Neuropsychology Review最新文献

{"title":"Memory Function and Huntington's Disease: A Systematic Review.","authors":"Justin Guillot, Mohamad El Haj, Christophe Verny, Philippe Allain","doi":"10.1007/s11065-025-09679-1","DOIUrl":"https://doi.org/10.1007/s11065-025-09679-1","url":null,"abstract":"<p><p>This systematic review aimed to identify preserved and impaired memory processes in Huntington's disease (HD), with consideration of disease stage and the specific memory subsystems assessed. A systematic search was conducted in PubMed, ScienceDirect, and Google Scholar up to March 11, 2025. Eligible studies had to be peer-reviewed, had to involve participants aged 18 or older, had to include patients with genetically or clinically confirmed HD, and had to be published in English or French. Risk of bias was assessed using the ROBINS-I tool. A structured narrative synthesis was performed across seven memory subsystems and clinical stages (pre-manifest vs. manifest), and findings were summarized using tables and figures. A total of 136 studies were included. Verbal episodic memory impairments were consistently observed from early stages, particularly in free recall, while recognition was initially preserved. Visual episodic memory showed progressive deficits. Olfactory memory, though rarely examined, appeared to be impaired early. Autobiographical memory was underinvestigated but showed signs of disruption, seemingly independent of executive dysfunction. Semantic memory was generally preserved but showed reduced access without cues. Early-stage impairments were also reported in working memory. Priming was preserved, while complex procedural learning tasks showed variable deficits. Many studies presented methodological limitations, including confounding and lack of blinding. Memory profiles in HD appear heterogeneous and subsystem-specific. Autobiographical memory may constitute a distinct cognitive marker. Improved characterization of memory deficits is crucial to guide the development of targeted cognitive interventions.</p>","PeriodicalId":49754,"journal":{"name":"Neuropsychology Review","volume":" ","pages":""},"PeriodicalIF":5.0,"publicationDate":"2025-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145607172","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring the Predictive Role of Early Executive Functions and Self-Regulation on Functional Outcome in Neurodevelopmental Disorders: A Systematic Review and Meta-analysis.","authors":"Berni M, Scatigna S, Igliozzi R, Mazzotti S, Calderoni S, Martinelli A, Tancredi R, Guzzetta A, Pecini C","doi":"10.1007/s11065-025-09683-5","DOIUrl":"https://doi.org/10.1007/s11065-025-09683-5","url":null,"abstract":"<p><p>Executive functions and self-regulation, which are the control processes relevant for learning and adaptation, are frequently impaired in neurodevelopmental disorders (NDDs). Research on the role of early executive functions and self-regulation in the diagnosis and developmental trajectories of NDDs has grown rapidly in recent years, necessitating a synthesis of the evidence strength and the methodologies used to investigate the relationship between executive functions/self-regulation and the functional profiles of NDDs. This systematic review and meta-analysis examined 32 studies that used longitudinal designs to investigate the relationship between executive functions and self-regulation in the first 6 years of life and NDDs symptoms from ages 3 to 18. Separate meta-analyses were conducted for the statistical methods used, as well as for ADHD and ASD diagnoses, types of executive function and self-regulation measures, and the developmental periods during which they were assessed. The results highlight a significant longitudinal association between early executive and self-regulation difficulties and later impairments in attention, socio-communication, and adaptive functioning in NDDs. The findings also support the predictive value of these early difficulties and the need to consider the methodological characteristics of the studies. Although these findings predominantly concern specific diagnostic categories, such as attention-deficit/hyperactivity disorder and autism spectrum disorder, they could have important implications for several conditions of atypical neurodevelopment, especially for the prevention of symptoms and associated psychopathological exacerbation. Given the methodological variability of the studies, the results of this review can also help in defining more appropriate tools and statistical methodologies for future research.</p>","PeriodicalId":49754,"journal":{"name":"Neuropsychology Review","volume":" ","pages":""},"PeriodicalIF":5.0,"publicationDate":"2025-11-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145543695","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Neurofunctional Correlates of Morphosyntactic and Thematic Impairments in Aphasia: A Systematic Review and Meta-analysis.","authors":"Sabrina Beber, Giorgia Bontempi, Gabriele Miceli, Marco Tettamanti","doi":"10.1007/s11065-024-09648-0","DOIUrl":"10.1007/s11065-024-09648-0","url":null,"abstract":"<p><p>Lesion-symptom studies in persons with aphasia showed that left temporoparietal damage, but surprisingly not prefrontal damage, correlates with impaired ability to process thematic roles in the comprehension of semantically reversible sentences (The child is hugged by the mother). This result has led to challenge the time-honored view that left prefrontal regions are critical for