Korean Journal of Pathology最新文献_第9页

Benign Indolent CD56-Positive NK-Cell Lymphoproliferative Lesion Involving Gastrointestinal Tract in an Adolescent. 一例青少年胃肠道良性惰性cd56阳性nk细胞增生性病变。

Korean Journal of Pathology Pub Date : 2014-02-01 Epub Date: 2014-02-25 DOI: 10.4132/KoreanJPathol.2014.48.1.73

Jaemoon Koh, Heounjeong Go, Won Ae Lee, Yoon Kyung Jeon

{"title":"Benign Indolent CD56-Positive NK-Cell Lymphoproliferative Lesion Involving Gastrointestinal Tract in an Adolescent.","authors":"Jaemoon Koh, Heounjeong Go, Won Ae Lee, Yoon Kyung Jeon","doi":"10.4132/KoreanJPathol.2014.48.1.73","DOIUrl":"https://doi.org/10.4132/KoreanJPathol.2014.48.1.73","url":null,"abstract":"The gastrointestinal (GI) tract is the most common site of primary extranodal lymphomas. Although B-cell non-Hodgkin lymphomas account for the majority of GI lymphoma, T- or natural killer (NK)-cell lymphomas, including peripheral T-cell lymphoma, enteropathy-associated T-cell lymphoma (EATL), extranodal NK/T-cell lymphoma, and anaplastic large cell lymphoma, also involves the GI tract.1,2 T- or NK-cell lymphomas are an aggressive disease typically managed with systemic chemotherapy or radiotherapy; however, pathologic diagnosis of intestinal T- or NK-cell lymphoma based on a small biopsy specimen is often challenging. \u0000 \u0000Recently, a unique clinicopathologic entity involving GI tract and characterized by an atypical proliferation of NK-cells has been described under the term \"NK-cell enteropathy\" or \"lymphomatoid gastropathy.\"3,4 All afflicted patients were adults and had no history of celiac disease. Endoscopic findings were variable with superficial ulceration, edema, hemorrhage, and the presence of small, elevated lesions from stomach to colon. Histologically, the lamina propria of the mucosa was infiltrated by atypical NK-cells. Tests for Epstein-Barr virus (EBV) were negative, and T-cell monoclonality was not detected. Although these lesions can pathologically mimic intestinal NK- or T-cell lymphoma to the extent that some patients were diagnosed with lymphoma, all patients had a benign clinical course. Thus, early recognition of this entity could be important for appropriate disease management. Here we report the first Korean case, as well as the first case in an adolescent, of NK-cell enteropathy.","PeriodicalId":49936,"journal":{"name":"Korean Journal of Pathology","volume":"48 1","pages":"73-6"},"PeriodicalIF":0.0,"publicationDate":"2014-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4132/KoreanJPathol.2014.48.1.73","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32174566","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 17

P2X7 Receptor Expression in Coexistence of Papillary Thyroid Carcinoma with Hashimoto's Thyroiditis. P2X7受体在乳头状甲状腺癌与桥本甲状腺炎共存中的表达。

Korean Journal of Pathology Pub Date : 2014-02-01 Epub Date: 2014-02-25 DOI: 10.4132/KoreanJPathol.2014.48.1.30

Ji Hyun Kwon, Eun Sook Nam, Hyung Sik Shin, Seong Jin Cho, Hye Rim Park, Mi Jung Kwon

