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Evaluating the Effect of Various Pure Tone Averages on Cochlear Implant Candidacy Screening. 评估各种纯音平均值对人工耳蜗候选筛选的影响。
IF 2.2 3区 医学
Laryngoscope Pub Date : 2025-01-21 DOI: 10.1002/lary.32018
Rachel C Greiner, Arun M Raghavan, Noga Lipschitz, Gavriel D Kohlberg
{"title":"Evaluating the Effect of Various Pure Tone Averages on Cochlear Implant Candidacy Screening.","authors":"Rachel C Greiner, Arun M Raghavan, Noga Lipschitz, Gavriel D Kohlberg","doi":"10.1002/lary.32018","DOIUrl":"https://doi.org/10.1002/lary.32018","url":null,"abstract":"<p><strong>Objective: </strong>To provide evidence to use an extended frequency pure tone average to screen for cochlear implant evaluation candidates as recommended by the American Cochlear Implant Alliance. Additionally, to determine whether traditional low frequency, high or low frequency, high frequency, or extended frequency pure tone average most accurately predicts cochlear implant candidates based on speech perception scores from aided AzBio sentence testing or aided consonant-nucleus-consonant (CNC) testing.</p><p><strong>Method: </strong>Adults from a tertiary care center who completed aided sentence testing during cochlear implant evaluation between 2014 and 2024 were assessed. Pure tone averages at low, high, low or high, and extended frequency ranges were evaluated with individual ear's aided AzBio or aided CNC scores as an outcome. Sensitivity, specificity, negative predictive value, and positive predictive value were assessed and compared using a paired study design.</p><p><strong>Results: </strong>There were 675 observations from 363 patients with AzBio as an outcome variable and 665 observations from 364 patients with CNC scores as an outcome variable. High or low frequency achieved the highest sensitivity at 96.3% AzBio as an outcome and 95.6% with CNC as an outcome, which was significantly better than low frequency (p < 0.001). Low frequency achieved the best specificity at 63.6% with AzBio as an outcome 76.9% with CNC as an outcome.</p><p><strong>Conclusion: </strong>Extended frequency pure tones resulted in greater sensitivity in predicting CI candidates compared with the traditionally used low frequency pure tone average. Screening with wider frequency values will lead to a greater number of patients being identified for a cochlear implant evaluation.</p><p><strong>Level of evidence: </strong>Level 3 Laryngoscope, 2025.</p>","PeriodicalId":49921,"journal":{"name":"Laryngoscope","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143014905","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Comparison of Therapy Adherence for Vocal Fold Atrophy and Chronic Cough. 声带萎缩与慢性咳嗽治疗依从性的比较。
IF 2.2 3区 医学
Laryngoscope Pub Date : 2025-01-19 DOI: 10.1002/lary.31971
Ari D Schuman, Jane B Buell, Varsha Varghese, Madeline E Brungardt, Sarah L Blumhardt, Julina Ongkasuwan, Adam R Szymanowski
{"title":"A Comparison of Therapy Adherence for Vocal Fold Atrophy and Chronic Cough.","authors":"Ari D Schuman, Jane B Buell, Varsha Varghese, Madeline E Brungardt, Sarah L Blumhardt, Julina Ongkasuwan, Adam R Szymanowski","doi":"10.1002/lary.31971","DOIUrl":"https://doi.org/10.1002/lary.31971","url":null,"abstract":"<p><strong>Introduction: </strong>Therapy is a common treatment for dysphonia attributable to vocal fold atrophy and chronic cough with the goal of decreasing procedural intervention. We compared the rates of therapy adherence and the factors associated with therapy adherence across groups.</p><p><strong>Methods: </strong>Retrospective chart review at a single institution since 2019. Groups were compared with chi-square and relative risk.</p><p><strong>Results: </strong>Across both diagnoses, 263 patients were identified; 131 (49.8%) with vocal fold atrophy and 132 (50.2%) with chronic cough. 