{"title":"Antibacterial Effects of Garlic Ethyl Acetate Fraction (Allium Sativum L.) on the Growth Of Bacteria Staphylococcus aureus and Escherichia coli","authors":"Larasati Juninda, Listiana Masyita Dewi, Retno Sintowati, Rochmadina Suci Bestari","doi":"10.26714/magnamed.10.2.2023.163-169","DOIUrl":"https://doi.org/10.26714/magnamed.10.2.2023.163-169","url":null,"abstract":"Background: Antibiotics are a treatment used to treat bacterial infections. However, the many antibiotic-resistant bacteria caused researchers to use plants as an alternative treatment, one of which is garlic (Allium sativum L.).Objective: Previous research stated that the diameter of the inhibition zone by garlic had a more excellent value than the antibiotics used. Hence, the researchers were interested in conducting an antibacterial test of the ethyl acetate fraction of garlic against the growth of Staphylococcus aureus and Escherichia coli.Methods: This study was an experimental laboratory using the posttest-only control group design method in the Kruskal Wallis test data analysis.Results: the results of the inhibition analysis with p-value < 0.05 in each test group for both Staphylococcus aureus and Escherichia coli. With the Mann-Whitney test, the results obtained a p-value <0.005 for each bacteria and test group. The most significant value, namely p= 0.002. This result shows significant differences between the test groups for each bacterium.Conclusion: There is an antibacterial effect of the ethyl acetate fraction of garlic (Allium sativum L.) at concentrations of 25%, 50%, and 100% against the growth of Staphylococcus aureus and Escherichia coli","PeriodicalId":497782,"journal":{"name":"Magna Medica","volume":"71 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136045392","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Potential Ekstract Of Red Betel Leaf (Piper crocatum Ruiz & Pav.) as a Natural Hand Sanitizer","authors":"Maya Monica Manurung, Tyas Hanurita Subekti, Nanda Dhea Ayu Sawitri, Iin Novita Nurhidayati Mahmuda","doi":"10.26714/magnamed.10.2.2023.141-149","DOIUrl":"https://doi.org/10.26714/magnamed.10.2.2023.141-149","url":null,"abstract":"Background: Hands are the most common medium for spreading disease. Red betel leaf has antibacterial bioactive compounds such as flavonoids, alkaloids, polyphenols, tannins, and essential oils. The most common way to clean hands is to use hand sanitizer.Objective: To determine the antibacterial potential of red betel leaf extract (Piper crocatum Ruiz & Pav.) against the growth of Staphylococcus aureus, Streptococcus pyogenes, and Salmonella typhi as an active ingredient in hand sanitizers. Methods: Each bacterium, namely Staphylococus aureus, Streptococcus pyogenes and Salmonella typhi were divided into 6 groups, PEG 5% as a negative control, clindamycin for Staphylococus aureus and Streptococcus pyogenes and chloramphenicol for Salmonella typhi as a positive control, 70% alcohol as a comparison for hand sanitizer, extract 20%, 40%, and 80% as treatment groups. The obstacle zone is measured using a ruler.Results: Zones of inhibition against Staphylococus aureus, Streptococcus pyogenes, and Salmonella typhi were formed at concentrations of 20%, 40%, and 80%. Kruskal Wallis statistical analysis showed significant results with p=0.000.Conclusion: Red betel leaf extract has statistically significant antibacterial activity against Staphylococcus aureus, Streptococcus pyogenes and Salmonella typhi. The extract concentration of 40% is the optimal concentration as a raw material for hand sanitizer.","PeriodicalId":497782,"journal":{"name":"Magna Medica","volume":"129 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136045393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Magna MedicaPub Date : 2023-07-30DOI: 10.26714/magnamed.10.1.2023.129-140
Kornelis Aribowo, Wiwi Monica Sari
{"title":"Hematological Side Effects Management of Paclitaxel - Carboplatin Chemotherapy in Lung Cancer","authors":"Kornelis Aribowo, Wiwi Monica Sari","doi":"10.26714/magnamed.10.1.2023.129-140","DOIUrl":"https://doi.org/10.26714/magnamed.10.1.2023.129-140","url":null,"abstract":"Background: Paclitaxel-carboplatin chemotherapy can cause hema-tological disorders. This regiment's hematological side effects include anemia, neutropenia, and thrombocytopenia. Data showed this regiment side effect occurs with grade iii/iv toxicity anemia, grade III/IV anemia by 41%, neutropenia (78%), and thrombocytopenia (41%). This hema-tological disorder occurs in bone marrow-producing areas due to chemotherapy. Each hematological disorder requires separate interven-tion.Case Presentation: A 54-year-old woman was diagnosed with a progressive disease of left lung adenocarcinoma (Exon 21 mutation) with TKI and received paclitaxel-carboplatin chemotherapy. The patient experienced side effects of anemia, neutropenia, and thrombocytopenia. Anemia was treated with PRC transfusion, neutropenia corrected with Filgrastim, and thrombocytopenia with platelet transfusion. Chemo-therapy was discontinued after five cycles because the Thrombo-cytopenia condition did not improve.Conclusion: Hematological parameters are essential in preparing for lung cancer chemotherapy. Uncorrectable hematological disorders lead to discontinuation of chemotherapy","PeriodicalId":497782,"journal":{"name":"Magna Medica","volume":"82 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135398538","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Magna MedicaPub Date : 2023-07-30DOI: 10.26714/magnamed.10.1.2023.117-128
