Journal of VoicePub Date : 2025-09-01DOI: 10.1016/j.jvoice.2023.04.007
Saisree Ravi MD , Vanessa Lopez BA , Kathleen V. Carter MLIS , Stephanie A. Sharpe MLIS , Deepu George PhD , Barbara Ebersole MA , Michael Machiorlatti PhD , Nausheen Jamal MD
{"title":"Intersection of Mental Health and Dysphonia: A Scoping Review","authors":"Saisree Ravi MD , Vanessa Lopez BA , Kathleen V. Carter MLIS , Stephanie A. Sharpe MLIS , Deepu George PhD , Barbara Ebersole MA , Michael Machiorlatti PhD , Nausheen Jamal MD","doi":"10.1016/j.jvoice.2023.04.007","DOIUrl":"10.1016/j.jvoice.2023.04.007","url":null,"abstract":"<div><h3>Objective</h3><div><span>Previous research has indicated that voice disorders frequently co-occur with mental health disorders, which may influence voice </span>treatment seeking behavior and effectiveness. Our goal is to characterize the existing literature on the relationship between voice disorders and mental health and to investigate nuances related to mental health and voice disorder diagnosis.</div></div><div><h3>Data Sources</h3><div>Ovid MEDLINE, ProQuest PsycINFO, and Web of Science.</div></div><div><h3>Review Methods</h3><div>Using the PRISMA<span><span> protocol, a scoping review<span> was performed. Databases searched included: Ovid MEDLINE, ProQuest PsycINFO<span>, and Web of Science. Our inclusion criteria were all adults seen in an outpatient setting for voice and mental health disorders, excluding those with a prior history of </span></span></span>head and neck surgery<span>, cancers, radiation, or developmental anomalies, and certain mental health disorders. Results were screened by two independent screeners for inclusion. Data were then extracted and analyzed to present key findings and characteristics.</span></span></div></div><div><h3>Results</h3><div><span>A total of 156 articles, with publication dates ranging from 1938 to 2021, were included in the analysis, with females and teachers being the most described population groups. The most frequently studied laryngeal disorders<span> were dysphonia (</span></span><em>n</em><span> = 107, 68.6%), globus (</span><em>n</em><span> = 33, 21.2%), and dysphonia with globus (</span><em>n</em> = 16, 10.2%). The two most common mental health disorders found in the included studies were anxiety disorders (<em>n</em><span> = 123, 78.8%) and mood disorders (</span><em>n</em> = 111, 71.2%). The Voice Handicap Index was the most used tool to gather data on voice disorders (<em>n</em><span> = 36, 23.1%), while the Hospital Anxiety and Depression Scale was the most used tool to gather data on mental health disorders (</span><em>n</em> = 20, 12.8%). The populations studied within the included articles were predominately female and worked in educational occupations. Race and ethnicity was only reported for 10.2% of included articles (<em>n</em> = 16) and the most commonly studied race was White/Caucasian (<em>n</em> = 13, 8.3%).</div></div><div><h3>Conclusion</h3><div>Our scoping review of the current literature on mental health and voice disorders reveals an intersection between the conditions. The current literature represents change over time in terms of terminology that recognizes the patient's individualized experience of mental health and laryngeal conditions. However, there is still a great deal of homogeneity in the studied patient populations in terms of race and gender, with patterns and gaps that require further investigation.</div></div>","PeriodicalId":49954,"journal":{"name":"Journal of Voice","volume":"39 5","pages":"Pages 1418.e11-1418.e24"},"PeriodicalIF":2.4,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9484418","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Journal of VoicePub Date : 2025-09-01DOI: 10.1016/j.jvoice.2023.04.002
Jaromír Horáček , Vítězslav Bula , Vojtěch Radolf , Ahmed Geneid , Anne-Maria Laukkanen