173 patients (66%) were referred to speech therapy (81/131 atrophy, 61.8%; 91/132 cough, 69.7%; p = 0.207). Patients were evaluated in a multidisciplinary setting 30.1% of the time. Among those referred to therapy, patients who underwent their initial evaluation the same day within a multidisciplinary clinic were more likely to complete their course (30.7% vs 10.7%, p = 0.001). This association held on multivariable analysis (relative risk [RR] 2.39, 95% confidence interval 1.13-5.07, p = 0.02). Patients with atrophy and cough had similar therapy completion rates (22.2% vs 11.9%, p = 0.07). Male patients were more likely to complete therapy on multivariable analysis (RR 2.35, 1.16-4.47, p = 0.017). Patients who completed a procedure prior to therapy were not more likely to complete their course (p = 0.52).</p><p><strong>Conclusions: </strong>Multidisciplinary clinic with a speech pathologist and laryngologist is associated with an increased rate of therapy adherence in both vocal fold atrophy and chronic cough, regardless of diagnosis. Pre-therapy procedural interventions were not associated with increased therapy adherence.</p><p><strong>Level of evidence: </strong>3 Laryngoscope, 2025.</p>","PeriodicalId":49921,"journal":{"name":"Laryngoscope","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-01-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143015189","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Simple and Innovative Simulator Model for Sialendoscopy Basket Stone Retrieval Training. 一种简单创新的鼻内窥镜篮石回收训练模拟器模型。
IF 2.2 3区 医学
Laryngoscope Pub Date : 2025-01-18 DOI: 10.1002/lary.32017
Emad Ahmed Magdy, Samir Ali Elborolosy, Ahmed M Elbana, Mohamed F Fathalla
{"title":"A Simple and Innovative Simulator Model for Sialendoscopy Basket Stone Retrieval Training.","authors":"Emad Ahmed Magdy, Samir Ali Elborolosy, Ahmed M Elbana, Mohamed F Fathalla","doi":"10.1002/lary.32017","DOIUrl":"https://doi.org/10.1002/lary.32017","url":null,"abstract":"<p><p>We present a simple and innovative sialendoscopy basket stone retrieval (BSR) simulator model composed mainly of a 1.0-mL insulin syringe with detachable needle whose lumen mimics a dilated salivary duct. Dried Guava seeds are used to imitate small-sized floating sialoliths. The BSR simulator is evaluated by sialendoscopy trainees to ensure its realism and efficiency. Laryngoscope, 2025.</p>","PeriodicalId":49921,"journal":{"name":"Laryngoscope","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-01-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143014734","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Airway Management of Hypokalaemic Paralysis with Trismus and Bulbar Palsy Due To Conn's Syndrome. 康氏综合征所致低钾血症性麻痹伴锁骨及球性麻痹的气道管理。
IF 2.2 3区 医学
Laryngoscope Pub Date : 2025-01-16 DOI: 10.1002/lary.31976
Cristian Aragón-Benedí, Ana Pascual-Bellosta, Sonia Ortega-Lucea, Javier Martinez-Ubieto
{"title":"Airway Management of Hypokalaemic Paralysis with Trismus and Bulbar Palsy Due To Conn's Syndrome.","authors":"Cristian Aragón-Benedí, Ana Pascual-Bellosta, Sonia Ortega-Lucea, Javier Martinez-Ubieto","doi":"10.1002/lary.31976","DOIUrl":"https://doi.org/10.1002/lary.31976","url":null,"abstract":"","PeriodicalId":49921,"journal":{"name":"Laryngoscope","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143014845","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
18F-FDG PET/CT for Surveillance in Salivary Gland Cancers: A Systematic Review and Meta-Analysis. 18F-FDG PET/CT监测唾液腺癌:系统回顾和荟萃分析。
IF 2.2 3区 医学
Laryngoscope Pub Date : 2025-01-16 DOI: 10.1002/lary.32003
Emily Ajit-Roger, Keith Richardson, Alex Marcin Mlynarek, Nader Sadeghi, Michael P Hier, Marco A Mascarella