sentence comprehension. However, most studies focused on thematic role assignment and failed to consider morphosyntactic processes that are also critical for sentence processing. We reviewed and meta-analyzed lesion-symptom studies on the neurofunctional correlates of thematic role assignment and morphosyntactic processing in comprehension and production in persons with aphasia. Following the PRISMA checklist, we selected 43 papers for the review and 27 for the meta-analysis, identifying a set of potential bias risks. Both the review and the meta-analysis confirmed the correlation between thematic role processing and temporoparietal regions but also clearly showed the involvement of prefrontal regions in sentence processing. Exploratory meta-analyses suggested that both thematic role and morphosyntactic processing correlate with left prefrontal and temporoparietal regions, that morphosyntactic processing correlates with prefrontal structures more than with temporoparietal regions, and that thematic role assignment displays the opposite trend. We discuss current limitations in the literature and propose a set of recommendations for clarifying unresolved issues.</p>","PeriodicalId":49754,"journal":{"name":"Neuropsychology Review","volume":" ","pages":"483-516"},"PeriodicalIF":5.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12602653/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142114123","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cognitive Correlates of Risky Decision-Making in Individuals with and without ADHD: A Meta-analysis.","authors":"Vahid Nejati, Aida Peyvandi, Nasim Nazari, Mahshid Dehghan","doi":"10.1007/s11065-024-09646-2","DOIUrl":"10.1007/s11065-024-09646-2","url":null,"abstract":"<p><p>This meta-analytic study aims to investigate the cognitive correlates of risky decision-making in individuals with attention-deficit/hyperactivity disorder (ADHD) and typically developing (TD) individuals. A systematic analysis of existing literature was conducted, encompassing 38 studies (496 ADHD and 1493 TD). Findings revealed a consistent propensity for riskier decision-making in individuals with ADHD, supported by significant correlations with attention, cognitive flexibility, inhibitory control, time perception, and working memory. The study underscores the relevance of these cognitive functions in shaping decision-making tendencies, with nuanced patterns observed within the ADHD and TD subgroups. Individuals with ADHD often demonstrate altered patterns of correlation, reflecting the specific cognitive challenges characteristic of the disorder.</p>","PeriodicalId":49754,"journal":{"name":"Neuropsychology Review","volume":" ","pages":"535-551"},"PeriodicalIF":8.2,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141433225","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Verbal and Spatial Working Memory Capacity in Blind Adults and the Possible Influence of Age at Blindness Onset: A Systematic Review and Meta-analysis.","authors":"Marta Sepúlveda-Palomo, David Del Río, Dolores Villalobos, Santiago Fernández González","doi":"10.1007/s11065-024-09651-5","DOIUrl":"10.1007/s11065-024-09651-5","url":null,"abstract":"<p><p>The loss of a sense, such as vision, forces individuals to adapt to their environment and its demands in a variety of ways. In the case of blindness, significant neurofunctional and cognitive changes have been documented. However, there is no clear consensus on the differences in performance between adult blind participants and sighted controls in cognitive processes such as working memory (WM). Two variables are important, including the cognitive task used to measure working memory and the age at which vision loss occurs. This review is aimed at exploring potential disparities in verbal and spatial WM performance between blind and sighted adults, as well as understanding how these differences may be influenced by the age of vision loss. A systematic search across PsycArticles, PsycInfo, Medline, and Web of Science databases identified 21 pertinent studies. The studies were categorized, and effect sizes were calculated through meta-analysis, distinguishing between verbal (auditory simple forward and backward span, complex span, and n-back) and visuospatial WM tasks (adapted Corsi-block and simple storage tasks, imagery tasks, and complex storage tasks). Visual sensory loss induces adaptations affecting WM function in blind participants. In the verbal domain, improved phonological processing and/or serial item position encoding might facilitate WM retrieval. In contrast, in spatial WM, an over-reliance on serial processing may hinder strategic grouping in blind individuals. This review highlights the need to further explore the role of age at the time of vision loss. Although evidence suggests that adaptations to serial processing may be more pronounced in early development, particularly in comparison to those who become blind in adulthood, the available data are limited. The study calls for further research to deepen our understanding of cognitive adaptations and their temporal dynamics in response to vision loss.