{"title":"High-Speed Image Analysis Comparing Loading of Vocal Folds During Coughing and Phonation: A Case Study","authors":"Jaromír Horáček , Vítězslav Bula , Vojtěch Radolf , Ahmed Geneid , Anne-Maria Laukkanen","doi":"10.1016/j.jvoice.2023.04.002","DOIUrl":"10.1016/j.jvoice.2023.04.002","url":null,"abstract":"<div><h3>Purpose</h3><div>Coughing<span> is related to voice problems, since it involves firm glottal closure, fast glottal opening, and high subglottic pressure and flow rate. In this study, the glottal area variation and movements of laryngeal structures during coughing and phonation are compared.</span></div></div><div><h3>Methods</h3><div><span><span>High-speed laryngoscopy recordings were made of a normophonic male participant with a healthy </span>larynx<span> producing a neutral vowel and coughing. Oral air pressure was registered in a mouthpiece, through which an endoscope was inserted into the </span></span>pharynx<span><span>. Electroglottography, acoustic, and pressure signals were recorded simultaneously. The glottal width variation at the membranous and cartilaginous parts of the </span>glottis<span> was derived from the high-speed images, and the strong vibration of the false vocal folds was also registered.</span></span></div></div><div><h3>Results</h3><div><span>In coughing, compared to ordinary vowel phonation in nearly the same sound pressure level (93–94 dB</span><sub>6cm</sub>), the glottal width was 25% larger at the middle of the vocal folds, the maximum glottal opening velocity was 39% higher, and the maximum glottal width declination rate during glottal closing was up to three times higher. The maximum acceleration was 40% higher, and the maximum deceleration was 47% higher. Fundamental frequency <em>f<sub>0</sub></em> was the highest (ca. 400 Hz) at the beginning of the first phase of a typical coughing process. During the last part of the coughing process, <em>f<sub>0</sub></em> decreased from ca. 250 Hz to ca. 85 Hz at the phonation offset.</div></div><div><h3>Conclusions</h3><div>The remarkable increase in maximum glottal width declination rate implies much higher vocal fold loading in coughing compared to phonation.</div></div>","PeriodicalId":49954,"journal":{"name":"Journal of Voice","volume":"39 5","pages":"Pages 1419.e1-1419.e12"},"PeriodicalIF":2.4,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9813797","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Journal of VoicePub Date : 2025-09-01DOI: 10.1016/j.jvoice.2023.04.020
Jana Krtickova , Jan G. Svec , Jiri Haviger , Ketaki Vasant Phadke , Jakub Drsata , Lukas Skoloudik , Michal Homolac , Anna Svejdova , Jan Mejzlik , Lenka Hodacova , Viktor Chrobok
{"title":"Validation of the Czech Version of the Voice Handicap Index","authors":"Jana Krtickova , Jan G. Svec , Jiri Haviger , Ketaki Vasant Phadke , Jakub Drsata , Lukas Skoloudik , Michal Homolac , Anna Svejdova , Jan Mejzlik , Lenka Hodacova , Viktor Chrobok","doi":"10.1016/j.jvoice.2023.04.020","DOIUrl":"10.1016/j.jvoice.2023.04.020","url":null,"abstract":"<div><h3>Objective(s)</h3><div>The present study aims to evaluate the reliability and construct validity of the Czech version of the Voice Handicap Index (VHI-CZ) and determine the cut-off value to distinguish dysphonic patients from nondysphonic individuals.</div></div><div><h3>Study design</h3><div>Prospective study, Parallel group design.</div></div><div><h3>Methods</h3><div>The study investigated 100 adult patients with dysphonia<span>, divided into three groups based on the etiology of the voice problem (neurogenic, functional, and structural). Out of these, 25 patients were used for test-retest analysis, and 45 patients to determine the responsiveness to change. The control group consisted of 51 healthy subjects. All 151 individuals completed the VHI-CZ and were examined with the videolaryngostroboscopy. The internal consistency (Cronbach’s alpha), the test-retest reliability (Intra-class Correlation Coefficient, ICC), and the construct validity were analyzed and the normative cut-off value was determined.