{"title":"18F-FDG PET/CT for Surveillance in Salivary Gland Cancers: A Systematic Review and Meta-Analysis.","authors":"Emily Ajit-Roger, Keith Richardson, Alex Marcin Mlynarek, Nader Sadeghi, Michael P Hier, Marco A Mascarella","doi":"10.1002/lary.32003","DOIUrl":"https://doi.org/10.1002/lary.32003","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the diagnostic accuracy of 18F-FDG-PET/CT compared to conventional imaging modalities (CIM) to detect recurrence of primary salivary gland cancers (SGCs).</p><p><strong>Data sources: </strong>Review performed on December 26, 2024, using Embase, CINHAL, MEDLINE, and PubMed.</p><p><strong>Review methods: </strong>Two blinded reviewers selected studies reporting diagnostic accuracy of PET/CT in identifying locoregional recurrence and/or metastasis in patients with SGCs. The analysis was performed adhering to PRISMA guidelines using R 4.3.3. Pooled analysis with 95% confidence intervals (CI) were analyzed.</p><p><strong>Results: </strong>A total of 12 studies were retained from the systematic review, including 264 patients evaluated in the meta-analysis. For local recurrence, there was a pooled sensitivity of 0.86 (95% CI 0.73-0.93) and a pooled specificity of 0.95 (95% CI 0.92-0.97) for PET/CT, and a pooled sensitivity of 0.89 (95% CI 0.80-0.94) and a pooled specificity of 0.91 (95% CI 0.79-0.97) for CIM (p = 0.90). For regional metastasis, there was a pooled sensitivity of 0.90 (95% CI 0.73-0.97) and a pooled specificity of 0.96 (95% CI 0.92-0.98) for PET/CT, and a pooled sensitivity of 0.80 (95% CI 0.62-0.91) and a pooled specificity of 0.95 (0.90-0.98) for CIM (p = 0.26). For distant metastasis, there was a pooled sensitivity of 0.96 (95% CI 0.90-0.99) and a pooled specificity of 0.95 (95% CI 0.85-0.98) for PET/CT, and a pooled sensitivity of 0.80 (95% CI 0.71-0.86) and a pooled specificity of 0.97 (95% CI 0.87-0.99) for CIM (p = 0.018).</p><p><strong>Conclusions: </strong>18F-FDG-PET/CT imaging is accurate for the detection of SGC recurrence, particularly for the detection of regional and distant metastases.</p><p><strong>Level of evidence: </strong>Not applicable Laryngoscope, 2025.</p>","PeriodicalId":49921,"journal":{"name":"Laryngoscope","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143015246","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Open Partial Horizontal Laryngectomy in the Elderly: Oncological and Functional Outcomes. 老年人开放性部分水平喉切除术:肿瘤和功能结果。
IF 2.2 3区 医学
Laryngoscope Pub Date : 2025-01-15 DOI: 10.1002/lary.31981
Andy Bertolin, Giovanni Succo, Erika Crosetti, Chiara Varago, Elisa Laura, Leonardo Franz, Thi K H Nguyen, Alessandra Di Chicco, Veronica Battistuzzi, Alberto Grassetto, Marco Lionello
{"title":"Open Partial Horizontal Laryngectomy in the Elderly: Oncological and Functional Outcomes.","authors":"Andy Bertolin, Giovanni Succo, Erika Crosetti, Chiara Varago, Elisa Laura, Leonardo Franz, Thi K H Nguyen, Alessandra Di Chicco, Veronica Battistuzzi, Alberto Grassetto, Marco Lionello","doi":"10.1002/lary.31981","DOIUrl":"https://doi.org/10.1002/lary.31981","url":null,"abstract":"<p><strong>Objectives: </strong>The aim of the present study was to investigate the oncological and functional prognostic implication of perioperative risk factors in the elderly patient who underwent open partial horizontal laryngectomy (OPHL).</p><p><strong>Study design: </strong>A single institution, retrospective case-cohort study.</p><p><strong>Methods: </strong>The present study retrospectively reviewed the clinical charts of a cohort of 100 elderly laryngeal squamous cell carcinoma (LSCC) patients who underwent OPHL at our institution. Oncological and functional results were evaluated through univariate analysis.