Lifetime Data Analysis最新文献

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Unifying mortality forecasting model: an investigation of the COM–Poisson distribution in the GAS model for improved projections 统一死亡率预测模型:为改进预测而对 GAS 模型中 COM-Poisson 分布的研究
IF 1.3 3区 数学
Lifetime Data Analysis Pub Date : 2024-09-13 DOI: 10.1007/s10985-024-09634-x
Suryo Adi Rakhmawan, Tahir Mahmood, Nasir Abbas, Muhammad Riaz
{"title":"Unifying mortality forecasting model: an investigation of the COM–Poisson distribution in the GAS model for improved projections","authors":"Suryo Adi Rakhmawan, Tahir Mahmood, Nasir Abbas, Muhammad Riaz","doi":"10.1007/s10985-024-09634-x","DOIUrl":"https://doi.org/10.1007/s10985-024-09634-x","url":null,"abstract":"<p>Forecasting mortality rates is crucial for evaluating life insurance company solvency, especially amid disruptions caused by phenomena like COVID-19. The Lee–Carter model is commonly employed in mortality modelling; however, extensions that can encompass count data with diverse distributions, such as the Generalized Autoregressive Score (GAS) model utilizing the COM–Poisson distribution, exhibit potential for enhancing time-to-event forecasting accuracy. Using mortality data from 29 countries, this research evaluates various distributions and determines that the COM–Poisson model surpasses the Poisson, binomial, and negative binomial distributions in forecasting mortality rates. The one-step forecasting capability of the GAS model offers distinct advantages, while the COM–Poisson distribution demonstrates enhanced flexibility and versatility by accommodating various distributions, including Poisson and negative binomial. Ultimately, the study determines that the COM–Poisson GAS model is an effective instrument for examining time series data on mortality rates, particularly when facing time-varying parameters and non-conventional data distributions.</p>","PeriodicalId":49908,"journal":{"name":"Lifetime Data Analysis","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2024-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142220139","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"数学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Nested case-control sampling without replacement. 无替换的嵌套病例对照抽样。
IF 1.2 3区 数学
Lifetime Data Analysis Pub Date : 2024-09-05 DOI: 10.1007/s10985-024-09633-y
Yei Eun Shin, Takumi Saegusa
{"title":"Nested case-control sampling without replacement.","authors":"Yei Eun Shin, Takumi Saegusa","doi":"10.1007/s10985-024-09633-y","DOIUrl":"https://doi.org/10.1007/s10985-024-09633-y","url":null,"abstract":"<p><p>Nested case-control design (NCC) is a cost-effective outcome-dependent design in epidemiology that collects all cases and a fixed number of controls at the time of case diagnosis from a large cohort. Due to inefficiency relative to full cohort studies, previous research developed various estimation methodologies but changing designs in the formulation of risk sets was considered only in view of potential bias in the partial likelihood estimation. In this paper, we study a modified design that excludes previously selected controls from risk sets in view of efficiency improvement as well as bias. To this end, we extend the inverse probability weighting method of Samuelsen which was shown to outperform the partial likelihood estimator in the standard setting. We develop its asymptotic theory and a variance estimation of both regression coefficients and the cumulative baseline hazard function that takes account of the complex feature of the modified sampling design. In addition to good finite sample performance of variance estimation, simulation studies show that the modified design with the proposed estimator is more efficient than the standard design. Examples are provided using data from NIH-AARP Diet and Health Cohort Study.</p>","PeriodicalId":49908,"journal":{"name":"Lifetime Data Analysis","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142134285","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"数学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Copula-based analysis of dependent current status data with semiparametric linear transformation model. 利用半参数线性变换模型对依赖性时态数据进行基于 Copula 的分析。
IF 1.2 3区 数学
Lifetime Data Analysis Pub Date : 2024-08-24 DOI: 10.1007/s10985-024-09632-z
Huazhen Yu, Rui Zhang, Lixin Zhang
{"title":"Copula-based analysis of dependent current status data with semiparametric linear transformation model.","authors":"Huazhen Yu, Rui Zhang, Lixin Zhang","doi":"10.1007/s10985-024-09632-z","DOIUrl":"https://doi.org/10.1007/s10985-024-09632-z","url":null,"abstract":"<p><p>This paper discusses regression analysis of current status data with dependent censoring, a problem that often occurs in many areas such as cross-sectional studies, epidemiological investigations and tumorigenicity experiments. Copula model-based methods are commonly employed to tackle this issue. However, these methods often face challenges in terms of model and parameter identification. The primary aim of this paper is to propose a copula-based analysis for dependent current status data, where the association parameter is left unspecified. Our method is based on a general class of semiparametric linear transformation models and parametric copulas. We demonstrate that the proposed semiparametric model is identifiable under certain regularity conditions from the distribution of the observed data. For inference, we develop a sieve maximum likelihood estimation method, using Bernstein polynomials to approximate the nonparametric functions involved. The asymptotic consistency and normality of the proposed estimators are established. Finally, to demonstrate the effectiveness and practical applicability of our method, we conduct an extensive simulation study and apply the proposed method to a real data example.