</span></div></div><div><h3>Results</h3><div>The internal consistency of the VHI-CZ was excellent (Cronbach α = 0.984), and test-retest reliability was also excellent (ICC = 0.95, <em>P</em> < 0.001). The correlation between the self-assessed severity of the voice disorder and the VHI-CZ score was strong (Spearman's ρ = 0.877, <em>P</em> < 0.001). The VHI scores differences between dysphonic and nondysphonic patients were statistically significant (Mann-Whitney <em>U</em> test, <em>P</em> < 0.001). The differences among the three etiological subgroups (neurogenic, functional, and structural) were also statistically significant (Kruskal-Wallis test, <em>P</em> < 0.001). Moreover, the differences in the VHI-CZ total scores between pretreatment and posttreatment were statistically significant (Wilcoxon test, <em>P</em> < 0.001). The cut-off score of 13 points was found, by the analysis of the Receiver Operating Characteristic (ROC, Youden Index), to be most suitable for preselecting dysphonic individuals.</div></div><div><h3>Conclusion</h3><div>The existing VHI-CZ showed excellent reliability and construct validity. The Czech VHI is a useful and valid monitoring tool for clinicians.</div></div>","PeriodicalId":49954,"journal":{"name":"Journal of Voice","volume":"39 5","pages":"Pages 1415.e7-1415.e14"},"PeriodicalIF":2.4,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10046994","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Journal of VoicePub Date : 2025-09-01DOI: 10.1016/j.jvoice.2023.03.002
Julianna Comstock Smeltzer , Sy Han Chiou , Adrianna C. Shembel
{"title":"Interoception, Voice Symptom Reporting, and Voice Disorders","authors":"Julianna Comstock Smeltzer , Sy Han Chiou , Adrianna C. Shembel","doi":"10.1016/j.jvoice.2023.03.002","DOIUrl":"10.1016/j.jvoice.2023.03.002","url":null,"abstract":"<div><h3>Objectives</h3><div><span>Interoception may play a role in how individuals perceive their voice disorder. The first objective of this study was to investigate relationships between interoception and voice disorder class (functional, structural, neurological). The second objective was to determine relationships between interoception and voice-related outcome measures between patients with functional voice and upper </span>airway disorders<span><span> and typical voice users. The third objective was to determine whether patients with primary muscle tension </span>dysphonia (a type of functional voice disorder) had different levels of interoceptive awareness than typical voice users.</span></div></div><div><h3>Study Design</h3><div>Prospective cohort study.</div></div><div><h3>Methods</h3><div><span>One hundred subjects with voice disorders completed the multidimensional assessment of interoceptive awareness-2 (MAIA-2). Voice diagnosis and singing experience were also acquired from each patient's medical chart. Voice handicap (VHI-10) and Part 1 of the vocal fatigue index (VFI-Part1) scores were obtained from patients diagnosed with functional voice and upper airway disorders. MAIA-2, VHI-10, VFI-Part1, and singing experience were also obtained from 25 typical voice users. Multivariable </span>linear regression models were used to assess the association between response variables and voice disorder class, adjusting for singing experience, gender, and age.</div></div><div><h3>Results</h3><div>There were no significant group differences between voice disorder class (functional, structural, neurological) after adjusting for multiple comparisons. Participants with functional voice and upper airway disorders who scored significantly higher on the VHI-10 and VFI-Part1 had lower <em>Attention Regulation</em> sub-scores on the MAIA-2 (<em>P's</em><span><0.05). Patients with primary muscle tension dysphonia scored significantly lower on the </span><em>Emotional Awareness</em> MAIA-2 subscale than typical voice users (<em>P</em>=0.005).</div></div><div><h3>Conclusion</h3><div>Patients with functional voice disorders with lower capabilities to attend to body sensations may score higher on voice-related patient-reported outcome measures, like the VHI-10 and VFI-Part1. Patients with primary muscle tension dysphonia may also have lower capabilities in processing their body sensations than typical voice users.</div></div>","PeriodicalId":49954,"journal":{"name":"Journal of Voice","volume":"39 5","pages":"Pages 1236-1245"},"PeriodicalIF":2.4,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9588555","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Journal of VoicePub Date : 2025-09-01DOI: 10.1016/j.jvoice.2023.02.027
