Neurology Asia最新文献_第6页

Partial Onyx embolization triggers spontaneous regression of cerebral AVM: A case report 部分玛瑙栓塞引发脑AVM自发性消退1例

4区医学

Neurology Asia Pub Date : 2023-09-01 DOI: 10.54029/2023xkw

Yihui Ma, Zejin Li, Tingbao Zhang, Yu Feng, Wenyuan Zhao

引用次数: 0

4区医学

Neurology Asia Pub Date : 2023-09-01 DOI: 10.54029/2023scy

Hande Tekin, Pınar Edem

{"title":"CAV-3-related age-dependent muscle diseases: A novel mutation in mother and son","authors":"Hande Tekin, Pınar Edem","doi":"10.54029/2023scy","DOIUrl":"https://doi.org/10.54029/2023scy","url":null,"abstract":"The caveolin-3 protein encoded by the CAV-3 gene is a muscle-specific protein found in skeletal, smooth, and cardiac muscle. Caveolin-3 defects lead to several muscle diseases: rippling muscle disease (RMD), limb-girdle muscular dystrophy (LGMD1C), distal myopathy, familial hypertrophic cardiomyopathy, and asymptomatic hyper-CK-emia. While some variants that cause mutations in this gene cause a pure type of disease, some variants may appear as overlap syndromes. Even in the same variants of CAV-3 mutation, the type of muscle disease, its severity, and time of occurrence can be variable. For this reason, it should be known that CAV-3-related diseases and all overlapping diseases can be seen over time, and the patient should be followed up. We report here a 9-year- old boy and his 38-year-old mother who were investigated for asymptomatic hyper-CK-emia and diagnosed with caveolinopathy. The boy had calf hypertrophy and percussion-induced rapid muscle contraction (PIRCs). His mother had calf hypertrophy, contractions due to percussion, and proximal muscle weakness. Mother’s proximal muscles and m. gastrocnemius magnetic resonance imaging (MRI) was normal. The mother had complaints of weakness, showing slow progression starting from the second decade. Heterozygous (ENST000003cav3849.2) c.298A>T p.Ile100Phe variant in exon 2 was detected in the CAV-3 gene. This mutation is classified as pathogenic according to The American College of Medical Genetics and Genomics (ACMG) criteria (PM1, PM2, PP3, PM5). In conclusion, calves’ pseudohypertrophy and mildly raised CK without weakness can be the initial presentation of caveolinopathy. Percussion-induced muscle contractions, rather than muscle rippling, can occur at a young age. The onset of muscle weakness can be delayed during adolescence and can have a slowly deteriorating course associated with myalgia.","PeriodicalId":49757,"journal":{"name":"Neurology Asia","volume":"17 4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135638085","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The effect of discharge training and telephone counseling service on patients’ functional status and caregiver burden after stroke: A randomized controlled trial 出院培训和电话咨询服务对脑卒中患者功能状态和照顾者负担的影响:一项随机对照试验

4区医学

Neurology Asia Pub Date : 2023-09-01 DOI: 10.54029/2023xmx

Deniz Ezgi BİTEK, Özgül EROL

{"title":"The effect of discharge training and telephone counseling service on patients’ functional status and caregiver burden after stroke: A randomized controlled trial","authors":"Deniz Ezgi BİTEK, Özgül EROL","doi":"10.54029/2023xmx","DOIUrl":"https://doi.org/10.54029/2023xmx","url":null,"abstract":"Objective: This study aimed to determine the effect of discharge training and telephone counseling service on patients’ functional status and caregiver burden after stroke. Methods: This study was conducted as a randomized controlled trial in 69 stroke patients and their caregivers. Discharge training and telephone counseling were given to the caregivers in the intervention group. Caregivers also received telephone counseling by calling researcher when needed. Information form for participants, Modified Rankin Scale, Barthel Index and The Zarit Caregiver Burden Scale were used for data collection. Pre-tests were applied to the intervention and control groups before discharge. Three months after discharge post-tests were performed for the two groups. Results: Three months after discharge, caregivers’ burden was significantly lower in the intervention group compared to the control group. The mean Modified Rankin Scale score of the patients in the intervention group was significantly lower than the control group three months after discharge. Although the mean Barthel Index score of the patients in the intervention group was statistically significant higher than before discharge, but the difference between the groups was not statistically significant. Conclusion: Discharge training and telephone counseling provided to the caregivers of stroke patients reduced the caregiver burden and had a positive effect on the improvement of the functional status of the patients.","PeriodicalId":49757,"journal":{"name":"Neurology Asia","volume":"28 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135638086","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Serum galectin-3 as a potential predictive biomarker Is associated with post-stroke depression 血清半乳糖凝集素-3作为潜在的预测性生物标志物与脑卒中后抑郁相关