</p><p><strong>Results: </strong>The overall recurrence rate was 19%. The 2 years overall and disease-specific survivals were 72% and 90%, respectively. No perioperative deaths were reported. A postoperative complication was reported in 20 cases (20%). Fifty-four patients (54%) were decannulated during the hospitalization. A percutaneous endoscopic gastrostomy procedure was performed in 12 patients (12%) due to persistent dysphagia. Twenty-six patients experienced postoperative late sequelae (26%), in terms of postoperative laryngeal obstruction (POLO) in 17 cases. A total of 80 patients (80%) were finally successfully decannulated. A functional total laryngectomy was performed in 6 cases.</p><p><strong>Conclusions: </strong>The indication to OPHL should be carefully evaluated in the elderly. In appropriately selected patient, OPHL represents a safe and effective therapeutic option. Cervical positive nodes and an incomplete resection of the tumor with positive surgical margins remain in such population the main prognostic factors for the oncological outcome, these factors have a negative impact on the functional outcome too, due to the need for adjuvant treatment. Hence, OPHL should be offered as a single-modality treatment especially in the elderly.</p><p><strong>Level of evidence: </strong>4 Laryngoscope, 2025.</p>","PeriodicalId":49921,"journal":{"name":"Laryngoscope","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142985165","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The impact of surgical margins in managing regional metastases in cutaneous squamous cell carcinoma of the head and neck. 手术切缘对头颈部皮肤鳞状细胞癌区域转移的影响。
IF 2.2 3区 医学
Laryngoscope Pub Date : 2025-01-15 DOI: 10.1002/lary.32006
Rachel Braude, Timothy G H Manzie, Jonathan R Clark, Kerwin Shannon, Carsten E Palme, Michael Elliott, James Wykes, Sydney Ch'ng, Ruta Gupta, Veronica Cheung, Tsu-Hui Low
{"title":"The impact of surgical margins in managing regional metastases in cutaneous squamous cell carcinoma of the head and neck.","authors":"Rachel Braude, Timothy G H Manzie, Jonathan R Clark, Kerwin Shannon, Carsten E Palme, Michael Elliott, James Wykes, Sydney Ch'ng, Ruta Gupta, Veronica Cheung, Tsu-Hui Low","doi":"10.1002/lary.32006","DOIUrl":"https://doi.org/10.1002/lary.32006","url":null,"abstract":"<p><strong>Background: </strong>Regional metastasis occurs in 5% of cutaneous squamous cell carcinoma (cSCC). The aim of this study is to assess the impact of margin status of regional metastases on survival.</p><p><strong>Methods: </strong>A retrospective review of 401 patients with nodal metastases from cSCC. Margin status of nodal metastases was classified as clear (>1 mm), close (<1 mm), or involved. Cox regression and Kaplan-Meier methods were used to assess associations with overall and disease-specific survival (OS and DSS).</p><p><strong>Results: </strong>Of the 401 patients with nodal metastases (median age 75, 85.3% male), 43.6% had involved margins, 27.4% had close margins, and 28.9% had clear margins. Involved margins were significantly associated with reduced OS and DSS on univariable analysis. Multivariable analysis confirmed that involved margins independently predicted worse DSS (HR 1.92, 95% CI 1.15-3.19, p = 0.01). Other independent prognostic factors included size of deposit (HR 1.02, 95% CI 1.01-1.04, p < 0.001), number of deposits (HR 1.05, 95% CI 1.02-1.08, p < 0.001), and the presence of perineural invasion (HR 1.84, 95% CI 1.14-2.98, p = 0.01).</p><p><strong>Conclusions: </strong>Clear surgical margins during the removal of regional metastases of cSCC improves survival outcomes. This study highlights the importance of careful preoperative evaluation to achieve a complete (R0) surgical resection.</p><p><strong>Level of evidence: </strong>Level 3 Laryngoscope, 2025.</p>","PeriodicalId":49921,"journal":{"name":"Laryngoscope","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142985170","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparing Otolaryngology Subspecialties' Changes in Medicare Reimbursement From 2013 to 2024. 比较2013 - 2024年耳鼻喉科亚专科医保报销的变化。