{"title":"P2X7 Receptor Expression in Coexistence of Papillary Thyroid Carcinoma with Hashimoto's Thyroiditis.","authors":"Ji Hyun Kwon, Eun Sook Nam, Hyung Sik Shin, Seong Jin Cho, Hye Rim Park, Mi Jung Kwon","doi":"10.4132/KoreanJPathol.2014.48.1.30","DOIUrl":"https://doi.org/10.4132/KoreanJPathol.2014.48.1.30","url":null,"abstract":"Background: This study was aimed at investigating the relation of P2X7 receptor (P2X7R) expression with the clinicopathological features of papillary thyroid carcinoma (PTC) coexisting with Hashimoto's thyroiditis (HT).Methods: We examined 170 patients (84, PTC with HT; 86, PTC without HT). P2X7R expression was examined by immunohistochemical methods. The staining intensity and patterns were evaluated and scored using a semi-quantitative method.Results: The PTC with HT group was more likely to contain women and had less extrathyroid extension, lymph node (LN) metastasis, lymphovascular invasion, and recurrence than the PTC without HT group. Patients positive for P2X7R had significantly higher frequencies of lymphovascular invasion, extrathyroid extension, LN metastasis, and absence of HT. As shown by multivariate analysis, the expression of P2X7R was significantly higher if HT was absent and extrathyroid extension was present. In the PTC with HT group, the expression of P2X7R was significantly higher in patients with tumor multifocality, lymphovascular invasion, and extrathyroid extension. In the PTC without HT group, the expression of P2X7R was significantly higher in women and those having tumor multifocality.Conclusions: Coexistence of PTC with HT is associated with good prognostic factors, and P2X7R expression in PTC was correlated with poor prognostic factors and the absence of HT.","PeriodicalId":49936,"journal":{"name":"Korean Journal of Pathology","volume":"48 1","pages":"30-5"},"PeriodicalIF":0.0,"publicationDate":"2014-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4132/KoreanJPathol.2014.48.1.30","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32174557","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 23

Primary myxoid leiomyoma of the liver. 原发性肝脏黏液样平滑肌瘤。

Korean Journal of Pathology Pub Date : 2014-02-01 Epub Date: 2014-02-25 DOI: 10.4132/KoreanJPathol.2014.48.1.54

Hee Seung Choi, Chang Won Jung, Soo Youn Cho, Sang Bum Kim, Sunhoo Park

引用次数: 13

Primary sigmoid adenocarcinoma metastasis to the breast in a 28-year-old female: a case study and a review of literature. 原发性乙状结肠腺癌转移至乳房一例28岁女性:个案研究及文献复习。

Korean Journal of Pathology Pub Date : 2014-02-01 Epub Date: 2014-02-25 DOI: 10.4132/KoreanJPathol.2014.48.1.58

Amna Ahmad, Kweku Baiden-Amissah, Adegoke Oyegade, Mohammed Absar, Kate Swainson, Sami Titi

{"title":"Primary sigmoid adenocarcinoma metastasis to the breast in a 28-year-old female: a case study and a review of literature.","authors":"Amna Ahmad, Kweku Baiden-Amissah, Adegoke Oyegade, Mohammed Absar, Kate Swainson, Sami Titi","doi":"10.4132/KoreanJPathol.2014.48.1.58","DOIUrl":"https://doi.org/10.4132/KoreanJPathol.2014.48.1.58","url":null,"abstract":"Metastasis to the breast from colorectal carcinoma is rare, only a few cases have been reported in the literature, and no cases have been reported in a young, 28-year-old patient. This report confirms the occurrence of the disease in a younger age group. The patient was referred to the Breast Clinic with a history of a gradually increasing lump in her right breast for two weeks' duration. On clinical examination, a 2-cm firm lump was noted in the upper inner quadrant of the right breast, which was clinically benign; however, histological examination of the breast core biopsy together with immunohistochemistry confirmed metastatic colorectal adenocarcinoma. The primary colorectal carcinoma was later confirmed to be a stage pT4N2M1 tumor, and the Duke stage was C1. Histology with immunohistochemistry is very important in the diagnosis of cases of this nature, but the clinical correlation should be taken into consideration at multidisciplinary team meetings to decide the final management of the patient. ","PeriodicalId":49936,"journal":{"name":"Korean Journal of Pathology","volume":"48 1","pages":"58-61"},"PeriodicalIF":0.0,"publicationDate":"2014-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4132/KoreanJPathol.2014.48.1.58","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32174562","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 14

Adenocarcinoma arising in a colonic duplication cyst: a case report and review of the literature. 结肠重复囊肿引起的腺癌:1例报告及文献复习。