4区医学

Neurology Asia Pub Date : 2023-09-01 DOI: 10.54029/2023szm

Weiyuan Yuan, YiMeng Feng, Ting Yang, Kedierya Mahemuti, Ensheng Yao

{"title":"Serum galectin-3 as a potential predictive biomarker Is associated with post-stroke depression","authors":"Weiyuan Yuan, YiMeng Feng, Ting Yang, Kedierya Mahemuti, Ensheng Yao","doi":"10.54029/2023szm","DOIUrl":"https://doi.org/10.54029/2023szm","url":null,"abstract":"Objective: As an inflammatory mediator, serum galectin-3 is involved in a variety of biological processes, including fibrosis, angiogenesis, apoptosis and immune activation, as well as in the physiological and pathological processes of multiple nervous system diseases. The aim of this study was to investigate the relationship between serum galectin-3 and post-stroke depression in acute ischemic stroke (AIS) patients. Methods: Baseline data of patients with AIS admitted to the Department of Neurology, First Affiliated Hospital, Shihezi University School of Medicine from October 2021 to May 2022 were continuously collected. The general data of the patients were collected and serum galectin-3 levels were measured. Hamilton Depression Scale was used to evaluate the occurrence of post-stroke depression. Results: The level of serum galectin-3 was increased in AIS patients with post-stroke depression. The prevalence of post-stroke depression increased with the increase of serum galectin-3 level, suggesting that serum galectin-3 was associated with post-stroke depression. The findings from the ROC curve showed that the area under the curve of serum galectin-3 as a possible biomarker for diagnosing post- stroke depression in AIS patients was 0.719. The sensitivity and specificity were 78.1% and 65.2%, respectively. Multivariate logistic regression analysis showed that serum galectin-3 level remained to be a predictor of post-stroke depression. Conclusions: Elevated serum galectin-3 levels are linked to a higher risk of post-stroke depression. Serum galectin-3 may be a promising biomarker for clinical monitoring of post-stroke depression.","PeriodicalId":49757,"journal":{"name":"Neurology Asia","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135637773","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Acupuncture in the treatment of stroke: A bibliometric analysis based on Citespace 针灸治疗脑卒中:基于Citespace的文献计量学分析

4区医学

Neurology Asia Pub Date : 2023-09-01 DOI: 10.54029/2023tie

Yajing Zhang, Yu Shen, Xixi Dang, Xiaomeng Chen, Yirong Yang, Ying Xiong, Daojun Hong

{"title":"Acupuncture in the treatment of stroke: A bibliometric analysis based on Citespace","authors":"Yajing Zhang, Yu Shen, Xixi Dang, Xiaomeng Chen, Yirong Yang, Ying Xiong, Daojun Hong","doi":"10.54029/2023tie","DOIUrl":"https://doi.org/10.54029/2023tie","url":null,"abstract":"Background & Objectives: Stroke is an acute cerebrovascular disease with high morbidity, high mortality and high disability rate. Acupuncture has been widely used in the treatment of stroke. However, bibliometrics on acupuncture for stroke are still lacking. This study aims to analyze the global research trend of acupuncture treatment for stroke in the past 20 years. Methods: A systematic search was conducted in Web of Science about acupuncture in the treatment of stroke. The databases were searched from inception to August 2022. Citespace is a service that researches the underlying knowledge in the scientific literature. We used it to analyze the relationship between publication year and country, institution, journal, author, bibliography, and keywords about acupuncture for stroke. Results: A total of 897 articles were included for analysis. Over the past 20 years, the results showed a steady increase in the number of articles about acupuncture treatment for stroke. The country with the largest number of publications is the People’s Republic of China (670), and the institution with the largest number of publications is Beijing University of Traditional Chinese Medicine (66). Keyword analysis showed that acupuncture in the treatment of post-stroke conscious cognitive impairment is the research development trend and focus on this field. Conclusion: This study provides a visual analysis method for the trends and frontiers of acupuncture treatment for stroke. Acupuncture is the research development trend for the treatment of post-stroke conscious cognitive impairment. Although most studies conclude that acupuncture has a positive effect on stroke, a large sample, randomized controlled trials are still needed to analyze the efficacy and physiological mechanisms of acupuncture in the treatment of stroke.","PeriodicalId":49757,"journal":{"name":"Neurology Asia","volume":"70 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135637774","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Paraneoplastic seropositive AQP4-IgG neuromyelitis optica spectrum disorder associated with sigmoid adenocarcinoma 副肿瘤AQP4-IgG血清阳性视神经脊髓炎频谱障碍伴乙状结肠腺癌