Ahmad Hannan, Khamim Thohari, Khofifah Dwi Oktafiana, Mohammad Hasan, Muhammad Hanun Mahyudin
{"title":"Multiple Trauma with Severe Brain Injury Cause by Impression Fracture : Case Report and Literature Review","authors":"Ahmad Hannan, Khamim Thohari, Khofifah Dwi Oktafiana, Mohammad Hasan, Muhammad Hanun Mahyudin","doi":"10.26714/magnamed.10.1.2023.117-128","DOIUrl":"https://doi.org/10.26714/magnamed.10.1.2023.117-128","url":null,"abstract":"Background : Multiple trauma one of trauma caused by huge traumatic force involves many organs and tissues. AIS and ISS is scoring for multiple trauma diagnosis and classification. In this Case Report discuss about multiple trauma patient with Severe Brain Injury cause by Impression Fracture with open fracture in regio cruris sinistra and close fracture femur sinistra. Case presentation : The following is a case report of a 63-year-old female patient came to the emergency room of Soegiri Lamongan with decreased of consciousness due to a traffic accident. Mechanism of injury the patient's head hit the chair and the driver's side of the car pillar and the patient's legs were pinched by the car seat. Since 25-year-old patient has a history of uncontrolled diabetes mellitus but the patient regularly takes anti-diabetic drugs (OAD). Patient was diagnosed with multiple trauma with severe brain injury with suspected DAI with open fracture grade 3A middle 1/3 tibia and close fracture middle 1/3 distal femur.Conclusion : Multiple Trauma has a bad prognosis. The most important from Multiple trauma management is prehospotality management. Additional Severe Brain Injury make the diagnosis become worse.","PeriodicalId":497782,"journal":{"name":"Magna Medica","volume":"51 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135398539","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Magna MedicaPub Date : 2023-02-01DOI: 10.26714/magnamed.10.1.2023.48-59
Wiwik Kusumawati, Romdzati Romdzati
{"title":"Collaborative Practice between Doctors and Nurses in Patients Management: Attitude of Teamwork","authors":"Wiwik Kusumawati, Romdzati Romdzati","doi":"10.26714/magnamed.10.1.2023.48-59","DOIUrl":"https://doi.org/10.26714/magnamed.10.1.2023.48-59","url":null,"abstract":"Background: Interprofessional collaboration is essential in providing higher-quality health services and ensuring patient safety.Objective: This study aims to assess the attitude of cooperation between doctors and nurses as first line health workers in an academic health facility and explore their perspectives on the collaboration attitude between doctors and nurses.Methods: This study used a mixed-method design. The quantitative sample was chosen randomly but with total sampling for the primary clinic. Data on the attitude of cooperation between doctors and nurses from the questionnaire results were analyzed descriptively. The sample for the qualitative study was selected purposively, each health service consisted of 1 doctor and one nurse, so the number of informants was six. The qualitative data were transcribed verbatim and analyzed qualitatively using the constant comparative method.Results: The results showed that of 84 respondents, 54 doctors, and 30 nurses, 95% showed a good teamwork attitude. Some respondents (5%) showed a bad attitude, especially on three items, namely item no 4 (doctors do not have the right to change the treatment plan that has been made), 13 (doctors do not have to be the final determinant) and 18 (possibility of other professions to become leaders). The results of the qualitative analysis show that there are five final themes, namely: 1. teamwork is good; 2. the role of the profession; 3. the importance of interprofessional communication; 4. openness to receive feedback; 5—patient safety and PCC.Conclusion: Both professions have distinct but equal and complementary roles in patient management, each with their own advantages or capabilities. Open communication, which includes getting criticism, can help overcome a poor cooperative attitude.","PeriodicalId":497782,"journal":{"name":"Magna Medica","volume":"23 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135202004","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Magna MedicaPub Date : 2023-02-01DOI: 10.26714/magnamed.10.1.2023.109-116
