The effect of using virtual reality on balance in people with persistent postural-perceptual dizziness: A randomized controlled trial.

IF 2.9 3区 医学 Q2 NEUROSCIENCES
Madlien M Al-Omari, Sawsan M Abuzaid, Hamzeh J Khair, Haidzir Manaf, Alia A Alghwiri
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Abstract

BackgroundPersistent postural-perceptual dizziness (PPPD) represents a relatively new vestibular diagnosis that has garnered attention within the medical community. Consequently, there is a pressing demand for efficacious management strategies.ObjectiveTo assess the comparative effectiveness of virtual reality (VR) versus vestibular rehabilitation therapy (VRT) in improving PPPD symptoms.MethodsWe randomly assigned a cohort of 42 individuals conclusively diagnosed with PPPD to two distinct groups. The experimental group included 21 participants who received a combination of VR and optokinetic stimulation in addition to VRT, while the control group, also made up of 21 individuals, only received optokinetic stimulation in conjunction with VRT. We administered the intervention sessions twice weekly over a span of 6 weeks, resulting in a total of 10-intervention sessions. Additionally, baseline, post-intervention, and follow-up assessments were conducted.ResultsOur analysis revealed that participants in both groups significantly improved with no significant differences between the groups. Individuals undergoing VR interventions demonstrated marked improvements across all of the assessed parameters including the primary outcome measure that were reduced from 41.55 (11.87) to 23.40 (14.17) (p<0.001). Moreover, participants in the control group also displayed notable enhancements in select outcome measures post-intervention including the primary outcome measure that were reduced from 43.60 (12.75) to 26.10 (16.25) (p = 0.001). All participants in both groups maintained significant improvement in the severity of PPPD after 1 year of the. However, the study cannot determine if this change was definitely from the treatment because there was no non-treatment control group.ConclusionsThe study found that the addition of VR to a well-structured VRT did not significantly improve clinical outcomes, indicating a need for further investigation into more effective approaches to yield meaningful clinical benefits. Moreover, adding a control group with no intervention would help revealing a real effect of the intervention.

使用虚拟现实对持续性体位知觉眩晕患者平衡的影响:一项随机对照试验。
背景:持续性体位知觉头晕(PPPD)是一种相对较新的前庭诊断,已引起医学界的关注。因此,迫切需要有效的管理策略。目的评价虚拟现实(VR)与前庭康复治疗(VRT)在改善PPPD症状中的比较效果。方法将42例确诊PPPD患者随机分为两组。实验组包括21名参与者,他们在接受VRT的同时接受VR和光动力刺激,而对照组也由21名参与者组成,他们只接受光动力刺激和VRT。我们每周进行两次干预,持续6周,总共进行了10次干预。此外,还进行了基线、干预后和随访评估。结果两组患者均有明显改善,两组间无显著差异。接受VR干预的个体在所有评估参数上都有显著改善,包括主要结果测量,从41.55(11.87)降至23.40 (14.17)(pp = 0.001)。治疗1年后,两组患者的PPPD严重程度均有显著改善。然而,该研究无法确定这种变化是否一定来自治疗,因为没有非治疗对照组。研究发现,在结构良好的VRT基础上添加VR并没有显著改善临床结果,这表明需要进一步研究更有效的方法来产生有意义的临床益处。此外,增加一个没有干预的对照组将有助于揭示干预的真实效果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
5.00
自引率
4.30%
发文量
66
审稿时长
>12 weeks
期刊介绍: Journal of Vestibular Research is a peer-reviewed journal that publishes experimental and observational studies, review papers, and theoretical papers based on current knowledge of the vestibular system. Subjects of the studies can include experimental animals, normal humans, and humans with vestibular or other related disorders. Study topics can include the following: Anatomy of the vestibular system, including vestibulo-ocular, vestibulo-spinal, and vestibulo-autonomic pathways Balance disorders Neurochemistry and neuropharmacology of balance, both at the systems and single neuron level Neurophysiology of balance, including the vestibular, ocular motor, autonomic, and postural control systems Psychophysics of spatial orientation Space and motion sickness Vestibular rehabilitation Vestibular-related human performance in various environments
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