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Autobiographical hypermnesia as a particular form of mental time travel. 自传式失忆症是一种特殊形式的精神时间旅行。
IF 0.8 4区 医学
Neurocase Pub Date : 2025-08-01 DOI: 10.1080/13554794.2025.2537950
Valentina La Corte, Pascale Piolino, Laurent Cohen
{"title":"Autobiographical hypermnesia as a particular form of mental time travel.","authors":"Valentina La Corte, Pascale Piolino, Laurent Cohen","doi":"10.1080/13554794.2025.2537950","DOIUrl":"10.1080/13554794.2025.2537950","url":null,"abstract":"<p><p><i>Hyperthymesia</i> has been described in individuals, who show superior retrieval capacities in autobiographical memory. This condition differs from superior memory, which refers to the supranormal ability to acquire and recall new information but not autobiographical information. The process responsible for hyperthymesia is still largely unknown and most knowledge come from case studies, showing individual with impressive superior capacities to retrieve autobiographical memories. Here, we describe a case of hyperthymesia with an objective as well as a subjective assessment of mental time travel abilities in different temporal distances. This is the first observation of hyperthymesia with a full evaluation of mental time travel capacities in different temporal distances, encompassing the individual capacity to retrieve personal events from the personal past as well as to foresee personal events in the future. This observation could pave the way to further research on superior autobiographical abilities, studied in the context of personal temporality.</p>","PeriodicalId":49762,"journal":{"name":"Neurocase","volume":" ","pages":"188-192"},"PeriodicalIF":0.8,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144762112","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Inner dialogue dysfunction and the abusive comments of the dominant hemisphere. 内部对话功能障碍和主导半球的辱骂性评论。
IF 0.8 4区 医学
Neurocase Pub Date : 2025-08-01 Epub Date: 2024-12-19 DOI: 10.1080/13554794.2024.2442010
Luis Fornazzari, Mila Valcic, Matthew Juhasz, Corinne E Fischer
{"title":"Inner dialogue dysfunction and the abusive comments of the dominant hemisphere.","authors":"Luis Fornazzari, Mila Valcic, Matthew Juhasz, Corinne E Fischer","doi":"10.1080/13554794.2024.2442010","DOIUrl":"10.1080/13554794.2024.2442010","url":null,"abstract":"<p><p>Inner dialogue and inner speech are normal systems of cerebral intrapersonal communication, crucial to self-awareness. Lesions affecting the cerebral network involved in these systems have been associated with the occurrence of Auditory Verbal Hallucinations (AVHs). These are regarde as a continuum phenomenon experienced by healthy, individuals, as well as those with psychiatric disorders. In this paper, two patients with left hemispheric lesions of different pathologies, vascular and tumor, respectively, who during their recovery of motor and sensory functions presented severe deregulation in their inner dialogue. In both cases, the damaged left dominant hemisphere adopted arrogant, demeaning, and abusive inner speech, while the right non-dominant side, which commands the rehabilitation of the lost functions, was subdued and quiet. This abusive unilateral inner dialogue was present until adequate recovery of independent functions was achieved for both patients.</p>","PeriodicalId":49762,"journal":{"name":"Neurocase","volume":" ","pages":"101-107"},"PeriodicalIF":0.8,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142856363","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The digitalization of psychopathology: 'TV sign' and 'Smartphone sign' as red flags for dementia. 精神病理学的数字化：“电视信号”和“智能手机信号”是痴呆症的危险信号。
IF 0.8 4区 医学
Neurocase Pub Date : 2025-08-01 Epub Date: 2025-02-21 DOI: 10.1080/13554794.2025.2467925
Porimita Chutia, Shailendra Mohan Tripathi, Ashwin Jv