4区医学

Neurology Asia Pub Date : 2023-09-01 DOI: 10.54029/2023kvu

Sarah Hasnor Abu Hassan, Sumit Kumar Sonu

引用次数: 0

Papilledema with acute profound visual loss in capillary haemangioma of the sphenoid sinus with sellar and parasellar extensions – a triple rarity presentation 蝶窦毛细血管瘤伴鞍区和鞍旁延伸的乳头水肿伴急性深度视力丧失——三种罕见的表现

4区医学

Neurology Asia Pub Date : 2023-09-01 DOI: 10.54029/2023hxu

Khalilah Mastura Zahari, Nurul 'Ain Masnon, Othmaliza Othman, Kartikasalwah Abd Latif, Noraini Mohd Dusa

引用次数: 0

A case of herpes zoster-related phrenic nerve palsy: Effect of home-based pulmonary rehabilitation 带状疱疹相关性膈神经麻痹1例:家庭肺康复的效果

4区医学

Neurology Asia Pub Date : 2023-09-01 DOI: 10.54029/2023znv

Seongeun Park, Ji Cheol Shin, Kye Hee Cho, Sang Hee Im

{"title":"A case of herpes zoster-related phrenic nerve palsy: Effect of home-based pulmonary rehabilitation","authors":"Seongeun Park, Ji Cheol Shin, Kye Hee Cho, Sang Hee Im","doi":"10.54029/2023znv","DOIUrl":"https://doi.org/10.54029/2023znv","url":null,"abstract":"Here, we report the case of a 62-year-old man with herpes zoster-related phrenic nerve palsy, which was evident in clinical, radiological, and electrodiagnostic studies. To aid clinical recovery and preserve pulmonary function, we designed a home-based pulmonary rehabilitation program consisting of air-stacking exercises using ambu-bagging, respiratory muscle training to improve the strength and endurance of inspiratory and expiratory muscles, and aerobic and resistance exercises of the upper and lower limbs to improve and prevent the decline of cardiorespiratory fitness. The patient was monitored, and the exercises were adjusted through regular outpatient follow-up. During the overall follow-up period of 26 months, pulmonary rehabilitation led to an increase in forced vital capacity from 2,020 to 3,160 mL, and improved the diaphragmatic height index from -4.46 to 0.28. Clinical symptoms also showed notable improvement, as the Borg Rating of Perceived Exertion scale score decreased from 17 to 7. We found that a home-based, self-performed pulmonary rehabilitation program could promote recovery from herpes zoster-related phrenic nerve palsy. Not only is this important for the rapid restoration of respiratory function and symptomatic relief, it can also protect patients from respiratory complications.","PeriodicalId":49757,"journal":{"name":"Neurology Asia","volume":"30 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135637963","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

RNF213 p.R4810K variant in moyamoya disease in adults and children from a Malaysian tertiary center 马来西亚三级中心成人和儿童烟雾病的RNF213 p.R4810K变异

4区医学

Neurology Asia Pub Date : 2023-09-01 DOI: 10.54029/2023jsj

Jun Hui Ho, Kay Sin Tan, Wei Kang Lim, Choong Yi Fong, Tsun Haw Toh, Kar Foo Lau, Zhen Shun Chan, Sharon Mei Ling Tai, Kartini Rahmat, Farah Diana Tarmizi Thayaparan, Sumitha Murugesu, Ching Ching Ng