Franziska Pelka, Maria Ensthaler, Olaf Wendler, Stefan Kniesburges, Anne Schützenberger, Marion Semmler
{"title":"Mechanical Parameters Based on High-Speed Videoendoscopy of the Vocal Folds in Patients With Ectodermal Dysplasia","authors":"Franziska Pelka, Maria Ensthaler, Olaf Wendler, Stefan Kniesburges, Anne Schützenberger, Marion Semmler","doi":"10.1016/j.jvoice.2023.02.027","DOIUrl":"10.1016/j.jvoice.2023.02.027","url":null,"abstract":"<div><h3>Objective</h3><div><span>Patients suffering from ectodermal dysplasia<span> (ED), which is an inherited disorder in the development of the ectodermal structures, have a significantly reduced expression of teeth, hair, sweat glands<span>, and salivary glands in the respiratory tract including the </span></span></span>larynx<span>. Previous studies within the framework of the present project showed a significantly reduced saliva production and an impairment of the acoustic outcome in ED patients compared to the control group. However, until now, no statistically significant difference between EDs and controls could be found regarding vocal fold<span> dynamics in the high-speed videoendoscopy (HSV) recordings using representative parameters on closure, symmetry, and periodicity. The aim of this study is to examine the role of tissue characteristics by means of objective mechanical parameters derived from HSV recordings.</span></span></div></div><div><h3>Methods</h3><div>This study includes 28 ED patients and 42 controls (no ED, healthy voice). The vocal fold oscillations were recorded by high-speed videoendoscopy (HSV@4kHz). Based on the dynamical measures of the glottal area waveform (GAW), objective glottal dynamic parameters associated with tissue properties like flexibility and stiffness were computed.</div></div><div><h3>Results</h3><div>The present evaluation displays a significant difference between male ED patients and male controls concerning the HSV-based mechanical parameters indicating reduced stiffness and increased deformability for the vocal folds of male ED patients. In contrast to strongly amplitude-dependent parameters, the primarily velocity-based parameters showed no statistically significant deviation.</div></div><div><h3>Conclusions</h3><div>The presented data provides the first promising indication toward the underlying causes on the laryngeal level leading to the voice conspicuities in ED patients. The significant difference concerning the mechanical parameters suggests a different composition of the extracellular matrix of the tissue of the vocal folds of ED patients compared to controls.</div></div>","PeriodicalId":49954,"journal":{"name":"Journal of Voice","volume":"39 5","pages":"Pages 1420.e1-1420.e8"},"PeriodicalIF":2.4,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9192643","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Health-related Quality of Life and Voice Handicap Index in Recovered COVID-19 Patients in Comparison to Healthy Subjects","authors":"Seyyedeh Maryam Khoddami , Samira Aghadoost , Mahshid Aghajanzadeh , Yasamin Molazeinal","doi":"10.1016/j.jvoice.2023.05.003","DOIUrl":"10.1016/j.jvoice.2023.05.003","url":null,"abstract":"<div><h3>Introduction</h3><div>COVID-19 has various long-lasting effects on different aspects of health and life. This study aimed to evaluate the general health and voice-related quality of life (QOL) and assess their correlation in patients with COVID-19 compared to healthy people.</div></div><div><h3>Study design</h3><div>This was a cross-sectional study.</div></div><div><h3>Methods</h3><div>Sixty-eight subjects (with a mean age of 40.07 ± 5.62 years) participated in two groups including 34 recovered-COVID-19 patients and 34 healthy subjects. All participants completed the Persian version of Short Form 36 (SF-36) and Voice Handicap Index (VHI). The patients were assessed two months after recovery when they were discharged from the hospital.