{"title":"The digitalization of psychopathology: 'TV sign' and 'Smartphone sign' as red flags for dementia.","authors":"Porimita Chutia, Shailendra Mohan Tripathi, Ashwin Jv","doi":"10.1080/13554794.2025.2467925","DOIUrl":"10.1080/13554794.2025.2467925","url":null,"abstract":"<p><p>This case series elucidates pathological signs for diagnosis in two patients with Dementia. The first case highlights the term 'Smartphone sign', a novel psychopathology uncovered based on the existing 'TV sign', a rare type of delusional misidentification syndrome (DMS). The second case had symptoms consistent with the 'TV sign'. The possible underlying cause of these signs was hypothesized based on psychopathology, brain region, sensory system, cognition, and environmental factors. Moreover, the treatment outcome in terms of cognition and behavior on low doses of Risperidone and Escitalopram shows promising results and paves the way for the treatment of other DMS.</p>","PeriodicalId":49762,"journal":{"name":"Neurocase","volume":" ","pages":"119-123"},"PeriodicalIF":0.8,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143469792","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Amusia representing impairment of absolute pitch perception due to damage to the middle longitudinal fasciculus: a case report. 失音症表现绝对音高知觉因中纵束损伤而受损：1例报告。
IF 0.8 4区 医学
Neurocase Pub Date : 2025-08-01 Epub Date: 2025-07-22 DOI: 10.1080/13554794.2025.2531804
Masayuki Satoh
{"title":"Amusia representing impairment of absolute pitch perception due to damage to the middle longitudinal fasciculus: a case report.","authors":"Masayuki Satoh","doi":"10.1080/13554794.2025.2531804","DOIUrl":"10.1080/13554794.2025.2531804","url":null,"abstract":"<p><p>Absolute pitch (AP) is the ability to identify the pitch of isolated tones without reference to an external pitch. A 21-year-old semi-professional musician with a previous ability for AP developed a left-hemispheric cerebral hemorrhage due to an arteriovenous malformation (AVM). One month after the hemorrhage, she underwent surgery to treat the AVM, resulting in the resolution of her aphasia and right upper limb clumsiness. However, her AP ability was lost. Before the hemorrhage, she could dictate complex music that she listened to, but afterward, she could no longer identify even a single tone. Neuropsychological assessments revealed a decreased retention span for auditory information, slight impairment of environmental sound and speech processing, and difficulty in understanding the auditory presentation of numbers with more than four digits. Neuromusicological assessments with an established battery of tests revealed impairments of chord and timbre perception, alongside the loss of AP ability. Brain computed tomography conducted 9 months after the hemorrhage revealed low-density areas in the middle longitudinal fasciculus, a region associated with language and auditory processing, including AP perception. To our knowledge, this is the first reported case of a patient with AP loss because of a focal brain lesion.</p>","PeriodicalId":49762,"journal":{"name":"Neurocase","volume":" ","pages":"155-166"},"PeriodicalIF":0.8,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144692210","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mills syndrome as a rare and significant motor neuron disease: a case report. 米尔斯综合征是一种罕见而重要的运动神经元疾病：1例报告。
IF 0.8 4区 医学
Neurocase Pub Date : 2025-08-01 Epub Date: 2025-04-11 DOI: 10.1080/13554794.2025.2489930
Ozlem Onder, Sahin Isik
{"title":"Mills syndrome as a rare and significant motor neuron disease: a case report.","authors":"Ozlem Onder, Sahin Isik","doi":"10.1080/13554794.2025.2489930","DOIUrl":"10.1080/13554794.2025.2489930","url":null,"abstract":"<p><p>Mills' syndrome is a rare motor neuron disease characterized by progressive upper motor neuron dysfunction. As the disease advances, there may be manifestations of bulbar involvement, such as dysarthria, dysphagia, and possibly pseudobulbar affect and progression to the contralateral side may occur lately in patients. Since it was first described by Mills in 1900, there are few cases of Mills' syndrome that have been reported in the literature. Here, we present a case, diagnosed as Mills' syndrome, with 5 years of gradually progressive weakness and stiffness in her left-side limbs with recently added difficulties in speech. Neurological examination revealed bilateral asymmetrical upper motor neuron signs, including increased tone, brisk reflexes, and muscle weakness with dysarthria and dysphagia. There was no sensory involvement as well as sphincter dysfunction and her cognition was contact.</p>","PeriodicalId":49762,"journal":{"name":"Neurocase","volume":" ","pages":"143-148"},"PeriodicalIF":0.8,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144003462","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Relationship between Emotional Expression, Difficulty in Emotion Regulation and Anhedonia in Parkinson's Disease. 帕金森病患者情绪表达、情绪调节困难与快感缺乏的关系