</p>","PeriodicalId":49908,"journal":{"name":"Lifetime Data Analysis","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142047379","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"数学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Special issue dedicated to Mitchell H. Gail, M.D. Ph.D. 米切尔-盖尔医学博士特刊
IF 1.2 3区 数学
Lifetime Data Analysis Pub Date : 2024-07-01 Epub Date: 2024-06-24 DOI: 10.1007/s10985-024-09631-0
Mei-Ling Ting Lee
{"title":"Special issue dedicated to Mitchell H. Gail, M.D. Ph.D.","authors":"Mei-Ling Ting Lee","doi":"10.1007/s10985-024-09631-0","DOIUrl":"10.1007/s10985-024-09631-0","url":null,"abstract":"","PeriodicalId":49908,"journal":{"name":"Lifetime Data Analysis","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141443608","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"数学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A constrained maximum likelihood approach to developing well-calibrated models for predicting binary outcomes. 开发校准良好的二元结果预测模型的受限最大似然法。
IF 1.2 3区 数学
Lifetime Data Analysis Pub Date : 2024-07-01 Epub Date: 2024-05-08 DOI: 10.1007/s10985-024-09628-9
Yaqi Cao, Weidong Ma, Ge Zhao, Anne Marie McCarthy, Jinbo Chen
{"title":"A constrained maximum likelihood approach to developing well-calibrated models for predicting binary outcomes.","authors":"Yaqi Cao, Weidong Ma, Ge Zhao, Anne Marie McCarthy, Jinbo Chen","doi":"10.1007/s10985-024-09628-9","DOIUrl":"10.1007/s10985-024-09628-9","url":null,"abstract":"<p><p>The added value of candidate predictors for risk modeling is routinely evaluated by comparing the performance of models with or without including candidate predictors. Such comparison is most meaningful when the estimated risk by the two models are both unbiased in the target population. Very often data for candidate predictors are sourced from nonrepresentative convenience samples. Updating the base model using the study data without acknowledging the discrepancy between the underlying distribution of the study data and that in the target population can lead to biased risk estimates and therefore an unfair evaluation of candidate predictors. To address this issue assuming access to a well-calibrated base model, we propose a semiparametric method for model fitting that enforces good calibration. The central idea is to calibrate the fitted model against the base model by enforcing suitable constraints in maximizing the likelihood function. This approach enables unbiased assessment of model improvement offered by candidate predictors without requiring a representative sample from the target population, thus overcoming a significant practical challenge. We study theoretical properties for model parameter estimates, and demonstrate improvement in model calibration via extensive simulation studies. Finally, we apply the proposed method to data extracted from Penn Medicine Biobank to inform the added value of breast density for breast cancer risk assessment in the Caucasian woman population.</p>","PeriodicalId":49908,"journal":{"name":"Lifetime Data Analysis","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140877759","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"数学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Competing risks and multivariate outcomes in epidemiological and clinical trial research. 流行病学和临床试验研究中的竞争风险和多变量结果。
IF 1.2 3区 数学
Lifetime Data Analysis Pub Date : 2024-07-01 Epub Date: 2024-05-06 DOI: 10.1007/s10985-024-09629-8
R L Prentice
{"title":"Competing risks and multivariate outcomes in epidemiological and clinical trial research.","authors":"R L Prentice","doi":"10.1007/s10985-024-09629-8","DOIUrl":"10.1007/s10985-024-09629-8","url":null,"abstract":"<p><p>Data analysis methods for the study of treatments or exposures in relation to a clinical outcome in the presence of competing risks have a long history, often with inference targets that are hypothetical, thereby requiring strong assumptions for identifiability with available data. Here data analysis methods are considered that are based on single and higher dimensional marginal hazard rates, quantities that are identifiable under standard independent censoring assumptions. These lead naturally to joint survival function estimators for outcomes of interest, including competing risk outcomes, and provide the basis for addressing a variety of data analysis questions. These methods will be illustrated using simulations and Women's Health Initiative cohort and clinical trial data sets, and additional research needs will be described.</p>","PeriodicalId":49908,"journal":{"name":"Lifetime Data Analysis","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140858787","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"数学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Bayesian quantile joint modeling of multivariate longitudinal and time-to-event data. 多变量纵向和时间到事件数据的贝叶斯量化联合建模。