Korean Journal of Pathology Pub Date : 2014-02-01 Epub Date: 2014-02-25 DOI: 10.4132/KoreanJPathol.2014.48.1.62

Myunghee Kang, Jungsuk An, Dong Hae Chung, Hyun Yee Cho

引用次数: 7

Crush cytology of microcystic meningioma with extensive sclerosis. 微囊性脑膜瘤伴广泛硬化的粉碎细胞学分析。

Korean Journal of Pathology Pub Date : 2014-02-01 Epub Date: 2014-02-25 DOI: 10.4132/KoreanJPathol.2014.48.1.77

Jae Yeon Seok, Na Rae Kim, Hyun Yee Cho, Dong Hae Chung, Gi-Taek Yee, Eung Yeop Kim

引用次数: 7

Guideline Recommendations for Testing of ALK Gene Rearrangement in Lung Cancer: A Proposal of the Korean Cardiopulmonary Pathology Study Group. 肺癌中ALK基因重排检测的指南建议:韩国心肺病理研究组的建议。

Korean Journal of Pathology Pub Date : 2014-02-01 Epub Date: 2014-02-25 DOI: 10.4132/KoreanJPathol.2014.48.1.1

Hyojin Kim, Hyo Sup Shim, Lucia Kim, Tae-Jung Kim, Kun Young Kwon, Geon Kook Lee, Jin-Haeng Chung

引用次数: 23

Large cell calcifying sertoli cell tumor of the testis: a case study and review of the literature. 睾丸大细胞钙化支持细胞瘤:个案研究及文献复习。

Korean Journal of Pathology Pub Date : 2014-02-01 Epub Date: 2014-02-25 DOI: 10.4132/KoreanJPathol.2014.48.1.50

Dae Hyun Song, Seong Muk Jeong, Jong Tak Park, Gak Won Yun, Byoung Kwon Kim, Jong Sil Lee

{"title":"Large cell calcifying sertoli cell tumor of the testis: a case study and review of the literature.","authors":"Dae Hyun Song, Seong Muk Jeong, Jong Tak Park, Gak Won Yun, Byoung Kwon Kim, Jong Sil Lee","doi":"10.4132/KoreanJPathol.2014.48.1.50","DOIUrl":"https://doi.org/10.4132/KoreanJPathol.2014.48.1.50","url":null,"abstract":"A 24-year-old man was admitted due to an incidentally detected mass in his left testis, which showed radiopaque calcification on plain X-ray film. Left orchiectomy was performed, and the resected testis contained a well-demarcated, hard mass measuring 1.1 cm. Histological analysis revealed that the tumor was composed of neoplastic cells, fibrotic stroma, and laminated or irregularly shaped calcific bodies. The individual cells had abundant eosinophilic or clear cytoplasm with round nuclei, each of which contained one or two conspicuous nucleoli. They were arranged in cords, trabeculae, clusters, and diffuse sheets. There were several foci of intra-tubular growth patterns, with thickening of the basal lamina. Immunohistochemically, the neoplastic cells were positive for S-100 protein and vimentin, focally positive for inhibin alpha, and negative for cytokeratin, CD10, and Melan-A. In addition to reporting this rare case, we also review the relevant literature regarding large cell calcifying Sertoli cell tumors. ","PeriodicalId":49936,"journal":{"name":"Korean Journal of Pathology","volume":"48 1","pages":"50-3"},"PeriodicalIF":0.0,"publicationDate":"2014-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4132/KoreanJPathol.2014.48.1.50","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32174560","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 8

Usual interstitial pneumonia with lung cancer: clinicopathological analysis of 43 cases. 常见间质性肺炎合并肺癌43例临床病理分析。

Korean Journal of Pathology Pub Date : 2014-02-01 Epub Date: 2014-02-25 DOI: 10.4132/KoreanJPathol.2014.48.1.10

Dae Hyun Song, In Ho Choi, Sang Yun Ha, Kang Min Han, Jae Jun Lee, Min Eui Hong, Kyeongman Jeon, Man Pyo Chung, Jhingook Kim, Joungho Han

