"journal":{"name":"Journal of Vestibular Research-Equilibrium & Orientation","volume":" ","pages":"443-451"},"PeriodicalIF":1.2,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146208438","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Adaptation and validation of the Niigata PPPD questionnaire in Turkish: A clinical study.","authors":"Yuşa Başoğlu, Ayberk Aydın Tunç, Halil Berkay Saldırım","doi":"10.1177/09574271261437906","DOIUrl":"10.1177/09574271261437906","url":null,"abstract":"<p><p>ObjectiveThis study aimed to translate and cross-culturally adapt the Niigata Persistent Postural-Perceptual Dizziness Questionnaire (NPQ) into Turkish and evaluate its psychometric properties, including reliability, validity, and diagnostic accuracy, in Turkish-speaking patients with Persistent Postural-Perceptual Dizziness (PPPD).MethodsThis prospective case-control study included 114 participants: 36 PPPD patients, 40 with other vestibular disorders, and 38 healthy controls. Participants completed the Turkish version of the NPQ (T-NPQ) and the Dizziness Handicap Inventory (DHI). Internal consistency was assessed using Cronbach's alpha, and test-retest reliability was evaluated over 14-30-day interval. Construct validity was tested through confirmatory factor analysis (CFA) to test the hypothesized three-factor structure (Upright Posture/Walking, Movement, and Visual Stimulation), while convergent validity was examined by correlating T-NPQ scores with DHI scores. Diagnostic accuracy was assessed using Receiver Operating Characteristic (ROC) curve analysis.ResultsThe T-NPQ demonstrated excellent internal consistency (Cronbach's α = 0.919) and strong test-retest reliability (r = 0.832, <i>p</i> < .001). CFA supported the hypothesized three-factor structure and showed good model fit (χ²/df = 1.47, CFI = 0.964, RMSEA = 0.064). T-NPQ total scores strongly correlated with DHI total scores (r = 0.709, <i>p</i> < .001). The T-NPQ discriminated PPPD patients from other vestibular patients with an Area Under the Curve (AUC) of 0.746. The optimal cut-off score of 27.5 showed sensitivity of 86.1% and specificity of 57.5%.ConclusionThe Turkish version of the NPQ is a reliable and valid tool that may be useful for assessing symptom severity in PPPD patients. It has the potential to be effective for screening and measuring outcomes in clinical practice and research in Turkey.</p>","PeriodicalId":49960,"journal":{"name":"Journal of Vestibular Research-Equilibrium & Orientation","volume":" ","pages":"469-478"},"PeriodicalIF":1.2,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147500255","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Short-term vestibulo-ocular and postural effects of virtual reality in healthy young adults.","authors":"Enes Turkoglu, Busra Altin, Songul Aksoy","doi":"10.1177/09574271261494435","DOIUrl":"https://doi.org/10.1177/09574271261494435","url":null,"abstract":"<p><p>BackgroundVirtual reality can simulate the testing of cognitive, sensory, and motor skills using simulated environments. Eye stabilization is necessary to maintain visual acuity during rapid head movements; this is achieved through mechanisms such as the vestibulo-ocular reflex.ObjectiveThis study aimed to investigate the short-term effect of a passive, non-interactive virtual reality stimulus on dynamic visual acuity and postural sway in healthy young adults.Methods24 healthy young adults (9 males, 15 females) aged 20-39, with an average age of 26.08 ± 4.14 were included in the study. All participants underwent the Sensory Organization Test (SOT), Static Visual Acuity Test (SVAT), Perception Time Test (PTT), Dynamic Visual Acuity Test (DVAT), Gaze Stabilization Test (GST), and Visual Analogue Scale (VAS) to assess symptoms that may arise from virtual reality. These tests were repeated for all participants after the virtual reality experience, and completed on the same day.ResultsStatistically significant differences were obtained in the balance score of the SOT (COMP, mean decrease 2.29 points, 95% CI 0.49-4.10, <i>p</i> = 0.015, Cohen's d = 0.54) and the left-side GST (mean increase 24.7 ms, 95% CI -45.82 to -3.64, <i>p</i> = 0.024, Cohen's d = -0.52) in the pre/post virtual reality experience comparison. Virtual reality had no statistically significant effect on SOT conditions 1-6 individually (all <i>p</i> > 0.05), although CON6 and PTT were borderline (CON6: <i>p</i> = 0.095, r = 0.34; PTT: <i>p</i> = 0.053, r = 0.40). No statistically significant differences were found between pre- and post-treatment in PTT and DVAT (both <i>p</i> > 0.05).ConclusionIt has been demonstrated that a passive, non-interactive virtual reality stimulus may affect balance and gaze stabilization by increasing postural sway over a short, same-day time frame. Clinicians and researchers should be aware of these possible short-term effects when using similar VR-based paradigms for vestibular assessment and rehabilitation.