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What Is the Role of Circulating Tumor DNA in Patients With HPV-Related Oropharyngeal Cancer? 循环肿瘤DNA在hpv相关口咽癌患者中的作用？
IF 2 3区 医学
Laryngoscope Pub Date : 2025-09-04 DOI: 10.1002/lary.70088
Chelsea A Gelboin-Burkhart, Kevin J Contrera, Matthew E Spector, Jessica H Maxwell
{"title":"What Is the Role of Circulating Tumor DNA in Patients With HPV-Related Oropharyngeal Cancer?","authors":"Chelsea A Gelboin-Burkhart, Kevin J Contrera, Matthew E Spector, Jessica H Maxwell","doi":"10.1002/lary.70088","DOIUrl":"https://doi.org/10.1002/lary.70088","url":null,"abstract":"","PeriodicalId":49921,"journal":{"name":"Laryngoscope","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145001830","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Thyroid Cartilage Fracture Following Endotracheal Intubation. 气管插管后甲状软骨骨折。
IF 2 3区 医学
Laryngoscope Pub Date : 2025-09-04 DOI: 10.1002/lary.70093
T Khalid, N Lloyd, M Shand, W Montagne, R Wang
{"title":"Thyroid Cartilage Fracture Following Endotracheal Intubation.","authors":"T Khalid, N Lloyd, M Shand, W Montagne, R Wang","doi":"10.1002/lary.70093","DOIUrl":"https://doi.org/10.1002/lary.70093","url":null,"abstract":"","PeriodicalId":49921,"journal":{"name":"Laryngoscope","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144994089","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prevalence of Long-Term Dysphagia in Head and Neck Cancer Survivors Not Receiving Dysphagia Treatment. 未接受吞咽困难治疗的头颈癌幸存者长期吞咽困难的患病率
IF 2 3区 医学
Laryngoscope Pub Date : 2025-09-03 DOI: 10.1002/lary.70085
Arushi Gulati, Nina Patel, Joseph Kidane, Claire E Perrin, Jason W Chan, Tyler W Crosby, VyVy N Young, Clark A Rosen, Sue S Yom, Patrick K Ha, Sarah L Schneider, Yue Ma
{"title":"Prevalence of Long-Term Dysphagia in Head and Neck Cancer Survivors Not Receiving Dysphagia Treatment.","authors":"Arushi Gulati, Nina Patel, Joseph Kidane, Claire E Perrin, Jason W Chan, Tyler W Crosby, VyVy N Young, Clark A Rosen, Sue S Yom, Patrick K Ha, Sarah L Schneider, Yue Ma","doi":"10.1002/lary.70085","DOIUrl":"10.1002/lary.70085","url":null,"abstract":"<p><strong>Objective: </strong>In head and neck cancer (HNC) survivors not actively receiving dysphagia care, long-term dysphagia prevalence, dysphagia-related complications, and quality of life outcomes remain poorly understood. Understanding these outcomes is critical for creating effective HNC survivorship programs.</p><p><strong>Methods: </strong>HNC survivors who completed cancer treatment > 2 years prior who had not undergone a swallow evaluation or therapy for > 1 year completed the MD Anderson Dysphagia Inventory (MDADI) and reported dysphagia-related complications.</p><p><strong>Results: </strong>Of 722 invited participants who met inclusion criteria, 143 responded at a median of 5.9 years (IQR: 2.5-10.2 years) post-treatment, including 65 at 2-5 years, 42 at 5-10 years, and 36 at > 10 years. Median time since last speech-language pathologist visit was 2.8 years (IQR 2.1-4.9 years), and 27% had not received any swallow therapy since cancer treatment completion. The most common tumor subsite was oropharynx (n = 103), and most underwent definitive (n = 72) or adjuvant (n = 60) (chemo)radiation. The overall median MDADI score was 80 points (IQR: 62.1-91.6) and 49.6% (n = 71) had moderate to severe dysphagia (MDADI < 80). The most common complications within the 6 months prior to patient contact were unintentional weight loss (7.7%), current gastrostomy tube dependence (4.9%), aspiration pneumonia (1.4%), and dehydration requiring intravenous fluids (1.4%). An MDADI score ≤ 80 was associated with 7.7 times higher odds of dysphagia-related adverse events (95% CI 2.1-28.2, p = 0.002).</p><p><strong>Conclusions: </strong>Long-term dysphagia is prevalent among HNC survivors not actively receiving dysphagia care, highlighting the need for ongoing swallow function surveillance and proactive dysphagia management strategies tailored to this population.</p><p><strong>Level of evidence: 3: </strong></p>","PeriodicalId":49921,"journal":{"name":"Laryngoscope","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144976578","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
In Response to Inconsistent Associations of Modified Frailty Index-5 With Adverse Head and Neck Reconstruction Outcomes. 修改后的虚弱指数-5与头颈部重建结果的不一致关联
IF 2 3区 医学
Laryngoscope Pub Date : 2025-09-03 DOI: 10.1002/lary.70096
Doruk Orgun, Samuel O Poore
{"title":"In Response to Inconsistent Associations of Modified Frailty Index-5 With Adverse Head and Neck Reconstruction Outcomes.","authors":"Doruk Orgun, Samuel O Poore","doi":"10.1002/lary.70096","DOIUrl":"10.1002/lary.70096","url":null,"abstract":"","PeriodicalId":49921,"journal":{"name":"Laryngoscope","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144976533","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Does Early Laser Treatment of Capillary Malformations Lead to More Favorable Outcomes? 早期激光治疗毛细血管畸形会带来更好的结果吗？
IF 2 3区 医学
Laryngoscope Pub Date : 2025-09-03 DOI: 10.1002/lary.70099
Larkin Harris, Reema Padia