{"title":"Usual interstitial pneumonia with lung cancer: clinicopathological analysis of 43 cases.","authors":"Dae Hyun Song, In Ho Choi, Sang Yun Ha, Kang Min Han, Jae Jun Lee, Min Eui Hong, Kyeongman Jeon, Man Pyo Chung, Jhingook Kim, Joungho Han","doi":"10.4132/KoreanJPathol.2014.48.1.10","DOIUrl":"https://doi.org/10.4132/KoreanJPathol.2014.48.1.10","url":null,"abstract":"Background: Previous studies have suggested an association between usual interstitial pneumonia (UIP) and lung cancer (Ca). However, clinical and histological information is not enough to determine such an association, due to the low incidence and short survival time of patients with both conditions.Methods: We retrospectively reviewed the clinical and histological records of Ca patients with UIP between January 1999 and August 2013 at the Samsung Medical Center, Seoul, Korea. We found 43 patients who had Ca with UIP (UIP-Ca). Previously reported data of eighty-four patients with UIP-only were included as a comparison group.Results: Smoking is related to poor prognosis in patients with UIP-Ca, and the number of patients with a high smoking index of more than 30 pack-years significantly increased in UIP-Ca patients compared with UIP-only patients. There is no significant prognostic differentiation between UIP-Ca patients and UIP-only patients. Microscopically, UIP-Ca patients showed characteristically heterogeneous histological patterns and degrees of differentiation. There were many foci of squamous metaplasia or dysplasia at the peripheral area of squamous cell carcinomas.Conclusions: We report 43 cases of UIP-Ca. Our results suggest that smoking is related to cancer occurrence in UIP patients and poor prognosis in UIP-Ca patients.","PeriodicalId":49936,"journal":{"name":"Korean Journal of Pathology","volume":"48 1","pages":"10-6"},"PeriodicalIF":0.0,"publicationDate":"2014-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4132/KoreanJPathol.2014.48.1.10","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32174102","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 18

Peritoneal and nodal gliomatosis with endometriosis, accompanied with ovarian immature teratoma: a case study and literature review. 腹膜和淋巴结胶质瘤病合并子宫内膜异位症，并伴有卵巢未成熟畸胎瘤:一个病例研究和文献复习。

Korean Journal of Pathology Pub Date : 2013-12-01 Epub Date: 2013-12-24 DOI: 10.4132/KoreanJPathol.2013.47.6.587

Na Rae Kim, Soyi Lim, Juhyeon Jeong, Hyun Yee Cho

{"title":"Peritoneal and nodal gliomatosis with endometriosis, accompanied with ovarian immature teratoma: a case study and literature review.","authors":"Na Rae Kim, Soyi Lim, Juhyeon Jeong, Hyun Yee Cho","doi":"10.4132/KoreanJPathol.2013.47.6.587","DOIUrl":"https://doi.org/10.4132/KoreanJPathol.2013.47.6.587","url":null,"abstract":"Gliomatosis peritonei (GP) indicates the peritoneal implantation of mature neuroglial tissue and is usually accompanied by ovarian mature or immature teratoma. Here, we report a case of ovarian immature teratoma associated with gliomatosis involving the peritoneum, lymph nodes and Douglas' pouch, where gliomatosis coexisted with endometriosis. As far as we know, only seven cases of GP have been reported as coexisting with endometriosis. Eight cases with mature glial tissue in the lymph nodes, i.e., nodal gliomatosis, have been published either in association with GP or in its absence. Metaplasia of pluripotent coelomic stem cells has been suggested to be responsible for the pathogenesis of endometriosis and GP rather than implantation metastases of ovarian teratomatous tumor with varying maturation. This theory is also applied to GP independently of ovarian teratomatous tumors. To the best of our knowledge, nodal gliomatosis coexisting with GP and also involving endometriosis has not yet been reported. ","PeriodicalId":49936,"journal":{"name":"Korean Journal of Pathology","volume":"47 6","pages":"587-91"},"PeriodicalIF":0.0,"publicationDate":"2013-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4132/KoreanJPathol.2013.47.6.587","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32028640","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 13