</div></div><div><h3>Results</h3><div>The results showed the COVID-19 patients got significantly lower scores in all subcategories and two main components of SF-36 compared to the healthy group (<em>P</em> < 0.005). Also, the patients held significantly higher results in VHI and its subscales (<em>P</em> < 0.005). A significant correlation was observed between the physical and mental component summary (PCS and MCS) of SF-36 with a total score of VHI in the COVID-19 patients.</div></div><div><h3>Conclusion</h3><div>COVID-19 has negative consequences on various aspects of general health and voice-related QOL. Two months after recovery from COVID-19, the patients had the worst scores in all subscales of SF-36 and also, decreased physical, emotional, and functional voice-related QOL which reveals the persistent effect of COVID-19 even after recovery. The general health and voice-related QOL had a noticeable correlation in recovered COVID-19 patients that demonstrates the effect of voice quality in different aspects of life.</div></div>","PeriodicalId":49954,"journal":{"name":"Journal of Voice","volume":"39 5","pages":"Pages 1411.e11-1411.e18"},"PeriodicalIF":2.4,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9755933","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"One Year Outcomes and Longitudinal Changes in Voice Improvement With Single High Dose Intracordal Trafermin Injections for Age-Related Vocal Fold Atrophy","authors":"Tomohiro Hasegawa , Takeharu Kanazawa , Daigo Komazawa , Ujimoto Konomi , Mayu Hirosaki , Yusuke Watanabe","doi":"10.1016/j.jvoice.2023.03.017","DOIUrl":"10.1016/j.jvoice.2023.03.017","url":null,"abstract":"<div><h3>Objective</h3><div>Although intracordal trafermin injection has been performed in the treatment of age-related vocal fold atrophy, the effects of single high dose trafermin injections are unknown. In this study, we examined the 1 year outcomes and longitudinal changes in voice improvement with single high dose intracordal trafermin injections.</div></div><div><h3>Study Design</h3><div>Retrospective study with approval by our Ethics Committee.</div></div><div><h3>Methods</h3><div><span>The medical records of 34 patients who underwent single high dose (50ug per side) intracordal trafermin injections under </span>local anesthesia for vocal fold atrophy were retrospectively reviewed at 1 month pre-injection and 1 month, 6 months and 1 year post injection.</div></div><div><h3>Results</h3><div><span>Maximum phonation time (MPT), pitch range (PR), Japanese version of voice handicap index (VHI), grade of </span>GRBAS evaluation, and jitter% improved significantly at 1-year post-injection compared to 1-month pre-injection. MPT and PR improved as early as 1-month post-injection and continued to improve most at 1-year post-injection. VHI showed negative progression from 6-months to 1-year post-injection, during which time the speaking fundamental frequency (SFF) changed to the high pitch in men.</div></div><div><h3>Conclusions</h3><div>Single high dose intracordal trafermin injections can be expected to improve voice in the early post-injection period and to maintain its effect for 1 year. SFF may play a role in worsening VHI in men.</div></div><div><h3>Level of evidence</h3><div>level 4.</div></div>","PeriodicalId":49954,"journal":{"name":"Journal of Voice","volume":"39 5","pages":"Pages 1368-1376"},"PeriodicalIF":2.4,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9780308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Journal of VoicePub Date : 2025-09-01DOI: 10.1016/j.jvoice.2023.04.008
Bailey Balouch , Lauren E. Melley , Heather Yeakel , Parastou Azadeh Ranjbar , Jane Tong , Daniel Eichorn , Ghiath Alnouri , Matthew Brennan , Quynh Tran , Robert T. Sataloff