</p>","PeriodicalId":49960,"journal":{"name":"Journal of Vestibular Research-Equilibrium & Orientation","volume":" ","pages":"9574271261494435"},"PeriodicalIF":1.2,"publicationDate":"2026-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149197436","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"mVOR: A digital health solution for remote assessment of gaze stability in unilateral vestibular dysfunction.","authors":"Adam Thompson-Harvey, Jesus D Gomez, Gia Oscherwitz, Sean Morgan, Ryan Stepp, Masud Rabbani, Naveen Bansal, Bradley Kesser, Sheikh Iqbal Ahamed, Joel A Goebel","doi":"10.1177/09574271261494420","DOIUrl":"https://doi.org/10.1177/09574271261494420","url":null,"abstract":"<p><p>ObjectiveTo evaluate whether a smartphone-based gaze stabilization test (mVOR) detects unilateral vestibular dysfunction (UVD) compared with computerized gaze stabilization testing.MethodsAdults with UVD (<i>n</i> = 18) and controls (<i>n</i> = 17) performed horizontal GST using mVOR and a commercially available computerized system. Outcomes were GST threshold (°/s) and lesioned vs non-lesioned differences.ResultsmVOR detected lower lesioned-side thresholds than non-lesioned (Δ -16.3°/s; <i>p</i> = 0.006) and lower lesioned-side values vs controls (100.9 ± 34.0 vs 142.9 ± 12.5°/s; <i>p</i> < 0.001). Computerized GST showed similar patterns (Δ -8.5°/s; <i>p</i> = 0.042; patients 84.0 ± 23.1 vs controls 111.2 ± 22.6°/s; <i>p</i> = 0.001).ConclusionsmVOR differentiated UVD from controls and lesioned from non-lesioned performance, with patterns comparable to those of computerized GST, supporting the feasibility of a scalable assessment.</p>","PeriodicalId":49960,"journal":{"name":"Journal of Vestibular Research-Equilibrium & Orientation","volume":" ","pages":"9574271261494420"},"PeriodicalIF":1.2,"publicationDate":"2026-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149185654","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"AI-enabled nystagmus analysis in vestibular assessment: Current evidence and future directions.","authors":"Reza Hoseinabadi","doi":"10.1177/09574271261496097","DOIUrl":"10.1177/09574271261496097","url":null,"abstract":"<p><p>Vestibular disorders are common, heterogeneous, and diagnostically challenging. Nystagmus is an important sign in vestibular assessment, but its interpretation can depend on clinician expertise and recording quality. This structured narrative review mapped current evidence on artificial intelligence (AI)-enabled nystagmus and eye-movement signal analysis in vestibular assessment, focusing on study characteristics, input data, AI tasks, model architectures, validation approaches, performance metrics, explainability, and clinical applicability. A structured PubMed search identified human studies that developed, validated, or evaluated machine-learning, deep-learning, or related computational methods for nystagmus analysis or vestibular diagnostic support. Fifteen studies were included, most published from 2021 onwards. The evidence was dominated by technical and early-stage model-development studies using VNG/VOG recordings, other eye-movement recordings, or derived features such as pupil trajectories, optical-flow maps, eye and head traces, and slow-phase velocity measures. Applications included nystagmus detection, pupil tracking and signal extraction, pattern or direction classification, quantification or localisation, and benign paroxysmal positional vertigo-related diagnostic classification. Deep-learning approaches, particularly convolutional neural networks and CNN-recurrent hybrid models, were commonly used. However, validation was mainly internal, performance reporting was heterogeneous, explainability was limited, and prospective workflow evaluation or routine clinical implementation was uncommon. AI-enabled nystagmus analysis shows promising clinical potential, particularly for VNG/VOG-based assessment and BPPV-related decision support. Translation into routine practice will require multicentre patient-level external validation, transparent reporting, interpretable outputs, standardised performance metrics, and prospective evaluation in real clinical pathways.</p>","PeriodicalId":49960,"journal":{"name":"Journal of Vestibular Research-Equilibrium & Orientation","volume":" ","pages":"9574271261496097"},"PeriodicalIF":1.2,"publicationDate":"2026-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149169050","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The metabolic matrix hypothesis of recurrent BPPV: Otoconia-otolithic membrane-endolymph fragility.","authors":"Pedro Stapleton-Garcia","doi":"10.1177/09574271261493213","DOIUrl":"https://doi.org/10.1177/09574271261493213","url":null,"abstract":"<p><p>Benign paroxysmal positional vertigo (BPPV) is treated as a purely mechanical disorder of displaced otoconia, yet this model alone does not readily account for spontaneous otoconia detachment, bilateral or multicanal disease, high recurrence rates, or the clustering of BPPV with systemic metabolic conditions in a subset of patients. This article proposes and structures a unifying mechanistic model-the Metabolic Matrix Hypothesis-linking systemic metabolic states to otoconial fragility, and derives testable predictions from it. It is a hypothesis-generating narrative and theoretical synthesis-not a systematic review or meta-analysis-of otoconial matrix biology, otolithic