Neurology Asia最新文献_第2页

Immature granulocyte and other markers in prediction of the short-term and long-term prognosis of patients with acute ischemic stroke 预测急性缺血性脑卒中患者短期和长期预后的未成熟粒细胞和其他标志物

IF 0.2 4区医学

Neurology Asia Pub Date : 2023-12-01 DOI: 10.54029/2023dcd

Idris Kocatürk, Sedat Gülten

{"title":"Immature granulocyte and other markers in prediction of the short-term and long-term prognosis of patients with acute ischemic stroke","authors":"Idris Kocatürk, Sedat Gülten","doi":"10.54029/2023dcd","DOIUrl":"https://doi.org/10.54029/2023dcd","url":null,"abstract":"Background & Objectives: To evaluate immature granulocytes, a new inflammatory biomarker, and other markers in short- and long-term prognosis in patients with acute ischemic stroke (AIS). Methods: Laboratory information system data from a tertiary hospital in Turkiye were used in this retrospective study. Of the 327 patients with the diagnosis of AIS, 275 recovered, and 52 died. It was determined that 31 of these 275 patients, who were followed up retrospectively, died within 12 months after discharge. Routinely measured immature granulocyte (IG), other hemogram parameters in the Sysmex XN 1000 (XN-1000-Hematology-Analyzer-Sysmex Corporation, Japan), and demographic data were statistically compared in both groups. We tried to estimate the short- and long-term mortality from the blood samples of these patients at their first admission to the hospital. Results: Of the patients included in the study, 150 (45.9%) were female, and 177 (54.1%) were male. National Institutes Of Health Stroke Scale (NIHSS) (AUC=960), length of stay (AUC=791), red blood cell distribution width – standard deviation (RDW-CV) (AUC=728), and IG (AUC=712) were the most effective parameters in predicting short-term mortality, while age (AUC=764) in predicting long-term mortality was the most effective parameters. Conclusion: IG, together with NIHSS and length of stay, shows moderate and high predictive properties in prognosticating short-term mortality but is ineffective in prognosticating long-term mortality. Age was found to be the most predictive marker for long-term mortality.","PeriodicalId":49757,"journal":{"name":"Neurology Asia","volume":"27 15","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139188895","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation of intracranial atherosclerotic disease risk factors in patients with acute ischemic stroke 评估急性缺血性脑卒中患者颅内动脉粥样硬化疾病的危险因素

IF 0.2 4区医学

Neurology Asia Pub Date : 2023-12-01 DOI: 10.54029/2023xhu

Yasemin Dinç, R. Ozpar, Gizem Mesut, Farid Hojjati, B. Hakyemez, Mustafa Bakar

引用次数: 0

Predictors associated with stroke after coronary artery bypass grafting in Turkish population 土耳其人冠状动脉旁路移植术后中风的相关预测因素

IF 0.2 4区医学

Neurology Asia Pub Date : 2023-12-01 DOI: 10.54029/2023apk

Esra Eruyar, Kaan Kaya

{"title":"Predictors associated with stroke after coronary artery bypass grafting in Turkish population","authors":"Esra Eruyar, Kaan Kaya","doi":"10.54029/2023apk","DOIUrl":"https://doi.org/10.54029/2023apk","url":null,"abstract":"Background Objective: Postoperative stroke is a serious adverse event, a major cause of morbidity and mortality after coronary artery bypass grafting (CABG). This study is designed to determine the incidence of stroke after CABG and to identify the preoperative, intraoperative and postoperative risk factors associated with the development of a stroke. Methods: Between January 2019 and December 2022, 1.555 CABG were performed. Retrospective analysis of the patient files revealed that 24 (1.48%) patients had stroke in the postoperative period. Variables were compared with patients without neurological deficits (n=50) who had undergone CABG. Predictors of preoperative, intraoperative and postoperative stroke were identified. Results: The incidence of postoperative stroke was 1.48% (n=24). Mean age of these patients was 63.86 ± 8.58 years, and 59 (79.7%) were males. Chronic renal failure (p= 0.011), previous CABG (p=0.009), carotid artery disease (p=0.009), CRP levels (p=0.004) and Monocyte/Lymphocyte ratio (p=0.019) were identified as important preoperative risk factors for stroke development but there were no diffirence prevalence of age, sex, diabetes, hypertension, congestive heart failure and atrial fibrillation. Conclusion: Five variables (chronic renal failure, prior CABD, prior carotid artery disease, preoperative CRP levels and Monocyte/Lymphocyte ratio were found as risk factors for stroke after CABG. The development of postoperative stroke is associated with multiple morbidities and increased mortality. Careful assessment and management of risk factors should be implemented to reduce this important complication after CABG.","PeriodicalId":49757,"journal":{"name":"Neurology Asia","volume":"15 2","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139189871","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A rare epilepsy phenotype in Gabriele-de Vries syndrome: A new case and literature review 加布里埃尔-德-弗里斯综合征的罕见癫痫表型：一个新病例和文献综述

