{"title":"[Perianal tuberculosis].","authors":"Asdis Kristjansdottir, Agnar Bjarnason, Gigja Erlingsdottir, Pall Helgi Moller","doi":"10.17992/lbl.2026.03.883","DOIUrl":"10.17992/lbl.2026.03.883","url":null,"abstract":"<p><p>Perianal tuberculosis is a rare manifestation of tuberculosis. This report describes a healthy 41-year-old man diagnosed with a perianal abscess that required examination and surgical drainage under general anesthesia. The wound healed poorly over the following months, prompting repeat cultures and tissue sampling. Histological diagnosis revealed necrotizing granulomatous inflammation and acid-fast bacilli, indicating mycobacterial infection. Further investigation revealed pulmonary tuberculosis. The patient received a six-month course of anti-tuberculosis medications and recovered fully. The perianal wound healed well following treatment. Tuberculosis is an important differential diagnosis in individuals with a wound or a lesion near the anus or elsewhere that heals slowly or recurs.</p>","PeriodicalId":49924,"journal":{"name":"Laeknabladid","volume":"112 3","pages":"120-123"},"PeriodicalIF":0.4,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147285828","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
LaeknabladidPub Date : 2026-03-01DOI: 10.17992/lbl.2026.03.882
Kristin Fjola Jonsdottir, Hildur Jonsdottir, Einar S Bjornsson
{"title":"[Alcohol related hospitalizations in Landspitali University Hospital have increased significantly in recent years].","authors":"Kristin Fjola Jonsdottir, Hildur Jonsdottir, Einar S Bjornsson","doi":"10.17992/lbl.2026.03.882","DOIUrl":"10.17992/lbl.2026.03.882","url":null,"abstract":"<p><strong>Introduction: </strong>The harmful effects of alcohol are well known but a variable proportion of hospital admissions are due to alcohol related problems. The aim of the current study was to examine the number of alcohol-related admissions to Landspitali University Hospital 2005-2022 and to investigate whether there has been an increase during the period.</p><p><strong>Methods: </strong>A search was undertaken for alcohol related ICD-10 diagnostic codes at the Landspítali University Hospital and information was collected on all those who had received one or more of these diagnoses upon discharge from 2005 to 2022. Relevant clinical data was obtained.</p><p><strong>Results: </strong>A total of 2925 alcohol-related admissions were found during the study period, 1779 patients were admitted, 1168 men (66%) and 611 women (34%), with a median age of 54 years. Alcohol-related admissions increased from 34 per 100,000 population in 2005 to 64 per 100,000 in 2022. At the beginning of the study period, the proportion of alcohol-related admissions of all admissions to Landspítali was 0.32% whereas at the end of the period, the proportion had increased to 0.95%. The median length of stay was 6 days. The dominating diagnoses were related to mental and behavioural disorders (n=1878), alcohol-related liver disease (n=923), alcohol-related pancreatitis (n=457), and diseases of the nervous system (n=210), of whom 144 had Wernicke's disease.</p><p><strong>Conclusions: </strong>Alcohol-related hospitalizations increased by 88% between 2005 and 2022. The most common diagnoses were mental and behavioral disorders and liver and pancreatic diseases. This has led to a significant cost increase for the healthcare system and society as a whole.</p>","PeriodicalId":49924,"journal":{"name":"Laeknabladid","volume":"112 3","pages":"110-118"},"PeriodicalIF":0.4,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147285755","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
LaeknabladidPub Date : 2026-01-01DOI: 10.17992/lbl.2026.01.874
Hakon Orn Grimsson, Kristin Huld Haraldsdottir
{"title":"[Complications of salmonella poisoning - case report].","authors":"Hakon Orn Grimsson, Kristin Huld Haraldsdottir","doi":"10.17992/lbl.2026.01.874","DOIUrl":"10.17992/lbl.2026.01.874","url":null,"abstract":"<p><p>A rare cause of cholecystitis is bacterial infection caused by Salmonella. Complications can be very severe, but are rare, and include fistula formation, intestinal obstruction caused by gallstones or inflammation, and even necrosis and rupture or perforation of adjacent tissue or organs.</p>","PeriodicalId":49924,"journal":{"name":"Laeknabladid","volume":"112 1","pages":"24-27"},"PeriodicalIF":0.6,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145776260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
LaeknabladidPub Date : 2025-12-01DOI: 10.17992/lbl.2025.12.865
Johannes Kari Kristinsson Kari Kristinsson
{"title":"[Acanthamoeba Keratitis: Rare but Not to Be Overlooked].","authors":"Johannes Kari Kristinsson Kari Kristinsson","doi":"10.17992/lbl.2025.12.865","DOIUrl":"https://doi.org/10.17992/lbl.2025.12.865","url":null,"abstract":"","PeriodicalId":49924,"journal":{"name":"Laeknabladid","volume":"111 12","pages":"523"},"PeriodicalIF":0.6,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145642349","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
LaeknabladidPub Date : 2025-12-01DOI: 10.17992/lbl.2025.12.867
Sigurros Jonsdottir, Ingibjorg Hilmarsdottir Hilmarsdottir, Daniel Alexandersso, Gunnar Mar Zoega