membrane anchoring, endolymph chemistry, and the dispersed clinical literature on metabolic risk factors for BPPV. Evidence supporting each proposed pathway is graded narratively as established clinical association, experimental or animal evidence, mechanistic inference, or speculative extension. In a biologically distinct subset of patients, recurrent idiopathic BPPV may represent the mechanical expression of a systemic metabolic fragility of the otoconia-otolithic membrane-endolymph unit. Vitamin D deficiency, estrogen withdrawal, osteoporosis, insulin resistance, oxidative stress, thyroid autoimmunity, and microvascular insufficiency may act as convergent entry points into impaired matrix resilience rather than independent risks. The model generates testable predictions and a clinically accessible metabolic evaluation for recurrent, bilateral, or multicanal disease, complementing repositioning maneuvers.</p>","PeriodicalId":49960,"journal":{"name":"Journal of Vestibular Research-Equilibrium & Orientation","volume":" ","pages":"9574271261493213"},"PeriodicalIF":1.2,"publicationDate":"2026-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149139215","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Vestibular symptom burden in hyperemesis gravidarum: A scale-based comparison with migraine and motion sickness.","authors":"Emel Uğur, Büşra Uludağ, Aysel Ozkaynak","doi":"10.1177/09574271261496103","DOIUrl":"https://doi.org/10.1177/09574271261496103","url":null,"abstract":"<p><p>PurposeMotion sickness (MS), visually induced motion sickness (VIMS), hyperemesis gravidarum (HG), and migraine share a spectrum of symptoms, including nausea, vomiting, dizziness, and heightened motion sensitivity. These commonalities suggest a potential shared neurophysiological basis involving vestibular and central nervous system mechanisms. This study aimed to evaluate the association between HG severity, MS susceptibility, VIMS susceptibility, and migraine-related symptom burden from a specialized vestibular perspective.MethodsThis cross-sectional study included 1010 women with a history of pregnancy. Data were collected via a comprehensive online questionnaire. The following assessment tools were utilized: Pregnancy-Unique Quantification of Emesis (PUQE-24), Motion Sickness Susceptibility Questionnaire (MSSQ), Visually Induced Motion Sickness Susceptibility Questionnaire (VIMSSQ), Migraine Disability Assessment Scale (MIDAS), and Headache Impact Test-6 (HIT-6). Nonparametric tests were used for group comparisons and correlations.ResultsParticipants were categorized as mild (44.5%), moderate (46.8%), or severe (8.7%) based on PUQE-24 scores. MSSQ, VIMSSQ, and HIT-6 scores differed significantly across HG severity groups (<i>p</i> < .05), whereas MIDAS scores did not (<i>p</i> = .055). Participants with severe HG symptoms demonstrated higher motion sickness and visually induced motion sickness susceptibility, as well as greater headache impact, compared with those reporting mild symptoms.ConclusionsGreater HG severity was accompanied by greater susceptibility to MS and VIMS, as well as a greater migraine-related symptom burden, although the observed associations were generally limited in magnitude. These findings suggest a possible role of vestibular sensitivity in pregnancy-related nausea and vomiting. However, further studies incorporating objective vestibular assessments are needed to clarify its clinical and physiological relevance.</p>","PeriodicalId":49960,"journal":{"name":"Journal of Vestibular Research-Equilibrium & Orientation","volume":" ","pages":"9574271261496103"},"PeriodicalIF":1.2,"publicationDate":"2026-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149129164","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Perception of the upright with tilted and rotating distractors in the fore- and background.","authors":"Anna J C Reuten, Jelte E Bos, Marco Otte, Jeroen B J Smeets","doi":"10.1177/09574271261492460","DOIUrl":"https://doi.org/10.1177/09574271261492460","url":null,"abstract":"<p><p>To perceive orientation relative to gravity, we combine sensory information with weights proportional to each cue's reliability. However, reliability alone does not fully determine a cue's weight. When asking observers to orient a visual rod parallel to the orientation of gravity in the presence of a static (tilted frame) or dynamic (rotating disc) distractor, some make much larger deviations into the direction of the distractor than others. This idiosyncratic weighting of cues for the perception of verticality has been explained by an individual trait: visual field dependence. However, it can be questioned whether the static and dynamic distractor effects are based on the same mechanism. If they are, changing the depth position of the distractor should induce a similar change in the weighting of static and dynamic visual cues for judging verticality. To test this, we placed the distractors at a different depth than the rod and reversed their depth order while keeping their retinal extent constant. This change influenced the two distractor effects differently: the effect of the disc was considerably larger when it was in the background, whereas the effect of the frame reduced. Furthermore, the effect of depth order did not show a significant correlation between the two distractors. Our findings thus suggest that static and dynamic distractor effects are based on at least partly different mechanisms, implying that there is not a single visual dependence.