IF 0.8 4区 医学
Neurocase Pub Date : 2025-08-01 Epub Date: 2025-02-20 DOI: 10.1080/13554794.2025.2467910
Fatma Gül Helvaci Çelik, Yunus Emre Aktaş, Seda Kiraz, Demet Şeker, Çiçek Hocaoğlu
{"title":"The Relationship between Emotional Expression, Difficulty in Emotion Regulation and Anhedonia in Parkinson's Disease.","authors":"Fatma Gül Helvaci Çelik, Yunus Emre Aktaş, Seda Kiraz, Demet Şeker, Çiçek Hocaoğlu","doi":"10.1080/13554794.2025.2467910","DOIUrl":"10.1080/13554794.2025.2467910","url":null,"abstract":"<p><p>Parkinson's disease (PD), a range of neuropsychiatric symptoms, including anhedonia, depression, emotional control, and cognitive deficits, may manifest. This study aims to investigate the impact of anhedonia, emotional regulation, and emotional expression on PD. The research included 68 PD patients and 60 healthy controls. Both groups were assessed using the Hospital Anxiety and Depression Scale (HADS), Emotional Expression Scale (EES), the Short Form of the Difficulties in Emotion Regulation Scale (DERS), and the Clinician-Administered Snaith-Hamilton Pleasure Scale (SHAPS), all administered by a psychiatrist. The PD group was evaluated by a neurology specialist using the Unified Parkinson's Disease Rating Scale (UPDRS). Results showed that the PD group scored significantly higher on the HADS (<i>p</i> < 0.01), DERS (<i>p</i> < 0.01), and SHAPS (<i>p</i> < 0.01), while their EES scores were significantly lower (<i>p</i> < 0.01) compared to the control group. Further analysis indicated that a one-unit increase in anhedonia scores corresponded to a 3.125 unit rise in non-motor symptom scores and a 5.034 unit rise in motor symptom scores. The findings suggest that anhedonia is a strong predictor of both motor and non-motor symptoms in PD. The data indicate that the link between anhedonia and PD exists independently of depression and anxiety, highlighting the necessity of addressing anhedonia as a distinct symptom in PD.</p>","PeriodicalId":49762,"journal":{"name":"Neurocase","volume":" ","pages":"112-118"},"PeriodicalIF":0.8,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143469794","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Predominant right temporal and frontal brain atrophy and progressive behavioral dementia. A case of prion gene mutation (PRNP). 主要是右侧颞叶和额叶脑萎缩和进行性行为痴呆。朊病毒基因突变1例。
IF 0.8 4区 医学
Neurocase Pub Date : 2025-08-01 Epub Date: 2025-04-12 DOI: 10.1080/13554794.2025.2491746
Evangelos Koumasopoulos, Evangelia Stanitsa, Efthalia Angelopoulou, Christos Koros, Vasiliki Barbarousi, Georgios Velonakis, Athanasios Koulouris, Chrysoula Michaletou, Savvas Konstantinos Alevetsovitis, Vasilios C Constantinides, Andreas Kyrozis, Leonidas Stefanis, Christos Kroupis, Sokratis G Papageorgiou
{"title":"Predominant right temporal and frontal brain atrophy and progressive behavioral dementia. A case of prion gene mutation (PRNP).","authors":"Evangelos Koumasopoulos, Evangelia Stanitsa, Efthalia Angelopoulou, Christos Koros, Vasiliki Barbarousi, Georgios Velonakis, Athanasios Koulouris, Chrysoula Michaletou, Savvas Konstantinos Alevetsovitis, Vasilios C Constantinides, Andreas Kyrozis, Leonidas Stefanis, Christos Kroupis, Sokratis G Papageorgiou","doi":"10.1080/13554794.2025.2491746","DOIUrl":"10.1080/13554794.2025.2491746","url":null,"abstract":"<p><strong>Introduction: </strong>Frontotemporal dementia (FTD) is a rare and often hereditary type of dementia, usually developing under the age of 65 years. Mutations in the gene encoding the prion protein (<i>PRNP</i>), typically resulting in Creutzfeldt-Jakob disease, are an extremely rare cause of FTD phenotype. The clinical spectrum of this genetic form of FTD has not been fully elucidated, and no case carrying a PRNP gene mutation has been previously described in the Greek population.</p><p><strong>Case report: </strong>This case report describes a patient with phenotype of probable behavioral variant frontotemporal dementia (bvFTD) with positive family history of dementia.A mutation in the prion gene (PRNP) is identified as the genetic cause of the behavioral FTD phenotype of the patient.