Priangga Adi Wiratama, Alphania Rahniayu, Vira Yasmina Ramadhani
{"title":"Mature Teratoma of The Lung : A Case Report","authors":"Priangga Adi Wiratama, Alphania Rahniayu, Vira Yasmina Ramadhani","doi":"10.26714/magnamed.10.1.2023.109-116","DOIUrl":"https://doi.org/10.26714/magnamed.10.1.2023.109-116","url":null,"abstract":"Background: Mature teratoma is a germinal cell tumor that is commonly found in ovaries and testis. Mature teratoma in the lung region is a rare case. According to the literature there are only 67 cases worldwide starting from 1939 to 2007. There were one cases in Dr. Soetomo general hospital during January 2013 – December 2017.Objective: Mature teratoma in the lung region is a rare case. Presenting in a case report would be beneficial for pathology databaseCase Presentation: A 19 years old man came to hospital with shortness of breath within 3 months ago. It was followed with hemoptysis, trichoptysis and coughing out tooth. CT Scan examination showed an irregular walled cavity with semisolid component and calcification along with a description of \"air cresent sign\". In thoracotomy tumor excision obtained multilobulated mass size 8.5x6,8x5,6 cm, yellowish-gray white color, and firm consistency. There were also hair and tooth components. The microscopic representation shows pieces of lung tissue with tumor growth coated with squamous epithel with a stroma containing adnexal skin glands, fatty tissue, cartilage tissue, and serous glands (asinar). Discussion: Mature teratoma of the lung is one of the rare tumors, with symptoms of chest pain, hemoptysis, and trichoptysis. Mature teratoma of the lung is generally cystic and multiloculated, but can also be solid, encapsulated. On microscopic examination, shows a picture of various components of ectoderm, mesoderm and endoderm.Conclusion: Mature teratoma of the lung is a rare tumor. Diagnosis was based from clinical findings, radiologic examination, and confirmed with histopathology and immunohistochemistry.","PeriodicalId":497782,"journal":{"name":"Magna Medica","volume":"239 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135202210","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Magna MedicaPub Date : 2023-02-01DOI: 10.26714/magnamed.10.1.2023.19-26
Vika Pangesty, Ika Dyah Kurniati, Kanti Ratnaningrum
{"title":"Effectiveness of Bitter melon (Momordica charantia L) Extract on Growth of Trichopyton rubrum: In Vitro Study","authors":"Vika Pangesty, Ika Dyah Kurniati, Kanti Ratnaningrum","doi":"10.26714/magnamed.10.1.2023.19-26","DOIUrl":"https://doi.org/10.26714/magnamed.10.1.2023.19-26","url":null,"abstract":"Trichophyton rubrum is type of fungus that most often causes superficial fungal infections. Development of herbal ingredients as antifungal therapy is carried out to find alternative therapies for fungal infections. Bitter melon contains various compounds that have potential to be used as antifungals, including flavonoids and saponins. The aim of this study was to determine the effect of bitter melon extract (Momordica charantia L) on the growth of Trichopyton rubrum. This study used bitter melon extract at concentrations of 5%, 25%, 50%, 75% and 100%. Ketoconazole concentrations of 2% was used as a positive control. Pure cultures of Trichopyton rubrum were diluted using physiological NaCl. Fungal growth was observed microscopically and macroscopically. Results showed that Trichopyton rubrum grew at a concentration of 5% while at concentrations of 25%, 50%, 75% and 100% there was no Trichopyton rubrum growth. Bitter melon extract at a concentration of 25% had similar effect as ketoconazole 2%. Conclusion Bitter melon extract at concentrations of 25%, 50%, 75% and 100% had a similar effect to 2% ketoconazole in inhibiting the growth of Tricophyton rubrum.","PeriodicalId":497782,"journal":{"name":"Magna Medica","volume":"26 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135202003","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Magna MedicaPub Date : 2023-02-01DOI: 10.26714/magnamed.10.1.2023.60-66
Izza Alya Ardana Putri, Astin Prima Sari, Ika Dyah Kurniati