IF 0.2 4区医学

Neurology Asia Pub Date : 2023-12-01 DOI: 10.54029/2023eat

Hyewon Woo, Won Seop Kim, Jon Soo Kim

引用次数: 0

Centronuclear myopathy with a novel variant (p.Asp646Tyr) in the DNM2 gene exhibits mild clinical manifestations: A case report 患有 DNM2 基因新型变异体（p.Asp646Tyr）的中心核肌病临床表现轻微：病例报告

IF 0.2 4区医学

Neurology Asia Pub Date : 2023-12-01 DOI: 10.54029/2023feu

Youngho Kim, M. Kwack, Jong-Mok Lee

引用次数: 0

Clinical, radiological profile and outcomes of patients with idiopathic intracranial hypertension: a prospective study in the South Indian population 特发性颅内高压患者的临床、放射学特征和预后：一项针对南印度人群的前瞻性研究

IF 0.2 4区医学

Neurology Asia Pub Date : 2023-12-01 DOI: 10.54029/2023ijr

Mohamed Azharudeen, Ravi Lalapet Anbazhagan, Kannan Vellaichamy, Chandramouleeswaran Venkatraman, Balasubramanian Samivel

{"title":"Clinical, radiological profile and outcomes of patients with idiopathic intracranial hypertension: a prospective study in the South Indian population","authors":"Mohamed Azharudeen, Ravi Lalapet Anbazhagan, Kannan Vellaichamy, Chandramouleeswaran Venkatraman, Balasubramanian Samivel","doi":"10.54029/2023ijr","DOIUrl":"https://doi.org/10.54029/2023ijr","url":null,"abstract":"Objective: To describe the clinical, radiological characteristics and outcomes of patients with Idiopathic intracranial hypertension (IIH) at 6 months in a cohort of South Indian patients. Methods: We did a prospective study on patients presented to our institute with the symptomatology of IIH. A detailed history regarding headache, visual symptoms were noted. A complete neurological examination including examination of the fundus, CSF opening pressure, MRI brain, and MR cerebral venography were performed for all subjects. The patients were followed-up for 6 months to assess treatment response. Results: We evaluated 49 patients, the majority were females, and 38.7% had grade 1 obesity. Headache was the most common clinical presentation. The most common MRI abnormality was empty sella turcica, noted in 47%. There was a significant positive correlation between CSF opening pressure and headache severity (R2= 0.165, p = 0.018), as well as between CSF opening pressure and the grade of papilledema (R2=0.245, p=0.001). Of the cases, 95% responded to medical management, and three patients of fulminant IIH underwent lumbar-peritoneal shunting. At 6 months, 60% had persistent headaches. Only 8.7% had persistent visual symptoms, and only one had optic atrophy. There was no significant correlation between the follow-up grade of papilledema and the patient’s BMI. No significant correlation was found between the amount of weight lost and the improvement in the Numerical Rating Scale (NRS) score at 6 months. Conclusion: Headache in IIH is multifactorial and a significant cause of disability. The overall prognosis for vision is good. IIH should be suspected in any obese woman with headaches since it is one of the preventable causes of blindness.","PeriodicalId":49757,"journal":{"name":"Neurology Asia","volume":"176 7","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139195755","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Mitochondrial DNA 3252A>G mutation presenting as MERRF/MELAS overlapping syndrome: A case report 线粒体 DNA 3252A>G 突变表现为 MERRF/MELAS 重叠综合征：病例报告

IF 0.2 4区医学

Neurology Asia Pub Date : 2023-12-01 DOI: 10.54029/2023tzs

Yin Yin Tan, Ting Yoong Tee, Farn Ye Chew, Huey Tean Kok, Nor Haizura Abd Rani, L. Ngu, Shanthi Viswanathan

引用次数: 0

Phenotypic comparison of a novel variant (p.P164R) and A founder mutation (c.748+1G>A) in Warburg Micro syndrome 沃伯格微小病变综合征新型变体（p.P164R）与奠基突变（c.748+1G>A）的表型比较

IF 0.2 4区医学

Neurology Asia Pub Date : 2023-12-01 DOI: 10.54029/2023htk

Tayfun Çinleti, Gamze Sarıkaya Uzan, Büşra Bürçe, Yağmur Küçümen, Hatice Yelda Yalçın, S. Gürsoy, U. Yiş, A. Çağlayan, Özlem GİRAY BOZKAYA