IF 2.2 3区 医学
Laryngoscope Pub Date : 2025-01-15 DOI: 10.1002/lary.31978
Alexander Dorius, Wesley Allen, Carson Bateman, Joshua Demke, Winslo Idicula
{"title":"Comparing Otolaryngology Subspecialties' Changes in Medicare Reimbursement From 2013 to 2024.","authors":"Alexander Dorius, Wesley Allen, Carson Bateman, Joshua Demke, Winslo Idicula","doi":"10.1002/lary.31978","DOIUrl":"https://doi.org/10.1002/lary.31978","url":null,"abstract":"<p><strong>Objective: </strong>Identify differences in Medicare reimbursement changes for general otolaryngology, pediatric otolaryngology, head and neck oncology, laryngology, rhinology, otology, facial plastic and reconstructive surgery, and sleep surgery subspecialties from 2013 to 2024.</p><p><strong>Methods: </strong>Subspecialty-based procedures' facility prices and relative value units (RVUs) were sourced from the Centers for Medicare & Medicaid Services' Physician Fee Schedule. Prices were adjusted for inflation, and the average percent change in facility price and RVUs for each subspecialty was calculated. Each subspecialty's average inflation-adjusted, facility price change was compared to general otolaryngology using t-tests, and differences between subspecialties were assessed using Dunn's test.</p><p><strong>Results: </strong>From 2013 to 2024, general otolaryngology's average percent change was -29.9% and significantly differed from facial plastic and reconstructive surgery (-26.4% [-5.5 to -0.7%]; p = 0.011) and sleep surgery (-23.7% [-19.2 to -2.2%]; p = 0.016). Rhinology (-32.5% [-1.3 to 6.1%]), otology (-30.2% [-6.5 to 7.6%]), laryngology (-29.3 [-4.2 to 2.1%]), head and neck (-27.4% [-5.7 to 0.2%]), and pediatric otolaryngology (-25.8% [-14.6 to 3.8%]) also decreased drastically but were not significantly different from general otolaryngology. For the multiple comparisons test, rhinology was statistically different from sleep surgery and facial plastic and reconstructive surgery.</p><p><strong>Conclusion: </strong>General otolaryngology and rhinology were more negatively affected due to changes in work and practice expense RVUs. Universal decreases were due to inflation and legislative reductions to the conversion factor. Medicare's budget constraints, potential effects on access to otolaryngology services, and continuing inflation warrant lobbying efforts to address these changes to maintain financial viability.</p><p><strong>Level of evidence: </strong>NA Laryngoscope, 2025.</p>","PeriodicalId":49921,"journal":{"name":"Laryngoscope","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142985157","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Correction to “Quality of Life in Symptomatic Septal Perforation” 对“症状性鼻中隔穿孔患者的生活质量”的修正。
IF 2.2 3区 医学
Laryngoscope Pub Date : 2025-01-12 DOI: 10.1002/lary.31875
{"title":"Correction to “Quality of Life in Symptomatic Septal Perforation”","authors":"","doi":"10.1002/lary.31875","DOIUrl":"10.1002/lary.31875","url":null,"abstract":"<p>Alegre Edo B, Rojas-Lechuga MJ, Quer-Castells M, González-Sánchez N, Lopez-Chacon M, Hopkins C, Alobid I. Quality of life in symptomatic septal perforation. Laryngoscope 2024;134(11):4480–4487. https://doi.org/10.1002/lary.31557</p><p>The authors have identified the following errors in Tables II and III and would like to correct them.</p><p>In Table II, titled “Comparison of the Mean SNOT-22 Questionnaire Score by Domains in CRSwNP and SP,” in the data in the top row, second column, the value “46.5 (22.0)*” should be replaced with “42.4 (24.4)*” and in the data in the top row, third column, the value “42.4 (24.4)*” should be replaced with “46.5 (22.0)*.” Also, the <i>p</i>-Value in the fourth column of the top row, “<i>p</i> &lt; 0.001,” should be replaced with “<i>p</i> = 0.264.”