{"title":"Relationship of Exclusive Breastfeeding with The Incidence of Acute Respiratory Infections in Toddlers at The Ringinarum Health Center Kendal Regency","authors":"Izza Alya Ardana Putri, Astin Prima Sari, Ika Dyah Kurniati","doi":"10.26714/magnamed.10.1.2023.60-66","DOIUrl":"https://doi.org/10.26714/magnamed.10.1.2023.60-66","url":null,"abstract":"Background: Acute Respiratory Infection (ARI) is an acute infection affecting the nose, paranasal sinuses, pharynx, trachea, bronchi, lungs, and epiglottis. ARI is the main cause of mortality and morbidity in toddlers in the world. The incidence of ARI can be prevented by exclusive breastfeeding.Objective: To prove the correlation of exclusive breastfeeding with the incidence of ARI in toddlersMethods: This case-control study conducted on December 2021 at the Ringinarum Health Center Kendal Regency. Sampling was conducted by purposive sampling method and was conducted based on inclusion and exclusion criterias.Results: The total samples obtained in this study were 124 samples. This study showed that the characteristics of toddlers with ARI among others the most frequent age is 24-35 months (30,6%), most of them were male (61,3%) and weren’t exclusively breastfed (69,4%). Futhermore, this study also found that there was a correlation between exclusivity of breastfeeding and the incidence of ARI in toddlers (p<0,05). Toddlers who weren’t exclusively breastfed had 5,5 times greater risk of ARI than those who were exclusively breastfed (OR>1).Conclusion: There is a correlation between exclusive breastfeeding with the incidence of acute respiratory infections in toddlers.","PeriodicalId":497782,"journal":{"name":"Magna Medica","volume":"221 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135202000","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Sedentary Lifestyle Phenomenon and Obesity Risk on Students at School and College during Transitions from Conventional School to Online School","authors":"Diana Putri Wibowo, Kartika Prahasanti, M. Reza Utama, Aprilia Paramitasari, Absa Secka","doi":"10.26714/magnamed.10.1.2023.93-108","DOIUrl":"https://doi.org/10.26714/magnamed.10.1.2023.93-108","url":null,"abstract":"Background: Online School was actively carried out during the COVID-19 pandemic in order to reduce social interaction, minimize outdoor activities, and decreasing airborne virus transmission. This activities mainly uses virtual media. During activities, students are advised and ordered to stay inside their house, which causes reduction towards physical activities. Said actions, causes a significant change in their lifestyle and can increase the risk of obesity.Objective: To find out the phenomenon of obesity in conventional education school students, from elementary to high school, during the transition from face-to-face learning to long distance learning.Methods: Reviewing several published scientific articles regarding the phenomenon of increased risk of obesity due to online school during the COVID-19 Pandemic.Results: There is a relationship between online school that increased risk of obesity where are sedentary behavior, stress, and diet. This is because online school makes decreased physical activity, increased screen time, irregular sleep patterns, and stress. This can be experienced by any students.Conclusion: Online learning during the COVID-19 pandemic is proven to escalate risks in students becoming obese, according to an additional increase in their sedentary lifestyle. Hence a modification in their lifestyle and routine is highly needed.","PeriodicalId":497782,"journal":{"name":"Magna Medica","volume":"21 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135202006","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Magna MedicaPub Date : 2023-02-01DOI: 10.26714/magnamed.10.1.2023.40-47
Erwin Rosadi, Lia Yulia Budiarti, Bhisma Ridho Romadhon, Nida Nurkhalishah, Nur Salsabila Apriliani Risma Putri, Nur Azmina Aisyah, Isnaini Isnaini
{"title":"Diabetic Wound Healing Activity of Anabas testudineus Fish Scales","authors":"Erwin Rosadi, Lia Yulia Budiarti, Bhisma Ridho Romadhon, Nida Nurkhalishah, Nur Salsabila Apriliani Risma Putri, Nur Azmina Aisyah, Isnaini Isnaini","doi":"10.26714/magnamed.10.1.2023.40-47","DOIUrl":"https://doi.org/10.26714/magnamed.10.1.2023.40-47","url":null,"abstract":"Background: Anabas testudineus fish scales are part of the fish that has not been used optimally. Fish scales contain chitin. Chitin which undergoes deacetylation, produces chitosan. Chitosan is an efficacious compound for antibacterial and diabetic wound healing.Objective: This study aimed to extract chitosan from fish scales and test the diabetic wound healing activity of fish scale extract gelMethods: Extraction of fish scales using 0.3 M NaOH, 0.55 M HCl, and 50% NaOH. FTIR will analyze the extraction results to see the functional groups of the extract. Activity test of fish scale extracts diabetic wound healing gel was carried out on Rattus novergicus Wistar strain for 14 days. There were five treatments: negative control, positive control given octenillinR, and fish scale extract gel conc. 5%, 10%, and 15%.Results: The results showed that the fish scales extract contained chitosan, and gel extract fish scale conc 5% have diabetic wound healing activity better than 10% and 15%. Conclusion: A. testudineus fish scale extract contains chitosan, as seen from the FTIR results.","PeriodicalId":497782,"journal":{"name":"Magna Medica","volume":"15 9","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135202001","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}