{"title":"Herbal - Synthetic Drug Interactions","authors":"Kintoko Kintoko, Aghnia Nabila Ananda, Anisa Rifka Ridho, Annisa Camellia Makati, Asti Afrida Yanti, Dina Wahyuni, Yolanda Sajjida Maghfirah, Isnaini Isnaini","doi":"10.26714/magnamed.10.2.2023.211-220","DOIUrl":"https://doi.org/10.26714/magnamed.10.2.2023.211-220","url":null,"abstract":"Background: Herbal medicine is currently one of the therapeutic options chosen by the community because it is considered relatively safer and has minimal side effects. Not only used as a single drug, but herbal ingredients can also be combined with synthetic drugs. However, using herbal and synthetic drugs simultaneously can cause a variety of interactions, including synergism, antagonism, and additive effects (potentiation).Objective: Therefore, it is crucial to do a literature study on the reaction of various herbal medicines to unwanted synthetic drugs to prevent the adverse effects that can be caused.Methods: The literature review is processed based on academic journals published on NCBI, PubMed, and online journal sources that discuss the interactions between herbal medicines and synthetic drugs from 1997 to 2022.Results: Herbal drug interactions can be avoided or managed by providing correct patient advice based on reliable information.Conclusion:The main basic principles of administering these medicines include the doctor's full awareness of the effects and interactions between herbal medicines and herbal medicines and herbal medicines with synthetic drugs.","PeriodicalId":497782,"journal":{"name":"Magna Medica","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135310309","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Magna MedicaPub Date : 2023-08-13DOI: 10.26714/magnamed.10.2.2023.252-257
Lilik Lestari, Muhammad Harris Sis Sultansyah
{"title":"Teratomas Mediastinal Recurrent with Massive Pericardial Effusion","authors":"Lilik Lestari, Muhammad Harris Sis Sultansyah","doi":"10.26714/magnamed.10.2.2023.252-257","DOIUrl":"https://doi.org/10.26714/magnamed.10.2.2023.252-257","url":null,"abstract":"Background: Mediastinal teratoma is a medical rare disease that refers to the presence of a regrowing teratoma tumor in the mediastinum. At the pulmonary hospital dr. Ario Wirawan Salatiga, only one case was found, where the patient had previously been operated on at another hospital.Objective: The purpose of this paper was to contribute to the radiology literature by presenting a case of recurrent teratoma.Case Presentation: A 19-year-old male patient complained of persistent shortness of breath. The patient previously underwent teratoma surgery. The patient underwent chest X-rays, CT scans, abdominal and cardiac ultrasounds (USG), and as well as biopsies. The results of the CT scan found a teratoma-type mediastinal tumor accompanied by a large amount of pericardial effusion. A hyperechoic lesion with well-defined borders, round-oval, lobulated, and very large in size. Location in the mediastinum that is urgent and involves the left ventricle, right ventricle, left atrium, and right atrium. There is also an aortic compression lesion accompanied by calcification (+). Examination by ultrasonography (USG) of the heart found many pericardial but not found pressing. Heart valve function in patients did not show any abnormalities.Conclusion: Recurrent teratomas with large-volume pericardial effusions are rare. In this case study, a teratoma is located in the mediastinum. In this case, axial, coronal, and sagittal slices of a contrast thoracic CT scan can be used to establish the diagnosis. The results of heart USG found a pericardial effusion, the heart chambers do not collapse in this case of recurrent teratomas, indicating a mature teratoma type.","PeriodicalId":497782,"journal":{"name":"Magna Medica","volume":"36 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135310310","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Dominant Factors of Adherence with Taking Medicine in Elderly Hypertensive Patients","authors":"Herlina Herlina, Retno Mardhiati, Rismawati Pangestika","doi":"10.26714/magnamed.10.2.2023.199-210","DOIUrl":"https://doi.org/10.26714/magnamed.10.2.2023.199-210","url":null,"abstract":"Background: Adherence to taking medication is a prerequisite for hypertension treatment to be more effective and most likely to cure patients in controlling hypertension so that complications and death do not occurObjective: The objective of this study is to discover the dominant factors of elderly hypertension patients' conformity to medication at the Jatinegara District Health CenterMethods: It is a quantitative study with Cross Sectional approach. It involved 200 respondents, as the sample was taken using a quota sampling