</p>","PeriodicalId":49754,"journal":{"name":"Neuropsychology Review","volume":" ","pages":"569-587"},"PeriodicalIF":8.2,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142479141","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reliability of Theory of Mind Tasks in Schizophrenia, ASD, and Nonclinical Populations: A Systematic Review and Reliability Generalization Meta-analysis.","authors":"Harry Kam Hung Tsui, Ting Yat Wong, Chak Fai Ma, Ting Eva Wong, Janet Hsiao, Sherry Kit Wa Chan","doi":"10.1007/s11065-024-09652-4","DOIUrl":"10.1007/s11065-024-09652-4","url":null,"abstract":"<p><p>Though theory of mind (ToM) is an important area of study for different disciplines, however, the psychometric evaluations of ToM tasks have yielded inconsistent results across studies and populations, raising the concerns about the accuracy, consistency, and generalizability of these tasks. This systematic review and meta-analysis examined the psychometric reliability of 27 distinct ToM tasks across 90 studies involving 2771 schizophrenia (SZ), 690 autism spectrum disorder (ASD), and 15,599 nonclinical populations (NC). Findings revealed that while all ToM tasks exhibited satisfactory internal consistency in ASD and SZ, about half of them were not satisfactory in NC, including the commonly used Reading the Mind in the Eye Test and Hinting Task. Other than that, Reading the Mind in the Eye Test showed acceptable reliability across populations, whereas Hinting Task had poor test-retest reliability. Notably, only Faux Pas Test and Movie for the Assessment of Social Cognition had satisfactory reliability across populations albeit limited numbers of studies. However, only ten studies examined the psychometric properties of ToM tasks in ASD adults, warranting additional evaluations. The study offered practical implications for selecting ToM tasks in research and clinical settings, and underscored the importance of having a robust psychometric reliability in ToM tasks across populations.</p>","PeriodicalId":49754,"journal":{"name":"Neuropsychology Review","volume":" ","pages":"552-568"},"PeriodicalIF":8.2,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12602658/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142394749","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cognitive Training During Midlife: A Systematic Review and Meta-Analysis.","authors":"Chen Zhu, Shalini Arunogiri, Qi Li, Elizabeth H X Thomas, Caroline Gurvich","doi":"10.1007/s11065-024-09649-z","DOIUrl":"10.1007/s11065-024-09649-z","url":null,"abstract":"<p><p>Midlife has been suggested to be a crucial time to introduce interventions for improving cognitive functions. The effects of cognitive training (CT) in healthy middle-aged populations and more specifically during the menopausal transition have not been systematically investigated. To investigate the effects of CT on cognition in healthy middle-aged adults and specifically in females during the menopause transition, literature was searched inception to July 2023 and studies were included that examined the effects of CT on a defined cognitive outcome. The improvement on cognitive performance following CT was the main outcome measured as mean difference (from baseline to immediate post) estimates with corresponding 95% confidence intervals (CI) in meta-analysis and was discussed with the support of subgroup analysis based on outcome type (i.e., far or near-transfer) and cluster tabulations. Nineteen articles were included in the qualitative synthesis with a total of 7765 individuals, and eight articles were included in the meta-analyses. CT was categorized into six type clusters: Game-based CT, General CT, Speed of Processing Training, Working Memory Training, Strategy-based CT, and Cognitive Remediation. Cognitive outcome was divided into six clusters: working memory, verbal memory, language, executive function, attention/processing speed, and visual memory. Meta-analysis reported significant improvement in the domain of executive function (0.48, 95% CI 0.08-0.87), verbal memory (0.22, 95% CI 0.11-0.33), and working memory (0.16, 95% CI 0.05-0.26). CT confers benefits on various cognitive domains, suggesting a potential role of CT to promote optimal cognitive functioning in the midlife and specifically in women during the menopause transition.</p>","PeriodicalId":49754,"journal":{"name":"Neuropsychology Review","volume":" ","pages":"427-448"},"PeriodicalIF":5.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12602558/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142134279","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Implementation of Cognitive (Neuropsychological) Interventions for Older Adults in Clinical or Community Settings: A Scoping Review.","authors":"Kerryn E Pike, Lily Li, Sharon L Naismith, Alex Bahar-Fuchs, Alessandra Lee, Inga Mehrani, Adam Bentvelzen, Nicola T Lautenschlager, Megan E O'Connell, Irene Blackberry, Loren Mowszowski","doi":"10.1007/s11065-024-09650-6","DOIUrl":"10.1007/s11065-024-09650-6","url":null,"abstract":"<p><p>Despite compelling evidence that cognitive interventions for older adults improve cognition, mood, and everyday function, few are implemented in clinical or community practice. This scoping review aims to understand the implementation frameworks and methods used and their contribution to implementation success of cognitive interventions for older adults. We followed the Preferred Reporting Items for Systematic Reviews and Meta-analysis extension for Scoping Reviews (PRISMA-ScR), and searched CINAHL, EMBASE, MEDLINE, and PSYCINFO databases, using terms related to cognitive interventions, implementation, and older adults. This resulted in 5002 studies, of which 29 were included following an iterative process. Most studies reported on implementation of cognitive stimulation for people with dementia. Only four studies used formal implementation frameworks, with three using RE-AIM, and one a process evaluation using complexity theory. The most frequently addressed implementation concepts were Acceptability, Feasibility, and Effectiveness, while Cost, Cost-Effectiveness, and Maintenance were rarely reported. Solutions to common barriers included the importance of good stakeholder relationships and engagement, a manualised intervention flexible enough to adapt to the context, and ensuring facilitators were well-trained, confident, and enthusiastic.