{"title":"Does Early Laser Treatment of Capillary Malformations Lead to More Favorable Outcomes?","authors":"Larkin Harris, Reema Padia","doi":"10.1002/lary.70099","DOIUrl":"10.1002/lary.70099","url":null,"abstract":"","PeriodicalId":49921,"journal":{"name":"Laryngoscope","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144976406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
In Reference to Effect of Auditory Input on Sensory Organization and Fall Risk in Young Adults With Hearing Aids. 听力输入对青少年助听器感觉组织及跌倒风险的影响。
IF 2 3区 医学
Laryngoscope Pub Date : 2025-09-03 DOI: 10.1002/lary.70097
Preethi Ravindranath, Sharad Ashish
{"title":"In Reference to Effect of Auditory Input on Sensory Organization and Fall Risk in Young Adults With Hearing Aids.","authors":"Preethi Ravindranath, Sharad Ashish","doi":"10.1002/lary.70097","DOIUrl":"https://doi.org/10.1002/lary.70097","url":null,"abstract":"","PeriodicalId":49921,"journal":{"name":"Laryngoscope","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144976367","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
In Reference to Frontal Sinus Patency After Sinus Surgery Using Triamcinolone-Impregnated Plant-Based Sinus Spacers. 应用曲安奈德浸透植物性鼻窦垫片治疗鼻窦手术后额窦通畅。
IF 2 3区 医学
Laryngoscope Pub Date : 2025-09-03 DOI: 10.1002/lary.70111
Smile Kajal
{"title":"In Reference to Frontal Sinus Patency After Sinus Surgery Using Triamcinolone-Impregnated Plant-Based Sinus Spacers.","authors":"Smile Kajal","doi":"10.1002/lary.70111","DOIUrl":"10.1002/lary.70111","url":null,"abstract":"","PeriodicalId":49921,"journal":{"name":"Laryngoscope","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144976481","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
In Reference to Inconsistent Associations of Modified Frailty Index-5 With Adverse Head and Neck Reconstruction Outcomes. 修改后的虚弱指数-5与头颈部重建结果的不一致关联
IF 2 3区 医学
Laryngoscope Pub Date : 2025-09-03 DOI: 10.1002/lary.70098
Akshay Warrier, Jeel Patel, Christian A Bowers, Richard Gurgel
{"title":"In Reference to Inconsistent Associations of Modified Frailty Index-5 With Adverse Head and Neck Reconstruction Outcomes.","authors":"Akshay Warrier, Jeel Patel, Christian A Bowers, Richard Gurgel","doi":"10.1002/lary.70098","DOIUrl":"https://doi.org/10.1002/lary.70098","url":null,"abstract":"","PeriodicalId":49921,"journal":{"name":"Laryngoscope","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144976505","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
In Response to Effect of Auditory Input on Sensory Organization and Fall Risk in Young Adults With Hearing Aids. 听力输入对青少年助听器感觉组织及跌倒风险的影响。
IF 2 3区 医学
Laryngoscope Pub Date : 2025-09-03 DOI: 10.1002/lary.70101
Emre Orhan, Volkan Tutar, Bülent Gündüz, Recep Karamert, Mehmet Birol Uğur, Hakan Tutar
{"title":"In Response to Effect of Auditory Input on Sensory Organization and Fall Risk in Young Adults With Hearing Aids.","authors":"Emre Orhan, Volkan Tutar, Bülent Gündüz, Recep Karamert, Mehmet Birol Uğur, Hakan Tutar","doi":"10.1002/lary.70101","DOIUrl":"https://doi.org/10.1002/lary.70101","url":null,"abstract":"","PeriodicalId":49921,"journal":{"name":"Laryngoscope","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144976528","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sterile Nasal Septal Abscess in Ulcerative Colitis With Crypt Abscess-Like Neutrophilic Infiltration. 溃疡性结肠炎伴隐窝脓肿样中性粒细胞浸润的无菌鼻中隔脓肿。
IF 2 3区 医学
Laryngoscope Pub Date : 2025-09-03 DOI: 10.1002/lary.70106
Masakazu Murayama, Yoshihito Tanaka, Tomoyuki Yokose, Toshikazu Shimane
{"title":"Sterile Nasal Septal Abscess in Ulcerative Colitis With Crypt Abscess-Like Neutrophilic Infiltration.","authors":"Masakazu Murayama, Yoshihito Tanaka, Tomoyuki Yokose, Toshikazu Shimane","doi":"10.1002/lary.70106","DOIUrl":"https://doi.org/10.1002/lary.70106","url":null,"abstract":"<p><p>We report a rare case of a sterile nasal septal abscess (NSA) occurring as an extraintestinal manifestation of ulcerative colitis (UC), accompanied by a novel histopathologic finding. A 40-year-old woman with relapsed UC presented with nasal swelling, purulent discharge, hematochezia, and skin lesions. Computed tomography revealed an anterior NSA, and emergent endoscopic drainage was performed. Despite broad-spectrum antibiotics, her condition worsened, and corticosteroids were initiated. Histopathologic analysis of the nasal mucosa demonstrated crypt abscess-like neutrophilic infiltration within glandular structures, resembling colonic crypt abscesses in active UC. Cultures were negative, and her condition improved with immunosuppressive therapy. To our knowledge, this is the first reported case of a sterile NSA with crypt abscess-like structures in the nasal mucosa, expanding the histopathologic spectrum of sinonasal manifestations in UC. Early recognition and prompt immunosuppressive therapy are essential to avoid complications such as saddle nose deformity.</p>","PeriodicalId":49921,"journal":{"name":"Laryngoscope","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144976068","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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