technique.Results: Univariate results showed that 25% of elderly hypertensive patients did not adhere to medication. In bivariate analysis, it was found that family support, self-efficacy, motivation, and health workers' roles were related (p-value <0.05) to adherence to hypertension medication consumption. Meanwhile, no relation (p-value 0.05) existed between age, knowledge, attitude, access to healthcare facilities, and JKN participation variables. The dominant variable observed from the multivariate result was the interaction of attitudes and self-efficacy (OR: 23,943).Conclusion:Based on multivariate analysis, it was found that the influential factors were self-efficacy and attitudes.","PeriodicalId":497782,"journal":{"name":"Magna Medica","volume":"33 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135310312","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Magna MedicaPub Date : 2023-08-13DOI: 10.26714/magnamed.10.2.2023.221-228
Ahmad Firdaus, Adelita Vega Dwiputri, Aderisti Irkadiratna, Adi Satria Nugraha, Adinda Narulitia, Era Catur Prasetya, Absa Secka, Muhammad Muslih
{"title":"Post-COVID Syndrome in Bipolar Affective Disorder Patient","authors":"Ahmad Firdaus, Adelita Vega Dwiputri, Aderisti Irkadiratna, Adi Satria Nugraha, Adinda Narulitia, Era Catur Prasetya, Absa Secka, Muhammad Muslih","doi":"10.26714/magnamed.10.2.2023.221-228","DOIUrl":"https://doi.org/10.26714/magnamed.10.2.2023.221-228","url":null,"abstract":"Background: Post-COVID is a multifactorial disease that describes the residual effects of acute COVID-19 infection that are continuous or relapsing and in remission. The study found that 87% of people who recovered and were discharged from the hospital showed persistence of at least one symptom even within 60 days. COVID-19 patients who have bipolar disorder require therapeutic adjustments to avoid specific drug interactions between psychotropic drugs and those used in COVID-19 protocols. Objective: To determine the treatment of post-COVID patients with bipolar affective disorder.Methods: Collect and analyze research articles on Update Therapy for Post-COVID Syndrome Patients with Bipolar Affective Disorder. These articles were obtained by searching using Google Scholar, PubMed/NCBI, and SAGE Journal. Results: The use of combination drugs between antipsychotics and antidepressants with hydroxychloroquine/azithromycin is not recommended because it has side effects that can induce psychiatric symptoms. COVID-19 patients with bipolar disorder (BD) who do not respond to pharmacotherapy may receive electroconvulsive therapy (ECT). Non-pharmacological therapies such as counseling and the use of telepsychiatry are effective in treating mental health and overcoming adverse psychological effects.Conclusion: COVID-19 patients with bipolar affective disorder require unique therapy to avoid drug interactions and pharma-cotherapy. Non-pharmacological efforts include counseling and telepsychiatry to cope with emotional distress and mental health challenges. However, challenges remain in providing care for these patients.","PeriodicalId":497782,"journal":{"name":"Magna Medica","volume":"10 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135310308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Magna MedicaPub Date : 2023-08-13DOI: 10.26714/magnamed.10.2.2023.229-238
Friska Handayani, Irvan Medison, Dewi Wahyu Fitrina, Dessy Mizarti
{"title":"Pleural Amebiasis without Hepar Involvement","authors":"Friska Handayani, Irvan Medison, Dewi Wahyu Fitrina, Dessy Mizarti","doi":"10.26714/magnamed.10.2.2023.229-238","DOIUrl":"https://doi.org/10.26714/magnamed.10.2.2023.229-238","url":null,"abstract":"Background: Pleuropulmonary amebiasis is the most common complication of amoebic liver abscess, occurring in 15% of patients with amoebic liver disease and in 1% of patients with amoebic dysentery. Most commonly occurs by direct extension of a right superior lobe hepatic abscess through the diaphragm to the right lower lobe of the lung with a mortality rate of 5-16%. Primary pleural amebiasis without liver involvement is rare.Case Presentation: Reported an 18-year-old male patient with pleural amebiasis from the results of parasitological examination of pleural fluid found Entamoeba histolytica. History, physical examination and support showed normal liver function. The patient has a history of poor sanitation with a dissertation of unhygienic habits. Patients without liver problems remain at risk for amoebiasis pleuraConclusion: Pleural amebiasis without liver involvement was a rare case. Further investigation was needed in patients with pleural amoebiasis to other organs, such as the liver and digestive tract. Diagnose pleural amebiasis should be the main focus in determining the etiology. Entamoeba histolytica may be involved in pleural inflammation and cause effusion.","PeriodicalId":497782,"journal":{"name":"Magna Medica","volume":"67 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135310313","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Magna MedicaPub Date : 2023-08-13DOI: 10.26714/magnamed.10.2.2023.239-251