引用次数: 0

The impact of COVID-19 on people with epilepsy is not over, a longitudinal study 一项纵向研究显示，COVID-19 对癫痫患者的影响尚未结束

IF 0.2 4区医学

Neurology Asia Pub Date : 2023-12-01 DOI: 10.54029/2023xhk

M. Koh, Kheng Seang Lim, Si-Lei Fong, Christine Audrey, Xuen Yu, Chong-Tin Tan

{"title":"The impact of COVID-19 on people with epilepsy is not over, a longitudinal study","authors":"M. Koh, Kheng Seang Lim, Si-Lei Fong, Christine Audrey, Xuen Yu, Chong-Tin Tan","doi":"10.54029/2023xhk","DOIUrl":"https://doi.org/10.54029/2023xhk","url":null,"abstract":"Background: Despite the shift of the COVID-19 era, the post-pandemic impacts on healthcare for people with epilepsy (PWE) remain unknown. This study aimed to determine the clinical, logistic, and psychological impacts of the COVID-19 pandemic during and after COVID-19 containment measures. Method: This is a longitudinal study over two years. Clinical and psychological outcomes of COVID-19 were assessed with the Hospital Anxiety Depression Scale (HADS) and Quality of Life in Epilepsy Inventory (QOLIE-31). Result: A total of 239 patients were recruited, with a mean age of 38.32±14.16 years, and 51.5% were male. Seventy-nine (33.1%) were previously infected with COVID-19. As compared to during the COVID-19 pandemic, the percentage of patients who reported seizure worsening (13.0%) remained the same after the pandemic. The main reasons associated with seizure worsening include baseline seizure frequency ≥1 per month (54.8%), stress (61.3%) and fatigue (48.4%), despite more accessible clinic appointments (49.4%), medication supply (67.8%) and emergency units (62.8%). Psychologically, after the COVID-19 pandemic, PWE reported similar anxiety (4.65±4.46 vs. 4.78±3.72, p=0.715) and depression scores (3.81±3.97 vs. 3.86±3.52, p=0.869) than during the pandemic. Despite improvement in clinical and logistics factors, PWE experiences worsening in quality of life (57.44±15.41 vs. 61.70±15.05, p=<.001), especially in the emotional well-being, cognitive, medication effects, and social function subscales. Conclusion: Despite the improvement in clinical and medication access in the post-COVID-19 era, the challenges and consequences of the pandemic remained, without an improvement in seizure control and psychological well-being, and worsening quality of life.","PeriodicalId":49757,"journal":{"name":"Neurology Asia","volume":"19 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139192249","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The effect of internet-based telehealth nursing on the quality of life in patients with atrial fibrillation and stroke 基于互联网的远程医疗护理对心房颤动和中风患者生活质量的影响

IF 0.2 4区医学

Neurology Asia Pub Date : 2023-12-01 DOI: 10.54029/2023hdr

Meng Zhang, Wei Guo

{"title":"The effect of internet-based telehealth nursing on the quality of life in patients with atrial fibrillation and stroke","authors":"Meng Zhang, Wei Guo","doi":"10.54029/2023hdr","DOIUrl":"https://doi.org/10.54029/2023hdr","url":null,"abstract":"Background: The purpose of this study is to determine if patients with atrial fibrillation and stroke can benefit from receiving care at home under the supervision of remote specialist nurses through internet-based telehealth nursing. Methods: We selected a total of 168 patients with atrial fibrillation and stroke, who were treated in our hospital from January 2018 to December 2019. The patients were divided into a traditional at-home self-help nursing group (the control group) and an internet-based telehealth nursing group involving specialist nurses based on the post-discharge convalescence nursing modes (the experimental group). The patients were followed up and observed for 12 months, and the survival rate, readmission rate, daily life activities, limb motor ability, psychological state, cardiac function and rhythm control, adverse event rate, and the nursing satisfaction of the patients and their families were evaluated for the two different nursing modes. Results: Compared with traditional at- home nursing, internet-based telehealth nursing provided by specialist nurses resulted in a significant improvement in the survival rate of patients. Additionally, the readmission due to atrial fibrillation or stroke was significantly reduced, the daily activities and limb motor ability were significantly improved, the patients’ anxiety and depression were reduced, and the cardiac function index and rhythm control showed obvious improvement. In addition, the rates of bedsores and minor hemorrhage events were lower, and the nursing satisfaction levels of the patients and their families were significantly higher. Conclusion: Patients with atrial fibrillation and stroke benefit greatly from internet-based telehealth nursing provided by specialized nurses, both in terms of prognosis and quality of life. As a result, this approach to nursing care deserves wider adoption and dissemination.","PeriodicalId":49757,"journal":{"name":"Neurology Asia","volume":"174 2","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139188172","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0