IF 1.2 3区 数学
Lifetime Data Analysis Pub Date : 2024-07-01 Epub Date: 2024-03-01 DOI: 10.1007/s10985-024-09622-1
Damitri Kundu, Shekhar Krishnan, Manash Pratim Gogoi, Kiranmoy Das
{"title":"A Bayesian quantile joint modeling of multivariate longitudinal and time-to-event data.","authors":"Damitri Kundu, Shekhar Krishnan, Manash Pratim Gogoi, Kiranmoy Das","doi":"10.1007/s10985-024-09622-1","DOIUrl":"10.1007/s10985-024-09622-1","url":null,"abstract":"<p><p>Linear mixed models are traditionally used for jointly modeling (multivariate) longitudinal outcomes and event-time(s). However, when the outcomes are non-Gaussian a quantile regression model is more appropriate. In addition, in the presence of some time-varying covariates, it might be of interest to see how the effects of different covariates vary from one quantile level (of outcomes) to the other, and consequently how the event-time changes across different quantiles. For such analyses linear quantile mixed models can be used, and an efficient computational algorithm can be developed. We analyze a dataset from the Acute Lymphocytic Leukemia (ALL) maintenance study conducted by Tata Medical Center, Kolkata. In this study, the patients suffering from ALL were treated with two standard drugs (6MP and MTx) for the first two years, and three biomarkers (e.g. lymphocyte count, neutrophil count and platelet count) were longitudinally measured. After treatment the patients were followed nearly for the next three years, and the relapse-time (if any) for each patient was recorded. For this dataset we develop a Bayesian quantile joint model for the three longitudinal biomarkers and time-to-relapse. We consider an Asymmetric Laplace Distribution (ALD) for each outcome, and exploit the mixture representation of the ALD for developing a Gibbs sampler algorithm to estimate the regression coefficients. Our proposed model allows different quantile levels for different biomarkers, but still simultaneously estimates the regression coefficients corresponding to a particular quantile combination. We infer that a higher lymphocyte count accelerates the chance of a relapse while a higher neutrophil count and a higher platelet count (jointly) reduce it. Also, we infer that across (almost) all quantiles 6MP reduces the lymphocyte count, while MTx increases the neutrophil count. Simulation studies are performed to assess the effectiveness of the proposed approach.</p>","PeriodicalId":49908,"journal":{"name":"Lifetime Data Analysis","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139998108","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"数学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
On the role of Volterra integral equations in self-consistent, product-limit, inverse probability of censoring weighted, and redistribution-to-the-right estimators for the survival function. 论 Volterra 积分方程在生存函数的自洽、乘积限制、反删减概率加权和向右再分布估计器中的作用。
IF 1.2 3区 数学
Lifetime Data Analysis Pub Date : 2024-07-01 Epub Date: 2024-03-21 DOI: 10.1007/s10985-024-09623-0
Robert L Strawderman, Benjamin R Baer
{"title":"On the role of Volterra integral equations in self-consistent, product-limit, inverse probability of censoring weighted, and redistribution-to-the-right estimators for the survival function.","authors":"Robert L Strawderman, Benjamin R Baer","doi":"10.1007/s10985-024-09623-0","DOIUrl":"10.1007/s10985-024-09623-0","url":null,"abstract":"<p><p>This paper reconsiders several results of historical and current importance to nonparametric estimation of the survival distribution for failure in the presence of right-censored observation times, demonstrating in particular how Volterra integral equations help inter-connect the resulting estimators. The paper begins by considering Efron's self-consistency equation, introduced in a seminal 1967 Berkeley symposium paper. Novel insights provided in the current work include the observations that (i) the self-consistency equation leads directly to an anticipating Volterra integral equation whose solution is given by a product-limit estimator for the censoring survival function; (ii) a definition used in this argument immediately establishes the familiar product-limit estimator for the failure survival function; (iii) the usual Volterra integral equation for the product-limit estimator of the failure survival function leads to an immediate and simple proof that it can be represented as an inverse probability of censoring weighted estimator; (iv) a simple identity characterizes the relationship between natural inverse probability of censoring weighted estimators for the survival and distribution functions of failure; (v) the resulting inverse probability of censoring weighted estimators, attributed to a highly influential 1992 paper of Robins and Rotnitzky, were implicitly introduced in Efron's 1967 paper in its development of the redistribution-to-the-right algorithm. All results developed herein allow for ties between failure and/or censored observations.