</p>","PeriodicalId":49754,"journal":{"name":"Neuropsychology Review","volume":" ","pages":"588-616"},"PeriodicalIF":8.2,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12602636/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142584764","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Object Recognition Memory Deficits in ADHD: A Meta-analysis.","authors":"Francisco José Lobato-Camacho, Luís Faísca","doi":"10.1007/s11065-024-09645-3","DOIUrl":"10.1007/s11065-024-09645-3","url":null,"abstract":"<p><p>Object recognition memory allows us to identify previously seen objects. This type of declarative memory is a primary process for learning. Despite its crucial role in everyday life, object recognition has received far less attention in ADHD research compared to verbal recognition memory. In addition to the existence of a small number of published studies, the results have been inconsistent, possibly due to the diversity of tasks used to assess recognition memory. In the present meta-analysis, we have collected studies from Web of Science, Scopus, PubMed, and Google Scholar databases up to May 2023. We have compiled studies that assessed visual object recognition memory with specific visual recognition tests (sample-match delayed tasks) in children and adolescents diagnosed with ADHD. A total of 28 studies with 1619 participants diagnosed with ADHD were included. The studies were assessed for risk of bias using the Quadas-2 tool and for each study, Cohen's d was calculated to estimate the magnitude of the difference in performance between groups. As a main result, we have found a worse recognition memory performance in ADHD participants when compared to their matched controls (overall Cohen's d ~ 0.492). We also observed greater heterogeneity in the magnitude of this deficit among medicated participants compared to non-medicated individuals, as well as a smaller deficit in studies with a higher proportion of female participants. The magnitude of the object recognition memory impairment in ADHD also seems to depend on the assessment method used.</p>","PeriodicalId":49754,"journal":{"name":"Neuropsychology Review","volume":" ","pages":"517-534"},"PeriodicalIF":8.2,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141441044","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Systematic Review and Meta-Analysis of Social Cognition Among People Living with HIV: Implications for Non-Social Cognition and Social Everyday Functioning.","authors":"David E Vance, Rebecca Billings, Crystal Chapman Lambert, Pariya L Fazeli, Burel R Goodin, Mirjam-Colette Kempf, Leah H Rubin, Bulent Turan, Jenni Wise, Gerhard Hellemann, Junghee Lee","doi":"10.1007/s11065-024-09643-5","DOIUrl":"10.1007/s11065-024-09643-5","url":null,"abstract":"<p><p>Social cognition-the complex mental ability to perceive social stimuli and negotiate the social environment-has emerged as an important cognitive ability needed for social functioning, everyday functioning, and quality of life. Deficits in social cognition have been well documented in those with severe mental illness including schizophrenia and depression, those along the autism spectrum, and those with other brain disorders where such deficits profoundly impact everyday life. Moreover, subtle deficits in social cognition have been observed in other clinical populations, especially those that may have compromised non-social cognition (i.e., fluid intelligence such as memory). Among people living with HIV (PLHIV), 44% experience cognitive impairment; likewise, social cognitive deficits in theory of mind, prosody, empathy, and emotional face recognition/perception are gradually being recognized. This systematic review and meta-analysis aim to summarize the current knowledge of social cognitive ability among PLHIV, identified by 14 studies focused on social cognition among PLHIV, and provides an objective consensus of the findings. In general, the literature suggests that PLHIV may be at-risk of developing subtle social cognitive deficits that may impact their everyday social functioning and quality of life. The causes of such social cognitive deficits remain unclear, but perhaps develop due to (1) HIV-related sequelae that are damaging the same neurological systems in which social cognition and non-social cognition are processed; (2) stress related to coping with HIV disease itself that overwhelms one's social cognitive resources; or (3) may have been present pre-morbidly, possibly contributing to an HIV infection. From this, a theoretical framework is proposed highlighting the relationships between social cognition, non-social cognition, and social everyday functioning.</p>","PeriodicalId":49754,"journal":{"name":"Neuropsychology Review","volume":" ","pages":"381-410"},"PeriodicalIF":5.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12328480/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141312059","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}