Rijanto Agoeng Basoeki, Alyaa Nabiila, Adinda Narulitia, Yoga Eko Saputra, Trimayanti Olfah, Eko Nursucahyo, Muhammad Anas
{"title":"Germ Cell Tumors Ovary “Dysgerminoma” with Mayer-Rokitansky-Kuster-Hauser Syndrome","authors":"Rijanto Agoeng Basoeki, Alyaa Nabiila, Adinda Narulitia, Yoga Eko Saputra, Trimayanti Olfah, Eko Nursucahyo, Muhammad Anas","doi":"10.26714/magnamed.10.2.2023.239-251","DOIUrl":"https://doi.org/10.26714/magnamed.10.2.2023.239-251","url":null,"abstract":"Background: Ovarian Germ Cell Tumors originate from primitive germinal cells and can be either malignant or benign. MRKH syndrome is characterized by congenital hypoplasia of the uterus and upper vagina and can occur due to disrupted fusion of the Mullerian ducts. Diagnosis of ovarian tumors in MRKH patients is difficult but can be characterized by abdominal pain and distended.Objective: The aim of this case report is to explain the diagnostic methods and interventions performed in patients with ovarian tumors and MRKH syndrome.Case Presentation: A 25-year-old female came to the hospital with complaints of a lower abdominal lump three months ago. It was followed by severe pain, weight loss, shortness of breath, and yellowish vaginal discharge. Physical examination showed anemia, obesity, and a vagina size of 7cm with a probe. Chest X-ray showed a mass in the mediastinum and pleural effusion, and USG showed suspicion of an ovarian cyst and uterine agenesis.Conclusion: Ovarian tumor with MRKH syndrome is a rare case. Diagnosis was based on the patient’s history, clinical findings, radiologic examination, and confirmed with laparotomy and histopathology. Regular examinations are recommended to prevent and identify genital tract problems and pelvic diseases in women, especially adolescents.","PeriodicalId":497782,"journal":{"name":"Magna Medica","volume":"189 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135310311","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Mental Health Status Among UNIMAS Medical Students During the Pandemic Covid-19","authors":"Norhida Ramli, Foong Zhimin, Maziah Fathiah Mohammed, Aizuddin Zhafri Rasid, Nurodarina Othman, Shazrina Ahmad Razali","doi":"10.26714/magnamed.10.2.2023.179-190","DOIUrl":"https://doi.org/10.26714/magnamed.10.2.2023.179-190","url":null,"abstract":"Background: Due to the outbreak of Covid-19, medical students were suffering from poor mental health, leading to depression, anxiety, and stress. Research to better understand mental health is essential because of the high prevalence of poor mental health among students during the pandemic.Objective: Therefore, the study aims to determine the mental health status of UNIMAS medical students during the Covid-19 pandemic. In this study, the predictive validity of the Depression, Anxiety, and Stress Scale (DASS-21) for the presence of a depressive disorder and its associated coping factors were investigated among medical students.Methods: A cross-sectional study was conducted among medical students from the University Malaysia Sarawak's Faculty of Medicine and Health Sciences. The DASS-21 was administered to 411 respondents, and data were analyzed using Man-Whitney and Chi-Square tests.Results: The result showed that most medical students had normal levels of depression (75.7%), anxiety (74.2%), and stress (92.5%). The highest coping method used was rest and sleep (95.1%), followed by singing and listening to music (91.5%).Conclusion: Most UNIMAS medical students were in good mental health during the COVID-19 pandemic. They tend to have a better-coping mechanism before the stressful condition deteriorates.","PeriodicalId":497782,"journal":{"name":"Magna Medica","volume":"32 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135598375","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Relationship of Smoking Status and Severity of Inpatient Community Acquired Pneumonia (CAP)","authors":"Risa Septia Karisma, Sahrun Sahrun, Ronanarasafa Ronanarasafa, Risky Irawan Putra Priono","doi":"10.26714/magnamed.10.2.2023.150-162","DOIUrl":"https://doi.org/10.26714/magnamed.10.2.2023.150-162","url":null,"abstract":"Background: Pneumonia is an inflammation of the lung parenchyma. Pneumonia became the first most lung health problem in West Lombok. Smoking is one of the main factors in CAP. This study aims to determine the relationship between smoking status and severity