{"title":"Gluten Sensitivity Underlying Resistant “Laryngopharyngeal Reflux” Symptoms and Signs","authors":"Bailey Balouch , Lauren E. Melley , Heather Yeakel , Parastou Azadeh Ranjbar , Jane Tong , Daniel Eichorn , Ghiath Alnouri , Matthew Brennan , Quynh Tran , Robert T. Sataloff","doi":"10.1016/j.jvoice.2023.04.008","DOIUrl":"10.1016/j.jvoice.2023.04.008","url":null,"abstract":"<div><h3>Introduction</h3><div><span>Laryngopharyngeal reflux<span> (LPR) is one of the most common conditions encountered in otolaryngology. </span></span>Gluten sensitivity<span> may mimic the signs and symptoms<span><span> of LPR or act as an aggravating cofactor with LPR. Gluten sensitivity and </span>food intolerance also have been implicated as conditions that may be associated specifically with LPR symptoms and signs resistant to traditional medical treatment. Medical management of LPR may be insufficient to control symptoms and laryngeal signs of reflux, constituting resistant LPR. Eliminating gluten from the diet could provide symptomatic relief to patients with gluten sensitivity and LPR that is not controlled adequately by current regimens. The purpose of our study was to investigate the relationship between gluten sensitivity and LPR. We aimed to evaluate reflux finding score (RFS) improvement following elimination of gluten from the diet in patients with resistant LPR who had positive blood tests associated with gluten sensitivity. Symptom improvement was also assessed following dietary gluten elimination. Lastly, we aimed to identify predictors for a positive response to a gluten-free diet.</span></span></div></div><div><h3>Methods</h3><div>Adult patients who underwent gluten sensitivity testing for treatment-resistant LPR symptoms and/or signs were included. Patients with ≥1 positive test were advised to begin a therapeutic trial of a gluten-free diet. Subjects who chose not to trial a gluten-free diet or tested negative for gluten sensitivity markers served as controls. RFS was the primary outcome measure.</div></div><div><h3>Results</h3><div>One hundred ninety-seven patients were included; 81 trialed a gluten-free diet. Subjects who trialed the gluten-free diet were significantly more likely to demonstrate objective improvement in RFS (77.14% vs 43.88%), and report subjective improvement (55.41% vs 25.77%) than those who did not. RFS had decreased significantly from baseline at 1-3, 3-6, 6-12, and >12-month interval follow-up examinations in subjects who trialed a gluten-free diet. Comparison between subjects who trialed the gluten-free diet, tested positive for a gluten sensitivity marker but did not trial the gluten-free diet, and subjects who were negative for all gluten sensitivity markers revealed that a gluten-free diet was associated with a significantly greater percent improvement in RFS compared to controls at 1-3, 6-12, and >12-months.</div></div><div><h3>Conclusion</h3><div>Gluten sensitivity can mimic or aggravate LPR. A gluten-free diet should be considered for patients with resistant LPR, especially if blood test abnormalities that suggest gluten sensitivity are identified. The diet should be maintained for a minimum of three months to demonstrate objective improvement using RFS.</div></div>","PeriodicalId":49954,"journal":{"name":"Journal of Voice","volume":"39 5","pages":"Pages 1346-1352"},"PeriodicalIF":2.4,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10209918","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Journal of VoicePub Date : 2025-09-01DOI: 10.1016/j.jvoice.2023.02.031
Beata Miaśkiewicz , Elżbieta Gos , Małgorzata Dębińska , Aleksandra Panasiewicz-Wosik , Dorota Kapustka , Agata Szkiełkowska , Henryk Skarżynski
{"title":"Validation of the Polish Version of Voice Handicap Index-10","authors":"Beata Miaśkiewicz , Elżbieta Gos , Małgorzata Dębińska , Aleksandra Panasiewicz-Wosik , Dorota Kapustka , Agata Szkiełkowska , Henryk Skarżynski","doi":"10.1016/j.jvoice.2023.02.031","DOIUrl":"10.1016/j.jvoice.2023.02.031","url":null,"abstract":"<div><h3>Purpose</h3><div>The aim of this study was to adapt and evaluate the psychometric properties of the Polish version of the VHI-10.</div></div><div><h3>Methods</h3><div>We enrolled 183 subjects—118 patients with voice disorders and 65 without voice disorders.