[Operations for neuroendocrine tumors in upper gastrointestinal tract in Landspitali University Hospital-Reasearch].

Abstract

Introduction: Neuroendocrine tumors are rare tumors, originating from the neuroendocrine system. They originate most commonly in the lungs and gastrointestinal organs. These tumors differ according to their origin and maturity. Neuroendocrine tumors can be hormonally active or inactive.

Method: This is a retrospective study of patients that had surgery for a neuroendocrine tumor in the upper gastrointestinal organs, in the period 2010-2020. Tumor origin was registered, as well as operations and factors related to the operations, complications, and survival rate. Patients who underwent surgery for a primary tumor in the upper gastrointestinal tract, or liver metastasis were included. Data was gathered from medical charts from Landspitali University Hospital, and analyzed with descriptive and survival statistics with the help of the softwares Microsoft Excel and GraphPad Prism. Appropriate permits were gathered.

Results: In total, 31 patients, was operated for neuroendocrine tumors in the upper gastrointestinal tract but tumor resection was only done on 29 patients. Those 29 patients made the study sample. 34% of the patients had complications that required intervention or intensive care treatment. No patient died within 30 days of the operation. Total survival of the patients was 88% and disease specific survival was 95%.

Conclusion: Few patients are operated on for a neuroendocrine tumor in the upper gastrointestinal tract each year. The surgeries were successful, and survival is comparable to other studies.