{"title":"[Acanthamoeba keratitis in Iceland from 1996-2021].","authors":"Sigurros Jonsdottir, Ingibjorg Hilmarsdottir Hilmarsdottir, Daniel Alexandersso, Gunnar Mar Zoega","doi":"10.17992/lbl.2025.12.867","DOIUrl":"https://doi.org/10.17992/lbl.2025.12.867","url":null,"abstract":"<p><strong>Introduction: </strong>Acanthamoeba keratitis is a rare but serious eye infection primarily associated with contact lens use. Its diagnosis is often delayed due to treatment challenges, frequent co-infections, and the amoeba's high resistance, leading to significant visual impairment. This study assessed the incidence of Acanthamoeba keratitis in Iceland over 25 years, identified risk factors, diagnostic difficulties, and explored potential improvements.</p><p><strong>Materials and methods: </strong>A retrospective descriptive study including all individuals diagnosed with amoebic corneal infection in Iceland from 1996-2021. Data were retrieved from culture results in Landspitali's Department of Microbiology and patient records. Selected cases were presented in detail.</p><p><strong>Results: </strong>Nine cases were identified, with an incidence of 0.11 per 100,000 individuals over the period. All cases had a history of contact lens use, all but one experienced severe pain, and six were misdiagnosed with herpes viral infection. All patients were treated with diamidines and biguanides, but five received steroid treatment before amoeba diagnosis. Two patients required surgery. The total duration of treatment ranged from 5-24 months, with follow-up periods ranging from 4-110 months. Visual acuity at the last examination was 0-1,25 on the Snellen scale.</p><p><strong>Discussion: </strong>Awareness of environmental amoebas and early diagnosis are key to preventing Acanthamoeba keratitis. Prevention efforts should focus on contact lens users, with targeted education. Diagnostic and treatment guidelines are lacking, and physicians should always consider Acanthamoeba in keratitis cases, particularly in contact lens wearers.</p>","PeriodicalId":49924,"journal":{"name":"Laeknabladid","volume":"111 12","pages":"526-531"},"PeriodicalIF":0.6,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145642360","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
LaeknabladidPub Date : 2025-12-01DOI: 10.17992/lbl.2025.12.869
Olafur Palsson, Dora Ludviksdottir
{"title":"[Christmas tree - Case of the month].","authors":"Olafur Palsson, Dora Ludviksdottir","doi":"10.17992/lbl.2025.12.869","DOIUrl":"10.17992/lbl.2025.12.869","url":null,"abstract":"<p><p>This case report describes a patient presenting with anterior chest pain, cough and polyarthritis with significant systemic inflammatory reaction. On FDG-PET scanning there was significant uptake in the the costochondral cartilage, trachea and joints leading to a diagnosis of relapsing polychondritis.</p>","PeriodicalId":49924,"journal":{"name":"Laeknabladid","volume":"111 12","pages":"538-539"},"PeriodicalIF":0.6,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145642292","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
LaeknabladidPub Date : 2025-12-01DOI: 10.17992/lbl.2025.12.866
Solrun Melkorka Maggadottir
{"title":"[The fine art of immune balance: Reflections on the 2025 Nobel prize in medicine.]","authors":"Solrun Melkorka Maggadottir","doi":"10.17992/lbl.2025.12.866","DOIUrl":"https://doi.org/10.17992/lbl.2025.12.866","url":null,"abstract":"","PeriodicalId":49924,"journal":{"name":"Laeknabladid","volume":"111 12","pages":"525"},"PeriodicalIF":0.6,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145641855","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
LaeknabladidPub Date : 2025-12-01DOI: 10.17992/lbl.2025.12.868
OlafurSveinsson Arni Sveinsson, Jordan Cunningham, Brynhildur Thors
{"title":"[New recommedations in the treatment of restless legs syndrome - dopaminergic drugs on the way out].","authors":"OlafurSveinsson Arni Sveinsson, Jordan Cunningham, Brynhildur Thors","doi":"10.17992/lbl.2025.12.868","DOIUrl":"https://doi.org/10.17992/lbl.2025.12.868","url":null,"abstract":"<p><p>Restless legs syndrome (RLS) is a common sleep-related movement disorder marked by an urge to move one or both legs (sometimes the arms), especially during periods of immobility. This urge is often accompanied by uncomfortable sensations (dysesthesias) and is typically worse in the evening or at night. Movement provides temporary relief. RLS can significantly disrupt sleep and is frequently associated with periodic limb movement disorder (PLMD), characterized by involuntary muscle contractions during sleep, further impairing sleep quality. The most common causes of RLS are heredity and iron deficiency. New treatment guidelines have introduced major changes. First, dopamine agonists, previously first-line treatment in the 2012 guidelines, are no longer recommended for routine use due to the risk of symptom augmentation. If used, then at low doses for short durations only. Second, iron plays a critical role in the condition's pathophysiology and treatment. Iron therapy, either oral or intravenous, is advised when ferritin levels are below 75 ng/mL, to reach above 100 ng/mL. These recommendations differ from standard guidelines for the general population. Third, if iron levels are sufficient, gabapentin or pregabalin are now recommended as first-line treatment. This article reviews the symptoms, causes, and updated treatment guidelines for RLS.</p>","PeriodicalId":49924,"journal":{"name":"Laeknabladid","volume":"111 12","pages":"532-537"},"PeriodicalIF":0.6,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145642307","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
LaeknabladidPub Date : 2025-11-01DOI: 10.17992/lbl.2025.11.860
Oddur Ingimarsson
{"title":"[Domestic Violence: A Serious, Widespread Health Problem].","authors":"Oddur Ingimarsson","doi":"10.17992/lbl.2025.11.860","DOIUrl":"https://doi.org/10.17992/lbl.2025.11.860","url":null,"abstract":"","PeriodicalId":49924,"journal":{"name":"Laeknabladid","volume":"111 11","pages":"463"},"PeriodicalIF":0.6,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145460207","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}