</div></div><div><h3>Results</h3><div>All items were correlated with each other and were strongly correlated with the total score (<em>rho</em> ≥ 0.70), the only exception being item five (<em>rho</em><span> = 0.56). Internal consistency<span> was very high, with Cronbach's alpha = 0.92. There was a statistically significant difference between patients with voice disorders and healthy controls in terms of VHI-10 global score (</span></span><em>U</em> = 251.0; <em>P</em><span> < 0.001). There was a statistically significant negative correlation between mean phonation time (MPT) and VHI-10 (</span><em>rho</em> = −0.30; <em>P</em> < 0.01). Only the amplitude perturbation quotient (APQ) was correlated positively with the global score (<em>rho</em> = 0.22; <em>P</em> = 0.020). There were statistically significant and positive correlations between VHI-10 scores and GRBAS evaluation. Correlations between global scores of VHI-30 and VHI-10, and between VHI-30 subscales and the corresponding items from VHI-10, were very strong (respectively 0.97 and 0.89–0.94). In the patient group, there was high test–retest reproducibility (intraclass correlation = 0.91). A cut-off value of 8.5 points was estimated.</div></div><div><h3>Conclusion</h3><div>The Polish version of VHI-10 showed excellent internal consistency, good test–retest reproducibility, and had clinical validity. It is a useful brief tool for self-reported evaluation and reliable assessment of patients with voice disorders.</div></div>","PeriodicalId":49954,"journal":{"name":"Journal of Voice","volume":"39 5","pages":"Pages 1417.e1-1417.e9"},"PeriodicalIF":2.4,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9453886","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Journal of VoicePub Date : 2025-09-01DOI: 10.1016/j.jvoice.2023.05.006
Noah Millman , Benjamin van der Woerd , Lauren Timmons Sund , Michael Johns
{"title":"Cannabinoid Use in the Treatment of Laryngeal Dystonia and Vocal Tremor: A Pilot Investigation","authors":"Noah Millman , Benjamin van der Woerd , Lauren Timmons Sund , Michael Johns","doi":"10.1016/j.jvoice.2023.05.006","DOIUrl":"10.1016/j.jvoice.2023.05.006","url":null,"abstract":"<div><h3>Objectives/hypothesis</h3><div>Laryngeal dystonia<span> and vocal tremor can be debilitating conditions with suboptimal treatment options. Botulinum toxin<span> chemodenervation is typically the first-line treatment and is considered the gold standard. However, patient response to botulinum toxin varies widely. There is anecdotal evidence for the use of cannabinoids<span> in treating laryngeal dystonia with a scarcity of research investigating this potential treatment option. The primary objective of this study is to survey patients with laryngeal dystonia and vocal tremor to gauge how some people are using cannabinoids to treat their condition and to ascertain patient perceptions of cannabinoid effectiveness.</span></span></span></div></div><div><h3>Study Design</h3><div>This is a cross-sectional survey study.</div></div><div><h3>Methods</h3><div>An eight-question anonymous survey was distributed to people with abductor spasmodic dysphonia<span> adductor spasmodic dysphonia<span>, vocal tremor, muscle tension dysphonia, and mixed laryngeal dystonia via the Dysphonia International (formerly National Spasmodic Dysphonia Association) email listserv.</span></span></div></div><div><h3>Results</h3><div>158 responses: 25 males and 133 females, (mean [range] age, 64.9 [22–95] years). 53.8% of participants had tried cannabinoids for the purposes of treating their condition at some point, with 52.9% of this subset actively using cannabis as part of their treatment. Most participants who have used cannabinoids as a treatment rank their effectiveness as somewhat effective (42.4%) or ineffective (45.9%). Participants cited a reduction in voice strain and anxiety as reasons for cannabinoid effectiveness.</div></div><div><h3>Conclusions</h3><div>People with laryngeal dystonia and/or vocal tremor currently use or have tried using cannabinoids as a treatment for their condition. Cannabinoids were better received as a supplementary treatment than as a stand-alone treatment.</div></div>","PeriodicalId":49954,"journal":{"name":"Journal of Voice","volume":"39 5","pages":"Pages 1313-1320"},"PeriodicalIF":2.4,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9624736","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}