</p>","PeriodicalId":49908,"journal":{"name":"Lifetime Data Analysis","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140186140","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"数学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Risk projection for time-to-event outcome from population-based case-control studies leveraging summary statistics from the target population. 利用目标人群的汇总统计数据,对基于人群的病例对照研究的时间到事件结果进行风险预测。
IF 1.2 3区 数学
Lifetime Data Analysis Pub Date : 2024-07-01 Epub Date: 2024-05-28 DOI: 10.1007/s10985-024-09626-x
Jiayin Zheng, Li Hsu
{"title":"Risk projection for time-to-event outcome from population-based case-control studies leveraging summary statistics from the target population.","authors":"Jiayin Zheng, Li Hsu","doi":"10.1007/s10985-024-09626-x","DOIUrl":"10.1007/s10985-024-09626-x","url":null,"abstract":"<p><p>Risk stratification based on prediction models has become increasingly important in preventing and managing chronic diseases. However, due to cost- and time-limitations, not every population can have resources for collecting enough detailed individual-level information on a large number of people to develop risk prediction models. A more practical approach is to use prediction models developed from existing studies and calibrate them with relevant summary-level information of the target population. Many existing studies were conducted under the population-based case-control design. Gail et al. (J Natl Cancer Inst 81:1879-1886, 1989) proposed to combine the odds ratio estimates obtained from case-control data and the disease incidence rates from the target population to obtain the baseline hazard function, and thereby the pure risk for developing diseases. However, the approach requires the risk factor distribution of cases from the case-control studies be same as the target population, which, if violated, may yield biased risk estimation. In this article, we propose two novel weighted estimating equation approaches to calibrate the baseline risk by leveraging the summary information of (some) risk factors in addition to disease-free probabilities from the targeted population. We establish the consistency and asymptotic normality of the proposed estimators. Extensive simulation studies and an application to colorectal cancer studies demonstrate the proposed estimators perform well for bias reduction in finite samples.</p>","PeriodicalId":49908,"journal":{"name":"Lifetime Data Analysis","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11283322/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141158740","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"数学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Measurement error models with zero inflation and multiple sources of zeros, with applications to hard zeros. 零膨胀和多源零的测量误差模型,以及对硬零的应用。
IF 1.2 3区 数学
Lifetime Data Analysis Pub Date : 2024-07-01 Epub Date: 2024-05-28 DOI: 10.1007/s10985-024-09627-w
Anindya Bhadra, Rubin Wei, Ruth Keogh, Victor Kipnis, Douglas Midthune, Dennis W Buckman, Ya Su, Ananya Roy Chowdhury, Raymond J Carroll
{"title":"Measurement error models with zero inflation and multiple sources of zeros, with applications to hard zeros.","authors":"Anindya Bhadra, Rubin Wei, Ruth Keogh, Victor Kipnis, Douglas Midthune, Dennis W Buckman, Ya Su, Ananya Roy Chowdhury, Raymond J Carroll","doi":"10.1007/s10985-024-09627-w","DOIUrl":"10.1007/s10985-024-09627-w","url":null,"abstract":"<p><p>We consider measurement error models for two variables observed repeatedly and subject to measurement error. One variable is continuous, while the other variable is a mixture of continuous and zero measurements. This second variable has two sources of zeros. The first source is episodic zeros, wherein some of the measurements for an individual may be zero and others positive. The second source is hard zeros, i.e., some individuals will always report zero. An example is the consumption of alcohol from alcoholic beverages: some individuals consume alcoholic beverages episodically, while others never consume alcoholic beverages. However, with a small number of repeat measurements from individuals, it is not possible to determine those who are episodic zeros and those who are hard zeros. We develop a new measurement error model for this problem, and use Bayesian methods to fit it. Simulations and data analyses are used to illustrate our methods. Extensions to parametric models and survival analysis are discussed briefly.</p>","PeriodicalId":49908,"journal":{"name":"Lifetime Data Analysis","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141162786","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"数学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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