</p><p><strong>Conclusion: </strong>Heterozygous c.623G>A (p.Arg208His) genotype may be responsible for FTD phenotype. This case shows the necessity of genetic testing for possible mutations in the prion gene in patients with bvFTD and positive family history of dementia.</p>","PeriodicalId":49762,"journal":{"name":"Neurocase","volume":" ","pages":"149-154"},"PeriodicalIF":0.8,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144051793","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Heterozygous p62/SQSTM1 mutation and right temporal variant of frontotemporal dementia: Α case report. 额颞叶痴呆p62/SQSTM1杂合突变与右侧颞叶变异：Α病例报告。
IF 0.8 4区 医学
Neurocase Pub Date : 2025-04-01 Epub Date: 2024-12-24 DOI: 10.1080/13554794.2024.2446315
Evangelos Koumasopoulos, Evangelia Stanitsa, Efthalia Angelopoulou, Christos Koros, Vasiliki Barbarousi, Georgios Velonakis, Chrysoula Michaletou, Savvas Konstantinos Alevetsovitis, Vasilios C Constantinides, Andreas Kyrozis, Leonidas Stefanis, Christos Kroupis, Sokratis G Papageorgiou
{"title":"Heterozygous p62/SQSTM1 mutation and right temporal variant of frontotemporal dementia: Α case report.","authors":"Evangelos Koumasopoulos, Evangelia Stanitsa, Efthalia Angelopoulou, Christos Koros, Vasiliki Barbarousi, Georgios Velonakis, Chrysoula Michaletou, Savvas Konstantinos Alevetsovitis, Vasilios C Constantinides, Andreas Kyrozis, Leonidas Stefanis, Christos Kroupis, Sokratis G Papageorgiou","doi":"10.1080/13554794.2024.2446315","DOIUrl":"10.1080/13554794.2024.2446315","url":null,"abstract":"<p><p>Mutations in sequestosome 1 (SQSTM1) gene have been associated with frontotemporal dementia (FTD), amyotrophic lateral sclerosis (ALS), frontotemporal dementia - ALS (FTD-ALS), and very recently, progressive supranuclear palsy (PSP), paget disease of bone (PDB), distal myopathy with rimmed vacuoles (DMRV), and neurodegenerative disorders in childhood. We present a case of right temporal variant of FTD (rtvFTD) with heterozygous mutation (c.823_824del(p.Ser275Phefs *17)) in SQSTM1 gene.</p>","PeriodicalId":49762,"journal":{"name":"Neurocase","volume":" ","pages":"70-73"},"PeriodicalIF":0.8,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142886375","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Correction. 更正。
IF 0.8 4区 医学
Neurocase Pub Date : 2025-04-01 Epub Date: 2024-12-13 DOI: 10.1080/13554794.2024.2442138
{"title":"Correction.","authors":"","doi":"10.1080/13554794.2024.2442138","DOIUrl":"10.1080/13554794.2024.2442138","url":null,"abstract":"","PeriodicalId":49762,"journal":{"name":"Neurocase","volume":" ","pages":"100"},"PeriodicalIF":0.8,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142819818","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Unforeseen hazards: cranial penetration with a metallic chopstick in a suicide attempt. 不可预见的危险：企图自杀时被金属筷子刺穿颅骨。
IF 0.8 4区 医学
Neurocase Pub Date : 2025-04-01 Epub Date: 2024-12-18 DOI: 10.1080/13554794.2024.2443995
Chia-Lo Wu, Yao-Chung Yang, Yu-Hone Hsu
{"title":"Unforeseen hazards: cranial penetration with a metallic chopstick in a suicide attempt.","authors":"Chia-Lo Wu, Yao-Chung Yang, Yu-Hone Hsu","doi":"10.1080/13554794.2024.2443995","DOIUrl":"10.1080/13554794.2024.2443995","url":null,"abstract":"<p><p>A 71-year-old man attempted suicide by self-inflicting a cranial injury with a metallic chopstick following a family dispute. CT imaging showed penetration through the frontal sinus and lobe, yet the patient experienced no significant neurological deficits. Mini-craniotomy revealed a dural deficit without active bleeding. The favorable outcome is attributed to anatomical factors and the chopstick's limited penetrative ability. Successful recovery was achieved through minimal debridement and appropriate antibiotic therapy. This case highlights both the dangers of common objects and the importance of precise preoperative imaging and conservative surgical approaches in traumatic brain injuries.</p>","PeriodicalId":49762,"journal":{"name":"Neurocase","volume":" ","pages":"92-95"},"PeriodicalIF":0.8,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142856366","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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