</p><p>In Table III, “Comparison of the SNOT-22 Questionnaire Score by Items Between the Three Groups Expressed as a Percentage,” in the first column, the text “3. Think nasal discharge” should be replaced with “3. Runny nose” and the text “6. Runny nose” should be replaced with “6. Thick nasal discharge.”</p><p>We apologize for this error.</p>","PeriodicalId":49921,"journal":{"name":"Laryngoscope","volume":"135 2","pages":"969"},"PeriodicalIF":2.2,"publicationDate":"2025-01-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/lary.31875","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142973001","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Transoral Laser Microsurgery Versus Radiotherapy for T1-T2 Glottic Cancer with Anterior Commissure Involvement: A Systematic Review and Meta-Analysis. 经口激光显微手术与放疗治疗累及前联合的T1-T2声门癌:一项系统综述和荟萃分析。
IF 2.2 3区 医学
Laryngoscope Pub Date : 2025-01-11 DOI: 10.1002/lary.32005
Srivatsa Surya Vasudevan, Elizabeth Bryan, Elise Ericksen, Anika Alla, Ameya A Asarkar, Lindsay Olinde, Sanford Katz, Cherie-Ann O Nathan
{"title":"Transoral Laser Microsurgery Versus Radiotherapy for T1-T2 Glottic Cancer with Anterior Commissure Involvement: A Systematic Review and Meta-Analysis.","authors":"Srivatsa Surya Vasudevan, Elizabeth Bryan, Elise Ericksen, Anika Alla, Ameya A Asarkar, Lindsay Olinde, Sanford Katz, Cherie-Ann O Nathan","doi":"10.1002/lary.32005","DOIUrl":"https://doi.org/10.1002/lary.32005","url":null,"abstract":"<p><strong>Objective: </strong>To identify the most effective treatment modality for achieving favorable outcomes in early glottic tumors with anterior commissure involvement (ACI).</p><p><strong>Data sources: </strong>PubMed, Embase, Web of Science, and ScienceDirect.</p><p><strong>Review methods: </strong>Random-effects proportional meta-analysis model is used to evaluate the oncological and functional outcomes of transoral laser microsurgery (TLM) versus radiation therapy (RT) in early glottic (T1-T2) cancer with ACI.</p><p><strong>Results: </strong>From a total of 736 studies, 40 studies were included, comprising 2666 early glottic tumor patients with ACI. TLM (52%) and upfront RT (48%) were the primary treatment groups. TLM had better 5-year overall survival (OS) (84.5% [80.3%-88.0%] vs. 79.4% [75.7%-82.7%]). Similarly, TLM-treated patients had better 3-year pooled disease-free survival (DFS) compared with RT-treated patients (82.7% [77.1%-87.1%] vs. 73.3% [23.8%-96.0%]). TLM exhibited a better 5-year local control rate (LCR) than RT (77.2% vs. 71.6%). In our temporal analysis, TLM had a higher 5-year LCR than RT (78.2% vs. 63.5%) in 2001-2012, with similar rates in 2013-2024 (76.8% vs. 78.4%). TLM-treated patients had higher laryngeal preservation rates compared with RT patients (93% [90.6%-94.8%] vs. 87.6% [82.8%-91.2%]).</p><p><strong>Conclusions: </strong>Our meta-analysis is the first in the literature to compare the outcomes between TLM and RT-treated patients with ACI in early glottic tumors. TLM-treated patients appear to have superior 5-year OS and laryngeal preservation compared with upfront RT-treated patients. However, both TLM and RT exhibited comparable oncological outcomes in early glottic tumor patients with ACI during the recent period from 2013 to 2024. Laryngoscope, 2025.</p>","PeriodicalId":49921,"journal":{"name":"Laryngoscope","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-01-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142967364","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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