{"title":"RNF213 p.R4810K variant in moyamoya disease in adults and children from a Malaysian tertiary center","authors":"Jun Hui Ho, Kay Sin Tan, Wei Kang Lim, Choong Yi Fong, Tsun Haw Toh, Kar Foo Lau, Zhen Shun Chan, Sharon Mei Ling Tai, Kartini Rahmat, Farah Diana Tarmizi Thayaparan, Sumitha Murugesu, Ching Ching Ng","doi":"10.54029/2023jsj","DOIUrl":"https://doi.org/10.54029/2023jsj","url":null,"abstract":"Background: Ring finger protein 213 (RNF213) is a major susceptibility gene for moyamoya disease (MMD). A single nucleotide variant known as c.14429G>A (p.R4810K, rs112735431) is strongly associated with MMD, weakly associated with moyamoya syndrome (MMS) and intracranial atherosclerosis (ICAS) in East Asians. The percentage of patients carrying p.R4810K and the effect sizes vary between different racial backgrounds. We aimed to investigate the prevalence of p.R4810K in MMD, MMS, and ICAS patients in Malaysia. Methods: We genotyped p.R4810K in DNA extracted from 9 MMD, 13 MMS, 15 ICAS cases, and 45 controls using TaqMan SNP genotyping assay. Clinical and neuroradiological data was collected for each patient and the distribution of genotype frequencies compared between cases and controls and tested for association. Results: Two of seven (28.6%) Chinese MMD cases had heterozygous p.R4810K (GA) genotype. The remaining MMD cases (5 Chinese and 2 Malays), all 13 MMS, 15 ICAS cases and 45 controls had homozygous wild-type (GG) genotype. Higher frequency of GA genotype was observed in Chinese MMD patients compared with controls, indicating an association between p.R4810K and Chinese MMD subgroup under a dominant model (P=0.0398). Conclusion: This is the first study reporting p.R4810K in a multiracial Asian population. The p.R4810K missense mutation was detected in MMD cases of Chinese descent in Malaysia. Further studies are needed to identify other susceptibility variants and genes in Malaysian patients with moyamoya and ICAS.","PeriodicalId":49757,"journal":{"name":"Neurology Asia","volume":"44 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135637964","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effects of virtual balance training and conservative rehabilitation on balance in chronic stroke patients 虚拟平衡训练与保守性康复对慢性脑卒中患者平衡能力的影响

4区医学

Neurology Asia Pub Date : 2023-09-01 DOI: 10.54029/2023kcw

SERDAR KILINC, Chasan Mola ALİ, Isıl Doganer, Elif Yaksi, Ferda Ozdemir

{"title":"Effects of virtual balance training and conservative rehabilitation on balance in chronic stroke patients","authors":"SERDAR KILINC, Chasan Mola ALİ, Isıl Doganer, Elif Yaksi, Ferda Ozdemir","doi":"10.54029/2023kcw","DOIUrl":"https://doi.org/10.54029/2023kcw","url":null,"abstract":"Objective: This study aimed to test the comparative efficacy of virtual balance training (VBT) and conservative rehabilitation (CR) relative to CR alone on balance in chronic stroke patients. Methods: Thirty patients with chronic stroke (>6-months post-stroke) were allocated into 2 groups (n=15) as Group CR and Group VBT. CR was performed for 60 min, 4 times a week, for 8 weeks in both groups. VBT was applied for 20 min, 4 times a week, for 8 weeks along with the CR, in Group VBT. Brunnstrom motor recovery (BMR) stage, spasticity degrees, Functional Ambulation Scale (FAS), Short Form-36 (SF-36) scale, Berg Balance Scale (BBS) in both groups were assessed before and after treatment. Mann-Whitney U, Wilcoxon signed rank tests were used to evaluate BBS data (p<0.05). Results: Although, no significant difference was observed between groups in terms of BBS scores, BMR stages, FAS scores, SF-36 scale scores, and spasticity degrees before and after treatment; significant improvements were observed in BBS scores, BMR stages, and FAS scores after treatment in both groups (p<0.05). Comparing the SF-36 subscale scores before and after treatment, significant differences were noted in emotional role limitation scores for Group VBT (p=0.03) and in pain scores for Group CR (p=0.01). Conclusion: VBT along with the CR in chronic stroke patients was not superior to the CR alone, in terms of improving balance, motor recovery, ambulation level, and quality of life.","PeriodicalId":49757,"journal":{"name":"Neurology Asia","volume":"25 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135638080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0