</p>","PeriodicalId":49960,"journal":{"name":"Journal of Vestibular Research-Equilibrium & Orientation","volume":" ","pages":"9574271261492460"},"PeriodicalIF":1.2,"publicationDate":"2026-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149076485","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cognitive functions in patients with vestibular migraine: Is there any difference from patients with migraine headaches only?","authors":"Birgül Dere, Hüseyin Nezih Özdemir, Hatice Eraslan Boz, Gülden Akdal, Neşe Çelebisoy, Figen Gökçay","doi":"10.1177/09574271261490480","DOIUrl":"https://doi.org/10.1177/09574271261490480","url":null,"abstract":"<p><p>BackgroundThe vestibular system contributes significantly to cognitive processes. Our study aims to detect the possible differences in cognitive function between patients with vestibular migraine (VM) and patients with migraine headaches only (MO).MethodsThis was a cross-sectional study. The participants took a number of tests during the same session: Mini Mental State Examination (MMSE), Stroop Test (ST), Digit Span Test (DST), Oktem Verbal Memory Process Test (OVMPT), Verbal and Nonverbal Cancellation Tests, Benton's Judgment Of Line Orientation Test (BJLOT), Rey-Osterrieth Complex Figure Test (ROCFT), Verbal Fluency Test (VFT), and Trail Making Test (TMT), in addition to Beck Anxiety Inventory (BAI) and Beck Depression Inventory (BDI).ResultsThere were 97 participants (VM = 34, MO = 31, HC = 32), matched for age, sex, and education. Both patient groups had higher BAI scores than controls (<i>p</i> < 0.001). Both patients with VM and patients with MO performed worse than healthy controls on the Stroop tasks, DSFT, and DSBT (<i>p</i> < 0.05 for all tasks, except Stroop Task 3 in the MO group), but no significant differences were observed between the VM and MO groups (<i>p</i> > 0.05). In the multivariable analyses, Stroop performance remained significantly worse in patients with VM, while DSFT and DSBT performance remained significantly worse in patients with MO (<i>p</i> < 0.05). In addition, both patient groups showed significantly worse performance on the TMT-B compared with controls (<i>p</i> < 0.05).ConclusionIn conclusion, our study showed that attention, working memory, and spatial cognitive functions were affected in patients with VM. However, no overall cognitive differences were identified between patients with VM and patients with MO.</p>","PeriodicalId":49960,"journal":{"name":"Journal of Vestibular Research-Equilibrium & Orientation","volume":" ","pages":"9574271261490480"},"PeriodicalIF":1.2,"publicationDate":"2026-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149070483","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Construct validity and responsiveness of the vertigo symptom scale-short form in patients with chronic dizziness.","authors":"Liv Heide Magnussen, Kjersti Thulin Wilhelmsen, Lene Kristiansen, Liv Inger Strand","doi":"10.1177/09574271261493208","DOIUrl":"https://doi.org/10.1177/09574271261493208","url":null,"abstract":"<p><p>BackgroundThe Vertigo Symptom Scale-Short Form (VSS-SF) is commonly used in clinical vestibular research but its ability to serve as an outcome measure has not been investigated.ObjectivesTo examine construct validity and responsiveness of the total scale and subscales addressing autonomic-anxiety (VSS-A) and vertigo-imbalance (VSS-V) in individuals with chronic dizziness.MethodsCross-sectional and longitudinal designs were applied. Predefined hypotheses were defined about the relationship between scores and change scores of the VSS-SF, VSS-V and VSS-A, assessing perceived symptoms of dizziness, and respective scores of other instruments assessing similar constructs, requiring 75% of hypothesis confirmed. The ability to discriminate between perceived improvement and not improvement by change scores was also examined.Major findingsThe VSS-SF demonstrated satisfactory construct validity with 75% of hypotheses confirmed, but not sufficient responsiveness with only 67% of hypotheses confirmed. Only the VSS-V showed adequate responsiveness to change by area under the ROC curve= 0.72. The optimal cut-off value to classify between improved and not improved patients was 4.5 on the 0-32-point scale.Conclusions<b>The VSS-SF and subscales demonstrated acceptable construct validity supporting its clinical use.</b> More studies on responsiveness are needed before a conclusion can be drawn regarding their ability to serve as an outcome measure.</p>","PeriodicalId":49960,"journal":{"name":"Journal of Vestibular Research-Equilibrium & Orientation","volume":" ","pages":"9574271261493208"},"PeriodicalIF":1.2,"publicationDate":"2026-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149065799","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}