of inpatient CAP patients.Methods: Case control study design was used with medical record measurement tools. A total of 70 samples were taken using a purposive sampling technique for community pneumonia patients (CAP) at Patut Patuh Patju Regional General Hospital Gerung, West Lombok in November 2021-October 2022. Calculation of the severity of CAP patients used the PSI score. Results: The results obtained a p-value of 0.000 (p-value <0.05) for smoker status with a degree of severity of CAP, and a p-value of 0.064 (p-value> 0.05) for a degree of smoking with a degree of severity of CAP. The estimated risk (OR) for smoking status with the severity of CAP is 19.33.Conclusions: There is a significant relationship between smoking status, but not with smoking degree, to severity of CAP at Patut Patuh Patju Gerung Regional General Hospital, West Lombok.","PeriodicalId":497782,"journal":{"name":"Magna Medica","volume":"198 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136045394","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Magna MedicaPub Date : 2023-08-06DOI: 10.26714/magnamed.10.2.2023.170-178
Supriyatiningsih Wenang, Muhammad Kurniawan, Nicko Rachmanio
{"title":"Knowledge about Nutrition and Testing Gestational Hypertension in Multiple Pregnancies","authors":"Supriyatiningsih Wenang, Muhammad Kurniawan, Nicko Rachmanio","doi":"10.26714/magnamed.10.2.2023.170-178","DOIUrl":"https://doi.org/10.26714/magnamed.10.2.2023.170-178","url":null,"abstract":"Background: Hypertensive disorders in pregnancy (HDP) are a leading contributor to maternal, fetal, and newborn death all over the world, including in Indonesia. Routine pregnancy check-ups and nutritional status can prevent pregnancy complications due to HDP.Objective: To increase health workers’ knowledge about the importance of blood pressure check-ups and adequate nutrition during multiple pregnancies.Methods: The PKM material was delivered through online seminars with 20 employees and their families at Asri Medical Center Hospital. The material provided included knowledge about women's health, multiple pregnancies, nutrition for pregnant women, as well as hypertension in pregnancy, and their management. Pretest and posttest was conducted. The analysis method used Wilcoxon Signed Rank test.Results: The analysis showed a 25% increase in knowledge from the results of the pretest of 75% to a total of 100% at the time of the posttest (p < 0.05), which suggests that there is a difference in the respondents’ knowledge levels about the importance of nutrition and examination of hypertension in multiple pregnancies.Conclusion: There is a significant difference in knowledge about the importance of nutrition and examination of hypertension in multiple pregnancies before and after the seminar at AMC Muhammadiyah Hospital.","PeriodicalId":497782,"journal":{"name":"Magna Medica","volume":"4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136045391","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comparison of Pericanalicular and Intracanalicular Fibroadenoma Mammae Growth Pattern on Various Age Range","authors":"Hilda Maulyda Utamie, Ira Citra Ningrom, Yuhantoro Budi Handoyo Sakti, Andi Muh. Maulana","doi":"10.26714/magnamed.10.2.2023.191-198","DOIUrl":"https://doi.org/10.26714/magnamed.10.2.2023.191-198","url":null,"abstract":"Background: Fibroadenoma mammae is the most common type of benign breast tumor in women. Fibroadenoma mammae can occur on various ages, there is no much data recorded about anatomical pathology especially regarding the distribution of fibroadenoma mammae growth pattern in Siaga Medika Purbalingga Hospital. Study in Indonesia that focus on this topic also remain scarce.Objective: To analyze comparison between the growth pattern in fibroadenoma mammae patients with age range 11-50 years.Method: This cross-sectional study with data collected restrospectively based on medical records and histopatological examination in Siaga Medika Purbalingga Hospital. Statistical analysis was done using JASP 0.14.1.0.Results: The majority of patients with fibroadenoma mammae were in the age range 21-30 years (48.9%) with pericanalicular pattern (66%). The four groups had different two growth pattern (p <0.001). Odds ratio showed 3.4 that means patient with age ≤30 years has chance 3.4x to diagnose with pericanalicular fibroadenoma mammae than patient with age >30 years.Conclusion: Incidence of pericanalicular and intracanalicular fibroadenoma mammae growth pattern in Siaga Medika Purbalingga Hospital patients can be affected by age.","PeriodicalId":497782,"journal":{"name":"Magna Medica","volume":"7 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136045395","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}